Sequences of recently identified adipokinetic peptides: What do they tell us with respect to their hyperlipaemic activity in migratory locusts?

Invertebrate Neuroscience

Volumn 3, Issue 2-3, 1997, Pages 217-222

  Gäde, Gerd ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

AKH family; Hyperlipaemia; Locusta migratoria; Receptors; Structure activity studies

Indexed keywords

ADIPOKINETIC HORMONE; AMINO ACID; LIPID; OCTAPEPTIDE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; CONFERENCE PAPER; DOSE RESPONSE; HYDROPHILICITY; HYDROPHOBICITY; HYPERLIPIDEMIA; LIPID METABOLISM; LOCUST; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0031370682     PISSN: 13542516     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02480377     Document Type: Conference Paper

References (31)

1. Gäde, G. (1990) Structure-function studies on hypertrehalosaemic and adipokinetic hormones: activity of naturally occurring analogues and some N- and C- terminally modified analogues. Physiol. Entomol., 15, 299-316.
2. Gäde, G. (1992) Structure-activity relationships for the carbohydrate-mobilizing action of further bioanalogues of the adipokinetic hormone/red pigment-concentrating hormone family of peptides. J. Insect Physiol., 38, 259-266.
3. Gäde, G. (1993) Structure-activity relationships for the lipid-mobilizing action of further bioanalogues of the adipokinetic hormone/red pigment-concentrating hormone family of peptides. J. Insect Physiol., 39, 375-383.
4. Gäde, G. (1995) Isolation and identification of AKH/RPCH family peptides in blister beetles (Meloidae). Physiol. Entomol., 20, 45-51.
5. Gäde, G. (1996) The revolution in insect neuropeptides illustrated by the adipokinetic hormone/red pigment-concentrating hormone family of peptides. Z. Naturforsch., 51C, 607-617.
6. Gäde, G. (1997a) The explosion of structural information on insect neuropeptides. In: Progress in the Chemistry of Organic Natural Products, ed. W. Hertz, G. W. Kirby, R. E. Moore, W. Steglich, and C. Tamm, pp 1-128. New York: Wien, Springer.
7. Gäde, G. (1997b) Distinct sequences of AKH/RPCH family members in beetle (Scarabaeus-species) corpus cardiacum contain three aromatic amino acid residues. Biochem. Biophys. Res., Commun., 230, 16-21.
8. Gäde, G. (1997c) Hyperprolinaemia caused by novel members of the adipokinetic hormone/red pigment-concentrating hormone family of peptides isolated from corpora cardiaca of onitine beetles. Biochem. J., 321, 201-206.
9. Gäde, G. and Hayes, T. K. (1995) Structure-activity relationships for Periplaneta americana hypertrehalosaemic hormone I: the importance of side chains and termini. Peptides, 16, 1173-1180.
10. Gäde, G. and M. P. Janssens (1994): Cicadas contain novel members of the AKH/RPCH family peptides with hypertrehalosaemic activity. Biol. Chem. Hoppe Seyler, 375, 803-809.
11. Gäde, G., Janssens, M. P.-E. and R. Kellner (1994) A novel peptide in the AKH/RPCH family isolated from the corpora cardiaca of the Emperor dragonfly, Anax imperator. Peptides, 15, 1-6.
12. Gäde, G. and Kellner, R. (1995) Isolation and structure of a novel adipokinetic peptide from the pyrgomorphid grasshopper. Phymateus leprosus. Regul. Peptides, 57, 247-252.
13. Gäde, G., Kellner, R. and Rinehart, K. L. (1996) Pyrgomorphid grasshoppers of the genus Phymateus contain species-specific decapeptides of the AKH/RPCH family regulating lipid-mobilization during flight. Physiol. Entomol., 21,193-202.
