-
1
-
-
0025239673
-
Tamoxifen for breast cancer: Associated endometrial cancer
-
Gusberg, S.B. (1990) Tamoxifen for breast cancer: associated endometrial cancer. Cancer, 65, 1463-1464.
-
(1990)
Cancer
, vol.65
, pp. 1463-1464
-
-
Gusberg, S.B.1
-
2
-
-
0028208456
-
Endometrial cancer in tamoxifen-treated breast cancer patients: Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP)
-
Fisher, B., Constantino, J.P., Redmond, C.K., Fisher, E.R., Wickerham, D.L. and Cronin, W.M. (1994) Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP). J. Natl Cancer Inst., 86, 527-537.
-
(1994)
J. Natl Cancer Inst.
, vol.86
, pp. 527-537
-
-
Fisher, B.1
Constantino, J.P.2
Redmond, C.K.3
Fisher, E.R.4
Wickerham, D.L.5
Cronin, W.M.6
-
3
-
-
0028314903
-
Restating the risks of tamoxifen
-
Seachrist, L. (1994) Restating the risks of tamoxifen, Science, 263, 910-911.
-
(1994)
Science
, vol.263
, pp. 910-911
-
-
Seachrist, L.1
-
4
-
-
0028278172
-
Tamoxifen: Hanging in the balance
-
Marshall, E. (1994) Tamoxifen: hanging in the balance. Science, 264, 1524-1527
-
(1994)
Science
, vol.264
, pp. 1524-1527
-
-
Marshall, E.1
-
5
-
-
0028898873
-
Adjuvant tamoxifen therapy for early stage breast cancer and second primary malignancies
-
Rutqvist, L.E., Johansson, H., Signomklao, T., Johansson, U., Fornander, T. and Wilking, N. (1995) Adjuvant tamoxifen therapy for early stage breast cancer and second primary malignancies. J. Natl Cancer Inst., 87, 645-651.
-
(1995)
J. Natl Cancer Inst.
, vol.87
, pp. 645-651
-
-
Rutqvist, L.E.1
Johansson, H.2
Signomklao, T.3
Johansson, U.4
Fornander, T.5
Wilking, N.6
-
6
-
-
0024546736
-
Adjuvant tamoxifen in early breast cancer: Occurrence of new primary cancers
-
Fornander, T. et al. (1989) Adjuvant tamoxifen in early breast cancer: occurrence of new primary cancers. Lancet, i, 117-119.
-
(1989)
Lancet
, vol.1
, pp. 117-119
-
-
Fornander, T.1
-
7
-
-
0027201501
-
Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats
-
Greaves, P., Goonetilleke, R., Nunn, G, Topham, J. and Orton, T. (1993) Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats. Cancer Res., 53, 3919-3924.
-
(1993)
Cancer Res.
, vol.53
, pp. 3919-3924
-
-
Greaves, P.1
Goonetilleke, R.2
Nunn, G.3
Topham, J.4
Orton, T.5
-
8
-
-
0027428568
-
Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl:CD(BR) rats
-
Hard, G. Iatropoulos, M.J., Jordan, K., Radi, L., Kaltenberg, O.P., Imondi, A.R. and Williams, G.M. (1993) Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl:CD(BR) rats. Cancer Res., 53, 4534-4541.
-
(1993)
Cancer Res.
, vol.53
, pp. 4534-4541
-
-
Hard, G.1
Iatropoulos, M.J.2
Jordan, K.3
Radi, L.4
Kaltenberg, O.P.5
Imondi, A.R.6
Williams, G.M.7
-
9
-
-
0000151348
-
Tamoxifen
-
Laurence, D.R., McLean, A.E.M. and Weatherall, M. (eds). Academic Press, New York, NY
-
Tucker, M.J., Adam, H.K. and Patterson, J.S. (1984) Tamoxifen. In Laurence, D.R., McLean, A.E.M. and Weatherall, M. (eds), Safety Testing of New Drugs. Academic Press, New York, NY, pp. 125-161.
-
(1984)
Safety Testing of New Drugs
, pp. 125-161
-
-
Tucker, M.J.1
Adam, H.K.2
Patterson, J.S.3
-
10
-
-
33646292391
-
Comparative toxicology of droloxifene (3-OH tamoxifen) and tamoxifen: Hepatocellular carcinomas produced by tamoxifen
-
Abstract F18
-
Rattel, B., Löser, R., Dahmer, E.G., Liehn, H.D. and Seibel, K. (1987) Comparative toxicology of droloxifene (3-OH tamoxifen) and tamoxifen: hepatocellular carcinomas produced by tamoxifen. Proceedings of the Biennial International Breast Cancer Research Conference, Miami. Abstract F18.
