A roadmap for HLA-DR peptide binding specificities

Human Immunology

Volumn 58, Issue 2, 1997, Pages 61-69

  Chelvanayagam, Gareth ^a  

^a Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

AMINO ACID SEQUENCE; ANTIGEN BINDING; ARTICLE; CRYSTAL STRUCTURE; HLA SYSTEM; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN BINDING; SEQUENCE HOMOLOGY;

ALLELES; ANTIBODY SPECIFICITY; BINDING SITES; GENES, MHC CLASS II; HLA-DR ANTIGENS; PEPTIDE MAPPING; PEPTIDES; PROTEIN CONFORMATION;

EID: 0031409658     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(97)00185-7     Document Type: Article

References (40)

1. Townsend A, Bodmer H. Antigen recognition by class I-restricted T lymphocytes. Annu Rev Immunol. 7:1989;601-624.
2. Cresswell P. Getting peptides into MHC class II molecules. Curr Biol. 4:1994;541-543.
3. Bjorkman PJ, Burmeister WP. Structures of two classes of MHC molecules elucidated crucial differences and similarities . Curr Opin Str Biol. 4:1994;852-856.
4. Bjorkman PJ, Saper MA, Samraoui B, Bennett WS, Strominger JL, Wiley DC. Structure of the human class I histocompatibility antigen HLA-A2. Nature. 329:1987;506-511.
5. Chelvanayagam G, Apostolopoulos V, McKenzie IFC. Milestones in the molecular structure of the major histocompatibility complex. Prot Eng. 10:1997;471-474.
6. Stern LJ, Brown JH, Jardetzky TS, Gorga JC, Urban RG, Strominger JL, Wiley DC. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature. 368:1994;215-221.
7. Ghosh P, Amaya M, Mellins E, Wiley DC. The structure of an intermediate in class II MHC matiuration CLIP bound to HLA-DR3 . Nature. 378:1995;457-462.
8. Fremont DH, Hendrickson WA, Marrack P, Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science. 272:1996;1001-1004.
9. Garrett TP, Saper MA, Bjorkman PJ, Strominger JL, Wiley DC. Specificity pockets for the side chains of peptide antigens in HLA-Aw68. Nature. 342:1989;692-696.
10. Saper MA, Bjorkman PJ, Wiley DC. Refined structure of the human histocompatibility antigen HLA-A2 at 2 6Å resolution . J Mol Biol. 219:1991;277-319.
11. Matsumura M, Fremont D, Peterson PA, Wilson IA. Emerging principles for the recognition of peptide antigens by MHC class I molecules. Science. 257:1992;927-935.
12. Falk K, Rötzschke O, Stevanovi'c S, Jung G, Rammensee H-G. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature. 351:1991;290-296.
13. Jardetzky TS, Lane WS, Robinson RA, Madden DR, Wiley DC. Identification of self peptides bound to purified HLA-B27. Nature. 353:1991;326-329.
14. Hunt DF, Henderson RA, Shabanowitz J, Sakaguchi K, Michel H, Sevilir N, Cox AL, Appella E, Engelhard VH. Characterisation of peptides bound to the class I MHC molecule HLA-A2 1 by mass spectrometry . Science. 255:1992;1261-1263.
15. Rammensee H-G, Friede T, Stevanovi'c S. MHC ligands and peptide motifs First listing . Immunogenetics. 41:1995;178-228.
16. Chelvanayagam G. A roadmap for HLA-A, HLA-B and HLA-C peptide binding specificities. Immunogenetics. 45:1996;15-26.
17. Newell WR, Trowsdale J, Beck S. MHCDB Database of the human MHC (release 2) . Immunogenetics. 45:1996;6-8.
18. Kobayashi H, Kokubo T, Abe Y, Sato K, Kimura S, Miyokawa N, Katagiri M. Analysis of anchor residues in a naturally processed HLA-DR53 ligand. Immunogenetics. 44:1996;366-371.
19. Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 364:1993;33-39.
20. Garboczi DN, Ghosh P, Utz U, Fan QR, Biddison WE, Wiley DC. Structure of the complex between human T-cell receptore, viral peptide and HLA-A2. Nature. 384:1996;134-141.
21. Reay PA, Kantor RM, Davis MM. Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochorm c (93-101). J Immunol. 152:1994;3946-3957.
