Can epitope-focused vaccines select advantageous immune responses?

Molecular Medicine Today

Volumn 3, Issue 2, 1997, Pages 55-60

  Delves, P J ^a   Lund, T ^a   Roitt, I M ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN ANTIBODY;

ANTIBODY RESPONSE; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; DRUG POTENCY; HUMAN; IMMUNOCONTRACEPTION; IMMUNOGENICITY; IMMUNOSTIMULATION; MEMORY CELL; REVIEW; VACCINE PRODUCTION;

EID: 0031404534     PISSN: 13574310     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-4310(96)20036-X     Document Type: Article

References (14)

1. Nicholson B. Synthetic Vaccines 1994 Blackwell Science
2. Ahmed R. Gray D. Immunological memory and protective immunity: under-standing their relation Science 272 1996 54 60
3. Abbas A.K. Murphy K.M. Shur A. Functional diversity of helper T lymphocytes Nature 383 1996 787 793
4. Roitt I.M. Basic concepts and new aspects of vaccine development Parasitology 98 1989 S7 S12
5. Coffin J.M. Genetic variation in AIDS viruses Cell 46 1986 1 4
6. Deng H.K Site-directed mutagen-esis of HEL (hen egg lyso-zyme) and alter-ation in immunodominance patterns J. Cell. Biochem. Suppl. 18D 1994 289
7. Nardin E.H. Oliveira G.A. Calvo-Calle J.M. Nussenzweig R.S. The use of multiple antigen peptides in the analysis and induction of protective immune responses against infectious diseases Adv. Immunol. 60 1995 105 149
8. Thanavala Y. Novel approaches to vaccine development against HBV J. Biotechnol. 44 1996 67 73
9. Whittum-Hudson J.A Oral immunization with an anti-idiotypic anti-body to the exoglycolipid antigen protects against experimental Chlamydia trachomatis infection Nat. Med. 2 1996 1116 1121
10. Talwar G.P A vaccine that prevents pregnancy in women Proc. Natl. Acad. Sci. U.S. A. 91 1994 8532 8536
11. Lapthorn A.J. Crystal structure of human chorionic gonadotropin Nature 369 1994 455 461
12. Jackson A.M. Identification and selective destruction of shared epitopes in human chorionic-gonadotropin β-subunit J. Reprod. Immunol. 31 1996 21 36
13. Liu M.A. Hilleman M.R. Kurth R. DNA Vaccines: a New Era in Vaccinology Ann. New York Acad. Sci. Vol. 772 1995 Academy of Sciences New York
14. Metzler B. Wraith D.C. Mucosal tolerance in a murine model of experimental autoimmune encephalomyelitis Ann. New York Acad. Sci. 778 1996 228 242