Granulocyte-macrophage colony-stimulating factor and IL-5 activate mitogen-activated protein kinase through Jak2 kinase and phosphatidylinositol 3-kinase in human eosinophils

Journal of Allergy and Clinical Immunology

Volumn 100, Issue 6 II, 1997, Pages

  Hiraguri, M ^a   Miike, S ^a   Sano, H ^a   Kurasawa, K ^a   Saito, Y ^a   Iwamoto, I ^a  

^a CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Eosinophils; Granulocyte macrophage colony stimulating factor; IL 5; Jak2 kinase; Mitogen activated protein kinase; Phosphatidylinositol 3 kinase

Indexed keywords

ENZYME INHIBITOR; GENISTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 5; MITOGEN ACTIVATED PROTEIN KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; RAS PROTEIN; STAUROSPORINE; UNCLASSIFIED DRUG; WORTMANNIN;

ALLERGIC DISEASE; ARTICLE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EOSINOPHIL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INFLAMMATION; PRIORITY JOURNAL;

EID: 0031398848     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0091-6749(97)70004-6     Document Type: Article

References (58)

1. Y Sonoda Y Yang GG Wong SC Clark M Ogawa Analysis in serum-free culture of the targets of recombinant human hemopoietic growth factors: interleukin 3 and granulocyte/macrophage-colony-stimulating factor are specific for early developmental stages Proc Natl Acad Sci USA 85 1988 4360 4364
2. EJ Clutterbuck EMA Hirst CJ Sanderson Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures:comparison and interaction with IL-1, IL-3, IL-6, and GM-CSF Blood 73 1989 1504 1512
3. RAJ Warringa L Koenderman PTM Kok J Kreukniet PLB Bruijnzeel Modulation and induction of eosinophil chemotaxis by granulocyte-macrophage colony-stimulating factor and interleukin-3 Blood 77 1991 2694 2700
4. R Sehmi AJ Wardlaw O Cromwell K Kurihara P Waltmann AB Kay Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects Blood 79 1992 2952 2959
5. ME Rothenberg J Petersen RL Steves IL-5-dependent conversion of normodense human eosinophils to hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity, and sustained antibody-dependent cytotoxity J Immunol 143 1989 2311 2316
6. M Stern L Meagher J Savill C Haslett Apoptosis in human eosinophils: programmed cell death in the eosinophil leads to phagocytosis by macrophages and is modulated by IL-5 J Immunol 148 1992 3543 3549
7. AF Lopez MJ Elliott J Woodcock MA Vadas GM-CSF, IL-3 and IL-5: cross-competition on human haemopoietic cells Immunol Today 13 1992 495 500
8. K Pazdrak D Schreiber P Forsythe L Justement R Alam The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf -1-MEK-microtubule-associated protein kinase pathway J Exp Med 181 1995 1827 1834
9. K Pazdrak S Stafford R Alam The activation of the Jak -STAT 1 signaling pathway by IL-5 in eosinophils J Immunol 155 1995 397 402
10. ME Bates PJ Bertics WW Busse IL-5 activates a 45-kilodalton mitogen-activated protein (MAP) kinase and Jak -2 tyrosine kinase in human eosinophils J Immunol 156 1996 711 718
11. T Taniguchi Cytokine signaling through nonreceptor protein tyrosine kinases Science 268 1995 251 255
12. JE Darnell IM Kerr GR Stark Jak -STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins Science 264 1994 1415 1421
13. RJ Davis The mitogen-activated protein kinase signal transduction pathway J Biol Chem 268 1993 14553 14556
14. E Nishida Y Gotoh The MAP kinase cascade is essential for diverse signal transduction pathways Trends Biochem Sci 18 1993 128 131
15. cdc2 Biochim Biophys Acta 1135 1992 335 342
16. M Torres FL Hall K O'Neill Stimulation of human neutrophils with formyl-methionyl-leucyl-phenylalanine induces tyrosine phosphorylation and activation of two distinct mitogen-activated protein-kinases J Immunol 150 1993 1563 1578
17. TT Hansel IJM De Vries T Iff An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils J Immunol Methods 145 1991 105 110
18. GS Campbell LJ Christian C Carter-Su Evidence for involvement of the growth hormone receptor-associated tyrosine kinase in actions of growth hormone J Biol Chem 268 1993 7427 7434
19. H Yano S Nakanishi K Kimura Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells J Biol Chem 268 1993 25846 25856
20. T Okada L Sakuma Y Fukui O Hazeki M Ui Blockade of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase J Biol Chem 269 1994 3563 3567
21. ++ dependent protein kinase Biochem Biophys Res Commun 135 1986 397 402
22. CM Seynaeve MG Kazanietz PM Blumberg EA Sausville PJ Worland Differential inhibition of protein kinase C isozymes by UCN-01, a staurosporine analogue Mol Pharmacol 45 1994 1207 1214
23. N Meydan T Grunberger H Dadi Inhibition of acute lymphoblastic leukemia by a Jak -2 inhibitor Nature 379 1996 645 648
24. Y Gotoh E Nishida T Yamashita M Hoshi M Kawakami H Sakai Microtubule-associated protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells Eur J Biochem 193 1990 661 669
25. Y Gotoh E Nishida S Matsuda In vitro effects on microtubule dynamics of purified Xenopus M phase-associated MAP kinase Nature 349 1991 251 254
26. Y Gotoh K Moriyama S Matsuda Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF EMBO J 10 1991 2661 2668
