-
1
-
-
0030071749
-
An immunoglobulin mutator that targets G-C base pairs
-
Bach, J. and Wabl, M. (1996) An immunoglobulin mutator that targets G-C base pairs. Proc. Natl. Acad. Sci. U.S.A. 93, 851-855.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 851-855
-
-
Bach, J.1
Wabl, M.2
-
2
-
-
0027227311
-
Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes
-
Betz, A. G., Neuberger, M. S. and Milstein, C. (1993) Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunology Today 14, 405-411.
-
(1993)
Immunology Today
, vol.14
, pp. 405-411
-
-
Betz, A.G.1
Neuberger, M.S.2
Milstein, C.3
-
3
-
-
0024159308
-
Genetics of the phosphocholine-specific antibody response to Streptococcus pneumoniae
-
Claflin, J. L. and Berry, J. (1988) Genetics of the phosphocholine-specific antibody response to Streptococcus pneumoniae. J. Immunol. 141, 4012-4019.
-
(1988)
J. Immunol.
, vol.141
, pp. 4012-4019
-
-
Claflin, J.L.1
Berry, J.2
-
4
-
-
0024826077
-
Increased vesicular transport and decreased mitochondrial content in blood-brain barrier endothelial cells during experimental autoimmune encephalomyelitis
-
Claudio, L., Kress, Y., Norton, W. T. and Brosnan, C. F. (1989) Increased vesicular transport and decreased mitochondrial content in blood-brain barrier endothelial cells during experimental autoimmune encephalomyelitis. Am. J. Pathol. 135, 1157-1168.
-
(1989)
Am. J. Pathol.
, vol.135
, pp. 1157-1168
-
-
Claudio, L.1
Kress, Y.2
Norton, W.T.3
Brosnan, C.F.4
-
5
-
-
0028915454
-
Regulation of lymphocyte survival by the BCL-2 gene family
-
Cory, S. (1995) Regulation of lymphocyte survival by the BCL-2 gene family. Annu. Rev. Immunol. 13, 513-543.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 513-543
-
-
Cory, S.1
-
6
-
-
0019391404
-
A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody
-
Crews, S., Griffin, J., Huang, H., Calame, K. and Hood, L. (1981) A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody. Cell 25, 59-61.
-
(1981)
Cell
, vol.25
, pp. 59-61
-
-
Crews, S.1
Griffin, J.2
Huang, H.3
Calame, K.4
Hood, L.5
-
7
-
-
0031569118
-
Analysis of the frequency and pattern of somatic mutations within non-productively rearranged human variable heavy chain genes
-
Dorner, T., Brezinschek, H., Brezinschek, R. I., Foster, S. J., Domiati-Saad, R. and Lipsky, P. E. (1997) Analysis of the frequency and pattern of somatic mutations within non-productively rearranged human variable heavy chain genes. J. Immunol. 158, 2779-2789.
-
(1997)
J. Immunol.
, vol.158
, pp. 2779-2789
-
-
Dorner, T.1
Brezinschek, H.2
Brezinschek, R.I.3
Foster, S.J.4
Domiati-Saad, R.5
Lipsky, P.E.6
-
8
-
-
0028466384
-
Analysis of the B cell progenitor compartment at the level of single cells
-
Ehlich, A., Martin, V., Muuler, W. and Rajewsky, K. (1994) Analysis of the B cell progenitor compartment at the level of single cells. Curr. Biol. 4, 573-583.
-
(1994)
Curr. Biol.
, vol.4
, pp. 573-583
-
-
Ehlich, A.1
Martin, V.2
Muuler, W.3
Rajewsky, K.4
-
9
-
-
0029924630
-
Frequent aberrant immunoglobulin gene rearrangements in pro-B cells revealed by a bcl-xL transgene
-
Fang, W., Mueller, D. L., Pennell, C. A., Rivard, J. J., Li, Y.-S., Hardy, R. R., Schlissel, M. S. and Behrens, T. W. (1996) Frequent aberrant immunoglobulin gene rearrangements in pro-B cells revealed by a bcl-xL transgene. Immunity 4, 291-299.
