Toxoplasma gondii: Dithiol-induced Ca2+ flux causes egress of parasites from the parasitophorous vacuole

Experimental Parasitology

Volumn 87, Issue 2, 1997, Pages 88-97

  Stommel, Elijah W ^a   Ely, Kenneth H ^a   Schwartzman, Joseph D ^a   Kasper, Lloyd H ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIMYCIN; CALCIUM ION; DITHIOTHREITOL; HYDROLASE; NUCLEOSIDE TRIPHOSPHATE;

ARTICLE; CELL VACUOLE; CONTROLLED STUDY; FIBROBLAST; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; TOXOPLASMA GONDII;

TOXOPLASMA GONDII;

EID: 0031260381     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1006/expr.1997.4187     Document Type: Article

References (30)

1. Asai, T., O'Sullivan, W. J., and Tatibana, M. 1983. A potent nucleoside triphosphate hydrolase from the parasitic protozoan Toxoplasma gondii. Purification, some properties, and activation by thiol compounds. Journal of Biological Chemistry 258, 6816-6822.
2. Asai, T., Miura, S., Sibley, L. D., Okabayashi, H., and Takeuchi, T. 1995. Biochemical and molecular characterization of nucleoside triphosphate hydrolase isozymes from the parasitic protozoan Toxoplasma gondii. Journal of Biological Chemistry 270, 11391-11397.
3. Bellomo, G., Mirabelli, F., Richelmi, P., and Orrenius, S. 1983. Critical role of sulfhydryl group(s) in ATP-dependent Ca2+ sequestration by the plasma membrane fraction from rat liver. FEBS Letters 163, 136-139.
4. Bermudes, D., Peck, K. R., Afifi, M. A., Beckers, C. J., and Joiner, K. A. 1994. Tandemly repeated genes encode nucleoside triphosphate hydrolase isoforms secreted into the parasitophorous vacuole of Toxoplasma gondii. Journal of Biological Chemistry 269, 29252-29260.
5. Berridge, M. J. 1993. Inositol trisphosphate and calcium signaling. Nature 361, 315-325.
6. Berridge, M. J., and Dupont, G. 1994. Spatial and temporal signaling by calcium. Current Opinion in Cell Biology 6, 267-274.
7. Dobrowolski, J. M., and Sibley, L. D. 1996. Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite. Cell 84, 933-939.
8. Endo, T., Sethi, K. K., and Piekarski, G. 1982. Toxoplasma gondii: calcium ionophore A23187-mediated exit of trophozoites from infected murine macrophages. Experimental Parasitology 53, 179-188.
9. Frenkel, J. K. 1973. Toxoplasmosis: Parasite life cycle, pathology and immunology. In "The Coccidia."(D. M. Hammond and P. L. Long, Eds.), p. 351. Univ. Park Press, Baltimore, MD.
10. Grynkiewicz, G., Poenie, M., and Tsien, R. Y. 1985. A new generation of Ca2+ indicators with greatly improved fluorescence properties. Journal of Biological Chemistry 260, 3440-3450.
11. Halonen, S. K., Weidner, E., and Siebenaller, J. F. 1996. Evidence for heterotrimeric GTP-binding proteins in Toxoplasma gondii. Journal of Eukaryotic Microbiology 43, 187-193.
12. Joiner, K. A., Fuhrman, S. A., Miettinen, H. M., Kasper, L. H., and Mellman, I. 1990. Toxoplasma gondii: fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts. Science 249, 641-646.
13. Jones, T. C., and Hirsch, J. G. 1972. The interaction between Toxoplasma gondii and mammalian cells. II. The absence of lysosomal fusion with phagocytic vacuoles containing living parasites. Journal of Experimental Medicine 136, 1173-1194.
14. 2+ sequestration during oxidative stress and its prevention by glutathione. Journal of Biological Chemistry 258, 6390-6393.
15. 2+] with fluorescent indicators. Methods in Cell Biology 40, 155-181.
16. Mondragon, R., Meza, I., and Frixione, E. 1994. Divalent cation and ATP dependent motility of Toxoplasma gondii tachyzoites after mild treatment with trypsin. Journal of Eukaryotic Microbiology 41, 330-337.
17. (2+)-dependence of conoid extrusion in Toxoplasma gondii tachyzoites. Journal of Eukaryotic Microbiology 43, 120-127.
18. Moreno, S. N., and Zhong, L. 1996. Acidocalcisomes in Toxoplasma gondii tachyzoites. Biochemical Journal 313, 655-659.
19. Pingret, L., Millot, J., Shanronov, S., Bonnhomme, A., Manfait, M., and Pinon, J. 1996. Relationship between intracellular free calcium concentrations and the intracellular development of Toxoplasma gondi. Journal of Histochemistry and Cytochemistry 44, 1123-1129.
20. Pruijn, F. B., Sibeijn, J. P., and Bast, A. 1990. Changes in inositol-1,4,5-trisphosphate binding to hepatic plasma membranes caused by temperature, N-ethylmaleimide and menadione. Biochemical Pharmacology 40, 1947-1952.
21. Roos, D. S., Donald, G. K., Morrissette, N. S., and Moulton, L. C. 1994. Molecular tools for genetic dissection of the parasite Toxoplasma gondii. Methods in Cell Biology 45, 27-63.
22. Schwab, J. C., Beckers, C. J., Joiner, K. A., Schwartzman, J. D., and Saffer, L. D. 1994. The parasitophorous vacuole membrane surrounding intracellular Toxoplasma gondii functions as a molecular sieve. Proceedings of the National Academy of Sciences, Washington DC. 91, 509-513.
23. Schwartzman, J. D., and Pfefferkorn, E. R. 1982. Toxoplasma gondii: Purine synthesis and salvage in mutant host cells and parasites. Experimental Parasitology 53, 77-86.
24. Sibley, L. D., Krahenbuhl, J. L., Adams, G., Mike, W., and Weidner, E. 1986. Toxoplasma modifies macrophage phagosomes by secretion of a vesicular network rich in surface proteins. The Journal of Cell Biology 103, 867-874.
25. Sibley, L. D., Niesman, I. R., Asai, T., and Takeuchi, T. 1994. Toxoplasma gondii: Secretion of a potent nucleoside triphosphate hydrolase into the parasitophorous vacuole. Experimental Parasitology 79, 301-311.
26. Sibley, L. D., Niesman, I. R., Parmley, S. F., Cesbron-Delauw, M. F., and Swann, K. 1995. Regulated secretion of multi-lamellar vesicles leads to formation of a tubulovesicular network in host-cell vacuoles occupied by Toxoplasma gondii. Journal of Cell Science 108, 1669-1677.
27. ++ flux. Molecular Biollogy of the Cell 7(S), 3249.
28. Swann, K. 1991. Thimerosal causes calcium oscillations and sensitizes calcium-induced calcium release in unfertilized hamster eggs. FEBS Letters 278, 175-178.
29. Thastrup, O., Cullen, P. J., Drobak, B. K., Hanley, M. R., and Dawson, A. P. 1990. Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase. Proceedings of the National Academy of Sciences, Washington, D.C. 87, 2466-2470.
30. Zaidi, N. F., Lagenaur, C. F., Hilkert, R. J., Xiong, H., Abramson, J. J., and Salama, G. 1989. Disulfide linkage of biotin identifies a 106-kDa Ca2+ release channel in sarcoplasmic reticulum. Journal of Biological Chemistry 264, 21737-21747.