Alternative approaches to refractory depression in bipolar illness

Depression and Anxiety

Volumn 5, Issue 4, 1997, Pages 175-189

  Post, Robert M ^a   Leverich, Gabriele S ^a   Denicoff, Kirk D ^a   Frye, Mark A ^a   Kimbrell, Tim A ^a   Dunn, Robert ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Antidepressants; Bipolar illness; Refractory depression

Indexed keywords

AMFEBUTAMONE; ANTICONVULSIVE AGENT; ASCORBIC ACID; BROMOCRIPTINE; CALCIUM CHANNEL BLOCKING AGENT; CARBAMAZEPINE; CHOLINE; DIHYDROPYRIDINE DERIVATIVE; DILTIAZEM; FLUNARIZINE; FOLIC ACID; GABAPENTIN; INOSITOL; ISRADIPINE; LAMOTRIGINE; LIOTHYRONINE; LITHIUM; MELATONIN; MONOAMINE OXIDASE INHIBITOR; NIFEDIPINE; NIMODIPINE; OXCARBAZEPINE; PLACEBO; PSYCHOSTIMULANT AGENT; RISPERIDONE; THYROXINE; UNINDEXED DRUG; VALPROATE SEMISODIUM; VALPROIC ACID; VERAPAMIL;

ARTICLE; CLINICAL TRIAL; DEPRESSION; DRUG RESPONSE; ELECTROCONVULSIVE THERAPY; HUMAN; MANIC DEPRESSIVE PSYCHOSIS; PRIORITY JOURNAL; TREATMENT FAILURE;

EID: 0031428334     PISSN: 10914269     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6394(1997)5:4<175::AID-DA4>3.0.CO;2-C     Document Type: Article

References (180)

1. Ahlfors UG, Baastrup PC, Dencker SJ, Eigen K, Lingjaerde O, Pedersen V, Schou M, Aaskoven O (1981) Flupenthixol decanoate in recurrent manic depressive illness. A comparison with lithium. Acta Psychiatr Scand 64:226-237.
2. Albright PS, Burnham WM (1980) Development of a new pharmacological seizure model: Effects of anticonvulsants on corticaland amygdala-kindled seizures in the rat. Epilepsia 21: 681-689.
3. Ali SO, Denicoff KD, Ketter TA, Smith-Jackson EE, Post RM (1997) Psychosensory symptoms in bipolar disorder. Neuropsychiatry Neuropsychol Beliav Neurol (in press).
4. Altshuler LL, Post RM, Leverich GS, Mikalauskas K, Rosoff A, Ackerman L (1995) Antidepressant-induced mania and cycle acceleration: A controversy revisited. Am J Psychiatry 152:1130-1138.
5. Arap Mengech HN (1985) Carbamazepine in manic depressive psychosis. East Afr Med J 62:172-174.
6. Balfour JA, Bryson HM (1994) Valproic acid: A review of its pharmacology and therapeutic potential in indications other than epilepsy. CNS Drugs 2:144-173.
7. Ballenger JC, Post RM (1978) Therapeutic effects of carbamazepine in affective illness: Preliminary report. Commun Psychopharmacol 2:159-175.
8. Barker WA, Eccleston D (1984) The treatment of chronic depression. An illustrative case. Br J Psychiatry 144:317-319.
9. Barrickman LL, Perry PJ, Allen AJ, Kuperman S, Arndt SV, Herrmann KJ, Schumacher E (1995) Bupropion versus methylphenidate in the treatment of attention-deficit disorder. J Am Acad Child Adolesc Psychiatry 34:649-657.
10. Barton BM, Gitlin MJ (1987) Verapamil in treatment-resistant mania: An open trial. J Clin Psychopharmacol 7:101-103.
11. Bauer M, Hellweg R, Baumgartner A (1996) Adjunctive treatment with high-dose thyroxine in refractory depression (abstract). APA New Research Program and Abstracts (abstract NR330):156.
12. Baumgartner A, Bauer M, Hellweg R (1994) Treatment of intractable non-rapid cycling bipolar affective disorder with high-dose thyroxine: An open clinical trial. Neuropsychopharmacology 10:183-189
13. Bellaire W, Demisch K, Stoll K-D (1990) Carbamazepine vs. lithium. Application in the prophylaxis of recurrent affective and schizoaffective psychoses. Munch Med Wschr 132:S82-S86.
14. Benjamin J, Agam G, Levine J, Bersudsky Y, Kofman O, Belmaker RH (1995) Inositol treatment in psychiatry. Psychopharmacol Bull 31.167-175.
15. Beydoun A, Uthman BM, Sackellares JC (1995) Gabapentin: Pharmacokinetics, efficacy, and safety. Clin Neuropharmacol 18: 469-481.
16. Bowden CL (1996) Maintenance strategies for bipolar disorder. Abstracts of the 149th Annual Meeting of the American Psychiatric Association (abstract 17E):301.
