Significance of cell proliferation index in assessing histological prognostic categories in Hodgkin's disease: An immunohistochemical study with Ki67 and MIB-1 monoclonal antibodies

Haematologica

Volumn 82, Issue 3, 1997, Pages 281-285

  Abele, Maria Cristina ^a   Valente, Guido ^a,c   Kerim, Simonetta ^a   Navone, Roberto ^a   Onesti, Piera ^a   Chiusa, Luigi ^a   Resegotti, Luigi ^b   Palestro, Giorgio ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b MOLINETTE HOSPITAL   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

Growth fraction; Hodgkin's disease; Immunohistochemistry; Ki67; MIB 1

Indexed keywords

MONOCLONAL ANTIBODY KI 67;

ARTICLE; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CELL PROLIFERATION; HISTOPATHOLOGY; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PROGNOSIS;

ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; ANTIGENS, NUCLEAR; BIOLOGICAL MARKERS; CELL DIVISION; DISEASE-FREE SURVIVAL; HODGKIN DISEASE; HUMANS; KI-67 ANTIGEN; NUCLEAR PROTEINS; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 0031438386     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Bennett MH, MacLennan KA, Vaughan Hudson B, Vaughan Hudson G. The clinical and prognostic relevance of histopathologic classification in Hodgkin's disease. Progr Surg Pathol 1989; 10:127-51.
2. Gerdes J, Van Baarlen J, Pileri S, Schwarting R, Van Unnik JAM, Stein H. Tumor cell growth fraction in Hodgkin's disease. Am J Pathol 1987; 128:390-3.
3. Schmid C, Sweeney E, Isaacson PG. Proliferating cell nuclear antigen (PCNA) expression in Hodgkin's disease. J Pathol 1992; 168:1-6.
4. Hell K, Lorenzen J, Hansmann ML, Fellbaum C, Busch R, Fischer R. Expression of the proliferating cell nuclear antigen in the different types of Hodgkin's disease. Am J Clin Pathol 1993; 99:598-603.
5. Freeman J, Kellock DB, Yu CC, Crocker J, Levison DA, Hall PA. Proliferating cell nuclear antigen (PCNA) and nucleolar organizer regions in Hodgkin's disease: correlation with morphology. J Clin Pathol 1993; 46:446-9.
6. Benjamin DR, Gown AM. Aberrant cytoplasmic expression of proliferating cell nuclear antigen in Hodgkin's disease. Am J Surg Pathol 1991; 115:764-8.
7. Prosperi E, Stivala LA, Sala E, Scovassi AI, Bianchi L. Proliferating cell nuclear antigen complex formation induced by ultraviolet irradiation in human quiescent fibroblasts as detected by immunostaining and flow cytometry. Exp Cell Res 1993; 205:320-5.
8. Doggett RS, Colby TV, Dorfman RF. Interfollicular Hodgkin's disease. Am J Surg Pathol 1983; 7:145-9.
9. Hsu SM, Rami L, Fanger H. Use of avidin biotin peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981; 29:577-80.
10. Cordell JL, Falini B, Erber WN, et al. Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984; 32:219-29.
11. Pich A, Ponti R, Valente G, et al. MIB-1, Ki67, and PCNA scores and DNA flow cytometry in intermediate grade malignant lymphomas. J Clin Pathol 1994; 47:18-22.
12. Ferry JA, Linggood RM, Convery KM, Efird JT, Eliseo R, Harris NL. Hodgkin's disease, nodular sclerosis type. Implications of histologic subclassification. Cancer 1993; 71:457-63.
13. Hall PA, Richards MA, Gregory WM, d'Ardenne AJ, Lister TA, Stansfeld AG. The prognostic value of Ki67 immunostaining in non-Hodgkin's lymphoma. J Pathol 1988; 154:223-35.
14. Landberg G, Tan EM, Roos G. Flow cytometric multiparameter analysis of proliferating cell nuclear antigen/cyclin and Ki67 antigen: a new view of the cell cycle. Exp Cell Res 1990; 187:111-8.
15. Key G, Becker MH, Baron B, et al. New Ki-67-equivalent murine monoclonal antibodies (MIB1-3) generated bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope. Lab Invest 1993; 68:629-36.
16. Spina D, Leoncini L, Close P, et al. Growth vs. DNA strand breaks in Hodgkin's disease: impaired proliferative ability of Hodgkin and Reed-Sternberg cells. Int J Cancer 1996; 66:179-83.
17. Weiss LM, Strickler JG, Warnke RA, Purtilo DT, Sklar J. Epstein-Barr viral DNA in tissues of Hodgkin's disease. Am J Pathol 1987; 129:86-91.
18. Pallesen G, Hamilton-Dutoit SJ, Rowe M, Young LS. Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's disease. Lancet 1991; 337:320-2.
19. Herbst H, Dallenbach F, Hummel M et al. Epstein-Barr virus latent membrane protein expression in Hodgkin and Reed-Sternberg cells. Proc Natl Acad Sci USA 1991; 88:4766-70.
20. Brousset P, Chittal S, Schlaifer D et al. Detection of Epstein-Barr virus messenger RNA in Reed-Sternberg cells of Hodgkin's disease by in situ hybridization with biotinylated probes on specially processed modified acetone methyl benzoate xylene (ModAMeX) sections. Blood 1991; 77:1781-6.
21. Valente G, Negro F, Pacchioni D, Palestro G. Infection by Epstein-Barr virus in Hodgkin's disease is not restricted to the Reed-Sternberg cells. Br J Haematol 1994; 86:405-6.
22. Luppi M, Torelli G. The new lymphotropic herpesviruses (HHV-7, HHV-8) and hepatitis C virus (HCV) in human lymphoproliferative diseases: an overview. Haematologica 1996; 81:265-81.
23. Valente G, Secchiero P, Lusso P, et al. Human herpesvirus 6 and Epstein-Barr virus in Hodgkin's disease. A controlled study by polymerase chain reaction and in situ hybridization. Am J Pathol 1996; 149:1501-10.
24. Carbone A, Gloghini A, Zanette I, Canal B, Rizzo A, Volpe R. Coexpression of Epstein-Barr virus latent membrane protein and vimentin in "aggressive" histological subtypes of Hodgkin's disease. Virchow Arch A Pathol Anat Histopathol 1993; 422:39-45.
25. Ruco LP, Pomponi D, Pigott R, et al. Cytokine production (IL-1a, IL-1b, and TNFα) and endothelial cell activation (ELAM-1 and HLA-DR) in reactive lymphadenitis, Hodgkin's disease, and in non-Hodgkin's lymphomas. An immunocytochemical study. Am J Pathol 1990; 137:1163-71.
26. Tesch H, Gunther A, Abts H, et al. Expression of interleukin-2Ra and interleukin-2Rb in Hodgkin's disease. Am J Pathol 1993; 142:1714-20.
27. Strauchen JA, Breakstone BA. IL-2 receptor expression in human lymphoid lesions. Immunohistochemical study of 166 cases. Am J Pathol 1987; 126:1506-12.
28. Doussis IA, Pezzella F, Lane DP, Gatter KC, Mason DY. An immunocytochemical study of p53 and bcl-2 protein expression in Hodgkin's disease. Am J Clin Pathol 1993; 99:663-7.
29. Erdkamp FL, Breed WP, Schouten HC, et al. DNA aneuploidy and cell proliferation in relation to histology and prognosis in patients with Hodgkin's disease. Ann Oncol 1993; 4:75-80.