-
(1987)
Proceedings of the Biennial International Breast Cancer Research Conference, Miami
-
-
Rattel, B.1
Löser, R.2
Dahmer, E.G.3
Liehn, H.D.4
Seibel, K.5
-
11
-
-
85061887192
-
Unlike tamoxifen, droloxifene produces no hepatic tumours in the rat
-
Dahmer, E. and Rattel, B. (1994) Unlike tamoxifen, droloxifene produces no hepatic tumours in the rat. Onkologie, 17, 6-16.
-
(1994)
Onkologie
, vol.17
, pp. 6-16
-
-
Dahmer, E.1
Rattel, B.2
-
12
-
-
0026906374
-
Long-term prophylactic used of tamoxifen: Is it safe?
-
Williams, G.M., Iatropoulos, M.J. and Hard, G.C. (1992) Long-term prophylactic used of tamoxifen: is it safe? Eur. J. Cancer Prevent., 1, 386-387.
-
(1992)
Eur. J. Cancer Prevent.
, vol.1
, pp. 386-387
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Hard, G.C.3
-
13
-
-
0027397629
-
Tamoxifen induces hepatocellular carcinoma in rat liver: A 1 year study with two antiestrogens
-
Hirsimaki, P., Hirsimaki, Y., Nieminen, L. and Payne, B.J. (1993) Tamoxifen induces hepatocellular carcinoma in rat liver: a 1 year study with two antiestrogens. Arch. Toxicol., 67, 49-54.
-
(1993)
Arch. Toxicol.
, vol.67
, pp. 49-54
-
-
Hirsimaki, P.1
Hirsimaki, Y.2
Nieminen, L.3
Payne, B.J.4
-
14
-
-
0024445141
-
Induction and promotion of gamma-glutamyltranspeptidase-positive foci in the liver of female rats treated with ethinyl estradiol, clomiphene, tamoxifen and their associations
-
Ghia, M. and Mereto, E. (1989) Induction and promotion of gamma-glutamyltranspeptidase-positive foci in the liver of female rats treated with ethinyl estradiol, clomiphene, tamoxifen and their associations. Cancer Lett., 46, 195-202.
-
(1989)
Cancer Lett.
, vol.46
, pp. 195-202
-
-
Ghia, M.1
Mereto, E.2
-
15
-
-
0023034379
-
Effects of ethinyl estradiol and tamoxifen on liver DNA turnover and new synthesis and appearance of gamma glutamyl transpeptidase-positive foci in female rats
-
Yager, J.D., Roebuck B.D., Paluszcyk, T.L. and Memoli, V.A.(1986) Effects of ethinyl estradiol and tamoxifen on liver DNA turnover and new synthesis and appearance of gamma glutamyl transpeptidase-positive foci in female rats. Carcinogenesis, 7, 2007-2014.
-
(1986)
Carcinogenesis
, vol.7
, pp. 2007-2014
-
-
Yager, J.D.1
Roebuck, B.D.2
Paluszcyk, T.L.3
Memoli, V.A.4
-
16
-
-
0026065862
-
Synthetic estrogens and tamoxiten as promoters of hepatocarcinogenesis
-
Yager, J.D. and Shi, Y.E. (1991) Synthetic estrogens and tamoxiten as promoters of hepatocarcinogenesis. Prevent. Med., 20, 27-37.
-
(1991)
Prevent. Med.
, vol.20
, pp. 27-37
-
-
Yager, J.D.1
Shi, Y.E.2
-
17
-
-
0028899660
-
Tamoxifen induces short-term cumulative DNA damage and liver tumors in rats: Promotion by phenobarbital
-
Carthew, P., Martin, E.A., White, I.N.H., De Matteis, F., Edwards, R.E., Dorman, B.M., Heydon, R.T. and Smith, L.L. (1995) Tamoxifen induces short-term cumulative DNA damage and liver tumors in rats: promotion by phenobarbital. Cancer Res., 55, 544-547.
-
(1995)
Cancer Res.