17. Bowden CL, Brugger AM, Swann AC, Calabrese JR, Janicak PG, Petty F, Dilsaver SC, Davis JM, Rush AJ, Small JG, Garza-Trevino ES, Risch SC, Goodnick PJ, Morris DD (1994) Efficacy of divalproex vs. lithium and placebo in the treatment of mania. JAMA 271:918-924.
18. Brodie MJ, Richens A, Yuen AW (1995) Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. UK Lamotrigine/Carbamazepine Monotherapy Trial Group. Lancet 345:476-479.
19. Brotman AW, Farhadi AM, Gelenberg AJ (1986) Verapamil treatment of acute mania. J Clin Psychiatry 47:136-138.
20. Brunet G, Cerlich B, Robert P, Dumas S, Souetre E, Darcourt G (1990) Open trial of a calcium antagonist, nimodipine in acute mania. Clin Neuropharmacol 13:224-228.
21. Cabrera JF, Muhlbauer HD, Schley J, Stoll KD, Muller-Oerlinghausen B (1986) Long-term randomized clinical trial on oxcarbazepine vs. lithium in bipolar and schizoaffective disorders: Preliminary results. Pharmacopsychiatry 19:282-283.
22. Gaillard V (1985) Treatment of mania using a calcium antagonist: Preliminary trial. Neuropsychobiology 14:23-26.
23. Calabrese C (1996) Lamotrigine in treatment refractory manic depression. J Eur Coll Neuropsychopharmacol 6(Suppl 3):98.
24. Calabrese JR, Delucchi GA (1990) Spectrum of efficacy of valproate in 55 patients with rapid-cycling bipolar disorder. Am J Psychiatry 147:431-434.
25. Calabrese JR, Markovitz PJ, Kimmel SE, Wagner SC (1992) Spectrum of efficacy of valproate in 78 rapid-cycling bipolar patients. J Clin Psychopharmacol 12:53S-56S.
26. Calabrese JR, Woyshville MJ, Kimmel SE, Rapport DJ (1993) Predictors of valproate response in bipolar rapid cycling. J Clin Psychopharmacol 13:280-283.
27. Calabrese JR, Woyshville MJ, Rapport RT (1994) Clinical efficacy of valproate. In Joffe RT, Calabrese JR (eds): Anticonvulsants in Mood Disorders. New York: Marcel Dekker, Inc., pp 131-146.
28. Calabrese JR, Kimmel SE, Woyshville MJ, Rapport DJ, Faust CJ, Thompson PA, Meltzer HY (1996) Clozapine for treatment-refractory mania. AmJ Psychiatry 153:759-764.
29. Chen Y-W, Dilsaver SC (1996) Lifetime rates of suicide attempts among subjects with bipolar and unipolar disorders relative to subjects with other axis I disorders. Biol Psychiatry 39:896-899.
30. Colonna L, Petit M, Lepine JP (1979) Bromocriptine in affective disorders. A pilot study. J Affect Disord 1:173-177.
31. Coppen A, Chaudhry S, Swade C (1986) Folic acid enhances lithium prophylaxis. J Affect Disord 10:9-13.
32. Coxhead N, Silverstone T, Cookson J (1992) Carbamazepine versus lithium in the prophylaxis of bipolar affective disorder. Acta Psychiatr Scand 85:114-118.
33. Cullen M, Mitchell P, Brodaty H, Boyce P, Parker G, Hickie I, Wilhelm K (1991) Carbamazepine for treatment-resistant melancholia. J Clin Psychiatry 52:472-476.
34. Davies JA (1995) Mechanisms of action of antiepileptic drugs. Seizure 4:267-271.
35. Deicken RF (1990) Verapamil treatment of bipolar depression [letter]. J Clin Psychopharmacol 10:148-149.
36. Denicoff KD, Blake KD, Smith-Jackson EE, Jacob PA, Leverich GS, Post RM (1994) Morbidity in treated bipolar disorder: a one year prospective study using daily life chart ratings. Depression 2:95-104.
37. Denicoff KD, Smith-Jackson EE, Bryan AL, Ali SO, Post RM (1997a) Valproate prophylaxis in a prospective clinical trial of refractory bipolar disorder. Am J Psychiatry (in press).
38. Denicoff KD, Smith-Jackson EE, Disney ER, Ali SO, Leverich GS, Post RM (1997b) Comparative prophylactic efficacy of lithium, carbamazepine, and the combination in bipolar disorder. J Clin Psychiatry, in press.
39. Di Costanzo E, Schifano F (1991) Lithium alone or in combination with carbamazepine for the treatment of rapid-cycling bipolar affective disorder. Acta Psychiatr Scand 83:456-459.
40. Dilsaver SC, Swann SC, Chen YW, Shoaib A, Joe B, Krajewski KJ, Gruber N, Tsai Y (1996) Treatment of bipolar depression with carbamazepine: results of an open study. Biol Psychiatry 40:935-937.
