Mice lacking 5-lipoxygenase have increased cortical bone thickness

Advances in Experimental Medicine and Biology

Volumn 433, Issue , 1997, Pages 299-302

  Bonewald, Lynda F ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; LEUKOTRIENE B4;

ARTICLE; BONE REMODELING; CELL DIFFERENTIATION; CORTICAL BONE; ENZYME DEFICIENCY; GROWTH REGULATION; HUMAN; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; OSTEOSCLEROSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

EID: 0031391218     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4899-1810-9_63     Document Type: Article

References (8)

1. Oreffo ROC, Marshall GJ, Kirchen M, Garcia G, Gallwitz WE, Chavex J, Mundy GR, Bonewald LF. Characterization of a cell line derived from a human giant cell tumor that stimulates osteoclastic bone resorption. Clin Orthop Related Res 296:229-241, (1993).
2. Gallwitz WE, Mundy GR, Lee CH, Qiao M, Roodman GD, Raftery M, Gaskell SJ, Bonewald LF. 5-lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices. J Biol Chem 268:10097-10094, (1993).
3. Garcia C, Qiao M, Chen D, Kirchen M, Gallwitz W Mundy GR, Bonewald LF. Effects of synthetic peptido-leukotrienes on bone resorption in vitro. J Bone Miner Res, 11:521-529, (1996).
4. Meghji S, Sandy JR, Scutt AM, Harvey W, Harris M. Stimulation of bone resorption by lipoxygenase metabolites of arachidonic acid. Prostaglandins 36:139-147, (1988).
5. 4 stimulates osteoclastic bone resorption both in vitro and in vivo. J Bone Miner Res, 11:1619-1629, (1996).
6. Ren W, Kinniburgh AJ, Dziak R. Regulation of c-myc protooncogene expression in osteoblastic cells by arachidonic acid metabolites: relationship to proliferation. Calcif Tissue Int 50:372-377, (1992).
7. 4 increases intracellular calcium concentration and phosphoinositide metabolism in mouse osteoblasts via cyclic adenosine 3′, 5′monophosphate-independent pathways. Endocrin 129:582-590, (1991).
8. Ren W and Dziak R. Effect of leukotrienes on osteoblastic cell proliferation. Calcif Tissue Int 49:197-201, (1991).