Characterization of [3H]-N-[R-(2-benzothiazolyl)thio-2-propyl]-2-chloroadenosine ([3H]-NNC 21-0136) binding to rat brain: Profile of a novel selective agonist for adenosine A1 receptors

Drug Development Research

Volumn 42, Issue 2, 1997, Pages 86-97

  Thomsen, Christian ^a   Valsborg, Jacob S ^a   Foged, Christian ^a   Knutsen, Lars ^a,b  

^a NOVO NORDISK A S   (Denmark)

^b Cerebrus Limited   (United Kingdom)

Author keywords

(NNC 21 0136); Adenosine receptors; Autoradiography; Ischemia; N R (2 benzothiazolyl)thio 2 propyl 2 chloroadenosine; Novel adenosine A1 agonist

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2 CHLORO 6 N CYCLOPENTYLADENOSINE; 2 CHLOROADENOSINE; 6 N CYCLOHEXYL 2' O METHYLADENOSINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; 9 CHLORO 2 (2 FURYL) 5,6 DIHYDRO 5 IMINO 1,2,4 TRIAZOLO[2,3 C]QUINAZOLINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ADENOSINE RECEPTOR STIMULATING AGENT; N [(2 BENZOTHIAZOLYL)THIO 2 PROPYL] 2 CHLOROADENOSINE; RECEPTOR SUBTYPE; THEOPHYLLINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN REGION; BRAIN TISSUE; CEREBELLUM CORTEX; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NONHUMAN; RAT; RECEPTOR AFFINITY;

EID: 0031432945     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199710)42:2<86::AID-DDR5>3.0.CO;2-L     Document Type: Article

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