Refractory depression in children and adolescents

Depression and Anxiety

Volumn 5, Issue 4, 1997, Pages 212-223

  Botteron, Kelly N ^a,b,c   Geller, Barbara ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE   (United States)

Author keywords

Affective disorder; Antidepressive agents; Genetics; Growth and development; Neuroimaging brain; Psychotherapy; Social adjustment

Indexed keywords

AMITRIPTYLINE; DESIPRAMINE; FLUOXETINE; IMIPRAMINE; LITHIUM; MONOAMINE OXIDASE INHIBITOR; NEFAZODONE; NORTRIPTYLINE; PLACEBO; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE;

ADOLESCENT; AFFECTIVE NEUROSIS; ATTENTION DEFICIT DISORDER; CHILD; CHILD PSYCHIATRY; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; DEPRESSION; ELECTROCONVULSIVE THERAPY; ENVIRONMENTAL FACTOR; FAMILY STUDY; GENETICS; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PSYCHOSOCIAL ENVIRONMENT; PSYCHOTHERAPY; REVIEW; SUBSTANCE ABUSE; TREATMENT FAILURE;

ADOLESCENT; ADULT; ANTIDEPRESSIVE AGENTS; BRAIN; CASE MANAGEMENT; CHILD; CHILD PSYCHIATRY; CONTROLLED CLINICAL TRIALS; DEPRESSIVE DISORDER; DRUG RESISTANCE; FAMILY HEALTH; HUMANS; PERSONALITY DEVELOPMENT; PSYCHOTHERAPY; SOCIAL ADJUSTMENT;

EID: 0031431875     PISSN: 10914269     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6394(1997)5:4<212::AID-DA7>3.0.CO;2-E     Document Type: Review

References (82)

