Mechanism of Suppression of Macrophage Nitric Oxide Release by IL-13: Influence of the Macrophage Population

Journal of Immunology

Volumn 159, Issue 9, 1997, Pages 4506-4513

  Bogdan, Christian ^a,c   Thüring, Heike ^a   Dlaska, Margit ^b   Röllinghoff, Martin ^a   Weiss, Günter ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 13; NITRIC OXIDE;

ANIMAL; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; INTERLEUKIN-13; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; NITRIC OXIDE;

EID: 0031278413     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Zurawski, G., and J. E. de Vries. 1994. Interleukin-13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunol. Today 15:19.
2. Brown, K. D., S. M. Zurawski, T. R. Mosmann, and G. Zurawski. 1989. A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes. J. Immunol. 142: 679.
3. + T cells: modulation by interleukin-4 and interleukin-12. Eur. J. Immunol. 26:571.
4. van der Pouw Kraan, T. C. T. M., L. C. M. Boeije, J. T. M. Troon, S. K. Rutschmann, J. Wijdenes, and L. A. Aarden. 1996. Human IL-13 production is negatively influenced by CD3 engagement. J. Immunol. 156:1818.
5. Burd, P. R., W. C. Thompson, E. E. Max, and F. C. Mills. 1995. Activated mast cells produce interleukin-13. J. Exp. Med. 181:1373.
6. Li, H., T. C. Sim, and R. Alam. 1996. IL-13 released and localized in human basophils. J. Immunol. 156:4833.
7. Fior, R., N. Vita, M. Raphael, A. Minty, M.-C. Maillot, M.-C. Crevon, D. Caput, P. Biberfeld, P. Ferrara, P. Galanaud, and D. Emilie. 1994. Interleukin-13 gene expression by malignant and EBV-transforrned human B lymphocytes. Eur. Cytokine Netw. 5:593.
8. Colotta, F., F. Re, M. Muzio, N. Polentarutti, A. Minty, D. Caput, P. Ferrara, and A. Mantovani. 1994. Interleukin-13 induces expression and release of interleukin-1 decoy receptor in human polymorphonuclear cells. J. Biol. Chem. 269: 12403.
9. Derocq, J.-M., M. Segui, C. Poinot-Chazel, A. Minty, D. Caput, P. Ferrara, and P. Casellas. 1994. Interleukin-13 stimulates interleukin-6 production by human keratinocytes. FEBS Lett. 343:32.
10. Sébire, G., J.-F. Delfraissy, J. Demotes-Mainard, A. Oteifeh, D. Emilie, and M. Tardieu. 1996. Interleukin-13 and interleukin-4 act as interleukin-6 inducers in human microglial cells. Cytokine 8:636.
11. Sozzani, P., C. Cambbon, N. Vita, M.-H. Séguélas, D. Caput, P. Ferrara, and B. Pipy. 1995. Interleukin-13 inhibits protein kinase C-triggered respiratory burst in human monocytes. J. Biol. Chem. 1995:5084.
12. Saura, M., R. Martinez-Dalmau, A. Minty, D. Pérez-Sala, and S. Lamas. 1996. Interleukin-13 inhibits inducible nitric oxide synthase expression in human mesangial cells. Biochem. J. 313:641.
13. Berkman, N., A. Robichaud, R. A. Robbins, G. Roesems, E. B. Haddad, P. J. Barnes, and K. F. Chung. 1996. Inhibition of inducible nitric oxide synthase expression by interleukin-4 and interleukin-13 in human lung epithelial cells. Immunology 89:363.
14. Luttmann, W., B. Knoechel, M. Foerster, H. Matthys, J. C. Virchow, and C. Kroegel. 1996. Activation of human eosinophils by IL-13: induction of CD69 surface antigen, its relationship to messenger RNA expression, and promotion of cellular viability. J. Immunol. 157:1678.
15. Kotowicz, K., R. E. Callard, K. Friedrich, D. J. Matthews, and N. Klein. 1996. Biological activity of IL-4 and IL-13 on human endothelial cells: functional evidence that both cytokines act through the same receptor. Int. Immunol. 1996: 1915.
16. Riemann, D., A. Kehlen, and J. Langner. 1995. Stimulation of the expression and the enzyme activity of aminopeptidase N/CD13 and dipeptidylpeptidase IV/ CD26 on human renal cell carcinoma cells and renal tubular epithelial cells by T cell-derived cytokines, such as IL-4 and IL-13. Clin. Exp. Immunol. 100:277.