41. Dimond KR, Pande AC, Lamoreaux L, Pierce MW (1996) Effect of gabapentin (Neurotonin) on mood and well-being in patients with epilepsy. Proc Neuropsychopharmacol Biol Psychiatry 20:407-417.
42. Dose M, Emrich HM, Cording-Tommel C, Von Zerssen D (1986) Use of calcium antagonists in mania. Psychoneuroendocrinology 11:241-243.
43. Dubovsky SL (1995) Calcium channel antagonists as novel agents for manic-depressive disorder. In Schatzberg AF, Nemeroff CB (eds): Textbook of Psychopharmacology. Washington, DC: American Psychiatric Press, pp 377-388.
44. Dubovsky SL, Franks RD (1983) Intracellular calcium in affective disorders: A review and an hypothesis. Biol Psychiatry 18:781-797.
45. Dubovsky SL, Franks RD (1987) Verapamil: A new antimanic drug with potential interactions with lithium. J Clin Psychiatry 48:371-372.
46. Dubovsky SL, Franks RD, Lifschitz M, Coen P (1982) Effectiveness of verapamil in the treatment of a manic patient. Am J Psychiatry 139:502-504.
47. Dubovsky S, Franks R, Schrier D (1985) Phenelzine-induced hypomania: Effect of verapamil. Biol Psychiatry 20:1009-1014.
48. Dubovsky SL, Franks RD, Allen S (1986) Calcium antagonists in mania: A double-blind study of verapamil. Psychiatry Res 18:309-320.
49. Eccieston D, Cole AJ (1990) Calcium-channel blockade and depressive illness [see comments]. Br J Psychiatry 156:889-891.
50. Eckmann F (1985a) Clinical studies on nimodipine in the treatment of patients with depressive syndromes in the second half of life. In Betz E, Deck K, Hoffmeister F (eds): Nimodipine: Pharmacological and Clinical Studies. Stuttgart: Schattauer, pp 307-313.
51. Eckmann VF (1985b) [Double-blind clinical study with the calcium antagonist flunarizine in cerebral circulatory disturbances]. Arzneimittelforschung 35:1276-1279.
52. Eikmeier G, Berger M, Lodemann E, Muszynski K, Kaumeier S, Gastpar M (1991) Trimipramine: An atypical neuroleptic? Int Clin Psychopharmacol 6:147-153.
53. Elphick M, Lyons F, Cowen PJ (1988) Low tolerability of carbamazepine in psychiatric patients may restrict its clinical usefulness. J Psychopharmacol 2:1-4.
54. Emrich HM, Dose M, Von Zerssen D (1984) Action of sodium-valproate and of oxcarbazepine in patients with affective disorders. In Emrich HM, Okuma T, Muller AA (eds): Anticonvulsants in Affective Disorders. Amsterdam: Excerpta Medica, pp 45-55.
55. Emrich HM, Dose M, Von Zerssen D (1985) The use of sodium valproate, carbamazepine and oxcarbazepine in patients with affective disorders. J Affect Disord 8:243-250.
56. Faedda GL, Baldessarini RJ, Tohen M, Strakowski SM, Waternaux C (1991) Episode sequence in bipolar disorder and response to lithium treatment. Am J Psychiatry 148:1237-1239.
57. Fawcett J, Kravitz HM, Zajecka JM, Schaff MR (1993) CNS stimulant potentiation of monoamine oxidase inhibitors in treatment-refractory depression. J Clin Psychopharmacol 11:127-132.
58. Feighner JP, Herbstein J, Damlouji N (1985) Combined MAOI, TCA, and direct stimulant therapy of treatment-resistant depression. J Clin Psychiatry 46:206-209.
59. Fitton A, Goa KL (1995) Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy. Drugs 50:691-713.
60. Folks DG, King LD, Dowdy SB (1982) Carbamazepine treatment of selected affectively disordered inpatients. Am J Psychiatry 139:115-117.
61. Foster HG, Hillbrand M, Chi CC (1989) Efficacy of carbamazepine in assaultive patients with frontal lobe dysfunction. Prog Neuropsychopharmacol Biol Psych 13:865-874.
62. Frye MA (1996) The increasing use of polypharmacy for refractory mood disorders: twenty-five years of study (abstract). APA New Research Program and Abstracts (abstract NR312).151-152.
63. Frye MA, Altshuler LL, Bitran J (1996) Clozapine in rapid cycling bipolar disorder. J Clin Psychopharmacol 16:87-90.
64. Frye MA, Denicoff KD, Luckenbaugh D, Kimbrell TA, Dunn RT, Post RM (1997a) Thyroid potentiation in affective illness (abstract). APA New Research Program and Abstracts (abstract NR425):183.
