메뉴 건너뛰기




Volumn 159, Issue 7, 1997, Pages 3156-3167

Induction of T Cell Clonal Anergy Results in Resistance, whereas CD28-Mediated Costimulation Primes for Susceptibility to Fas- and Bax-Mediated Programmed Cell Death

Author keywords

[No Author keywords available]

Indexed keywords

BAD PROTEIN, HUMAN; BAD PROTEIN, MOUSE; BAX PROTEIN, HUMAN; BAX PROTEIN, MOUSE; BCL2L1 PROTEIN, HUMAN; BCL2L1 PROTEIN, MOUSE; CARRIER PROTEIN; CD28 ANTIGEN; CYSTEINE PROTEINASE; DNA FRAGMENT; FAS ANTIGEN; FAS LIGAND; FASL PROTEIN, MOUSE; FASLG PROTEIN, HUMAN; INTERLEUKIN 1; INTERLEUKIN 1BETA CONVERTING ENZYME; LIGAND; MEMBRANE PROTEIN; MESSENGER RNA; ONCOPROTEIN; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X;

EID: 0031255053     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (57)

References (77)
  • 2
    • 0029961719 scopus 로고    scopus 로고
    • Die and let live: Eliminating dangerous lymphocytes
    • Abbas, A. 1996. Die and let live: eliminating dangerous lymphocytes. Cell 84:655.
    • (1996) Cell , vol.84 , pp. 655
    • Abbas, A.1
  • 4
    • 0027315279 scopus 로고
    • Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells
    • Wesselborg, S., O. Janssen, and D. Kabelitz. 1993. Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J. Immunol. 150:4338.
    • (1993) J. Immunol. , vol.150 , pp. 4338
    • Wesselborg, S.1    Janssen, O.2    Kabelitz, D.3
  • 5
    • 0027314703 scopus 로고
    • Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
    • Russell, J. H., B. Rush, C. Weaver, and R. Wang. 1993. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc. Natl. Acad. Sci. USA 90:4409.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4409
    • Russell, J.H.1    Rush, B.2    Weaver, C.3    Wang, R.4
  • 6
    • 0028485743 scopus 로고
    • The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • Singer, G. G., and A. K. Abbas. 1994. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1:365.
    • (1994) Immunity , vol.1 , pp. 365
    • Singer, G.G.1    Abbas, A.K.2
  • 12
    • 0027145632 scopus 로고
    • Molecular cloning and expression of Fas ligand, a novel member of the tumor necrosis factor family
    • Suda, T., T. Takahashi, P. Golstein, and S. Nagata. 1993. Molecular cloning and expression of Fas ligand, a novel member of the tumor necrosis factor family. Cell 75:1169.
    • (1993) Cell , vol.75 , pp. 1169
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 14
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga, R., C. I. Brannan, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314.
    • (1992) Nature , vol.356 , pp. 314
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 15
  • 18
    • 0028941699 scopus 로고
    • Defective expression of hemopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis
    • Su, X., T. Zhou, Z. Wang, P. Yang, R. S. Jope, and J. D. Mountz. 1995. Defective expression of hemopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis. Immunity 2:353.
    • (1995) Immunity , vol.2 , pp. 353
    • Su, X.1    Zhou, T.2    Wang, Z.3    Yang, P.4    Jope, R.S.5    Mountz, J.D.6
  • 19
    • 0029890579 scopus 로고    scopus 로고
    • Characterization of apoptosis-resistant antigen-specific T cells in vivo
    • Zhang, L., R. G. Miller, and J. Zhang. 1996. Characterization of apoptosis-resistant antigen-specific T cells in vivo. J. Exp. Med. 183:2065.
    • (1996) J. Exp. Med. , vol.183 , pp. 2065
    • Zhang, L.1    Miller, R.G.2    Zhang, J.3
  • 20
    • 0027166048 scopus 로고
    • bcl-2 heterodimerizes in vivo with a conserved homolog, bax that accelerates programmed cell death
    • Oltvai, Z. N., C. L. Milliman, and S. J. Korsmeyer. 1993. bcl-2 heterodimerizes in vivo with a conserved homolog, bax that accelerates programmed cell death. Cell 74:609.
    • (1993) Cell , vol.74 , pp. 609
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 22
    • 0028809209 scopus 로고
    • Bad, a heterodimeric partner for bcl-xL and bcl-2, displaces bax and promotes cell death
    • Yang, E., J. Zha, J. Jockel, L. Boise, C. B. Thompson, and S. J. Korsmeyer. 1995. Bad, a heterodimeric partner for bcl-xL and bcl-2, displaces bax and promotes cell death. Cell 80:285.
    • (1995) Cell , vol.80 , pp. 285
    • Yang, E.1    Zha, J.2    Jockel, J.3    Boise, L.4    Thompson, C.B.5    Korsmeyer, S.J.6
  • 23
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the bcl2 family and cell death
