Amiodarone induced lipidosis similar to Niemann-Pick C disease. Biochemical and morphological study

Life Sciences

Volumn 57, Issue 21, 1995, Pages 1963-1971

  Palmeri, S ^a   Battisti, C ^a,b   Malandrini, A ^a   Federico, A ^a,b  

^a UNIVERSITY OF SIENA   (Italy)

^b Associazione Anni Verdi   (Italy)

Author keywords

amiodarone; cholesterol metabolism; induced lipidosis; Niemann Pick C disease; sphingomyelinase activity

Indexed keywords

AMIODARONE; CHOLESTEROL; FILIPIN; HYDROLASE; LYSOSOME ENZYME; MEMBRANE LIPID; SPHINGOMYELIN PHOSPHODIESTERASE;

ARTICLE; CELL CULTURE; CELL INCLUSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOCHEMISTRY; HUMAN; HUMAN CELL; LIPID BILAYER; LIPIDOSIS; LYSOSOME; NIEMANN PICK DISEASE; SKIN FIBROBLAST; ULTRASTRUCTURE;

AMIODARONE; CELLS, CULTURED; CHOLESTEROL; CULTURE MEDIA; FIBROBLASTS; HUMAN; HYDROLASES; KINETICS; LIPOIDOSIS; LYSOSOMES; NIEMANN-PICK DISEASES; SPHINGOMYELIN PHOSPHODIESTERASE; SUPPORT, NON-U.S. GOV'T;

EID: 0028863121     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/0024-3205(95)02129-7     Document Type: Article

References (33)

1. Deficiency of sphingomyelin-cleaving enzyme activity in tissue cultures derived from patients with Niemann-Pick disease