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Volumn 30, Issue 10, 1997, Pages 1153-1156

A new brain metalloendopeptidase which degrades the Alzheimer ß-amyloid 1-40 peptide producing soluble fragments without neurotoxic effects

Author keywords

Alzheimer amyloid 1 40 peptide; Alzheimer's disease; Brain metalloendopeptidase

Indexed keywords

AMYLOID BETA PROTEIN; PROTEINASE;

EID: 0031242669     PISSN: 0100879X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0100-879X1997001000002     Document Type: Article
Times cited : (10)

References (13)
  • 1
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
    • Yankner BA, Duffy LK & Kirschner DA (1990). Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science, 250: 279-282.
    • (1990) Science , vol.250 , pp. 279-282
    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3
  • 2
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • Hardy JA & Higgins GA (1992). Alzheimer's disease: the amyloid cascade hypothesis. Science, 256: 184-185.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 7
    • 0028322017 scopus 로고
    • An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
    • Suzuki N, Cheung TT, Cai XD, Odaka A, Otvos Jr L, Eckman C, Golde TE & Younkin SG (1994). An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science, 264: 1336-1340.
    • (1994) Science , vol.264 , pp. 1336-1340
    • Suzuki, N.1    Cheung, T.T.2    Cai, X.D.3    Odaka, A.4    Otvos Jr., L.5    Eckman, C.6    Golde, T.E.7    Younkin, S.G.8
  • 8
    • 0028980783 scopus 로고
    • Intracellular production of beta A4 amyloid of Alzheimer's disease: Modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein
    • Fuller SJ, Storey E, Li QX, Smith AI, Beyreuther K & Masters CL (1995). Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein. Biochemistry, 34: 8091-8098.
    • (1995) Biochemistry , vol.34 , pp. 8091-8098
    • Fuller, S.J.1    Storey, E.2    Li, Q.X.3    Smith, A.I.4    Beyreuther, K.5    Masters, C.L.6
  • 10
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry, 72: 248-254.
    • (1976) Analytical Biochemistry , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 11
    • 0029905596 scopus 로고    scopus 로고
    • The carboxyl termini of beta-amyloid peptides 1-40 and 1-42 are generated by distinct gamma-secretase activities
    • Klafki HW, Abramowski RS, Paganetti PA & Staufenbiel M (1996). The carboxyl termini of beta-amyloid peptides 1-40 and 1-42 are generated by distinct gamma-secretase activities. Journal of Biological Chemistry, 271: 28655-28659.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 28655-28659
    • Klafki, H.W.1    Abramowski, R.S.2    Paganetti, P.A.3    Staufenbiel, M.4
  • 12
    • 0029803744 scopus 로고    scopus 로고
    • Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities
    • Citron M, Diehl TS, Gordon G, Biere AL, Seubert P & Selkoe DJ (1996). Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities. Proceedings of the National Academy of Sciences, USA, 93: 13170-13175.
    • (1996) Proceedings of the National Academy of Sciences, USA , vol.93 , pp. 13170-13175
    • Citron, M.1    Diehl, T.S.2    Gordon, G.3    Biere, A.L.4    Seubert, P.5    Selkoe, D.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.