Vascular endothelial growth factor (VEGF) in normal human corneal epithelium: Detection and physiological importance

Acta Ophthalmologica Scandinavica

Volumn 75, Issue 6, 1997, Pages 649-652

  Van Setten, Gysbert B ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Corneal neovascularization; Corneal wound healing; Growth factors; Heparin binding growth factors; Hypoxia

Indexed keywords

ANTIBODY; VASCULOTROPIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CASE REPORT; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA NEOVASCULARIZATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL;

EID: 0031426703     PISSN: 13953907     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0420.1997.tb00623.x     Document Type: Article

References (25)

1. Adamis AP, Shima DT, Yeo K-T, Yea TK, Brown LF, Berse B, D'Amore PA & Folkman J (1993): Synthesis and secretion of vacular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem Biophys Res Commun 193: 631-638.
2. Arentsen JJ (1986): Corneal neovascularization in contact lens wearers. Int Ophthalmol Clin 26: 15-23.
3. Bednarz J, Weich HA, Rodokanaki-von Schrenck A & Engelmann K (1995): Expression of genes coding growth factors and growth factor receptors in differentiated and dedifferentiated human corneal endothelial cells. Cornea 14: 372-381.
4. Chan-Ling T & Keshet E (1995): Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF): expression by neuroglia. J Neurosci 15: 4738-4747.
5. Clauss M, Gerlach M, Gerlach H, Brett J, Wang F, Familetti PC, Pan YC, Olander JV, Conolly DT & Stern D (1990): Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 172: 1535-1539.
6. Detmar M, Yeo KT, Nagy JA, Van de Water L, Brown LF, Berse B, Elicker BM, Ledbetter S & Dvorak HF (1995): Keratinocyte-derived vascular permeability factor vascular endothelial growth factor): is a potent mitogen for dermal microvascular endothelial cells. J Invest Dermatol 105: 44-50.
7. Dvorak HF, Detmar M, Claffey KP, Nagy JA, van de Water L & Senger DR (1995): Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation. Int Arch Allergy Immunol 107: 233-235.
8. Ferrara N, Houck KA, Jakeman LB, Winer J & Leung DW (1991): The vascular endothelial growth factor family of polypeptides. J Cell Biochem 47: 211-218.
9. Gruber BL, Marchese MJ & Kew R (1995): Angiogenic factors stimulate mast-cell migration. Blood 86: 2488-2493.
10. Guerrin M, Moukadiri H, Chollet P, Moro F, Dutt K, Malecaze F & Plouët J (1995): Vasculotropin/vascular endothelial growth factor is an autocrine growth factor for human retinal pigment epithelial cells cultured in vitro. J Cell Physiol 164: 385-394.
11. Hata Y, Nakagawa K, Ishibashi T, Inomata H, Ueno H & Sueishi K (1995): Hypoxia-induced expression of vascular endothelial growth factor by retinal glial cells promotes in vitro angiogenesis. Virchows Arch 426: 479-486.
12. Ikeda E, Achen MG, Breier G & Risau W (1995): Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma Cells. J Biol Chem 270: 19761-19766.
13. Liu Y, Cox SR, Morita T & Kourembanas S (1995): Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer. Circ Res 77: 638-643.
14. Ohashi Y, Motokura M, Kinoshita Y, Mano T, Watanabe H, Kinoshita S, Manahe R, Oshiden K & Yanaihara C (1989): Presence of epidermal growth factor in human tears. Invest Ophthalmol Vis Sci 30: 1879-1882.
15. Plate KH, Breier G, Welch HA & Riesau W (1992): Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature 359: 845-848.
16. Roberts WG & Palade GE (1995): Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor. J Cell Sci 108: 2369-2379.
17. Schultz GS, Khaw PT, Oxford K, Macauley S, van Setten GB & Chegini N (1994): Growth factors in corneal wound healing. Eye 8: 184-187.
18. Senger DR, Brown LF, Claffey KP & Dvorak HF (1994): Vascular permeability factor, tumor angiogenesis and stroma generation. Invasion Metastasis 14: 385-394.
19. Shima DT, Deutsch U & D'Amore PA (1995): Hypoxic induction of vascular endothelial growth factor (VEGF): in human epithelial cells is mediated by increases in mRNA stability. FEBS Lett 370: 203-208.
20. van Setten GB (1990): Epidermal growth factor in human tear fluid: Increased release but decreased concentrations during reflex tearing. Curr Eye Res 9: 79-83.
21. van Setten GB, Tervo T, Tarkkanen A, Pesonen K, Viinikka L & Perheentupa J (1989): Epidermal growth factor is a constant component of human tear fluid. Graefe's Arch Clin Exp Ophthalmol 227: 84-87.
22. van Setten GB, Tervo K, Virtanen I, Tarkkanen A & Tervo T (1990): Immunohistochemical demonstration of epidermal growth factor in the lacrimal and submandibular glands of rats. Acta Ophthalmol (Copenh) 68: 477-480.
23. van Setten GB, McCauley S, Humphreys-Beher M & Schultz GS (1996): Detection of transforming growth factor-α in human tear fluid, and protein in rat lacrimal glands and characterization of transforming growth factor-α in human tears. Invest Ophthalmol Vis Sci 37: 166-173.
24. van Setten G-B & Schultz GS (1994): Transforming growth factor alpha is a constant component of human tear fluid. Graefe's Arch Clin Exp Ophthalmol 232: 523-526.
25. Watanabe H, Ohashi Y, Kinoshita S, Danjo S, Manabe R, Yanaihara C & Oshiden K (1989): Localization of epidermal growth factor in ocular and periocular tissues of rats. Invest Ophthalmol Vis Sci (Suppl) 30: 149.