, vol.55
, pp. 544-547
-
-
Carthew, P.1
Martin, E.A.2
White, I.N.H.3
De Matteis, F.4
Edwards, R.E.5
Dorman, B.M.6
Heydon, R.T.7
Smith, L.L.8
-
18
-
-
0029052183
-
32P-postlabelling in three rat strains exposed to dietary tamoxifen: The relationship between cell proliferation and liver tumour formation
-
32P-postlabelling in three rat strains exposed to dietary tamoxifen: the relationship between cell proliferation and liver tumour formation. Carcinogenesis, 16, 1299-1304.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1299-1304
-
-
Cartnew, P.1
Rich, K.J.2
Martin, E.A.3
De Matteis, F.4
Lim, C.K.5
Manson, M.M.6
Festing, M.7
White, I.N.H.8
Smith, L.L.9
-
19
-
-
0011876884
-
Characterisation of tamoxifen induced DNA adducts formed in rat liver
-
abstract 811
-
Martin, E.A., Turtletaub, K.W., Heydon, R., Davies, A., White, I.N.H. and Smith, L.L. (1995) Characterisation of tamoxifen induced DNA adducts formed in rat liver. Toxicologist, 15, 152 (abstract 811).
-
(1995)
Toxicologist
, vol.15
, pp. 152
-
-
Martin, E.A.1
Turtletaub, K.W.2
Heydon, R.3
Davies, A.4
White, I.N.H.5
Smith, L.L.6
-
20
-
-
0026606580
-
Induction of covalent DNA adducts in rodents by tamoxifen
-
Han, X. and Liehr, J.G. (1990) Induction of covalent DNA adducts in rodents by tamoxifen. Cancer Res., 52, 1360-1363.
-
(1990)
Cancer Res.
, vol.52
, pp. 1360-1363
-
-
Han, X.1
Liehr, J.G.2
-
21
-
-
0027054733
-
Genotoxic potential of tamoxifen and analogues in female Fischer F344/N rats, DBA/2 and C57B1/6 mice and in human MCL-5 cells
-
White, I.N.H., De Matteis, F., Davies, A., Smith, L.L., Crofton-Sleigh, C., Venitt, S., Hewer, A. and Phillips, D.H. (1993) Genotoxic potential of tamoxifen and analogues in female Fischer F344/N rats, DBA/2 and C57B1/6 mice and in human MCL-5 cells. Carcinogenesis, 13, 2197-2203.
-
(1993)
Carcinogenesis
, vol.13
, pp. 2197-2203
-
-
White, I.N.H.1
De Matteis, F.2
Davies, A.3
Smith, L.L.4
Crofton-Sleigh, C.5
Venitt, S.6
Hewer, A.7
Phillips, D.H.8
-
22
-
-
0028979270
-
32P-Postlabelled DNA adducts in liver obtained from women treated with tamoxifen
-
32P-Postlabelled DNA adducts in liver obtained from women treated with tamoxifen. Carcinogenesis, 16, 1651-1654.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1651-1654
-
-
Martin, E.A.1
Rich, K.2
White, I.N.H.3
Woods, K.L.4
Powles, T.J.5
Smith, L.L.6
-
23
-
-
0026319776
-
Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: Possible involvement of flavin-containing monooxygenases in tamoxifen activation
-
Mani, C. and Kupfer, D. (1991) Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: possible involvement of flavin-containing monooxygenases in tamoxifen activation. Cancer Res., 51, 6052-6058.
-
(1991)
Cancer Res.
, vol.51
, pp. 6052-6058
-
-
Mani, C.1
Kupfer, D.2
-
24
-
-
0028035492
-
Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s
-
Styles, J.A., Davies, A., Lim, C.K., De Matteis, F., Stanley, L.A., White, I.N.H., Yuan, Z.-X. and Smith, L.L. (1994) Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s. Carcinogenesis, 15, 5-9.
-
(1994)
Carcinogenesis
, vol.15
, pp. 5-9
-
-
Styles, J.A.1
Davies, A.2
Lim, C.K.3
De Matteis, F.4
Stanley, L.A.5
White, I.N.H.6
Yuan, Z.-X.7
Smith, L.L.8
-
25
-
-
0027217202
-
Micronucleus assays using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochromes P-450 and microsomal epoxide hydrolase
-
Crofton-Sleigh, C., Doherty, A., Ellard, S., Parry, E.M. and Venitt, S. (1993) Micronucleus assays using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochromes P-450 and microsomal epoxide hydrolase. Mutagenesis, 8, 363-372.
-
(1993)
Mutagenesis
, vol.8
, pp. 363-372
-
-
Crofton-Sleigh, C.1
Doherty, A.2
Ellard, S.3
Parry, E.M.4
Venitt, S.5
-
26
-
-
0028233205
-
Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats
-
Sargent, L.M., Dragan, Y.P., Bahnub, N., Wiley, J.E., Sattler, C., Schroeder, P., Sattler, G.L., Jordan, V.C. and Pitot, H.C. (1994) Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats. Cancer Res., 54, 3357-3360.