65. Frye MA, Ketter TA, Kimbrell TA, Cora-Locatelli G, Dunn RT, Post RM (1997b) Gabepentin and lamotrigine monotherapy in mood disorder (abstract). Syllabus and Proceedings Summary of the 150th American Psychiatric Association Meeting (abstract 33C):85.
66. Garza-Trevino ES (1990) Verapamil versus lithium in acute mania (abstract). Abstracts of the 143rd Annual Meeting of the American Psychiatric Association (abstract 27):78.
67. Garza-Trevino ES, Overall JE, Hollister LE (1992) Verapamil versus lithium in acute mania. Am J Psychiatry 149:121-122.
68. Gelenberg AJ, Kane JM, Keller MB, Lavori P, Rosenbaum JF, Cole K, Lavelle J (1989) Comparison of standard and low serum levels of lithium for maintenance treatment of bipolar disorder. N Engl J Med 321:1489-1493.
69. George MS, Jones M, Post RM, Putnam F, Mikalauskas K, Leverich GS (1997) The longitudinal course of affective illness: A mathematical model involving chaos theory. Psychiatr Res (in press).
70. Giannini AJ, House WL, Loiselle RH (1984) Antimanic effects of verapamil. Am J Psychiatry 141:1602-1603.
71. Giannini AJ, Taraszewsky R, Loiselle RH (1987) Verapamil and lithium in maintenance therapy of manic patients. J Clin Phannacol 27:980-982.
72. Giannini AJ, Sullivan BS, Folts DJ (1989) Comparison of lithium carbonate, valproic acid and verapamil in the treatment of manic symptoms (abstract). J Clin Pharmacol 29:832.
73. Gitlin MJ, Weiss J (1984) Verapamil as maintenance treatment in bipolar illness: A case report. J Clin Psychopharmacol 4: 341-343.
74. Gitlin MJ, Swendsen J, Heller TL, Hammen C (1995) Relapse and impairment in bipolar disorder. Am J Psychiatry 152:1635-1640.
75. Goodnick PJ (1995) Nimodipine treatment of rapid cyciing bipolar disorder [letter]. J Clin Psychiatry 56:330.
76. Gross G, Xm X, Gastpar M (1991) Trimipramine: Pharmacological reevaluation and comparison with clozapine. Neuropharmacology 30.1159-1166.
77. Grunze H, Walden J, Wolf R, Berger M (1996) Combined treatment with lithium and nimodipine in a bipolar I manic syndrome. Prog Neuropsychopharmcol Biol Psychiatry 20:419-426.
78. Haykal RF, Akiskal HS (1990) Bupropion as a promising approach to rapid cycling bipolar II patients. J Clin Psychiatry 51:450-455.
79. Hendrick V, Altshuler LL, Szuba MP (1994) Is there a role for neuroleptics in bipolar depression? J Clin Psychiatry 55:533-535.
80. Himmelhoch JM, Thase ME, Mallinger AG, Houck P (1991) Tranylcypromine versus imipramine in anergic bipolar depression. AmJ Psychiatry 148:910-916.
81. Hoschl C (1983) Verapamil for depression? [letter]. AmJ Psychiatry 140:1100.
82. Hoschl C, Kozeny J (1989) Verapamil in affective disorders: A controlled, double-blind study. Biol Psychiatry 25:128-140.
83. Hoschl C, Vackova J, Janda B (1992) Mood stabilizing effect of verapamil Bratisl Lek Listy 93:208-209.
84. Hunt N, Silverstone T (1991) Tardive dyskinesia in bipolar affective disorder: A catchment area study. Int Clin Psychopharmacol 6:45-50.
85. Janicak PG, Pandey G, Sharma R, Peterson J, Leach A, Davis JM (1994) Verapamil for acute mania: Preliminary results from a double-blind, placebo-controlled study (abstract). Proceedings of the first International Conference on Bipolar Disorder: 46.
86. Jeste DV, Wyatt RJ (1982) Therapeutic strategies against tardive dyskinesia. Arch Gen Psychiatry 39:803-816.
87. Joffe RT, Singer W (1990) A comparison of triiodothyronine and thyroxine in the potentiation of tricyclic antidepressants. Psychiatry Res 32:241-251.
88. Joffe RT, Gold PW, Uhde TW, Post RM (1984) The effects of carbamazepine on the thyrotropin response to thyrotropin releasing hormone. Psychiatry Res 12:161-166.
89. Kay DS, Naylor GJ, Smith AH, Greenwood C (1984) The therapeutic effect of ascorbic acid and EDTA in manic-depressive psychosis: Double-blind comparisons with standard treatments. Psychol Med 14:533-539.
90. Keck PE, Jr., McElroy SL, Vuckovic A, Friedman LM (1992) Combined valproate and carbamazepine treatment of bipolar disorder. J Neuropsychiatry Clin Neurosci 4.319-322.