1. Anderson C, Hammen C (1993) Psychosocial outcomes of children of unipolar depressed, bipolar medically ill and normal women: A longitudinal study. J Consult Clin Psychol 61:448-454.
2. Andreasen N, Endicott J, Spitzer R, Winokur G (1977) The family history method using diagnostic criteria: Reliability and validity. Arch Gen Psychiatry 34:1229-1235.
3. Barnett P, Gotlib I (1988) Psychosocial functioning and depression: Distinguishing among antecedents, concomitants and consequences. Psychol Bull 104:97-126.
4. Barrickman LL, Perry PJ, Allen AJ, Kuperman S, Arndt SV, Herrmann KJ, Schumacher E (1995) Bupropion versus methylphenidate in the treatment of attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 34:649-657.
5. Billings AG, Moos RH (1985) Life Stressors and social resources effect posttretment outcomes among depressed patients. J Abnorm Psychol 94:140-153.
6. Birmaher B, Ryan ND, Williamson DE, Brent DA, Kaufman J, Dahl RE, Perel J, Nelson B (1996a) Childhood and adolescent depression: A review of the past 10 years. Part I. J Am Acad Child Adolesc Psychiatry 35:1427-1439.
7. Birmaher R, Ryan ND, Williamson DE, Brent DA, Kaufman J (1996b) Childhood and adolescent depression: A review of the past 10 years. Part II. J Am Acad Child Adolesc Psychiatry 35:1575-1583.
8. Botteron KN, Figiel GS (1997) The neuromorphometry of affective disorders. In Krishnan KRR, Doraiswamy M (eds): Brain Imaging in Clinical Psychiatry. New York: Marcel Dekker Press, pp 145-184.
9. Botteron KN, Vannier MW, Geller B, Todd R, Lee BC (1995a) Magnetic resonance imaging in childhood and adolescent bipolar affective disorder: A pilot investigation. J Am Acad Child Adolesc Psychiatry 34:742-749.
10. Botteron KN, Geller B, Vannier MW (1995b) Prefrontal lobe volume in prepubertal major depression. Presented at the American Academy of Child and Adolescent Psychiatry Annual Meeting, New York.
11. Brent DA, Roth C, Holder D, Kolko DJ, Birmaher B, Johnson BA, Schweers JA (1997) Adolescent depression: A comparison of three psychosocial interventions. In Hibbs ED, Jensen PS (eds): Psychosocial Treatment for Child and Adolescent Disorders: Empirically Based Approaches. Washington, DC: American Psychological Association Press.
12. Campbell M, Kafantaris V, Cueva JE (1995) An update on the use of lithium carbonate in aggressive children and adolescents with conduct disorder. Psychopharmacol Bull 31:93-102.
13. Coffey CE, Figiel GS, Djang WT, Saunders WB, Weiner RD (1989) White matter hyperintensity on magnetic resonance imaging: Clinical and neuroanatomic correlates in the depressed elderly. J Neuropsychiatry Clin Neruosci 1:135-144.
14. Coffey CE, Wilkinson WE, Weiner RD, Parashos IA, Djang WT, Webb MC, Figiel GS, Spritzer CE (1993) Quantitative cerebral anatomy in depression. Arch Gen Psychiatry 50:7-16.
15. Cummings JL (1993) Frontal-subcortical circuits and human behavior. Arch Neurol 50:873-880.
16. Drevets WC, Botteron K (1996) Neuroimaging in Psychiatry. In Guze S (ed): Washington University Adult Psychiatry. St. Louis: Mosby Year Book pp 53-81.
17. Drevets WC, Videen TO, Price JL, Preskorn SH, Carmichael ST, Raichle ME (1992) A functional anatomical study of unipolar depression. J Neurosci 12:3628-3641.
18. Dupont RM, Jernigan TL, Butters N, Delis D, Hesselink JR, Heindel W, Gillin JC (1990) Subcortical abnormalities detected in bipolar affective disorder using magnetic resonance imaging. Arch Gen Psychiatry 47:55-59.
19. Emslic G, Rush AJ, Weinberg AW (1997) A double-blind, randomized placebo-controlled trial of fluoxetine in depressed children and adolescents. Arch Gen Psychiatry 000:000-000.
20. Fava M, Davidson KG (1996) Definition and epidemiology of treatment-resistant depression. Psychiatric Clin N Am 19:179-200.
21. Figiel GS, Krishnan KRR, Rao VP, Doraiswamy M, Ellinwood EH, Nemeroff CB, Evans D, Boyko O (1991) Subcortical hyperintensities on brain magnetic resonance imaging: A comparison of normal and bipolar subjects. J Neuropsychiatry 3:18-22.