-
(1994)
Cancer Res.
, vol.54
, pp. 3357-3360
-
-
Sargent, L.M.1
Dragan, Y.P.2
Bahnub, N.3
Wiley, J.E.4
Sattler, C.5
Schroeder, P.6
Sattler, G.L.7
Jordan, V.C.8
Pitot, H.C.9
-
27
-
-
2642629512
-
Comparison of clastogenic effects induced in rats by tamoxifen and some of its analogues
-
abstract 432
-
Styles, J.A., Davies, R. and Smith, L.L.(1995) Comparison of clastogenic effects induced in rats by tamoxifen and some of its analogues. Toxicologist, 15, 82 (abstract 432).
-
(1995)
Toxicologist
, vol.15
, pp. 82
-
-
Styles, J.A.1
Davies, R.2
Smith, L.L.3
-
28
-
-
15844385780
-
Induction of hepatic aneuploidy in vivo by tamoxifen, toremifene and idoxifene in female Sprague-Dawley rats
-
Sargent, L.M. et al. (1996) Induction of hepatic aneuploidy in vivo by tamoxifen, toremifene and idoxifene in female Sprague-Dawley rats. Carcinogenesis, 17, 1051-1056.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1051-1056
-
-
Sargent, L.M.1
-
29
-
-
74049159447
-
Tamoxifen causes somatic gene mutations, DNA adducts and hyperplasia in the livers of Big Blue transgenic F344 rats
-
abstract 823
-
Styles, J.A., Davies, R., Martin, E.A., White, I.N.H. and Smith, L.L. (1996) Tamoxifen causes somatic gene mutations, DNA adducts and hyperplasia in the livers of Big Blue transgenic F344 rats. Toxicologist, 30, 161 (abstract 823).
-
(1996)
Toxicologist
, vol.30
, pp. 161
-
-
Styles, J.A.1
Davies, R.2
Martin, E.A.3
White, I.N.H.4
Smith, L.L.5
-
30
-
-
0028177045
-
A comparative study of tamoxifen metabolism in female rat, mouse and human liver microsomes
-
Lim, C.K., Yuan, Z.-X., Lamb, J.H., White, I.N.H., De Matteis, F. and Smith, L.L. (1994) A comparative study of tamoxifen metabolism in female rat, mouse and human liver microsomes. Carcinogenesis, 15, 589-593.
-
(1994)
Carcinogenesis
, vol.15
, pp. 589-593
-
-
Lim, C.K.1
Yuan, Z.-X.2
Lamb, J.H.3
White, I.N.H.4
De Matteis, F.5
Smith, L.L.6
-
31
-
-
0027409546
-
Multicenter phase II efficacy trial of toremifene in tamoxifen-refractory patients with advanced breast cancer
-
Vogel, C.L., Shemano, I., Schoenfelder, J., Gams, R.A. and Green, M.R. (1993) Multicenter phase II efficacy trial of toremifene in tamoxifen-refractory patients with advanced breast cancer. J. Clin. Oncol., 11, 345-350.
-
(1993)
J. Clin. Oncol.
, vol.11
, pp. 345-350
-
-
Vogel, C.L.1
Shemano, I.2
Schoenfelder, J.3
Gams, R.A.4
Green, M.R.5
-
32
-
-
0023913406
-
Toremifene, a new antiestrogenic compound for treatment of advanced breast cancer. Phase II study
-
Valavaara, R. et al. (1988) Toremifene, a new antiestrogenic compound for treatment of advanced breast cancer. Phase II study. Eur. J. Cancer Clin. Oncol., 24, 785-790.
-
(1988)
Eur. J. Cancer Clin. Oncol.
, vol.24
, pp. 785-790
-
-
Valavaara, R.1
-
33
-
-
0002176924
-
Metaphase chromosome aberration assays in vitro
-
Kirkland, D.J. et al. (eds). Cambridge University Press, Cambridge, UK
-
Scott, D., Danford, N., Dean, B.J. and Kirkland, D. (1990) Metaphase chromosome aberration assays in vitro. In Kirkland, D.J. et al. (eds) Basic Mutagenicity Tests: UKEMS Recommended Procedures. UKEMS Subcommittee on Guidelines for Mutagenicity Testing Report. Part I Revised. Cambridge University Press, Cambridge, UK, pp. 62-86.