91. Keck PE, McElroy SL, Tugrul KC, Bennett JA, Smith JMR (1993) Antiepileptic drugs for the treatment of panic disorder. Neuropsychobiology 27:150-153.
92. Ketter TA, Post RM (1994) Clinical pharmacology and pharmacokinetics of carbamazepine. In Joffe RT, Calabrese JR (eds): Anticonvulsants in Mood Disorders. New York: Marcel Dekker, Inc., pp 147-187.
93. Ketter TA, Pazzaglia PJ, Post RM (1992) Synergy of carbamazepine and valproic acid in affective illness: Case report and review of literature. J Clin Psychopharmacol 12:276-281.
94. Ketter TA, Kimbrell TA, George MS, Stein RM, Willis MW, Benson BE, Frye MA, Cora-Locatelli G, Post RM (1996) Baseline hypermetabolism may predict carbamazepine response, and hypometabolism nimodipine response in mood disorders (abstract). Abstracts of the XXth CINP Congress (abstract 0-5-6): 10.
95. Ketter TA, Frye MA, Cora-Locatelli G, Kimbrell TA, Post RM (1997) Pharmacology and pharmacokinetics of new anticonvulsants. Abstract syllabus and proceeding summary of the 150th American Psychiatric Association (abstract 33a).84-85.
96. Kishimoto A, Okuma T (1986) Antimanic and prophylactic effects of carbamazepine in affective disorders. In Shagass C, Josiassen RC, Bridger WH, Weiss KJ, Stoff D, Simpson GM (eds): Biological Psychiatry 1985. New York: Elsevier, pp 883-885.
97. Kishimoto A (1992) The treatment of affective disorder with carbamazepine: prophylactic synergism of lithium and carbamazepine combination. Prog Neuropsychopharmacol Biol Psych 16:483-493.
98. Kramlinger KG, Post RM (1996) Ultra-rapid and ultradian cycling in bipolar affective illness. Br J Psychiatry 168:314-323.
99. Kramlinger KG, Post RM (1989a) Adding lithium carbonate to carbamazepine: Antimanic efficacy in treatment resistant mania. Acta Psychiatr Scand 79:378-385.
100. Kramlinger KG, Post RM (1989b) The addition of lithium carbonate to carbamazepine: Antidepressant efficacy in treatment-resistant depression. Arch Gen Psychiatry 46:794-800.
101. Kukopulos A, Reginaldi D, Laddomada P, Floris G, Serra G, Tondo L (1980) Course of the manic-depressive cycle and changes caused by treatment. Pharmakopsychiatria Neuropsychopharmakol 13:156-167.
102. Kwamie Y, Persad E, Stancer H (1984) The use of carbamazepine as an adjunctive medication in the treatment of affective disorders: A clinical report. Can J Psychiatry 29:605-608.
103. Lambert PA (1984) Acute and prophylactic therapies of patients with affective disorders using valpromide (dipropylacetamide). In Emrich HM, Okuma T, Muller AA (eds): Anticonvulsants in Affective Disorders. Amsterdam: Excerpta Medica, pp 33-14.
104. Lambert PA, Venaud G (1995) Comparative study of valpromide vs. lithium as prophylactic treatments in affective disorders. Nervure J Psychiatre: 1-9.
105. Lang DG, Wang CM, Cooper BR (1993) Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells. J Pharmacol Exp Ther 266:829-835.
106. Leverich GS, Post RM (1996) Life charting the course of bipolar disorder. Current Review of Mood and Anxiety Disorders. 1:48-61.
107. Lindelius R, Nilsson CG (1992) Flunarizine as maintenance treatment of a patient with bipolar disorder. Am J Psychiatry 149:139.
108. Lusznat RM, Murphy DP, Nunn CM (1988) Carbamazepine vs. lithium in the treatment and prophylaxis of mania. Br J Psychiatry 153:198-204.
109. Manna V (1991) [Bipolar affective disorders and role of intraneuronal calcium. Therapeutic effects of the treatment with lithium salts and/or calcium antagonist in patients with rapid polar inversion]. Minerva Med 82:757-763.
110. Markar HR, Mander AJ (1989) Efficacy of lithium prophylaxis in clinical practice. Br J Psychiatry 15:496-500.
111. McDermut W, Pazzaglia PJ, Huggins T, Mikalauskas K, Leverich GS, Ketter TA, Bartko J, Post RM (1995) Use of single case analyses in off-on-off-on trials in affective illness: A demonstration of the efficacy of nimodipine. Depression 2:259-271.
112. McElroy SL, Keck PE Jr, Pope HG Jr, Hudson JI (1988) Valproate in the treatment of rapid-cycling bipolar disorder. J Clin Psychopharmacol 8:275-279.
113. McElroy SL, Keck PE, Jr, Pope HG, Jr, Hudson JI, Faedda GL, Swann AC (1992) Clinical and research implications of the diagnosis of dysphoric or mixed mania or hypomania. Am J Psychiatry 149:1633-1644.