    • Yang, A., and S. J. Korsmeyer. 1996. Molecular thanatopsis: a discourse on the bcl2 family and cell death. Blood 88:386.
    • (1996) Blood , vol.88 , pp. 386
    • Yang, A.1    Korsmeyer, S.J.2
  • 27
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2 binding protein with anti-cell death activity
    • Takayama, S., T. Sato, S. Krajewski, K. Kockel, S. Irie, J. A. Millan, and J. C. Reed. 1995. Cloning and functional analysis of BAG-1: a novel Bcl-2 binding protein with anti-cell death activity. Cell 80:279.
    • (1995) Cell , vol.80 , pp. 279
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kockel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 28
    • 0025937489 scopus 로고
    • Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis
    • Askew, D. S., R. A. Ashmun, B. C. Simmons, and J. L. Cleveland. 1991. Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene 6:1915.
    • (1991) Oncogene , vol.6 , pp. 1915
    • Askew, D.S.1    Ashmun, R.A.2    Simmons, B.C.3    Cleveland, J.L.4
  • 31
    • 0026645859 scopus 로고
    • Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines
    • Colotta, F., N. Polentarutti, M. Sironi, and A. Mantovani. 1992. Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines. J. Biol. Chem. 267:18278.
    • (1992) J. Biol. Chem. , vol.267 , pp. 18278
    • Colotta, F.1    Polentarutti, N.2    Sironi, M.3    Mantovani, A.4
  • 34
    • 0027284230 scopus 로고
    • Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation
    • Gimmi, C. D., G. J. Freeman, J. G. Gribben, G. Gray, and L. M. Nadler. 1993. Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc. Natl. Acad. Sci. USA 90:6586.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6586
    • Gimmi, C.D.1    Freeman, G.J.2    Gribben, J.G.3    Gray, G.4    Nadler, L.M.5
  • 35
    • 0029073050 scopus 로고
    • B7-1 and B7-2 do not deliver identical costimulatory signals since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4
    • Freeman, G. J., V. A. Boussiotis, A. Anumanthan, G. M. Bernstein, X.-Y. Ke, P. D. Rennert, G. S. Gray, J. G. Gribben, and L. M. Nadler. 1995. B7-1 and B7-2 do not deliver identical costimulatory signals since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. Immunity 2:523.
    • (1995) Immunity , vol.2 , pp. 523
    • Freeman, G.J.1    Boussiotis, V.A.2    Anumanthan, A.3    Bernstein, G.M.4    Ke, X.-Y.5    Rennert, P.D.6    Gray, G.S.7    Gribben, J.G.8    Nadler, L.M.9
  • 37
    • 0029810388 scopus 로고    scopus 로고
    • Differential association of protein tyrosine kinases with T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation
    • Boussiotis, V. A., D. L. Barber, B. J. Lee, G. J. Freeman, J. G. Gribben, and L. M. Nadler. 1996. Differential association of protein tyrosine kinases with T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation. J. Exp. Med. 184:365.
    • (1996) J. Exp. Med. , vol.184 , pp. 365
    • Boussiotis, V.A.1    Barber, D.L.2    Lee, B.J.3    Freeman, G.J.4    Gribben, J.G.5    Nadler, L.M.6
  • 39
    • 0029126581 scopus 로고
    • Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis
    • Tian, Q., J. L. Taupin, S. Elledge, M. Robertson, and P. Anderson. 1995. Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis. J. Exp. Med. 182:865.
    • (1995) J. Exp. Med. , vol.182 , pp. 865
    • Tian, Q.1    Taupin, J.L.2    Elledge, S.3    Robertson, M.4    Anderson, P.5
  • 40
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156.
    • (1987) Anal. Biochem. , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 43
    • 0028790829 scopus 로고
    • Bcl-2 blocks glucocorticoid- but not Fas or activation-induced apoptosis in a T cell hybridoma
    • Memon, S. A., M. B. Moreno, D. Petrak, and C. M. Zacharchuk. 1995. Bcl-2 blocks glucocorticoid- but not Fas or activation-induced apoptosis in a T cell hybridoma. J. Immunol. 155:4644.
    • (1995) J. Immunol. , vol.155 , pp. 4644
    • Memon, S.A.1    Moreno, M.B.2    Petrak, D.3    Zacharchuk, C.M.4
  • 44
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser, A., A. W. Harris, D. C. S. Huang, P. H. Krammer, and S. Cory. 1995. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J. 14:6136.
    • (1995) EMBO J. , vol.14 , pp. 6136
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.S.3    Krammer, P.H.4    Cory, S.5
