Effect of sofalcone on the expression of hepatocyte growth factor (HGF) and a brief review of HGF in the stomach

Journal of Clinical Gastroenterology

Volumn 25, Issue SUPPL. 1, 1997, Pages

  Takahashi, Morio ^a   Hata, Yasuo ^a   Terano, Akira ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b DOKKYO UNIVERSITY   (Japan)

Author keywords

Gastric epithelial cell; Gastric fibroblast; Hepatocyte growth factor; Prostaglandin; Sofalcone

Indexed keywords

ANTIULCER AGENT; DIMETHYL SULFOXIDE; INDOMETACIN; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; PROSTAGLANDIN E1; PROSTAGLANDIN E2; SCATTER FACTOR; SOFALCONE;

ADULT; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; FIBROBLAST; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; STOMACH EPITHELIUM; STOMACH MUCOSA; STOMACH ULCER; ULCER HEALING;

ANTI-ULCER AGENTS; CELL DIVISION; CELLS, CULTURED; CHALCONE; CHALCONES; DINOPROSTONE; FIBROBLASTS; GASTRIC MUCOSA; HEPATOCYTE GROWTH FACTOR; HUMANS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-MET; RNA, MESSENGER; STOMACH ULCER;

EID: 0031405277     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004836-199700001-00006     Document Type: Conference Paper

References (41)