17. Lind, M., B. Deleuran, H. Yssel, E. Fink-Eriksen, and K. Thestrup-Pedersen. 1995. IL-4 and IL-13, but not IL-10, are chemotactic factors for human osteoblasts. Cytokine 7:78.
18. Jinquan, T., B. Deleuran, B. Gesser, H. Maare, M. Leuran, C. G. Larsen, and K. Thestrup-Pedersen. 1995. Regulation of human T lymphocyte chemotaxis in vitro by T cell-derived cytokines IL-2, IFN-γ, IL-4, IL-10, and IL-13. J. Immunol. 154:3742.
19. Doherty, T. M., R. Kastelein, S. Menon, S. Andrade, and R. L. Coffman. 1993. Modulation of murine macrophage function by IL-13. J. Immunol. 151:7151.
20. Doyle, A. G., G. Herbein, L. J. Montaner, A. J. Minty, D. Caput, P. Ferrara, and S. Gordon. 1994. Interleukin 13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-γ. Eur. J. Immunol. 24: 1441.
21. Weiss, G., C. Bogdan, and M. W. Hentze. 1997. Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13. J. Immunol. 158:420.
22. Lebel-Binay, S., B. Laguerre, F. Quintin-Colonna, H. Conjeaud, M. Magazin, B. Miloux, F. Pecceu, D. Caput, P. Ferrara, and D. Fradelizi. 1995. Experimental gene therapy of cancer using tumor cells engineered to secrete interleukin-13. Eur. J. Immunol. 25:2340.
23. Takeda, K., M. Kamanaka, T. Tanaka, T. Kishimoto, and S. Akira. 1996. Impaired IL-13-mediated functions of macrophages in Stat6-deficient mice. J. Immunol. 157:3220.
24. Bogdan, C. 1997. Of microbes, macrophages and NO. Behring Inst. Res. Commun. 99:58.
25. MacMicking, J., Q.-w. Xie, and C. Nathan. 1997. Nitric oxide and macrophage function. Annu. Rev. Immunol. 15:323.
26. Nathan, C., and Q.-w. Xie. 1994. Nitic oxide synthases: roles, tolls and controls. Cell 78:927.
27. Vodovotz, Y., C. Bogdan, J. Paik, Q.-w. Xie, and C. Nathan. 1993. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor-β. J. Exp. Med. 178:605.
28. Sands, W., V. Bulut, A. Severn, D. Xu, and F. Y. Liew. 1994. Inhibition of nitric oxide synthesis by interleukin-4 may involve inhibiting the activation of protein kinase C epsilon. Eur. J. Immunol. 24:2345.
29. Al-Ramadi, B. K., J. I. Meissler, Jr., D. Huang, and T. K. Eisenstein. 1992. Immunosuppression induced by nitric oxide and its inhibition by interleukin-4. Eur. J. Immunol. 22:2249.
30. Bogdan, C., Y. Vodovotz, J. Paik, Q.-w. Xie, and C. Nathan. 1994. Mechanism of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages. J. Leukocyte Biol. 55:227.
31. Cunha, F. Q., S. Moncada, and F. Y. Liew. 1992. Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-γ in murine macrophages. Biochem. Biophys. Res. Commun. 182:1155.
32. Gazzinelli, R. T., I. P. Oswald, S. L. James, and A. Sher. 1992. IL-10 inhibits parasite killing and nitrogen oxide production by IFN-γ activated macrophages. J. Immunol. 148:1792.
33. Wang, M.-H., G. W. Cox, T. Yoshimura, L. A. Sheffler, A. Skeel, and E. J. Leonard. 1994. Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin-or cytokine-stimulated mouse macrophages. J. Biol. Chem. 269:14027.
34. Rojas, A., R. Delgado, L. Glaria, and M. Palacios. 1993. Monocyte chemotactic protein-1 inhibits the induction of nitric oxide synthase in J774 cells. Biochem. Biophys. Res. Commun. 196:274.
35. Betz-Corradin, S., D. Heumann, P. Gallay, J. Smith, J. Mauël, and M. P. Glauser. 1994. Bactericidal/permeability-increasing protein inhibits induction of macrophage nitric oxide production by lipopolysaccharide. J. Infect. Dis. 169:105.
36. Star, R. A., N. Rajora, J. Huang, R. C. Stock, A. Catania, and J. M. Lipton. 1995. Evidence of autocrine modulation of macrophage nitric oxide synthase by α-melanocyte-stimulating hormone. Proc. Natl. Acad. Sci. USA 92:8016.
