Platelet-derived growth factor prevents ischemia-induced neuronal injuries in vivo

Neuroscience Research

Volumn 29, Issue 4, 1997, Pages 335-343

  Kawabe, Tadao ^a   Wen, Tong Chun ^a   Matsuda, Seiji ^a   Ishihara, Ken ^b   Otsuka, Hiroki ^a   Sakanaka, Masahiro ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b OSAKA NATIONAL HOSPITAL   (Japan)

Author keywords

DNA fragmentation; Gerbil; Hippocampus; Platelet derived growth factor; Synapse; Transient forebrain ischemia

Indexed keywords

DNA FRAGMENT; NEUROPROTECTIVE AGENT; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY OCCLUSION; ARTICLE; BRAIN ISCHEMIA; BRAIN TEMPERATURE; BRAIN VENTRICLE; COMMON CAROTID ARTERY; CONTROLLED STUDY; FOREBRAIN; GERBIL; HIPPOCAMPUS; HISTOLOGY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LATENT PERIOD; MALE; NERVE CELL NECROSIS; NERVE INJURY; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SYNAPSE;

ANIMALS; BRAIN ISCHEMIA; GERBILLINAE; HIPPOCAMPUS; LEARNING; MALE; MOLECULAR PROBE TECHNIQUES; NEURONS; PLATELET-DERIVED GROWTH FACTOR; PROSENCEPHALON;

EID: 0031436571     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(97)00105-3     Document Type: Article

References (41)