-
(1996)
Immunity
, vol.4
, pp. 291-299
-
-
Fang, W.1
Mueller, D.L.2
Pennell, C.A.3
Rivard, J.J.4
Li, Y.-S.5
Hardy, R.R.6
Schlissel, M.S.7
Behrens, T.W.8
-
10
-
-
0028217720
-
Chimeric molecules created by gene amplification interfere with the analysis of somatic hypermutation of murine immunoglobulin genes
-
Ford, J. E., McHeyzer-Williams, M. G. and Lieber, M. (1994) Chimeric molecules created by gene amplification interfere with the analysis of somatic hypermutation of murine immunoglobulin genes. Gene 142, 279-283.
-
(1994)
Gene
, vol.142
, pp. 279-283
-
-
Ford, J.E.1
McHeyzer-Williams, M.G.2
Lieber, M.3
-
11
-
-
15844413140
-
Negative selection of human germinal center B cells by prolonged BCR cross-linking
-
Galibert, L., Burdin, N., Barhelemy, C., Meffre, G., Durand, I., Garcia, E., Garrone, P., Rousset, F., Banchereau, J. and Liu, Y. J. (1996) Negative selection of human germinal center B cells by prolonged BCR cross-linking. J. Exp. Med. 183, 2075-2085.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2075-2085
-
-
Galibert, L.1
Burdin, N.2
Barhelemy, C.3
Meffre, G.4
Durand, I.5
Garcia, E.6
Garrone, P.7
Rousset, F.8
Banchereau, J.9
Liu, Y.J.10
-
12
-
-
0030450401
-
Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation
-
Goyenechea, B. and Milstein, C. (1996) Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation. Proc. Natl. Acad. Sci. U.S.A. 93, 13979-13984.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 13979-13984
-
-
Goyenechea, B.1
Milstein, C.2
-
13
-
-
0028785538
-
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance
-
Han, S., Zheng, G., Dal Porto, J. and Kelsoe, G. (1995) In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance. J. Exp. Med. 182, 1635-1644.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1635-1644
-
-
Han, S.1
Zheng, G.2
Dal Porto, J.3
Kelsoe, G.4
-
14
-
-
0027447188
-
Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
-
Hartley, S. B., Cooke, M. P., Fulcher, D. A., Harris, A., Cory, S., Basten, A. and Goodnow, C. C. (1993) Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death. Cell 72, 325-335.
-
(1993)
Cell
, vol.72
, pp. 325-335
-
-
Hartley, S.B.1
Cooke, M.P.2
Fulcher, D.A.3
Harris, A.4
Cory, S.5
Basten, A.6
Goodnow, C.C.7
-
15
-
-
0025835716
-
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death
-
Hockenbery, D. M., Zutter, M., Hickey, W., Nahm, M. H. and Korsmeyer, S. J. (1991) BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl. Acad. Sci. U.S.A. 88, 6961-6965.
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 6961-6965
-
-
Hockenbery, D.M.1
Zutter, M.2
Hickey, W.3
Nahm, M.H.4
Korsmeyer, S.J.5
-
16
-
-
0028036895
-
Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of bcl-2
-
Krajewsky, S., Krajewski, M., Shabik, A., Miyashita, T., Wang, H. G. and Reed, J. C. (1994) Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of bcl-2. Am. J. Pathol. 145, 1323-1336.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1323-1336
-
-
Krajewsky, S.1
Krajewski, M.2
Shabik, A.3
Miyashita, T.4
Wang, H.G.5
Reed, J.C.6
-
17
-
-
0024338553
-
Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response
-
Levy, N. S., Malipiero, U. V., Lebecque, S. G. and Gearhart, P. J. (1989) Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response. J. Exp. Med. 169, 2007-2019.
