Diode laser based time-resolved detection and identification of individual mononucleotide molecules in aqueous solution

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 2985, Issue , 1997, Pages 61-68

  Sauer, Markus ^a   Zander, Christoph ^a   Müller, Ralph ^a   Göbel, Florian ^a   Schulz, Andreas ^a   Siebert, Stefan ^a   Drexhage, Karl H ^a   Wolfrum, Jürgen ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Pulsed diode lasers; Single molecule detection in solution; Time resolved fluorescence spectroscopy

Indexed keywords

CORRELATION METHODS; DYES; FLUORESCENCE; LASER PULSES; MAXIMUM LIKELIHOOD ESTIMATION; MOLECULES; NUCLEIC ACIDS; PHOTODETECTORS; PHOTONS; SPECTROSCOPIC ANALYSIS;

TIME-RESOLVED FLUORESCENCE SPECTROSCOPY;

SEMICONDUCTOR LASERS;

EID: 0031370677     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.274338     Document Type: Conference Paper

References (27)

1. Detection of single molecules of phycoerythrin in hydrodynamically focussed flows by laser induced fluorescence
2. High-speed DNA sequencing: An approach based upon fluorescence detection of single molecules
3. Detection of single fluorescent molecules
4. Single-molecule detection of rhodamine 6G in ethanolic solutions using continous wave laser excitation
5. Ultrasensitive detection of single molecules by fluorescence correlation spectroscopy
6. Diffusion of single molecules through a gaussian laser beam
7. Detection and identification of single molecules in solution
8. Detection and lifetime measurement of single molecules in flowing sample streams by laser-induced fluorescence
9. Laser-induced fluorescence detection of a single molecule in a capillary
10. Submillisecond detection of single rhodamine molecules in water
11. Probing individual molecules with confocal fluorescence microscopy
12. Real-time detection of single molecules in solution by confocal fluorescence microscopy
13. Detection and characterization of single molecules in aqueous solution
14. Error analysis of simple algorithms for determining fluorescence lifetimes in ultradilute dye Solutions
15. Bias and precision in the estimation of exponential decay parameters from sparse data
16. Fluorescence pattern recognition for ultrasensitive molecule identification: Comparison of experimental data and theoretical approximations
17. Single-molecule detection: Applications to ultrasensitive biochemical analysis
18. Ultrasensitive hybridization analysis using fluorescence correlation spectroscopy
19. Sorting single molecules: Applications to diagnostics and evolutionary biotechnology
20. Reduction of luminescent background in ultrasensitive fluorescence detection by photobleaching
21. Photon burst detection of single near-infrared fluorescent molecules
22. Steady-state and picosecond laser fluorescence studies of nonradiative pathways in tricarbocyanine dyes: Implications to the design of near-infrared fluorochromes with high fluorescence efficiencies
23. New fluorescent labels for time-resolved detection of biomolecules
24. Sensitive fluorescence detection in capillary gel electrophoresis using laser diodes and multiplex dyes
25. Diode laser based detection of single molecules in solution
26. Time-resolved identification of single molecules in solution with a pulsed semiconductor diode laser