1. Araki H., Nojiri M., Kawashima K., Kimura M., Aihara H. Behavioral, electroencephalographic and histopathological studies on Mongolian gerbils with occluded common carotid arteries. Physiol. Behav. 38:1986;89-94.
2. Beck T., Lindholm D., Castren E., Wree A. Brain-derived neurotrophic factor protects against ischemic cell damage in rat hippocampus. J. Cereb. Blood Flow Metab. 14:1994;689-692.
3. Cheng B., Christakos S., Mattson M.P. Tumor necrosis factors protect neurons against excitotoxic/metabolic insults and promote maintenance of calcium homeostasis. Neuron. 12:1994;139-153.
4. Cheng B., Mattson M.P. NGF and bFGF protect rat and human central neurons against hypoglycemic damage by stabilizing calcium homeostasis. Neuron. 7:1991;1031-1041.
5. Cheng B., Mattson M.P. NT-3 and BDNF protect hippocampal, septal and cortical neurons against metabolic compromise. Brain Res. 640:1994;56-67.
6. Cheng B., Mattson M.P. PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: evidence for induction of antioxidant pathways. J. Neurosci. 15:1995;7095-7104.
7. Choi D.W. Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7:1987;369-379.
8. Claesson-Welsh L., Mammacher A., Westermark B., Heldin C.H., Nister M. Identification and structural analysis of the A type receptor for platelet-derived growth factor: similarities with the B type receptor. J. Biol. Chem. 264:1988;1742-1747.
9. Giacobini, M.M., Smits, A., Funa, K., Westermark, B., Olson, L., 1992. Differential effects of platelet-derived growth factors on fetal hippocampal and cortical grafts: evidence from intraocular transplantation in rats., Neurosci. Lett. 136, 227-231.
10. Hart C.E., Forstrom J.W., Kelly J.D. et al. Two classes of PDGF receptor recognize different isoforms of PDGF. Science. 240:1988;1529-1531.
11. Heldin C.H., Backstrom G., Ostman A. et al. Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two different receptor types. EMBO J. 7:1989;1387-1393.
12. Heldin C.H., Westermark B. Platelet-derived growth factor: mechanism of action and possible in vivo function. Cell Reg. 1:1990;555-566.
13. Iihara K., Sasahara M., Hashimoto N., Uemura Y., Kikuchi H., Hazama F. Ischemia induces the expression of platelet-derived growth factor-B chain in neurons and brain macrophages in vivo. J. Cereb. Blood Flow Metab. 14:1994;818-824.
14. Iihara K., Sasahara M., Hashimoto N., Hazama F. Induction of platelet-derived growth factor-β receptor in focal ischemia of rat brain. J. Cereb. Blood Flow Metab. 16:1996;941-949.
15. Kotani Y., Matsuda S., Wen T.-C. et al. A hydrophilic peptide comprising 18 amino acid residues of the prosaposin sequence has neurotrophic activity in vitro and in vivo. J. Neurochem. 66:1996;2197-2200.
16. Krupinski J., Issa R., Bujny T., Slevin M., Kumar P., Kumar S., Kaluza J. A putative role for platelet-derived growth factor in angiogenesis and neuroprotection after ischemic stroke in humans. Stroke. 28:1997;564-573.
17. 1, a main ingredient of ginseng root. Neurosci. Res. 28:1997;191-200.
18. Matsuda S., Wen T.-C., Morita F., Otsuka H., Igase K., Yoshimura H., Sakanaka M. Interleukin-6 prevents ischemia-induced learning disability and neuronal and synaptic loss in gerbils. Neurosci. Lett. 204:1996;109-112.
19. 2 analogue, TEI-7165, on ischemic neuronal damage in gerbils. Brain Res. 769:1997;321-328.
20. Matsui T., Heidaran M., Miki T. et al. Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes. Science. 243:1989;800-804.
21. Mattson M.P., Murrain M., Guthrie P.B., Kater S.B. Fibroblast growth factor and glutamate: opposing actions in the generation and degeneration of hippocampal neuroarchitecture. J. Neurosci. 9:1989;3728-3740.
22. Mitani A., Andou Y., Masuda S., Kataoka K. Transient forebrain ischemia of three-minute duration consistently induces severe neuronal damage in field CA1 of the hippocampus in the normothermic gerbil. Neurosci. Lett. 131:1991;171-174.
23. Nikkhah G., Odin P., Smits A. et al. Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture. Exp. Brain Res. 92:1993;516-523.
24. Nitatori T., Sato N., Waguri S. et al. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J. Neurosci. 15:1995;1001-1011.
25. Pringle N.P., Mudhar H.S., Collarini E.J., Richardson W.D. PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage. Development. 115:1992;535-551.
26. Ross R., Raines E.W., Bowen-Pope D.F. The biology of platelet-derived growth factor. Cell. 46:1986;155-169.
27. Sano A., Matsuda S., Wen T.-C. et al. Protection by prosaposin against ischemia-induced learning disability and neuronal loss. Biochem. Biophys. Res. Comm. 204:1994;994-1000.
28. Sasahara A., Kott J.N., Sasahara M., Raines E.W., Gown A.M., Westrum L.E. Platelet-derived growth factor-B chain-like immunoreactivity in the developing and adult rat brain. Dev. Brain Res. 68:1992;41-53.
29. Sasahara M., Fries J.W.U., Raines E.W. et al. PDGF-B chain in neurons of central nervous system, posterior pituitary and in a transgenic model. Cell. 64:1991;217-227.
30. Seifert R.A., hart C.E., Philips P.E., Forstrom J.W., Ross R., Murray M., Bowen-Pope D.F. Two different subunits associate to create isoform-specific platelet-derived growth factor receptors. J. Biol. Chem. 264:1989;8771-8778.
31. Smits A., Hermansson M., Nister M., Karnushina I., heldin C.-H., Westermark B., Funa K. Rat brain capillary endothelial cells express functional PDGF B-type receptors. Growth Factors. 2:1989;1-8.
32. Smits A., Kato M., Westermark B., Nister M., heldin C.-H., Funa K. Neurotrophic activity of platelet-derived growth factor (PDGF): rat neuronal cells possess functional PDGF β-type receptors and respond to PDGF. Proc. Natl. Acad. Sci. USA. 88:1991;8159-8163.
33. Takayama S., Sasahara M., Iihara K., Handa J., Hazama P. Platelet-derived growth factor B-chain-like immunoreactivity in injured rat brain. Brain Res. 653:1994;131-140.
34. Thiessen D., Yahr P. The gerbil in behavioral investigations, mechanisms of territoriality and olfactory communication. A stereo-taxic brain atlas of the gerbil. 1977;138 University of Texas, Texas.
35. Valenzuela C.F., Xiong Z., MacDonald J.F., Weiner J.L., Frazier C.J., Dunwiddie T.V., Kazlauskas A., Whiting P.J., Harris R.A. Platelet-derived growth factor induces a long-term inhibition of N-methyl-D-aspartate receptor function. J. Biol. Chem. 271:1996;16151-16159.
36. Wen T.-C., Matsuda S., Yoshimura H., Aburaya J., Kushihata F., Sakanaka M. Protective effect of basic fibroblast growth factor-heparin and neurotoxic effect of platelet factor 4 on ischemic neuronal loss and learning disability in gerbils. Neuroscience. 65:1995a;513-521.
37. Wen T.-C., Matsuda S., Yoshimura H., Kawabe T., Sakanaka M. Ciliary neurotrophic factor prevents ischemia-induced learning disability and neuronal loss in gerbils. Neurosci. Lett. 191:1995b;55-58.
38. Wen T.-C., Yoshimura H., Matsuda S., Lim J.-H., Sakanaka M. Ginseng root prevents learning disability and neuronal loss in gerbils with 5 minute forebrain ischemia. Acta Neuropathol. 91:1996;15-22.
39. Williams L.T. Signal transduction by the platelet-derived growth factor receptor. Science. 243:1989;1564-1570.
40. Yeh H.J., silos-Santiago I., Wang Y.X., George R.J., Snider W.D., Deuel T.F. Developmental expression of the platelet-derived growth factor alpha-receptor gene in mammalian central nervous system. Proc. Natl. Acad. Sci. USA. 90:1993;1952-1956.
41. Zhang Y., Tatsuno T., Carney J., Mattson M.P. Basic FGF, NGF and IGFs protect hippocampal neurons against iron-induced degeneration. J. Cereb. Blood Flow Metab. 13:1993;378-388.