-
(1989)
J. Exp. Med.
, vol.169
, pp. 2007-2019
-
-
Levy, N.S.1
Malipiero, U.V.2
Lebecque, S.G.3
Gearhart, P.J.4
-
18
-
-
0025873842
-
Germinal center cells express bcl-2 protein after activation by signals which prevent their entry into apoptosis
-
Liu, Y., Mason, D. Y., Johnson, G. D., Abbot, S. and MacLennan, I. C. M. (1991) Germinal center cells express bcl-2 protein after activation by signals which prevent their entry into apoptosis. Eur. J. Immunol. 21, 1905-1910.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 1905-1910
-
-
Liu, Y.1
Mason, D.Y.2
Johnson, G.D.3
Abbot, S.4
MacLennan, I.C.M.5
-
19
-
-
0024799016
-
Mechanism of antigen-driven selection in germinal centres
-
Liu, Y.-J., Joshua, D. E., Williams, G. T., Smith, C. A., Gordon, J. and MacLennan, I. C. M. (1989) Mechanism of antigen-driven selection in germinal centres. Nature 342, 929-931.
-
(1989)
Nature
, vol.342
, pp. 929-931
-
-
Liu, Y.-J.1
Joshua, D.E.2
Williams, G.T.3
Smith, C.A.4
Gordon, J.5
MacLennan, I.C.M.6
-
20
-
-
0023161407
-
Somatic mutation in anti-phosphorylcholine antibodies
-
Malipiero, U. V., Levy, N. S. and Gearhart, P. J. (1987) Somatic mutation in anti-phosphorylcholine antibodies. Immun. Rev. 96, 59-74.
-
(1987)
Immun. Rev.
, vol.96
, pp. 59-74
-
-
Malipiero, U.V.1
Levy, N.S.2
Gearhart, P.J.3
-
21
-
-
0030732228
-
Specific antibodies reveal an alternate pattern of somatic mutation
-
in press
-
Manheimer-Lory, A. and Diamond, B. (1997) Specific antibodies reveal an alternate pattern of somatic mutation. J. Clin. Invest, in press.
-
(1997)
J. Clin. Invest
-
-
Manheimer-Lory, A.1
Diamond, B.2
-
22
-
-
0029917123
-
Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax, but not the survival gene bcl-2
-
Martinez-Valdez, H., Guret, C., de Bouteiller, O., Fugier, I., Banchereau, J. and Liu, Y. J. (1991) Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax, but not the survival gene bcl-2. J. Exp. Med. 183, 971-977.
-
(1991)
J. Exp. Med.
, vol.183
, pp. 971-977
-
-
Martinez-Valdez, H.1
Guret, C.2
De Bouteiller, O.3
Fugier, I.4
Banchereau, J.5
Liu, Y.J.6
-
23
-
-
0029938724
-
Regulation of cell division cycle progression by bcl-2 expression: A potential mechanism for inhibition of programmed cell death
-
Mazel, S., Burtrum, D. and Petrie, H. T. (1996) Regulation of cell division cycle progression by bcl-2 expression: A potential mechanism for inhibition of programmed cell death. J. Exp. Med. 183, 2219-2226.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2219-2226
-
-
Mazel, S.1
Burtrum, D.2
Petrie, H.T.3
-
25
-
-
0027527099
-
Disappearance of the lymphoid system in bcl-2 homozygous mutant chimeric mice
-
Nakayama, K., Negishi, I., Kuida, K., Shinkai, Y., Louie, M. C., Fields, L. E., Lucas, P. J., Stewart, V., Alt, F. W. and Loh, D. Y. (1993) Disappearance of the lymphoid system in bcl-2 homozygous mutant chimeric mice. Science 261, 1584-1588.