22. Geller B (1996) The high prevalence of bipolar parents among prepubertal mood-disordered children necessitates appropriate questions to establish bipolarity. Curr Opin Psychiatry 9:239-240.
23. Geller B (1997) Treatment of major depressive disorders. Presented at the Annual Mid-Year Institute of the American Academy of Child and Adolescent Psychiatry, March 19-21, 1997, Hamilton, Bermuda.
24. Geller B, Cooper T, McCombs H, Graham D, Wells J (1989) Double-blind, placebo-controlled study of nortriptyline in depressed children using a "fixed plasma level" design. Psychopharmacol Bull 25:101-108.
25. Geller B, Cooper T, Graham D, Marsteller F, Bryand D (1990) Double-blind placebo-controlled study of nortriptyline in depressed adolescents using a "fixed plasma level" design. Psychopharmacol Bull 26:85-90.
26. Geller B, Cooper TB, Graham D, Fetner HH, Wells J (1992) Pharmacokinetically designed double-blind placebo-controlled study of nortriptyline in 6- to 12-year-olds with major depressive disorder. J Am Acad Child Adolesc Psychiatry 31:34-44.
27. Geller B, Fox LW, Clark KA (1994) Rate and predictors of prepubertal bipolarity during follow-up of 6- to 12-year-old depressed children. J Am Acad Child Adolesc Psychiatry 33: 461-468.
28. Giedd JN, Snell JW, Lange N, Rajapakse JC, Casey BJ, Kozuch P, Vaituzis AC, Vauss YC, Kaysen D, Hamburger SD, Rapoport JL (1996) Quantitative magnetic resonance imaging of human brain development: Ages 4-18. Cerebral Cortex 6:551-560.
29. Hammen C, Gordon D, Burge D, Adrian C, Jaenicke C, Hiroto D (1987) Maternal affective disorders, illness, and stress: Risk for children's psychopathology. Am J Psychiatry 144:736-741.
30. Hughes CW, Preskorn S, Weller E, Weller R, Hassanein R, Tucker S (1990a) The effect of concomitant disorders in childhood depression on predicting treatment response. Psychopharmacol Bull 26:235-238.
31. Hughes CW, Preskorn SH, Wrona M, Hassanein R, Tucker S (1990b) Follow-up of adolescents initially treated for prepubertal-onset major depressive disorder with imipramine. Psychopharmacol Bull 26:244-248.
32. Jernigan TL, Trauner DA, Hesselink JR, Tallal PA (1991) Maturation of human cerebrum observed in vivo during adolescence. Brain 114:2037-2049.
33. Kahn JS, Kehle TJ, Jenson WR, Clark E (1990) Comparison of cognitive-behavioral relaxation and self-modeling interventions for depression among middle-school students. School Psychology-Review 19:196-211.
34. Kashani J, Shekim W, Reid J (1984) Amitriptyline in children with major depressive disorder: A double-blind crossover pilot study. J Am Acad Child Adolesc Psychiatry 348-351.
35. Kaslow NJ, Tanebaum RL, Abramson LY, Peterson C, Seligman MEP (1983) Problem-solving deficits and depressive symptoms among children. Abnorm Child Psychol 11:497-502.
36. Kendall P, Kortlander E, Chansky T, Brady E (1992) Comorbidity of anxiety and depression in youth: Treatment implications. J Consult Clin Psychol 60:869-880.
37. Kennedy E, Spence S, Hensley R (1989) An examination of the relationship between childhood depression and social competence amongst primary school children. J Child Psychol Psychiatry 30:561-573.
38. Klein RG, Koplewicz HS, Kanner A (1992) Imipramine treatment of children with separation anxiety disorder. J Am Acad Child Adolesc Psychiatry 31:21-28.
39. Klerman G, Weissman M (1993) New Applications of Interpersonal Psychotherapy. Washington, DC: American Psychiatric Press.
40. Kovacs M, Feinberg TL, Crouse-Novak M, Paulauskas SL, Pollock M, Finkelstein R (1984a) Depressive disorders in childhood, II. A longitudinal study of the risk for a subsequent major depression. Arch Gen Psychiatry 41:643-649.
41. Kovacs M, Feinberg TL, Crouse-Novak MA, Paulauskas SL, Finkelstein R (1984b) Depressive disorders in childhood, I. A longitudinal prospective study of characteristics and recovery. Arch Gen Psychiatry 41:229-237.