  • 45
    • 0027182225 scopus 로고
    • Proptiocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle
    • Boehme, S. A., and M. J. Lenardo. 1993. Proptiocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur. J. Immunol. 23:1552.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1552
    • Boehme, S.A.1    Lenardo, M.J.2
  • 46
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse αβ T lymphocytes for apoptosis
    • Lenardo, M. J. 1991. Interleukin-2 programs mouse αβ T lymphocytes for apoptosis. Nature 353:858.
    • (1991) Nature , vol.353 , pp. 858
    • Lenardo, M.J.1
  • 47
    • 0027301903 scopus 로고
    • Altered protein tyrosine phosphorylation in anergic Th1 cells
    • Cho, E. A., M. P. Riley, A. L. Sillman, and H. Quill. 1993. Altered protein tyrosine phosphorylation in anergic Th1 cells. J. Immunol. 151:20.
    • (1993) J. Immunol. , vol.151 , pp. 20
    • Cho, E.A.1    Riley, M.P.2    Sillman, A.L.3    Quill, H.4
  • 49
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
    • Yin, X. M., Z. N. Oltvai, and S. J. Korsmeyer. 1994. BH1 and BH2 domains of bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369:321.
    • (1994) Nature , vol.369 , pp. 321
    • Yin, X.M.1    Oltvai, Z.N.2    Korsmeyer, S.J.3
  • 52
    • 0029906828 scopus 로고    scopus 로고
    • BAX-induced cell death may not require interleukin 1β-converting enzyme-like proteases
    • Xiang, J., D. T. Chao, and S. J. Korsmeyer. 1996. BAX-induced cell death may not require interleukin 1β-converting enzyme-like proteases. Proc. Natl. Acad. Sci. USA 93:14559.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14559
    • Xiang, J.1    Chao, D.T.2    Korsmeyer, S.J.3
  • 53
    • 0028087585 scopus 로고
    • Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis
    • Eischen, C. M., C. J. Dick, and P. J. Leibson. 1994. Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis. J. Immunol. 153: 1947.
    • (1994) J. Immunol. , vol.153 , pp. 1947
    • Eischen, C.M.1    Dick, C.J.2    Leibson, P.J.3
  • 55
    • 0027958565 scopus 로고
    • Anergic T-lymphocyte clones have altered inositol phosphate, calcium and tyrosine kinase signaling pathways
    • Gajewski, T. F., D. Qian, P. Fields, and F. W. Fitch. 1994. Anergic T-lymphocyte clones have altered inositol phosphate, calcium and tyrosine kinase signaling pathways. Proc. Natl. Acad. Sci. USA 91:38.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 38
    • Gajewski, T.F.1    Qian, D.2    Fields, P.3    Fitch, F.W.4
  • 58
    • 1842291572 scopus 로고    scopus 로고
    • Crucial role of Jak3 in negative selection of self-reactive T cells
    • Saijo, K., S. Y. Park, Y. Ishida, H. Arase, and T. Saito. 1997. Crucial role of Jak3 in negative selection of self-reactive T cells. J. Exp. Med. 185:351.
    • (1997) J. Exp. Med. , vol.185 , pp. 351
    • Saijo, K.1    Park, S.Y.2    Ishida, Y.3    Arase, H.4    Saito, T.5
  • 59
    • 0023225857 scopus 로고
    • Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation
    • Reed, J. C., Y. Tsujimoto, J. D. Alpers, C. M. Crose, and P. C. Nowell. 1987. Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation. Science 236:1295.
    • (1987) Science , vol.236 , pp. 1295
    • Reed, J.C.1    Tsujimoto, Y.2    Alpers, J.D.3    Crose, C.M.4    Nowell, P.C.5
  • 61
    • 0027451433 scopus 로고
    • B7 but not ICAM-1 costimulation prevents the induction of human alloantigen specific tolerance
    • Boussiotis, V. A., G. J. Freeman, G. Gray, J. Gribben, and L. M. Nadler. 1993. B7 but not ICAM-1 costimulation prevents the induction of human alloantigen specific tolerance. J. Exp. Med. 178:1753.
    • (1993) J. Exp. Med. , vol.178 , pp. 1753
    • Boussiotis, V.A.1    Freeman, G.J.2    Gray, G.3    Gribben, J.4    Nadler, L.M.5
  • 62
    • 0029953858 scopus 로고    scopus 로고
    • CTLA-4 ligation blocks CD28-dependent T cell activation
    • Walunas, T. L., C. Y. Bakker, and J. A. Bluestone. 1996. CTLA-4 ligation blocks CD28-dependent T cell activation. J. Exp. Med. 183:2541.
    • (1996) J. Exp. Med. , vol.183 , pp. 2541
    • Walunas, T.L.1    Bakker, C.Y.2    Bluestone, J.A.3
  • 63
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance
    • Van Parijs, L., A. Ibraghimov, and A. K. Abbas. 1996. The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 4:321.
    • (1996) Immunity , vol.4 , pp. 321