-
(1993)
Science
, vol.261
, pp. 1584-1588
-
-
Nakayama, K.1
Negishi, I.2
Kuida, K.3
Shinkai, Y.4
Louie, M.C.5
Fields, L.E.6
Lucas, P.J.7
Stewart, V.8
Alt, F.W.9
Loh, D.Y.10
-
26
-
-
0027260581
-
The bcl-2 gene product inhibits clonal deletion of self-reactive B lymphocytes in the periphery but not in the bone marrow
-
Nisitani, S., Tsubata, T., Murakami, M., Okamoto, M. and Honjo, T. (1993) The bcl-2 gene product inhibits clonal deletion of self-reactive B lymphocytes in the periphery but not in the bone marrow. J. Exp. Med. 178, 1247-1254.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1247-1254
-
-
Nisitani, S.1
Tsubata, T.2
Murakami, M.3
Okamoto, M.4
Honjo, T.5
-
27
-
-
0025255538
-
Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
-
Nunez, G., London, L., Hockenbery, D., Alexander, M., McKearn, J. P. and Korsmeyer, S. J. (1990) Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol. 144, 3602-3610.
-
(1990)
J. Immunol.
, vol.144
, pp. 3602-3610
-
-
Nunez, G.1
London, L.2
Hockenbery, D.3
Alexander, M.4
McKearn, J.P.5
Korsmeyer, S.J.6
-
28
-
-
0030476922
-
The cell death inhibitor bcl-2 and its homologues influence control of cell cycle entry
-
O'Reilly, L., Huang, D. C. S. and Strasser, A. (1996) The cell death inhibitor bcl-2 and its homologues influence control of cell cycle entry. EMBO J. 15, 6979-6990.
-
(1996)
EMBO J.
, vol.15
, pp. 6979-6990
-
-
O'Reilly, L.1
Huang, D.C.S.2
Strasser, A.3
-
29
-
-
0028892789
-
Immunoblot analysis of cellular expression of bcl-2 family proteins, bcl-2, bax, bcl-2 and mcl-1 in human peripheral blood and lymphoid tissues
-
Ohta, K., Iwai, K., Kasahara, Y., Taniguchi, N., Krajewski, S., Reed, J. C. and Miyawaki, T. (1995) Immunoblot analysis of cellular expression of bcl-2 family proteins, bcl-2, bax, bcl-2 and mcl-1 in human peripheral blood and lymphoid tissues. Int. Immunol. 7, 1817-1825.
-
(1995)
Int. Immunol.
, vol.7
, pp. 1817-1825
-
-
Ohta, K.1
Iwai, K.2
Kasahara, Y.3
Taniguchi, N.4
Krajewski, S.5
Reed, J.C.6
Miyawaki, T.7
-
30
-
-
0029059370
-
Soluble antigen can cause enhanced apoptosis of germinal-centre B cells
-
Pulendran, B., Kannourakis, G., Nouri, S., Smith, K. G. and Nossal, G. J. (1995) Soluble antigen can cause enhanced apoptosis of germinal-centre B cells. Nature 375, 331-334.
-
(1995)
Nature
, vol.375
, pp. 331-334
-
-
Pulendran, B.1
Kannourakis, G.2
Nouri, S.3
Smith, K.G.4
Nossal, G.J.5
-
31
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky, K. (1996) Clonal selection and learning in the antibody system. Nature 381, 751-758.
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
32
-
-
0018836189
-
Peanut lectin binding properties of germinal centres of mouse lymphoid tissue
-
Rose, M. L., Birbeck, M. S., Wallis, V. J., Forrester, J. A. and Davies, A. J. (1980) Peanut lectin binding properties of germinal centres of mouse lymphoid tissue. Nature 284, 364-366.
-
(1980)
Nature
, vol.284
, pp. 364-366
-
-
Rose, M.L.1
Birbeck, M.S.2
Wallis, V.J.3
Forrester, J.A.4
Davies, A.J.5
-
33
-
-
0028983890
-
The E-mu-bcl-2 transgene enhances antigen-induced germinal center formation in both BALB/c and SJL mice but causes age-dependent germinal center hyperplasia only in the lymphoma-prone SJL strain
-
Secord, E. A., Edington, J. M. and Thorbecke, G. J. (1995) The E-mu-bcl-2 transgene enhances antigen-induced germinal center formation in both BALB/c and SJL mice but causes age-dependent germinal center hyperplasia only in the lymphoma-prone SJL strain. Am. J. Pathol. 147, 422-433.