1. Rutten MJ, Harmon P, Campbell DR. Insulin enhances epidermal growth factor- and transforming growth factor alpha-stimulated growth in primary cultures of guinea pig gastric mucous epithelial cells. Scand J Gastroenterol 1991;26:965-73.
2. Chen MC, Lee AT, Soll AH. Mitogenic response of canine fundic epithelial cells in short-term culture to transforming growth factor α and insulin-like growth factor 1. J Clin Invest 1991;87:1716-23.
3. Rutten MJ, Dempsey PJ, Solomon TE, Coffey JRJ. TGF-α is a potent mitogen for primary cultures of guinea pig gastric mucous epithelial cells. Am J Physiol 1993;265:G361-9.
4. Yoshiura K, Ota S, Terano A, et al. Growth regulation of rabbit gastric epithelial cells and protooncogene expression. Dig Dis Sci 1994;39:1454-63.
5. Polk WH Jr, Dempsey PJ, Russell WE, et al. Increased production of transforming growth factor α following acute gastric injury. Gastroenterology 1992;102:1467-74.
6. Beauchamp RD, Barnard JA, MacCuthen CM, Cherner JA, Coffey RJ. Localization of transforming growth factor alpha and its receptor in gastric mucosal cells. Implications for a regulatory role in acid secretion and mucosal renewal. J Clin Invest 1989;83:1017-23.
7. Folkman J, Szabo S, Vattay P. Effect of oral administration of bFGF on healing of chronic duodenal ulcers, gastric secretion and acute mucosal lesions in rats. Gastroenterology 1990;98: 45.
8. Szabo S, Vattay P, Morales RE. Orally administered FGF mutein: effect on healing of chronic duodenal ulcers in rats. Dig Dis Sci 1989;34:1323.
9. Folkman J, Szabo S, Stovroff M, MacNeil P, Li W, Shing Y. Duodenal ulcer. Discovery of a new mechanism and development of angiogenic therapy that accelerates healing. Ann Surg 1991;214:414-27.
10. Morris GP, Wallace JL. The roles of ethanol and of acid in the production of gastric erosions in rats. Virchows Arch [B] 1981;38:23-8.
11. Lacy ER, Ito S. Rapid epithelial restitution of the rat gastric mucosa after ethanol injury. Lab Invest 1984;51:573-83.
12. Wang JY, Johnson LR. Induction of gastric and duodenal mucosal ornithine decarboxylase during stress. Am J Physiol 1989;257:G259-65.
13. Silen W. Gastric mucosal defence and repair. In: Johnson LR, ed. Physiology of the gastrointestinal tract. 2nd ed. New York: Raven Press, 1983;1055-69.
14. Rutten MJ, Ito S. Morphology and electrophysiology of guinea pig gastric mucosal repair in vitro. Am J Physiol 1983; 257:G171-83.
15. Silen W, Ito S. Mechanisms for rapid re-epithelialization of the gastric mucosal surface. Annu Rev Physiol 1985;47:217-29.
16. Yeomans ND, John DJBS, Deboer WG. Regeneration of gastric mucosa after aspirin-induced injury to the rat. Am J Dig Dis 1973;18:773-80.
17. Naldini L, Weidner KM, Vigna E, et al. Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J 1991;10:2867-78.
18. DiRenzo MF, Narsimhan RP, Olivero M, et al. Expression of the Met/HGF receptor in normal and neoplastic human tissues. Oncogene 1991;6:1997-2003.
19. Takahashi M, Ota S, Terano A, et al. Hepatocyte growth factor induces mitogenic reaction to the rabbit gastric epithelial cells in primary culture. Biochem Biophys Res Commun 1993;191:528-34.
20. Nakamura T. Structure and function of hepatocyte growth factor. Prog Growth Factor Res 1991;3:67-85.
21. Matsumoto K, Nakamura T. Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions. Crit Rev Oncogenesis 1992;3:27-54.
22. Igawa T, Kanda S, Kanetake H. Hepatocyte growth factor is a potent mitogen for cultured rabbit renal tubular epithelial cells. Biochem Biophys Res Commun 1991;174:831-8.
23. Matsumoto K, Tajima H, Nakamura T. Hepatocyte growth factor is a potent stimulator for human melanocytes. Biochem Biophys Res Commun 1991;176:45-51.
24. Matsumoto K, Yoshikawa K, Nakamura T. Marked stimulation of growth and motility of human keratinocytes by hepatocyte growth factor. Exp Cell Res 1991;196:114-20.
25. Kinoshita T, Tashiro K, Nakamura T. Marked increase of HGF mRNA in non-parenchymal liver cells of rats treated with hepatotoxins. Biochem Biophys Res Commun 1989;165: 1229-34.
26. Noji S, Tashiro K, Koyama E, et al. Expression of hepatocyte growth factor gene in endothelial and Kupffer cells of damaged rat liver, as revealed by in situ hybridization. Biochem Biophys Res Commun 1990;173:42-7.
27. Takahashi M, Ota S, Shimada T, et al. Hepatocyte growth factor is the most potent endogenous stimulant of rabbit gastric epithelial cell proliferation and migration in primary culture. J Clin Invest 1995;95:1994-2003.
28. Fukamachi H, Ichinose M, Tsukuda S, et al. Hepatocyte growth factor region specifically stimulates gastro-intestinal epithelial growth in primary culture. Biochem Biophys Res Commun 1994;205:1445-51.
29. Watanabe S, Hirose M, Wang X-E, et al. Hepatocyte growth factor accelerates the wound repair of cultured gastric mucosal cells. Biochem Biophys Res Commun 1994;199:1453-60.
30. Tsuji S, Kawano S, Tsujii M, Fusamoto H, Kamada T. Roles of hepatocyte growth factor and its receptor in gastric mucosa. A cell biological and molecular biological study. Dig Dis Sci 1995;40:1132-9.
31. Brinkmann V, Foroutan H, Sachs M, Weidner KM, Birchmeier W. Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells. J Cell Biol 1995;131:1573-86.
32. Kinoshita Y, Nakata H, Hassan S, et al. Gene expression of keratinocyte and hepatocyte growth factors during the healing of rat gastric mucosal lesions. Gastroenterology 1995;109: 1068-77.
33. Tsujii M, Kawano S, Tsuji S, et al. Increased expression of c-met messenger RNA following acute gastric injury in rats. Biochem Biophys Res Commun 1994;200:536-41.
34. Matsumoto K, Okazaki H, Nakamura T. Up-regulation of hepatocyte growth factor gene expression by interleukin-1 in human skin fibroblasts. Biochem Biophys Res Commun 1992; 188:235-45.
35. Matsumoto K, Okazaki H, Nakamura T. Novel function of prostaglandins as inducer of gene expression of HGF and putative mediators of tissue regeneration. J Biochem 1995; 117:458-64.
36. Takahashi M, Ota S, Hata Y, et al. Hepatocyte growth factor as a key to modulate anti-ulcer action of prostaglandins in stomach. J Clin Invest 1996;98:2588-96.
37. Yoshikawa T, Nakamura S, Takahashi S, Naito Y, Kondo M. Effect of sofalcone on gastric mucosal injury induced by ischemia-reperfusion and its antioxidant properties. J Clin Gastroenterol 1993;17(suppl 1):S111-5.
38. Miyata K, Kamato A, Nishida A, Takizawa K, Takeda M. Gastric mucosal protection by YM638, a novel leukotriene D4 receptor antagonist, in rats. Eur J Pharmacol 1995;276:165-75.
39. Kobayashi K, Higuchi K, Arakawa T, Matsumoto T, Nagura H. Effect of sofalcone on localization of 15-hydroxyprostaglandin dehydrogenase, an enzyme that metabolizes prostaglandin E2, in rat gastric mucosa: an immunohistochemical study. J Clin Gastroenterol 1992;14(suppl 1):S39-42.
40. Ota S, Takahashi M, Yoshiura K, et al. Antiulcer drugs and gastric prostaglandin E2: an in vitro study. J Clin Gastroenterol 1993;17(suppl 1):S15-21.
41. Tabata M, Tomomasa T, Itoh K, Morikawa A. Effect of 10% ethanol and sofalcone on prostaglandin E2 content, mucus gel thickness, and experimental ulcers in the stomach of developing rats. Digestion 1996;57:47-53.