114. McEvoy JP, Kane JM, Kissling W, Leysen J, Owens D, Sedvall G (1993) Therapeutic use of neuroleptics. Nervenarzt 64 (Suppl 11):1-8.
115. Messenheimer JA (1995) Lamotrigine. Epilepsia 36:S87-S94.
116. Montenegro R, Comide E, Castro JM (1985) Nimodipine in the treatment of involutional depressive syndrome. In Betz E, Deck K, Hoffmeister F (eds): Nimodipine: Pharmacological and Clinical Studies. Stuttgart: Schattauer, pp 345-358.
117. Mosolov SN (1991) [Comparative effectiveness of preventive use of lithium carbonate, carbamazepine and sodium valproate in affective and schizoaffective psychoses]. Zh Nevropatol Psikhiatr 91:78-83.
118. Naylor GJ, Smith AH (1981) Vanadium: A possible aetiological factor in manic depressive illness. Psychol Med 11:249-256.
119. Neumann J, Seidel K, Wunderlich H-P (1984) Comparative studies of the effect of carbamazepine and trimipramine in depression. In Emrich HM, Okuma T, Muller AA (eds): Anticonvulsants in Affective Disorders. Amsterdam: Excerpta Medica, pp 160-166.
120. Nomikos GG, Damsma G, Wenkstern D, Fibiger HC (1989) Acute effects of bupropion on extracellular dopamine concentrations in rat striatum and nucleus accumbens studied by in vivo microdialysis. Neuropsychopharmacology 2:273-279.
121. Nurnberg HG, Finkel JA (1985) Carbamazepine in bipolar-depressed disorder complicated by tricyclic antidepressant switching: A case report. J Clin Psychiatry 46:487-488.
122. O'Connell RA, Mayo JA, Flatow L, Cuthbertson B, O'Brien BE (1991) Outcome of bipolar disorder on long-term treatment with lithium. Br J Psychiatry 159:123-129.
123. Okuma T (1993) Effects of carbamazepine and lithium on affective disorders. Neuropsychobiology 27:138-145.
124. Okuma T, Kishimoto A, Inoue K, Matsumoto H, Ogura A, Matsushita T, Naklao T, Ogura C (1973) Anti-manic and prophylactic effects of carbamazepine on manic-depressive psychosis. Folia Psychiatr Neurol Jpn 27:283-297.
125. Okuma T, Kishimoto A, Inone K (1975) Anti-manic and prophylactic effects of carbamazepine (Tegretol) on manic-depressive psychosis. Seishin Igaku 17:617-630.
126. Okuma T, Inanaga K, Otsuki S, Sarai K, Takahashi R, Hazama H, Mori A, Watanabe M (1981) A preliminary double-blind study of the efficacy of carbamazepine in prophylaxis of manic-depressive illness. Psychopharmacology 73:95-96.
127. Patterson JF (1987) Treatment of acute mania with verapamil [letter]. J Clin Psychopharmacol 7:206-207.
128. Pazzaglia PJ, Post RM, Ketter TA, George MS, Marangell LB (1993) Preliminary controlled trial of nimodipine in ultra-rapid cycling affective dysregulation. Psychiatry Res 49:257-272.
129. Perini GI, Devinsky O, Hauser P, Gallucci WT, Theodore WH, Chrousos GP, Gold PW, Kling MA (1992) Effects of carbamazepine on pituitary-adrenal function in healthy volunteers. J Clin Endocrinol Metab 74:406-412.
130. Placidi GF, Lenzi A, Lazzerini F, Cassano GB, Akiskal HS (1986) The comparative efficacy and safety of carbamazepine versus lithium: A randomized, double-blind 3-year trial in 83 patients. J Clin Psychiatry 47:490-494.
131. Pollack MH, Rosenbaum JF (1987) Verapamil in the treatment of recurrent unipolar depression. Biol Psychiatry 22:779-782.
132. Post RM, Uhde TW, Ballenger JC, Squillace KM (1983) Prophylactic efficacy of carbamazepine in manic-depressive illness. Am J Psychiatry 140:1602-1604.
133. Post RM, Leverich GS, Altshuler L, Mikalauskas K (1992a) Lithium discontinuation-induced refractoriness: Preliminary observations. Am J Psychiatry 149:1727-1729.
134. Post RM, Weiss SRB, Chaung D-M (1992b) Mechanisms of action of anticonvulsants in affective disorders: Comparisons with lithium. J Clin Psychopharmacol 12:23S-35S.
135. Post RM, Leverich GS, Pazzaglia PJ, Mikalauskas K, Denicoff K (1993) Lithium tolerance and discontinuation as pathways to refractoriness. In Birch NJ, Padgham C, Hughes MS (eds): Lithium in Medicine and Biology. Carnforth, UK: Marius Press, pp 71-84.