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 422-433
-
-
Secord, E.A.1
Edington, J.M.2
Thorbecke, G.J.3
-
34
-
-
0029014435
-
Antigen-induced B-cell death and elimination during germinal-centre responses
-
Shokat, K. M. and Goodnow, C. C. (1995) Antigen-induced B-cell death and elimination during germinal-centre responses. Nature 375, 334-338.
-
(1995)
Nature
, vol.375
, pp. 334-338
-
-
Shokat, K.M.1
Goodnow, C.C.2
-
35
-
-
0024341521
-
Hybrid DNA arifact from PCR of closely related target sequences
-
Shuldiner, A. R., Nirula, A. and Roth, J. (1989) Hybrid DNA arifact from PCR of closely related target sequences. Nucl. Acids Res. 17, 4409.
-
(1989)
Nucl. Acids Res.
, vol.17
, pp. 4409
-
-
Shuldiner, A.R.1
Nirula, A.2
Roth, J.3
-
36
-
-
0029947265
-
Di-and tri-nucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells
-
Smith, D. S., Creadon, G., Jena, P. K., Portanova, J. P., Kotzin, B. L. and Wysocki, L. J. (1996) Di-and tri-nucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells. J. Immunol. 156, 2642-2652.
-
(1996)
J. Immunol.
, vol.156
, pp. 2642-2652
-
-
Smith, D.S.1
Creadon, G.2
Jena, P.K.3
Portanova, J.P.4
Kotzin, B.L.5
Wysocki, L.J.6
-
37
-
-
0028675668
-
Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers
-
Smith, K. G. C., Weiss, U., Rajewsky, K., Nossal, G. J. and Tarlington, D. M. (1995) Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers. Immunity 1, 803-813.
-
(1995)
Immunity
, vol.1
, pp. 803-813
-
-
Smith, K.G.C.1
Weiss, U.2
Rajewsky, K.3
Nossal, G.J.4
Tarlington, D.M.5
-
38
-
-
0025226018
-
Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice
-
Strasser, A., Harris, A. W., Vaux, D. L., Webb, E., Bath, M. L., Adams, J. M. and Cory, S. (1990) Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice. Curr. Top. Micro. Immunol. 166, 175-181.
-
(1990)
Curr. Top. Micro. Immunol.
, vol.166
, pp. 175-181
-
-
Strasser, A.1
Harris, A.W.2
Vaux, D.L.3
Webb, E.4
Bath, M.L.5
Adams, J.M.6
Cory, S.7
-
39
-
-
0025939204
-
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
-
Strasser, A., Whittingham, S., Vaux, D., Bath, M. L., Adams, J. M., Cory, S. and Harris, A. (1991) Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proc. Natl. Acad. Sci. U.S.A. 88, 8661-8665.
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 8661-8665
-
-
Strasser, A.1
Whittingham, S.2
Vaux, D.3
Bath, M.L.4
Adams, J.M.5
Cory, S.6
Harris, A.7
-
40
-
-
0027427492
-
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
-
Veis, D. J., Sorenson, C. M., Shutter, J. R. and Korsmeyer, S. J. (1993) Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75, 229-240.
-
(1993)
Cell
, vol.75
, pp. 229-240
-
-
Veis, D.J.1
Sorenson, C.M.2
Shutter, J.R.3
Korsmeyer, S.J.4
-
41
-
-
0026470596
-
What limits affinity maturation of antibodies in Xenopus-the rate of somatic mutation or the ability to select mutatants?
-
Wilson, M., Hasu, E., Marcuz, A, Courtet, M., DuPasquier, L. and Steinberg, C. (1992) What limits affinity maturation of antibodies in Xenopus-the rate of somatic mutation or the ability to select mutatants? EMBO J. 11, 4337-4347.
-
(1992)
EMBO J.
, vol.11
, pp. 4337-4347
-
-
Wilson, M.1
Hasu, E.2
Marcuz, A.3
Courtet, M.4
DuPasquier, L.5
Steinberg, C.6
|