In vitro 2-d networks of neurons characterized by processing the signals recorded with a planar microtransducer array

IEEE Transactions on Biomedical Engineering

Volumn 44, Issue 10, 1997, Pages 964-977

  Bove, Marco ^a   Grattarola, Massimo ^a   Verreschi, Giovanni ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

In vitro networks of neurons; Neuronal network dynamics; Planar substrate misroelectrode arrays; Signal processing tools; Simulated neuronal networks; Synaptic connections

Indexed keywords

COMPUTER SIMULATION; COMPUTER SOFTWARE; ELECTROPHYSIOLOGY; MICROELECTRODES; NEURAL NETWORKS; NEUROPHYSIOLOGY; SIGNAL PROCESSING; TRANSDUCERS;

NEURONAL NETWORK DYNAMICS;

BIOMEDICAL ENGINEERING;

ARTICLE; ARTIFICIAL NEURAL NETWORK; COMPUTER SIMULATION; SIGNAL PROCESSING;

EID: 0031259950     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/10.634649     Document Type: Article

References (33)

1. G. W. Gross Simultaneous single unit recording in vitro with a photoetched laser deinsulated gold multimicroelectrode surface IEEE Trans. Biomed. Eng. vol. BME-26 pp. 273-279 1979.
2. G. W. Gross B. K. Rhoades D. L. Reust and F. U. Schwalm Stimulation of monolayer networks in culture through thin film indiumtin oxide recording electrodes J. Neurosci. Meth. vol. 50 pp. 131-143 1994.
3. Y. Jimbo and A. Kawana Electrical stimulation and recording from cultured neurons using a planar array Bioelectrochem. Bioeng. vol. 29 pp. 193-204 1992.
4. Y. Jimbo H. P. C. Robinson and A. Kawana Simultaneous measurement of intracellular calcium and electrical activity from patterned neural networks in culture IEEE Trans. Biomed. Eng. vol. 40 pp. 804-810 1993.
5. G. W. Gross B. K. Rhoades and R. Jordan Neuronal networks for biochemical sensing Sensors and Actuators vol. B6 pp. 1-8 1992.
6. D. H. Perkel G. L. Gerstein and G. P. Moore Neuronal spike trains and stochastic point processes. I. The single spike trains Biophys. J. vol. 7 pp. 391-418 1967.
7. D. H. Perkel G. L. Gerstein and G. P. Moore Neuronal spike trains and stochastic point processes. II. Simultaneous spike trains Biophys. J. vol. 7 pp. 419-440 1967.
8. M. Abeles and M. H. Goldstein Multispike train analysis Proc. IEEE vol. 65 pp. 762-773 1977.
9. W. J. Meissen and W. J. M. Epping Detection and estimation of neural connectivity based on cross-correlation analysis Biol. Cybern. vol. 57 403-414 1987.
10. A. F. Atiya Recognition of multiunit neural signals IEEE Trans. Biomed. Eng. vol. 39 pp. 723-729 1992.
11. S. N. Gozani and J. P. Miller Optimal discrimination and classification of neuronal action potential waveforms from multiunit multichannel recordings using software-based linear filters IEEE Trans. Biomed. Eng. vol. 41 pp. 358-372 1994.
12. T. Chang S. J. Schiff T. Sauer J.-P. Gossard and R. E. Burke Stochastic versus deterministic variability in simple neuronal circuits: I. Monosynaptic spinal cord reflexes Biophys. J. vol. 67 pp. 671-683 1994.
13. S. J. Schiff K. Jerger T. Chang T. Sauer and P. G. Aitken Stochastic versus deterministic variability in simple neuronal circuits - II: Hippocampal slice Biophys. J. vol. 67 pp. 684-691 1994.
14. R. E. Hoffman W. Shi and B. S. Bunney Nonlinear sequence-dependent structure of nigral dopamine neuron interspike interval firing patterns Biophys. J. vol. 69 pp. 128-137 1995.