14. Goldsworthy, G.J., Lee, M. J. and Luswata, R. (1995) Adipokinetic hormones: Interassay variations in potencies as clues to hormone-receptor interactions in locust. In: Insects chemical, physiological and environmental aspects, ed. D. Konopinska, pp 17-27. Wroclaw: Wroclaw University Press.
15. Goldsworthy, G. J., Mallison, K. and Wheeler, C. H. (1986a) The relative potencies of two known locust adipokinetic hormones. J. Insect Physiol., 32, 95-101.
16. Goldsworthy, G. J., Mallison, K. Wheeler, C. H. and Gäde, G. (1986b) Relative adipokinetic activities of members of the adipokinetic hormone/red pigment concentrating hormone family. J. Insect Physiol., 32, 433-438.
17. Janssens, M.P.-E., Kellner, R. and Gäde, G. (1994) A novel adipokinetic octapeptide found in the damselflies Pseudagrion inconspicuum and Ischnura senegalensis. Biochem. J., 302, 539-543.
18. Lee, M. J. and Goldsworthy, G. J. (1995a): Acetate uptake test; the basis of a rapid method for determining potencies of adipokinetic peptides for structure-activity studies. J. Insect Physiol., 41, 163-170.
19. Lee, M. J. and Goldsworthy, G. J. (1995b) The preparation and use of dispersed cells from fat body of Locusta migratoria in a filtration plate assay for adipokinetic peptides. Anal. Biochem., 228, 155-161.
20. Lee, M. J. and Goldsworthy, G. J. (1996) Modified adipokinetic peptides containing two tryptophan residues and their activities in vitro and in vivo in Locusta. J. Comp. Physiol. B., 166, 61-67.
21. Lee, M. J., Goldsworthy, G. J., Poulos, C. P. and Velentza, A. (1996) Synthesis and biological activity of adipokinetic hormone analogues modified at the C-terminus. Peptides, 17, 1285-1290.
22. Liebrich, W., Kellner, R. and Gäde, G. (1995): Isolation and primary structures of neuropeptides of the AKH/RPCH family from various termite species. Peptides, 16, 559-564.
23. Oudejans, R. C. H. M., Vroemen, S. F., Jansen, R. F. R. and Van Der Horst, D. J. (1996) Locust adipokinetic hormones: Carrier-independent transport and differential inactivation at physiological concentrations during rest and flight. Proc. Natl. Acad. Sci. USA, 93, 8654-8659.
24. Poulos, C., Karagiannis, K., Lee, M. and Goldsworthy, G. (1994) Synthesis and biological activity of locust AKH-I and its analogues with modifications at the threonine residues. Int. J. Peptide Protein Res., 44, 589-593.
25. Raina, A. K. and Gäde, G. (1988) Insect peptide nomenclature. Insect Biochem., 18, 785-787.
26. Raina, A., Pannell, L., Konsky, J. and Jaffe, H. (1995) Primary structure of a novel neuropeptide isolated from the corpora cardiaca of periodical cicadas having adipokinetic and hypertrehalosemic activities. Insect Biochem. Mol. Biol., 25, 929-932.
27. Stone, J. V., Mordue, W., Broomfield, C. E. and Hardy, P. M. (1978) Structure-activity relationships for the lipid-mobilising action of locust adipokinetic hormone. Synthesis and activity of a series of hormone analogues. Eur. J. Biochem., 89, 195-202.
28. Veenstra, J. A. and Hagedorn, H. H. (1995) Isolation of two AKH-related peptides from cicadas. Arch. Insect Biochem. Physiol., 29, 391-396.
29. Wheeler, C. H., Drake, A. F., Wilmot, C. M., Thornton, J. M., Gäde, G. and Goldsworthy, G. J. (1990) Structures in the AKH family of neuropeptides. In: Insect Neurochemistry and Neurophysiology 1989, ed. A. B. Borkovec and E. P. Masler, pp 235-238. Clifton: The Humana Press Inc.
30. Ziegler, R., Jasensky, R. D. and Morimoto, H. (1995) Characterization of the adipokinetic hormone receptor from the fat body of Manduca sexta. Regul. Peptides, 57, 329-338, 1995.
31. 1H NMR spectroscopy and molecular mechanics. Biochem. Biophys. Res. Comm., 198, 228-235.