136. Post RM, Weiss SRB, Chuang D, Ketter TA (1994) Mechanisms of action of carbamazepine in seizure and affective disorders. In Joffe RT, Calabrese JR (eds): Anticonvulsants in Mood Disorders. New York, Marcel Dekker, Inc., pp 43-92.
137. Post RM, Ketter TA, Denicoff K, Pazzaglia PJ, Leverich GS, Marangell LB, Callahan AM, George MS, Frye MA (1996a) The place of anticonvulsant therapy in bipolar illness. Psychopharmacology 128.115-129.
138. Post RM, Pazzaglia PJ, Ketter TA, Denicoff K, Weiss SRB, Hough C, Chuang D-M, Stein R, Frye M (1997b) Carbamazepine and nimodipine in affective illness: Efficacy, mechanisms of action, and interactions. In Montgomery S, Halbreich U (eds): Book IV: Pharmacotherapy of Mood and Cognition. Washington, DC: American Psychiatric Press (in press).
139. Post RM, Kramlinger KG, Joffe RT, Roy-Byrne PP, Rosoff A, Frye MA, Huggins T (1997a) Rapid cycling bipolar affective disorder: lack of relation to hypothyroidism. Psychiatr Res (in press).
140. Post RM, Leverich GS, Rosoff AS, Altshuler LL (1990) Carbamazepine prophylaxis in refractory affective disorders: a focus on long-term follow-up. J Clin Psychopharmacol 10:318-327.
141. Post RM, Uhde TW (1985) are the psychotropic effects of carbamazepine in manic-depressive illness mediated through the limbic system? Psychiatr J Univ Ottawa 10:205-219.
142. Post RM, Weiss SRB, Clark M, Chuang DM, Hough C, Li H (1997c) Lithium, carbamazepine, and valproate in affective illness: Biochemical and neurobiological mechanisms. In Manji H (ed): Mechanisms of Action of the Mood Stabilizers Lithium, Carbamazepine, and Valproate in Affective Illness. Washington, DC: American Psychiatric Press (in press).
143. Prasad AJ (1985) Efficacy of carbamazepine as an antidepressant in chronic resistant depressives. J Indian Med Assoc 83:235-237.
144. Rouillon F, Lejoyeux M, Filteau MJ (1992) Unwanted effects of long-term treatment. In Montgomery SA, Rouillon F (eds): Long-Term Treatment of Depression. Chichester: John Wiley and Sons, pp 81-111.
145. Rubinow DR, Post RM, Gold P, Ballcngcr JC, Wolff EA (1984) The relationship between cortisol and clinical phenomenology of affective illness. In Post RM, Ballenger JC (eds): Neurobiology of Mood Disorders. Baltimore: Williams & Wilkins, pp 271-289.
146. Sachs GS, Lafer B, Stoll AL, Banov M, Thibault AB, Tohen M, Rosenbaum JF (1994) A double-blind trial of bupropion versus desipramine for bipolar depression. J Clin Psychiatry 55: 391-393.
147. Sackeim HA, Prudic J, Devanand DP (1990) Treatment of medication-resistant depression with electroconvulsive therapy. In Tasman A, Goldfinger SM, Kaufmann CA (eds): Review of Psychiatry, Volume 9. Washington, DC: American Psychiatric Press, Inc., pp 91-115.
148. Sarantidis D, Waters B (1981) Predictors of lithium prophylaxis effectiveness. Prog Neuropsychopharmacol 5:507-510.
149. Schaff MR, Fawcett J, Zajecka JM (1993) Divalproex sodium in the treatment of refractory affective disorders. J Clin Psychiatry 54:380-384.
150. Schaffer CB, Mungas D, Rockwell E (1985) Successful treatment of psychotic depression with carbamazepine. J Clin Psychopharmacol 5:233-235.
151. Sernyak MJ, Woods SW (1993) Chronic neuroleptic use in manicdepressive illness. Psychopharmacol Bull 29:375-381.
152. Sethi BB, Tiwari SC (1984) Carbamazepine in affective disorders. In Emrich HM, Okuma T, Muller AA (eds): Anticonvulsants in Affective Disorders. Amsterdam: Excerpta Medics, pp 167-176.
153. Sharma V, Persad E, Mazmanian D, Karunaratne K (1993) Treatment of rapid cycling bipolar disorder with combination therapy of valproate and lithium. Can J Psychiatry 38:137-139.
154. Shopsin B (1983) Bupropion's prophylactic efficacy in bipolar affective illness. J Clin Psychiatry 44.163-169.
155. Silberman EK, Post RM, Nurnberger J, Theodore W, Boulenger J (1985) Transient sensory, cognitive, and affective phenomena in affective illness: A comparison with complex partial epilepsy. Br J Psychiatry 146:81-89.
156. Silverstone T (1984) Response to bromocriptine distinguishes bipolar from unipolar depression [letter]. Lancet 1:903-904.