15. W. G. Regehr J. Pine and D. B. Rutledge A long-term in vitro silicon-based microelectrode neuron connection IEEE Trans. Biomed. Eng. vol. 35 pp. 1023-1031 1988.
16. M. Bove M. Grattarola S. Martinoia and G. Verreschi Interfacing cultured neurons to planar substrate microelectrodes: characterization of the neuron-to-microelectrode junction Bioelectrochem. Bioeng. vol. 38 pp. 255-265 1995.
17. J. G. Nicholls R. R. Stewart S. D. Erulkar and N. R. Saunders Reflexes fictive respiration and cell division in the brain and spinal cord of the newborn opussum monodelphis domestica isolated and mantained in vitro J. Exp. Biol. vol. 152 pp. 1-15 1990.
18. ++ of NMDA responses in spinal cord neurons Nature vol. 309 pp. 261-263 1984.
19. L. Nowak P. Bregestovksi P. Asher A. Heret and A. Prochiantz Magnesium gates glutamate-activated channels in mouse central neuron Nature vol. 307 pp. 462-465 1984.
20. J. G. Nicholls A. R. Martin and B. G. Wallace From Neuron to Brain 3rd ed Sunderland MMA: Sinauser Associates 1992.
21. H. P. C. Robinson M. Kawahara Y. Jimbo K. Torimitsu Y. Kuroda and A. Kawana Periodic synchronized bursting and intracellular calcium transients elicited by low magnesium in cultured cortical neurons J. Neurophys. vol. 70 pp. 1606-1616 1993.
22. L. Hodgkin and A. F. Huxley A quantitative description of membrane current and its applications to conduction and excitation in nerve J. Physiol. vol. 117 pp. 500-544 1952.
23. I. R. Epstein and E. Marder Multiples modes of a conditional neural oscillator Biol. Cybern. vol. 63 pp. 25-34 1990.
24. M. A. Dichter and G. D. Fischbach The action potential of chick dorsal root ganglion neurons maintained in cell culture J. Physiol. vol. 267 pp. 281-298 1977.
25. M. Grattarola M. Bove G. Verreschi S. Martinoia and M. Tedesco The neuro-electronic interface: measurements and model predictions J. Material Sci.: Materials in Med. vol. 7 pp. 363-366 1996.
26. R. E. Plant and M. Kim Mathematical description of a bursting pacemaker neuron by a modification of the Hodgkin-Huxley equations Biophys. J. vol. 16 pp. 227-244 1976.
27. A. Destexhe Z. Mainen and T. J. Sejnowski An efficient method for computing synaptic conductances based on a kinetic model of receptor binding Neural Comput. vol. 6 pp. 14-18 1994.
28. M. Grattarola and S. Martinoia Modeling the neuron-microtransducer junction: from extracellular to patch recording IEEE Trans. Biomed. Eng. vol. 40 pp. 35-41 1993.
29. M. Bove G. Massobrio S. Martinoia and M. Grattarola Realistic simulations of neurons by means of an ad hoc modified version of SPICE Biol. Cybern. vol. 71 pp. 137-145 1994.
30. E. L. Lehmann Nonparametrics: Statistical methods based on ranks San Francisco Holden-Day 1975.
31. Y. A. Barde D. Edgar and H. Thoenen Sensory neurons in culture: Changing requirements for survival factors during embryonic development Proc. Nat. Acad. Sci. 1980 vol. 77 pp. 1199-1203.
32. S. Martinoia M. Bove G. Carlini C. Ciccarelli M. Grattarola C. Storment and G. T. A. Kovacs A general-purpose system for long-term recording from a microelectrode array coupled to excitable cells J. Neurosci. Methods vol. 48 pp. 115-121 1993.
33. E. Maeda H. P. C. Robinson and A. Kawana The mechanisms of generation and propagation of synchronized bursting in developing networks of cortical neurons J. Neurosci. vol. 15 pp. 6834-6845 1995.