-
(1990)
Basic Mutagenicity Tests: UKEMS Recommended Procedures. UKEMS Subcommittee on Guidelines for Mutagenicity Testing Report. Part I Revised
, pp. 62-86
-
-
Scott, D.1
Danford, N.2
Dean, B.J.3
Kirkland, D.4
-
34
-
-
0023102433
-
The induction of aneuploidy by nitrogen mustard in a human lymphoblastoid cell line
-
Crespi, C.L, Sierras, G.M. and Penman, B.O.W. (1987) The induction of aneuploidy by nitrogen mustard in a human lymphoblastoid cell line. Mutat. Res., 190, 69-76.
-
(1987)
Mutat. Res.
, vol.190
, pp. 69-76
-
-
Crespi, C.L.1
Sierras, G.M.2
Penman, B.O.W.3
-
35
-
-
0020321538
-
Spreading and staining of human metaphase chromosomes on aminoalkysilane-treated glass slides
-
Van Prooijen-Knegt, A.C. et al. (1982) Spreading and staining of human metaphase chromosomes on aminoalkysilane-treated glass slides. Histochem. J., 14, 333-344.
-
(1982)
Histochem. J.
, vol.14
, pp. 333-344
-
-
Van Prooijen-Knegt, A.C.1
-
37
-
-
2642636687
-
Oestrogens, progestins and combinations
-
IARC Monographs (1987) Oestrogens, progestins and combinations. IARC Monogr., 7, 273-278.
-
(1987)
IARC Monogr.
, vol.7
, pp. 273-278
-
-
-
38
-
-
0024834314
-
Progression: The terminal stage in carcinogenesis
-
Pitot, H. (1989) Progression: the terminal stage in carcinogenesis. Jpn. J. Cancer Res., 80, 599-607.
-
(1989)
Jpn. J. Cancer Res.
, vol.80
, pp. 599-607
-
-
Pitot, H.1
-
39
-
-
0026342683
-
Structural requirements for the in vitro transformation of Syrian hamster embryo cells by stilbene estrogens and triphenylethylene-type antiestrogens
-
Metzler, M. and Schiffmann, D. (1991) Structural requirements for the in vitro transformation of Syrian hamster embryo cells by stilbene estrogens and triphenylethylene-type antiestrogens. Am. J. Clin. Oncol., 14 (suppl. 2), 30-35.
-
(1991)
Am. J. Clin. Oncol.
, vol.14
, Issue.2 SUPPL.
, pp. 30-35
-
-
Metzler, M.1
Schiffmann, D.2
-
40
-
-
0022871361
-
Cytogenetic effects of a novel antiestrogen toremifene FC-1157a: A comparison with diethylstilbestrol and tamoxifen
-
Kärki, N.T. and Kärki, T. (1986) Cytogenetic effects of a novel antiestrogen toremifene FC-1157a: a comparison with diethylstilbestrol and tamoxifen. Arch. Toxicol., suppl. 9, 291.
-
(1986)
Arch. Toxicol., Suppl.
, vol.9
, pp. 291
-
-
Kärki, N.T.1
Kärki, T.2
-
41
-
-
0025931826
-
Mitogenesis, mutagenesis and animal cancer tests
-
Butterworth, B.E., Slaga, T.J., Farland, W. and McClain, M. (eds). Wiley-Liss, New York, NY
-
Ames, B.N. and Gold, L.S. (1991) Mitogenesis, mutagenesis and animal cancer tests. In Butterworth, B.E., Slaga, T.J., Farland, W. and McClain, M. (eds), Chemically Induced Cell Proliferation: Implications for Risk Assessment. Wiley-Liss, New York, NY, pp. 1-20.
-
(1991)
Chemically Induced Cell Proliferation: Implications for Risk Assessment
, pp. 1-20
-
-
Ames, B.N.1
Gold, L.S.2
-
42
-
-
0025168534
-
Cell proliferation in carcinogenesis
-
Cohen, S.M. and Ellwein, L.B. (1990) Cell proliferation in carcinogenesis. Science, 249, 1007-1011.
-
(1990)
Science
, vol.249
, pp. 1007-1011
-
-
Cohen, S.M.1
Ellwein, L.B.2
-
43
-
-
0028172454
-
32P-postlabelling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNa adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite
-
32P-postlabelling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite. Carcinogenesis, 15, 2087-2094.
-
(1994)
Carcinogenesis
, vol.15
, pp. 2087-2094
-
-
Randerath, K.1
Moorthy, B.2
Mabon, N.3
Sriram, P.4
|