157. Small JG (1990) Anticonvulsants in affective disorders. Psychopharmacol Bull 26:25-36.
158. Solomon I, Williamson P (1986) Verapamil in bipolar illness. Can J Psychiatry 31:442-444.
159. Stoll AL, Sachs GS, Cohen BM, Lafer B, Christensen JD, Renshaw PF (1996) Choline in the treatment of rapid-cycling bipolar disorder: clinical and neurochemical findings in lithium-treated patients. Biol Psychiatry 40:382-388.
160. Stuppaeck C, Barnas C, Miller C, Schwitzer J, Fleischhacker WW (1990) Carbamazepine in the prophylaxis of mood disorders. J Clin Psychopharmacol 10:39-42.
161. Suppes T, McElroy SL, Gilbert J, Dessain EC, Cole JO (1992) Clozapine in the treatment of dysphoric mania. Biol Psychiatry 32:270-280.
162. Svestka J, Nahunek K, Ceskova E, Korbicka J (1985) Carbamazepine prophylaxis of affective psychoses (intraindividual comparison with lithium carbonate). Activ Nerv Sup 27:261-262.
163. Svestka J, Dcskova E, Rysanek R, Nahunek K (1991) Antiepileptics in the treatment of endogenous depressions. Presented at the 5th World Congress of Biological Psychiatry, Florence, Italy, June 9-14.
164. Swann AC, Secunda SK, Koslow SH, Katz MM, Bowden CL, Maas JW, Davis JM, Robins E (1991) Mania: Sympathoadrenal function and clinical state. Psychiatry Res 37:195-205.
165. Swann AC, Bowden CL, Morris D, Calabrese JR, Petty F, Small J, Dilsaver SC, Davis JM (1997) Depression during mania: Treatment response to lithium or divalproex. Arch Gen Psychiatry 54:37-42.
166. Tamminga CA, Lahti AC (1996) The new generation of antipsychotic drugs. Int Clin Psychopharmacol 11:73-76.
167. Vadnal R, Parthasarathy R (1995) Myo-inositol monophosphatase: Diverse effects of lithium, carbamazepine, and valproate. Neuropsychopharmacology 12:277-285.
168. Varney NR, Garvey MJ, Cook BL, Campbell DA, Roberts RJ (1993) Identification of treatment-resistant depressives who respond favorably to carbamazepine. Ann Clin Psychiatry 5:117-122.
169. Vestergaard P (1992) Treatment and prevention of mania: A Scandinavian perspective. Neuropsychopharmacology 7:249-260.
170. Waddington JL, Youssef HA (1988) Tardive dyskinesia in bipolar affective disorder: Aging, cognitive dysfunction, course of illness, and exposure to neuroleptics and lithium. Am J Psychiatry 145:613-616.
171. Walden J, Grunze H, Hellhammer D, Fritze J, Berger M (1994) Treatment of depressive episodes with the calcium antagonist nimodipine: Single case reports (abstract). Neuropsychopharmacology 10:2335.
172. Walton SA, Berk M, Brook S (1996) Superiority of lithium over verapamil in mania: A randomized, controlled, single-blind trial. In: J Clin Psychiatry 57:543-546.
173. Watkins SE, Callender K, Thomas DR, Tidmarsh SF, Shaw DM (1987) The effect of carbamazepine and lithium on remission from affective illness. Br J Psychiatry 150:180-182.
174. Wehr TA, Goodwin FK (1979) Rapid cycling in manic-depressives induced by tricyclic antidepressants. Arch Gen Psychiatry 36:555-559.
175. Weiss SRB, Clark M, Rosen JB, Smith MA, Post RM (1995) Contingent tolerance to the anticonvulsant effects of carbamazepine: Relationship to loss of endogenous adaptive mechanisms. Brain Res Rev 20:305-325.
176. Wright G, Galloway L, Kim J, Dalton M, Miller L, Stern W (1985) Bupropion in the long-term treatment of cyclic mood disorders: Mood stabilizing effects. J Clin Psychiatry 46:22-25.
177. Wunderlich H-P, Grunes JU, Neumann J, Zahlten W (1983) Antidepressive therapy with carbamazepine (Finlepsin). Schweiz Arch Neurol Neurochir Psychiatr 133:363-371.
178. Yamada N, Martin-Iverson T, Daimon K, Tsujimoto T, Takahashi S (1995) Clinical and chronobiological effects of light therapy on nonseasonal affective disorders. Biol Psychiatry 37:866-873.
179. Young LT, Robb J, Patelis-Siotis I, MacDonald C, Joffe RT (1997) Gabepentin in bipolar depression: a case series (abstract). APA New Research Program and Abstracts (abstract NR452):190.
180. Zis AP, Cowdry RW, Wehr TA, Muscettola G, Goodwin FK (1979) Tricyclic-induced mania and MHPG excretion. Psychiatry Res 1:93-99.