Antigen heterogeneity in advanced colorectal and breast cancer

International Journal of Oncology

Volumn 9, Issue 3, 1996, Pages 459-463

  Croce, María Virginia ^a   Price, Mike R ^b   Segal Eiras, Amada ^a,c  

^a UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

Author keywords

antigen heterogeneity; breast cancer; colorectal cancer

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; EPITOPE; GLYCOLIPID; HAPTEN; MONOCLONAL ANTIBODY; MUCIN; TUMOR ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; BREAST CANCER; COLORECTAL CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; TUMOR DIAGNOSIS;

EID: 0029788197     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.9.3.459     Document Type: Article

References (28)

1. Price MR and Tendler SJB: Polymorphic epithelial mucins (PEM): molecular characteristics and association with breast cancer. Breast 2: 3-7, 1993.
2. a carrying glycoproteins produced by colon carcinoma cells using a novel monoclonal antibody. Cancer Res 53: 755-761, 1993.
3. x-related antigen expression in human malignant and non-malignant colonie tissues. Cancer Res 46: 2627-2632, 1986.
4. Hakomori S: Aberrant glycosylation in cancer cell membranes as focused on glycolipids: overview and perspectives. Cancer Res 45: 2405-2414, 1985.
5. Sculier JP, Body JI, Jacobowitz D and Fruhling J: Value of CEA determination in histological fluids and tissues. Eur J Cancer Clin Oncol: 23: 1091-1093, 1987.
6. x expression. Cancer Res 53: 4082-4088, 1993.
7. Hertzog P, Robinson H, Ma J, et al: Oncofetal expression of the human intestinal mucin glycoprotein antigens in gastrointestinal epithelium defined by monoclonal antibodies. Int J Cancer 48: 355-363, 1991.
8. Kim YS, Gum JR, Byrd JC and Toribana N: The structure of human intestinal mucins. Am Rev Respir Dis 144: 10-14, 1991.
9. Singhal A and Hakomori S-I: Molecular changes in carbohydrate antigens associated with cancer. Bioessays 12: 223-230, 1990.
10. Ho SB and Kim YS: Carbohydrate antigens on cancer-associated mucin-like molecules. Semin Cancer Biol 2: 389-400, 1992.
11. Zotter S, Hagemann PC, Lossnitzer A, et al: Tissue and tumour districbution of human polymorphic epithelial mucin. Cancer Rev 11-12: 55-79, 1988.
12. Price MR, Hudecz F, O'Sullivan C, et al: Immunological and structural features of the protein core of human polymorphic epithelial mucin. Mol Immunol 27: 795-802, 1990.
13. Price MR, Sekowski M, Yang GY, et al: Reactivity of an antihuman gastric carcinoma monoclonal antibody with gastrointestinal mucin core-related peptides. Cancer Immunol Immunother 33: 80-84, 1991.
14. Price MR: Epitopes of carcinoembryonic antigen (CEA) defined by monoclonal antibodies. Br J Cancer 57: 165-169, 1988.
15. Brown A, Feizi T, Gooi HC, et al: A monoclonal antibody against human colonic adenoma recognises a difucosylated type-2 blood group chains. Biosci Rep 3: 163-169, 1983.
16. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-681, 1970.
17. Towbin H, Staehelin T and Gordon J: Electrophoretic transfer of protein for polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76: 4350-4354, 1979.
18. Bover L, Barrio M, Slavutsky I, et al: Description of a new human breast cancer cell line, IIB-BR-G, established from a primary undifferentiated tumour. Breast Cancer Res Treat XX: 47-56, 1991.
19. Itzkowitz S, Bloom E, Kokal W, et al: Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients. Cancer 66: 1960-1966, 1990.
20. Schwartz B, Bresalier R and Kim Y: The role of mucin in colon-cancer metastasis. Int J Cancer 52: 60-65, 1992.
21. Croce MV, Price MR and Segal-Eiras A: Expression of monoclonal antibody-defined antigens in fractions isolated from human breast carcinomas and patients' serum. Cancer Immunol Immunother 40: 132-137, 1995.
22. Kotera Y, Fontenot D, Pecher G, et al: Humoral immunity against a tandem repeat epitope of human mucin MUC1 in sera from breast, pancreatic and colon cancer patients. Cancer Res 54: 2856-2860, 1994.
23. Hinoda Y, Nakagawa N, Nakamua H, et al: Detection of a circulating antibody against a peptide epitope on a mucin core protein, MUC1, in ulcerative colitis. Immunol Lett 35: 163-168, 1993.
24. Jessup JM, Giavazzi R, Campbell D, et al: Metastatic potential of human colorectal carcinomas implanted into nude mice; prediction of clinical outcome in patients operated upon for cure. Cancer Res 49: 6906-6910, 1989.
25. Hauck W and Stanners C: Control of carcinoembryonic antigen gene family expression in a differentiating colon carcinoma cell line, Caco-2. Cancer Res 51: 3526-3533, 1991.
26. Price MR, Edwards S and Baldwin RW: Association of the Y hapten with glycoproteins, glycolipids and carcinoembryonic antigen in colorectal carcinoma. Cancer Lett 33: 83-89, 1986.
27. y) blood group antigen expression in epithelial ovarian cancer. Int J Cancer 65: 406-412, 1996.
28. Hamada Y, Yamamura M, Hioki K, et al: Immunohistochemical study of carcinoembryonic antigen in patients with colorectal cancer. Cancer 55: 136-141, 1985.