Expression of tumour associated antigens in normal, benign and malignant human mammary epithelial tissue: A comparative immunohistochemical study

Anticancer Research

Volumn 17, Issue 6 D, 1997, Pages 4287-4292

  Croce, Maria Virginia ^a   Colussi, Andrea G ^a   Price, Mike R ^b   Segal Eiras, Amada ^a  

^a UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Breast cancer; CEA; Le(y) hapten; Monoclonal antibodies; MUC mucin

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; HAPTEN; MONOCLONAL ANTIBODY; MUCIN; TUMOR ANTIGEN;

ANTIGEN EXPRESSION; ANTIGENICITY; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CELL MEMBRANE; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GLYCOSYLATION; HUMAN; HUMAN CELL; IMMUNOCHEMISTRY; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL;

EID: 0031427011     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Yan PS, Ho SB, Itzkowitz SH, Byrd JC, Siddiqui B and Kim Y: Expression of native and deglycosylated colon cancer mucin antigens in normal and malignant epithelial tissues. Lab Invest 62: 698-706, 1990.
2. Ohshio G, Imamura T, Imamura M, Yamabe H, Sakahara H, Nakada H and Yamashina Y: Distribution of Tn antigen recognized by an anti-Tn monoclonal antibody (MLS128) in normal and malignant tissues of the digestive tract. J Cancer Res Clin Oncol 121: 247-252. 1995
3. Tashiro Y, Yonezawa S, Kim YS and Sato E: Immunohistochemical study of mucin carbohydrates and core proteins in human ovarian tumors. Human Pathol 25: 364-372, 1994.
4. McGuckin MA, Walsh MD, H4hn BG, Ward BG, Wright G: Prognostic significance of MUC1 epithelial mucin expression in breast cancer. Human Pathol 26: 432-439, 1995.
5. Osako M, Yonezawa S, Siddiki B, Huang J, Ho JJL, Kim Y and Sato E: Immunohistochemical study of mucin carbohydrates and core proteins in human pancreatic tumors. Cancer 71: 2191-2199, 1993.
6. Chaux, P: Dentritic cells and immune function in cancer. Pathol Biol Paris 43: 897-903, 1995.
7. Price MR, Pugh J, Hudecz F, Griffiths W, Jacobs E, Symonds IM, Clarke AJ, Chan WC and Baldwin RW: C595-a monoclonal antibody against the protein core of human urinary epithelial mucin commonly expressed in breast carcinomas. Brit J Cancer 61: 681-686, 1990.
8. Briggs S, Price MR and Tendler S: Fine specificity of antibody recognition of carcinoma-associated epithelial mucins: antibody binding to synthetic peptide epitopes. Eur J Cancer 29A: 230-237, 1993.
9. Taylor-Papadimitriou J, Stewart L, Burchell J and Beverly P: The polymorphic epithelial mucin as a target for immunotherapy. Ann New York Acad Sci 690: 69-79, 1993.
10. Price MR: Epitopes of carcinoembryonic antigen (CEA) defined by monoclonal antibodies. Brit J Cancer 57: 165-169, 1988.
11. Brown A, Feizi T, Gooi HC, Embleton MJ and Baldwin RW:. A monoclonal, antibody against human colonie adenoma recognises a difucosylated type-2 blood group chains. Biosci Rep 3: 163-169, 1983.
12. Portiansky EL and Gimeno EJ: A new epitope retrieval method for the detection of structural cytokeratins in the bovine prostatic tissue. Applied Immunohistochem 4: 208-214, 1996.
13. Sukumar S and McKenzie K: Breast cancer prevention strategies for the twenty-first century. Molecular Medicine Today 2: 453-459, 1996.
14. Dupont WD, Pari FF, Hartmann WH, Brinton LA, Worrell JA, Schuyler PA, Plummer WD: Breast cancer risk associated with proliferative breast disease and atypical hyperplasia. Cancer 71: 1258-1265, 1993.
15. Sloane JP: Evidence for premalignant lesions in the human breast. Eur J Cancer Prev 2: 17-21, 1993.
16. Schmitt FC, Figueiredo P and Lacerda M: Simple mucin-type carbohydrate antigens (T, sialosyl-T and sialosyl-Tn) in breast carcinogenesis. Virchows Arch 427: 251-258, 1995
17. Weinberg DS: Quantitative immunocytochemistry in pathology in Image Analysis. A primer for pathologists (AM Marchevsky and PH Bartels, eds) Chapter 8: 235-260, 1994.
18. Sell S: Cancer-associated carbohydrates identified by monoclonal antibodies. Human Pathol 21: 1003-1019, 1990.
19. Price MR and Tendler SJB: Polymorphic epithelial mucins (PEM): molecular analysis and association with breast cancer. Breast 2: 3-7, 1993.
20. Burchell J, Gendler SJ, Taylor Papadimitriou J, Girling A, Lewis A, Millis R and Lamport D: Development and characterization of breast cancer reactive monoclonal antibodies directed to the protein core of the human milk mucin. Cancer Res 47: 5476-5482, 1987.
21. Kotera Y, Fontenot JD, Pecher G, Mekgar RS and Finn O: Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic and colon cancer patients. Cancer Res 54: 2856-2860, 1994.
22. Croce MV, Price MR and Segal-Eiras A: Expression of monoclonal antibody defined antigens in fractions isolated from human breast carcinomas and patients' serum. Cancer Immunol Immunother 40: 132-137, 1995.
23. Finn O, Jerome KR, Henderson RA, Pecher G, Domenech N, MagarianBlander J and Barratt-Boyes SM: MUC-1 epithelial mucin-based immunity and cancer vaccines. Immunol Rev 145: 61-89, 1995.
24. Price, MR, Edwards, S and Baldwin RW: Association of the Y hapten with glycoproteins, glycolipids and carcinoembryonic antigen in colorectal carcinoma. Cancer Lett 33: 83-89, 1986.
25. Croce MV, Price MR, Segal-Eiras A: Antigen heterogeneity in advanced colorectal and breast cancer. Int J Oncol 9: 459-463, 1996.
26. Kannagi R, Fukushi Y, Tachikawa T, Noda A, Shin S, Shigeta K, Hiraiwa N, Fukuda Y, Inamoto T, Hakomori S and Imura H: Quantitative and qualitative characterization of human cancer-associated serum glycoprotein antigens expressing fucosyl or sialyl-fucosyl type 2 chain polylactosamine. Cancer Res 46: 2619-2626, 1986.
27. Fleuren-GJ, Gorter-A, Kuppen-PJ, Litvinov-S, Wamaar-SO: Tumor heterogeneity and immunotherapy of cancer. Immunol Rev 145: 91-122, 1995.