37. Rollo, E. E., D. L. Laskin, and D. T. Denhardt. 1996. Osteopontin inhibits nitric oxide production and cytotoxicity by activated RAW264.7 macrophages. J. Leukocyte Biol. 60:397.
38. Marcinkiewicz, J., A. Grabowska, J. Bereta, and T. Stelmaszynska. 1995. Taurine chloramine, a product of activated neutrophils, inhibits in vitro the generation of nitric oxide and other inflammatory mediators. J. Leukocyte Biol. 58:667.
39. Park, E., G. Schuller-Levis, and M. R. Quinn. 1995. Taurine chloramine inhibits production of nitric oxide and TNF-α in activated RAW264.7 cells by mechanisms that involve transcriptional and translational events. J. Immunol. 154:4778.
40. Weiss, G., G. Werner-Felmayer, E. R. Werner, K. Grünewald, H. Wachter, and M. W. Hentze. 1994. Iron regulates nitric oxide synthase activity by controlling nuclear transcription. J. Exp. Med. 180:969.
41. G-monomethyl-arginine in vitro and in vivo. Eur. J. Pharmacol. 294:703.
42. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
43. Bogdan, C., J. Paik, Y. Vodovotz, and C. Nathan. 1992. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-β and interleukin-10. J. Biol. Chem. 267:23301.
44. Stuehr, D. J., and M. A. Marletta. 1987. Synthesis of nitrite and nitrate in murine macrophage cell-lines. Cancer Res. 47:5590.
45. Iyengar, R., D. J. Stuehr, and M. A. Marletta. 1987. Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst. Proc. Natl. Acad. Sci. USA 84:6369.
46. Köhler, I., P. Alliger, A. Minty, D. Caput, P. Ferrara, B. Höll-Neugebauer, G. Rank, and E. P. Rieber. 1994. Human interleukin-13 activates the interleukin-4-dependent transcription factor NF-IL4 sharing a DNA binding motif with an interferon-γ-induced nuclear binding factor. FEBS Lett. 345:187.
47. Izuhara, K., T. Heike, T. Otsuka, K. Yamaoka, M. Mayumi, T. Imamura, Y. Niho, and N. Harada. 1996. Signal transduction pathway of interleukin-4 and interleukin-13 in human B cells derived from X-linked severe combined immunodeficiency patients. J. Biol. Chem. 271:619.
48. Murata, T., P. D. Noguchi, and R. K. Puri. 1996. IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines. J. Immunol. 156:2972.
49. Ohmori, Y., M. F. Smith, and T. A. Hamilton. 1996. IL-4-induced expression of the IL-1 receptor antagonist gene is mediated by STAT6. J. Immunol. 157:2058.
50. Kamijo, R., H. Harada, T. Matsuyama, M. Bosland, J. Gerecitano, D. Shapiro, J. Le, S. I. Koh, T. Kimura, S. J. Green, T. W. Mak, T. Taniguchi, and J. Vilcek. 1994. Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science 263:1612.
51. Martin, E., C. Nathan, and Q.-w. Xie. 1994. Role of interferon regulatory factor-1 in induction of nitric oxide synthase. J. Exp. Med. 180:977.
52. Modolell, M., I. M. Corraliza, F. Link, G. Soler, and K. Eichmann. 1995. Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow-derived macrophages by Th1 and Th2 macrophages. Eur. J. Immunol. 25:1101.
53. Munder, M., K. Eichmann, and M. Modolell. 1996. NO-synthase/arginase dichotomy in murine macrophages corresponds to Th1/Th2 pattern in CD4-T-cells. Immunobiology 196:145.
54. Bogdan, C., and C. Nathan. 1993. Modulation of macrophage function by transforming growth factor-β, interleukin 4 and interleukin 10. Ann. NY. Acad. Sci. 685:713.
55. Vodovotz, V., N. S. Kwon, M. Pospischil, J. Manning, J. Paik, and C. Nathan. 1994. Inactivation of nitric oxide synthase following prolonged incubation of mouse macrophages with IFN-γ and bacterial lipopolysaccharide. J. Immunol. 152:4110.
56. Albina, J. E., S. Cui, R. B. Mateo, and J. S. Reichner. 1993. Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J. Immunol. 150:5080.