Characterization of 8-(N-methylisopropyl)amino-N 6-(5′-endohydroxy-endonorbornyl)-9-methyladenine (WRC-0571), a highly potent and selective, non-xanthine antagonist of A1 adenosine receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 276, Issue 2, 1996, Pages 490-499

  Martin, P L ^a   Wysocki Jr , R J ^a   Barrett, R J ^a   May, J M ^b   Linden, J ^c  

^a ADERIS Pharmaceuticals Inc   (United States)

^b Alanex ^*  (United States)

^c UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 N (5 HYDROXYNORBORNAN 2 YL) 8 (N ISOPROPYL N METHYLAMINO) 9 METHYLADENINE; 9 METHYL 6 N (2 NORBORNYL)ADENINE; ADENINE; ADENOSINE RECEPTOR; DRUG DERIVATIVE; NORBORNANE DERIVATIVE;

ANIMAL; ARTICLE; CATTLE; DRUG ANTAGONISM; DRUG EFFECT; GUINEA PIG; HEART RATE; HUMAN; IN VITRO STUDY; MALE; RAT; SPRAGUE DAWLEY RAT; STRUCTURE ACTIVITY RELATION;

ADENINE; ANIMALS; CATTLE; GUINEA PIGS; HEART RATE; HUMANS; MALE; NORBORNANES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030078102     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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