42. Kramer A, Feiguine R (1981) Clinical effects of amitriptyline in adolescent depression: A pilot study. J Am Acad Child Psychiatry 20:636-644.
43. Kupfer D, Frank E, Perel J, Corres C, Mallinger AG, Thase ME, McEachran AB, Grochinski VJ (1992) Five-year outcome for maintenance therapies in recurrent depression. Arch Gen Psychiatry 49:769-773.
44. Kutcher S, Boulos C, Ward B, Marton P, Simeon J, Ferguson HB, Szalai J, Katic M, Roberts N, Dubois C (1994) Response to desipramine treatment in adolescent depression: A fixed dose, placebo-controlled trial. J Am Acad Child Adolesc Psychiatry 686-694.
45. Kye CH, Waterman GS, Ryan ND, Birmaher B, Williamson DE, Iyengar S, Dachille S (1996) A randomized, controlled trial of amitriptyline in the acute treatment of adolescent major depression. J Am Acad Child Adolesc Psychiatry 1139-1144.
46. Lewinsohn PM, Clarke GN, Seeley JR, Rohde P (1994) Major depression in community adolescents: Age at onset, episode duration, and time to recurrence. J Am Acad Child Adolesc Psychiatry 33:809-818.
47. McCauley E, Myers K, Mitchel J, Calcron R, Schloredt K, Treder R (1993) Depression in young people: Initial presentation and clinical course. J Am Acad Child Adolesc Psychiatry 32:714-722.
48. McGee R, Williams S (1988) A longitudinal study of depression in nine-year-old children. J Am Acad Child Adolesc Psychiatry 27:342-348.
49. Miller L, Barrett C, Hampe E, Nobel H (1972) Comparison of reciprocal inhibition, psychotherapy and waiting list control for phobic children. J Abnorm Psychol 79:269-279.
50. Mufson L, Moreau D, Weissman M, Wickramaratne P, Martin J, Samoilov A (1994) Modification of interpersonal psychotherapy with depressed adolescents (IPT-A): Phase I and II studies. J Am Acad Child Adolesc Psychiatry 33:695-705.
51. Murrin L, Gibbens D, Ferrer J (1985) Ontogeny of dopamine, serotonin, and spirocecanone receptors in rat forebrain: An autoradiographic study. Dev Brain Res 23:91-109.
52. Nordberg A (1986) The aging of cholinergic synapses: Ontogenesis of cholinergic receptors. In Hannin I (ed): Dynamics of Cholinergic Function. New York: Plenum Press, pp 165-175.
53. Orvaschel H, Walsh-Allis G, Ye W (1988) Psychopathology in children of parents with recurrent depression. J Abnorm Child Psychol 16:17-28.
54. Petti T, Law W (1982) Imipramine treatment of depressed children: A double-blind pilot study. J Clin Psychopharmacol 107-110.
55. Pike A, Plomin R (1996) Importance of nonshared environmental factors for childhood and adolescent psychopathology. J Am Acad Child Adolesc Psychiatry 35:560-570.
56. Preskorn SH, Weller EB, Hughes CW, Weller RA, Bolte K (1987) Depression in prepubertal children: Dexamethasone nonsuppression predicts differential response to imipramine vs placebo. Psychopharmacol Bull 450-453.
57. Puig-Antich J, Luken E, Davies M, Goetz D, Brennan-Quattrok J, Todak G (1985a) Psychosocial functioning in prepubertal major depressive disorders: I. Arch Gen Psychiatry 42:500-507.
58. Puig-Antich J, Luken E, Davies M, Goetz D, Brennan-Quattrok J, Todak G (1985b) Psychosocial functioning in prepubertal major depressive disorders: II. Arch Gen Psychiatry 42:511-517.
59. Puig-Antich J, Perel J, Lupakin W, Chambers W, Tabrizi M, King J, Goetz R, Davie M, Stiller R (1987) Imipramine in prepubertal major depressive disorders. Arch Gen Psychiatry 44:81-89.
60. Puig-Antich J, Goetz D, Davies M, Kaplan T, Davies S, Ostrow L, Asnis L, Twomey J, Iyengar S, Ryan ND (1989) A controlled family history study of prepubertal major depressive disorder. Arch Gen Psychiatry 46:406-418.
61. Rao U, Weissman M, Martin J, Hammond RW (1993) Childhood depression and risk of suicide: A preliminary report of a longitudinal study. J Am Acad Child Adolesc Psychiatry 32:21-27.