22. Schild H, Gruneberg U, Pougialis G, Wallny HJ, Keilholz W, Stevanovi'c S, Rammensee H-G. Natural ligand motifs of H2_E molecules are allele specific and illustrate homology to HLA-DR molecules. Int Immunol. 7:1995;1957-1965.
23. Hsu BL, Evavold BD, Allen PM. Modulation of T cell development by an endogenous altered peptide ligand. J Exp Med. 181:1996;805-810.
24. Evavold BD, Sloan-Lancaster J, Hsu BL, Allen PM. Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides. J Immunol. 150:1993;3131-3140.
25. Spain LM, Jorgensen JL, Davis MM, Berg LJ. A peptide antigen antagonist prevents the differentiation of T cell receptor transgenic thymocytes. J Immunol. 152:1994;1709-1717.
26. Vogt AB, Kropshofe H, Kalbacher H, Kalbus M, Rammensee H-G, Coligan JE, Martin R. Ligand motifs of HLA-DRB*0101 and DRB1*1501 molecules deliniated from self-peptides. J Immunol. 153:1994;1665-1673.
27. Wucherpfennig KW, Sette A, Southwood S, Oseroff C, Matsui M, Strominger JL, Hafler DA. Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones. J Exp Med. 179:1994;279-290.
28. Falk K, Rötzschke O, Stevanovi'c S, Jung G, Rammensee H-G. Pool sequencing of natural HLA-DR, DQ and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules. Immunogenetics. 39:1994;230-242.
29. Wolf PR, Ploegh HL. DM exchange mechanism. Nature. 376:1995;464-465.
30. Boitel B, Blank U, Mége D, Corradin G, Sidney J, Sette A, Acuto O. Strong similarities in fine specificity amoung DRB1*1302-restricted tetanus toxin tt830-834-specific TCRs in spite of highly heterogeneous CDR3. J Immunol. 154:1995;3245-3255.
31. Davenport MP, Quinn CL, Chicz RM, Green BW, Willis AC, Lane WS, Bell JI, Hill AV. Naturally processed peptides from two disease-resistance associated HLA-DR13 alleles show related sequence motifs and the effects of the dimorphism at position 86 of the HLA-DRβ chain. Proc Natl Acad Sci USA. 92:1995;6567-6571.
32. Davenport MP, Quinn C., Valsasnini P, Sinigaglia F, Hill AVS, Bell JI. Analysis of peptide-binding motifs for two disease associate HLA-DR13 alleles using an M13 phage display library. Immunology. 88:1996;482-486.
33. Geluk A, van Meijgaarden KE, Southwood S, Oseroff C, Drijfhout JW, de Vries RRP, Ottenhoff THM, Sette A. HLA-DR3 molecules can bind peptides carrying two alternative specific submotifs. J Immunol. 152:1994;5742-5748.
34. Zeliszewski D, Dorval I, Golvano JJ, Prevost A, Borras-Cuesta F, Sterkers G. Sharing of four DR-β sequence motifs between HLA-DRB1*1601 and DRB1*1101 correlates with frequent degenerate T-cell recognition of HA306-320 peptide complexed to these two molecules. Scand J Immunol. 43:1996;146-154.
35. Wordsworth BP, Lanchbury JSS, Sakkas LI, Welsh KI, Panayi GS, Bell JI. HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region. Proc Natl Acad Sci USA. 86:1989;10049-10053.
36. Davenport MP, Godkin A, Friede T, Stevanovi'c S, Willis AC, Hill AVS, Rammensee H-G. A distinctive peptide binding motif for HLA-DRB1*0407, and HLA-DR4 subtype not associated with rheumatoid arthritis. Immunogenetics. 45:1997;229-232.
37. Madden DR. The three-dimensional structure of peptide-MHC complexes. Annu Rev Immunol. 13:1995;587-622.
38. Chelvanayagam G, Jakobsen IB, Gao X, Easteal S. Structural comparison of major histocompatibility complex class I molecules and homology modelling of five distinct human leukocyte antigen-A alleles. Prot Eng. 9:1996;1151-1164.
39. Smith KJ, Reid SW, Stuart DI, McMichael AJ, Jones EY, Bell JI. An altered position of the 2 helix of MHC class I is revealed by the crystal structure of HLAB-B*3501. Immunity. 4:1996a;203-214.
40. Smith KJ, Reid SW, Harlos K, McMichael AJ, Stuart DJ, Bell JI, Jones EY. Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53. Immunity. 4:1996b;215-228.