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 64
    • 0025204548 scopus 로고
    • Bcl-2 an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockendbery, D. M., G. Nunez, C. Milliman, R. D. Schreiber, and S. J. Korsmeyer. 1990. Bcl-2 an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334.
    • (1990) Nature , vol.348 , pp. 334
    • Hockendbery, D.M.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 65
    • 0028290446 scopus 로고
    • Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2
    • Gottschalk, A. R., L. H. Boise, C. B. Thompson, and J. Quintans. 1994. Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2. Proc. Natl. Acad. Sci. USA 91:7350.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7350
    • Gottschalk, A.R.1    Boise, L.H.2    Thompson, C.B.3    Quintans, J.4
  • 66
    • 0027161158 scopus 로고
    • Effect of bcl-2 on Fas antigen-mediated cell death
    • Itoh, N., Y. Tsujimoto, and S. Nagata. 1993. Effect of bcl-2 on Fas antigen-mediated cell death. J. Immunol. 151:621.
    • (1993) J. Immunol. , vol.151 , pp. 621
    • Itoh, N.1    Tsujimoto, Y.2    Nagata, S.3
  • 67
    • 0027057908 scopus 로고
    • CTLA-4 and CD28 mRNAs are coexpressed in most activated T cells after activation: Expression of CTLA-4 and CD28 messenger RNA does not correlate with the pattern of lymphokine production
    • Freeman, G. J., D. B. Lombard, C. D. Gimmi, S. A. Brod, K. Lee, J. C. Laning, D. A. Hafler, M. E. Dorf, G. Gray, H. Reiser, C. H. June, C. B. Thompson, and L. M. Nadler. 1992. CTLA-4 and CD28 mRNAs are coexpressed in most activated T cells after activation: expression of CTLA-4 and CD28 messenger RNA does not correlate with the pattern of lymphokine production. J. Immunol. 149:3795.
    • (1992) J. Immunol. , vol.149 , pp. 3795
    • Freeman, G.J.1    Lombard, D.B.2    Gimmi, C.D.3    Brod, S.A.4    Lee, K.5    Laning, J.C.6    Hafler, D.A.7    Dorf, M.E.8    Gray, G.9    Reiser, H.10    June, C.H.11    Thompson, C.B.12    Nadler, L.M.13
  • 70
    • 0029120245 scopus 로고
    • CD28 and CTLA4 have opposing effects on the response of T cells to stimulation
    • Krummel, M., and J. P. Allison. 1995. CD28 and CTLA4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182:459.
    • (1995) J. Exp. Med. , vol.182 , pp. 459
    • Krummel, M.1    Allison, J.P.2
  • 71
    • 0029899783 scopus 로고    scopus 로고
    • CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
    • Krummel, M. F., and J. P. Allison. 1996. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J. Exp. Med. 183:2533.
    • (1996) J. Exp. Med. , vol.183 , pp. 2533
    • Krummel, M.F.1    Allison, J.P.2
  • 73
    • 0028867420 scopus 로고
    • Loss of CTLA4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA4
    • Tivol, E. A., F. Borriello, N. A. Schweitzer, W. P. Lynch, J. A. Bluestone, and A. H. Sharpe. 1995. Loss of CTLA4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA4. Immunity 3:541.
    • (1995) Immunity , vol.3 , pp. 541
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, N.A.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 75
    • 0029035315 scopus 로고
    • Sphingomyelin-ceramide turnover in CD28 costimulatory signaling
    • Chan, G., and A. Ochi. 1995. Sphingomyelin-ceramide turnover in CD28 costimulatory signaling. Eur. J. Immunol. 25:1999.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1999
    • Chan, G.1    Ochi, A.2
  • 76
    • 0026560014 scopus 로고
    • Tumor necrosis factor-α activates the sphingomyelin signal transduction pathway in a cell-free system
    • Dressler, K. A., S. Mathias, and R. N. Kolesnick. 1992. Tumor necrosis factor-α activates the sphingomyelin signal transduction pathway in a cell-free system. Science 255:1715.
    • (1992) Science , vol.255 , pp. 1715
    • Dressler, K.A.1    Mathias, S.2    Kolesnick, R.N.3
  • 77
    • 0028670374 scopus 로고
    • Fas antigen and sphingomyelin-ceramide turnover-mediated signaling: Role in life and death of T lymphocytes
    • Gill, B. M., H. Nishikata, G. Chan, T. L. Delovitch, and A. Ochi. 1994. Fas antigen and sphingomyelin-ceramide turnover-mediated signaling: role in life and death of T lymphocytes. Immunol. Rev. 142:113.
    • (1994) Immunol. Rev. , vol.142 , pp. 113
    • Gill, B.M.1    Nishikata, H.2    Chan, G.3    Delovitch, T.L.4    Ochi, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.