27. Y Nishizuka Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C Science 258 1992 607 614
28. LL Lin M Wartmann AY Lin JL Knopf A Seth RJ Davis c PLA 2 is phosphorylated and activated by MAP kinase Cell 72 1993 269 278
29. JM Kyriakis H App X Zhang Raf -1 activates MAP kinase-kinase Nature 358 1992 417 421
30. P Dent W Haser TAJ Haystead LA Vincent TM Roberts TW Sturgill Activation of mitogen-activated protein kinase kinase by v- Raf in NIH 3T3 cells and in vitro Science 257 1992 1404 1407
31. CM Crews A Alessandrini RL Erikson The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product Science 258 1992 478 480
32. FW Quelle N Sato BA Witthuhn JAK 2 associates with the βc chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region Mol Cell Biol 14 1994 4335 4341
33. Y Zhao F Wagner SJ Frank AS Kraft The amino-terminal portion of the JAK 2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor βc chain J Biol Chem 270 1995 13814 13818
34. S Sato T Katagiri S Takaki IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases J Exp Med 180 1994 2101 2111
35. T van der Bruggen E Caldenhoven D Kanters Interleukin-5 signaling in human eosinophils involves JAK 2 tyrosine kinase and STAT1α Blood 85 1995 1442 1448
36. S Watanabe T Itoh K Arai JAK 2 is essential for activation of c- fos and c- myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells J Biol Chem 271 1996 12681 12686
37. M Jucker RA Feldman Identification of a new adapter protein that may link the common β subunit of the receptor for granulocyte/macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 to phosphatidylinositol 3-kinase J Biol Chem 270 1995 27817 27822
38. NB Prevarskaya RN Skryma P Vacher N Daniel J Djiane B Dufy Role of tyrosine phosphorylation in potassium channel activation: functional association with prolactin receptor and JAK 2 tyrosine kinase J Biol Chem 270 1995 24292 24299
39. GB Carey JP Liberti Stimulation of receptor-associated kinase, tyrosine kinase, and MAP kinase is required for prolactin-mediated macromolecular biosynthesis and mitogenesis in Nb2 lymphoma Arch Biochem Biophys 316 1995 179 189
40. SK Gupta C Gallego GL Johnson LE Heasley MAP kinase is constitutively activated in gip 2 and src transformed rat 1a fibroblasts J Biol Chem 267 1992 7987 7990
41. S Corey A Eguinoa K Puyana-Theall Granulocyte macrophage-colony stimulating factor stimulates both association and activation of phosphoinositide 3OH-kinase and src -related tyrosine kinase(s) in human myeloid cells EMBO J 12 1993 2681 2690
42. MJ Welham U Dechert KB Leslie F Jirik JW Schrader Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb 2 and phosphatidylinositol 3'-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins J Biol Chem 269 1994 23764 23768
43. MR Gold V Duronio SP Saxena JW Schrader R Aebersold Multiple cytokines activate phosphatidylinositol-3 kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins J Biol Chem 269 1994 5403 5412
44. DR Kaplan M Whitman B Schaffhausen Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity Cell 50 1987 1021 1029
45. L Varticovski B Druker D Morrison L Cantley T Roberts The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase Nature 342 1989 699 702
46. JD Bjorge TO Chan M Antczak HJ Kung DJ Fujita Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation Proc Natl Acad Sci USA 87 1990 3816 3820
47. NB Ruderman R Kapeller MF White LC Cantley Activation of phosphatidylinositol 3-kinase by insulin Proc Natl Acad Sci USA 87 1990 1411 1415
48. M Whitman CP Downes M Keeler T Keller L Cantley Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate Nature 332 1988 644 646
49. src protein Mol Cell Biol 9 1989 1651 1658
50. SR Coughlin JA Escobedo LT Williams Role of phosphatidylinositol kinase in PDGF receptor signal transduction Science 243 1989 1191 1194
51. LC Cantley KR Auger C Carpenter Oncogenes and signal transduction Cell 64 1991 281 302
52. JA Escobedo DR Kaplan WM Kavanaugh CW Turck LT Williams A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine Mol Cell Biol 11 1991 1125 1132
53. Q Hu A Klippel AJ Muslin WJ Fantl LT Williams Ras -dependent induction of cellular responses by constitutive active phosphatidylinositol 3-kinase Science 268 1995 100 102
54. K Yamauchi K Holt JE Pessin Phosphatidylinositol 3-kinase functions upstream of Ras and Raf in mediating insulin stimulation of c -fos transcription J Biol Chem 268 1993 14597 14600
55. A Sjolander EG Lapetina Agonist-induced association of the p21 ras GTPase-activating protein with phosphatidylinositol 3-kinase Biochem Biophys Res Commun 189 1992 1503 1508
56. K Yanagisawa M Sato T Horiuchi H Hasegawa S Fujita Difference in response to colony-stimulating factors and involvement of protein kinase C signal transduction system in three subclones from the ME-1 cell line and two sublines Blood 84 1994 84 93
57. M Nishimura K Kaku Y Azuno K Okafuji Y Inoue T Kaneko Stimulation of phosphoinositol turnover and protein kinase C activation by granulocyte-macrophage colony-stimulating factor in HL-60 cells Blood 80 1992 1045 1051
58. W Kolch G Heidecker G Kochs Protein kinase Cα activates Raf -1 by direct phosphorylation Nature 364 1993 249 252