62. Rao U, Ryan ND, Birmaher B, Dahl RE, Williamson DE, Kaufman J, Rao R, Nelson B (1995) Unipolar depression in adolescents: Clinical outcome in adulthood. J Am Acad Child Adolesc Psychiatry 34:566-578.
63. Reynolds WM, Coates KI (1986) A comparison of cognitive-behavioral therapy and relaxation training for the treatment of depression in adolescents. J of Consulting and Clinical Psychology 54:658-660.
64. Riddle MA, Geller B, Ryan N (1993) Another sudden death in a child treated with desipramine. J Am Acad Child Adolesc Psychiatry 143:1283-1286.
65. Robbins D, Alessi N, Colfer M (1989) Treatment of adolescents with major depression: Implications of the DST and the melancholic clinical subtype. J Affect Disord 17:99-104.
66. Sanford M, Szatmari P, Spinner M, Munroe-Blum H, Jamieson E, Walsh C, Jones D (1995) Predicting the one-year course of adolescent major depression. J Am Acad Child Adolcsc Psychiatry 34:1618-1628.
67. Sargeant J, Bruce M, Florio L, Weissman M (1990) Factors associated with 1-year outcome of major depression in the community. Arch Gen Psychiatry 47:519-526.
68. Simeon JG, Dinicola VF, Ferguson HB, Copping W (1990) Adolescent depression: A placebo-controlled fluoxetine treatment study and follow-up. Prog Neurol/Psychopharmacol Biol Psychiatry 14:791-795.
69. Stark K, Reynolds W, Kaslow N (1987) A comparison of the relative efficacy of self-control therapy and a behavioral problem-solving therapy for depression in children. J Abnorm Child Psychol 15:91-113.
70. Steingard RJ, Renshaw PF, Yurgelun-Todd D, Appelmans K, Lyoo K, Shorrock KL, Bucci JP, Cesena M, Abebe D, Zurakowski D, Poussaint TY, Barnes P (1996) Structural abnormalities in brain magnetic resonance images of depressed children. J Am Acad Child Adolesc Psychiatry 35:307-311.
71. Strober M, Lampert C, Schmidt S, Morrell W (1993) The course of major depressive disorder in adolescents: I. Recovery and risk of manic switching in a follow-up of psychotic and nonpsychotic subtypes. J Am Acad Child Adolesc Psychiatry 32:34-42.
72. Swayze VW, Andreasen NC, Alliger RJ, Ehrhardt JC, Yuh WT (1990) Structural brain abnormalities in bipolar affective disorder. Arch Gen Psychiatry 47:1057-1059.
73. Swerdlow NR, Koob GF (1987) Dopamine, schizophrenia, mania and depression: Toward a unified hypothesis of cortico-stiato-pallido-thalamic function. Bchav Brain Sci 10:197-245.
74. Swindle R, Cronkite R, Moos R (1989) Life Stressors, social resources, coping, and the 4-year course of unipolar depression. J Abnorm Psychol 98:468-477.
75. Szapocznik J, Rio A, Murray E, Cohen R, Scopetta M, Rivas-Vazquez, A, Hervis O, Posada V, Kurtines W (1989) Structural family versus psychodynamic child therapy for problematic Hispanic boys. J Consult Clin Psychol 571-578.
76. Thurber S, Ensign J, Punnett A, Welter K (1995) A Meta-analysis of antidepressant outcome studies that involved children and adolescents. J Clin Psychol 51:340-345.
77. Todd RD, Neuman R, Geller B, Fox LW, Hickock J (1993) Genetic studies of affective disorders: Should we be starting with childhood onset probands? J Am Acad Child Adolesc Psychiatry 32:1164-1171.
78. Todd RD, Geller B, Neuman R, Fox LW, Hickock J (1996) In-creased prevalence of alcoholism in relatives of depressed bipolar children. J Am Acad Child Adolesc Psychiatry 35: 716-723.
79. Walter G, Rey JM (1997) An epidemiological study of the use of ECT in adolescents. J Am Acad Child Adolesc Psychiatry 36:809-815.
80. Warner V, Weissman M, Fendrich M, Wickramaratne P, Moreau D (1992) The course of major depression in the offspring of depressed parents. Arch Gen Psychiatry 49:795-801.
81. Weissman M, Gammon G, John K, Merikangas K, Warner V, Prusoff B, Sholomskas D (1987) Children of depressed parents. Arch Gen Psychiatry 44:847-853.
82. Weller R, Kapadia P, Weller E, Fristad M, Lazaroff L, Preskorn S (1994) Psychopathology in families of children with major de-pressive disorders. J Affect Disord 31:247-252.