Tumor gene targeting using microspheres: Cell culture and in vivo studies

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 4, Issue 4, 1997, Pages 263-267

  Dass, Crispin R ^a   DeCruz, E E ^a   Walker, T L ^a   Burton, M A ^a  

^a CHARLES STURT UNIVERSITY   (Australia)

Author keywords

Cancer; Cell; Expression; Gene; Gene delivery; Micro sphere

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; HYDROXYAPATITE; MICROSPHERE; PLASMID DNA; POLYSTYRENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA TRANSFECTION; GENE TARGETING; KIDNEY TUMOR; NONHUMAN; PLASMID; PRIORITY JOURNAL; RAT;

EID: 0031415821     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.3109/10717549709052012     Document Type: Article

References (17)

1. Alexakis, T., Boadi, D. K., Quong, D., Groboillot, A., O'Neill, I., Poncelet, D., and Neufeld, R. J. 1995. Microencapsulation of DNA within alginate microspheres and cross-linked chitosan membranes for in vivo application. Appl. Biochem. Biotechnol. 50:93-106.
2. Bertling, W. M., Gareis, M., Paspaleeva, V., Zimmer, A., Kreuter, J., Nurnberg, E., and Harrer, P. 1991. Use of liposomes, viral capsids, and nanoparticles as DNA carriers. Biotechnol Appl Biochem. 13:390-405.
3. Boucher, R. C. 1996. Current status of CF gene therapy. Trends Genet. 12:81-84.
4. 2+ and von Willebrand factor release in human endothelial cells. Am. J. Pathol. 138:213-221.
5. Dass, C. R., Walker, T. L., Burton, M. A., and DeCruz, E. E. 1997. Cationic liposomes and gene therapy for solid tumors. Drug Delivery 4:151-166.
6. Dass, C. R., Walker, T. L., DeCruz, E. E., and Burton, M. A. 1996. In-vitro evaluation of ion-exchange microspheres as carriers for plasmid DNA. Pharm. Sci. 2:401-405.
7. Fasbender, A. J., Zabner, J., and Welsh, M. J. 1995. Optimization of cationic lipid-mediated gene transfer to airway epithelia. Am. J. Physiol. 269:L45-L51.
8. Gray, B. N., Burton, M. A., Kelleher, D. K., Anderson, J., and Klemp, P. 1989. Selective internal radiation (SIR) therapy for treatment of liver metastases: Measurement of response rate. J. Surg. Oncol. 42:192-196.
9. Grubb, B. R., Pickles, R. J., Ye, H., Yankaskas, J. R., Vick, R. N., Engelhardt, J. F., Wilson, J. M., Johnson, L. G., and Boucher, R. C. 1994. Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans. Nature 371:802-806.
10. Jain, R. K. 1996. 1995 Whitaker Lecture: Delivery of molecules, particles, and cells to solid tumours. Ann. Biomed. Eng. 24:457-473.
11. Meade, V. M., Burton, M. A., Gray, B. N., and Self, G. W. 1987. Distribution of different sized microspheres in experimental hepatic tumours. Eur. J. Cancer Clin. Oncol. 23:37-41.
12. Murray, J. C., and Carmichael, J. 1995. Targeting solid tumours: Challenges, disappointments, and opportunities. Adv. Drug Delivery Rev. 17:117-127.
13. Napoli, S., Burton, M. A., Martins, I. J., Chen, Y., Codde, J. P., and Gray, B. N. 1992. Dose response and toxicity of doxorubicin microspheres in a rat tumour model. Anticancer Drugs 3:47-53.
14. Nishi, T., Yoshizato, K., Yamashiro, S., Takeshima, H., Sato, K., Hamada, K., Kitamura, I., Yoshimura, T., Saya, H., Kuratsu, J., and Ushio, Y. 1996. High-efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in vivo electroporation. Cancer Res. 56:1050-1055.
15. Symonds, G., Sun, L. Q., and Gerlach, W. 1995. Ribozyme and antisense constructs confer resistance to HIV-1 infection in T lymphocyte cells. Microbiol. Aust. 16:symposium 39.3.
16. Walker, T. L., White, J. D., Esdale, W. J., Burton, M. A., and DeCruz, E. E. 1996. Tumour cells surviving in vivo cisplatin chemotherapy display elevated c-myc expression. Br. J. Cancer 73:610-614.
17. Zhao, Q., Song, X., Waldschmidt, T., Fisher, E., and Krieg, A. M. 1996. Oligonucleotide uptake in human hematopoietic cells is increased in leukemia and is related to cellular activation. Blood 88:1788-1795.