Adeno-associated virus Rep78 inhibits oncogenic transformation of primary human keratinocytes by a human papillomavirus type 16-ras chimeric

Gynecologic Oncology

Volumn 66, Issue 3, 1997, Pages 487-494

  Hermonat, P L ^a   Plott, R T ^a,c   Santin, A D ^a,b   Parham, G P ^a   Flick, J T ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF BRESCIA   (Italy)

^c Dermik Laboratories Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

ARTICLE; CHIMERA; DISEASE ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; MALIGNANT TRANSFORMATION; PAPILLOMA VIRUS; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA; VIRUS TRANSFORMATION; VIRUS TYPING;

EID: 0031239899     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1997.4789     Document Type: Article

References (45)

1. 1. Durst M, Gissman H, Ikenberg H, zur Hausen H: A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions. Proc Natl Acad Sci USA 80:3812-3815, 1983
2. 2. Cullen AP, Reid R, Campion M, Lorincz AT: Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm. J Virol 65:606-612, 1991
3. 3. Blacklow NR, Hoggan MD, Rowe WP: Isolation of adeno-associated viruses from man. Proc Natl Acad Sci USA 58:1410-1415, 1967
4. 4. Bantel-Schaal U, zur Hausen H: Characterization of the DNA of a defective human parvovirus isolated from a genital site. Virology 134:52-63, 1984
5. 5. Tobiasch E, Rabreau M, Geletneky K, Larue-Charlus S, Severin F, Becker N, Schlehofer JR: Detection of adeno-associated virus DNA in human genital tissue and in material from spontaneous abortion. J Med Virol 44:215-222, 1995
6. 6. Han L, Parmley TH, Keith S, Kozlowski KJ, Smith LJ, Hermonat PL: High prevalence of adeno-associated virus (AAV) type 2 rep DNA in cervical materials: AAV may be sexually transmitted. Virus Genes 12: 47-52, 1996
7. 7. Mayor HD, Drake S, Stahmann J, Mumford DM: Antibodies to adeno-associated satellite virus and herpes simplex viruses in sera from cancer patients and normal adults. Am J Obstet Gynecol 126:100-105, 1976
8. 8. Georg-Fries B, Biederlack S, Wolf J, zur Hausen H: Analysis of proteins, helper dependence, and seroepidemiology of a human parvovirus. Virology 134:64-71, 1984
9. 9. Hermonat PL: The adeno-associated virus Rep78 gene inhibits cellular transformation induced by bovine papillomavirus. Virology 172:253-261, 1989
10. 10. Hermonat PL: Inhibition of bovine papillomavirus plasmid DNA replication by adeno-associated virus. Virology 189:329-333, 1992
11. 11. Hermonat PL: Adeno-associated virus inhibits human papillomavirus type 16: A viral interaction implicated in cervical cancer. Cancer Res 54:2278-2281, 1994
12. 12. Schmitt J, Schlehofer JR, Mergener K, Gissman L, zur Hausen H: Amplification of bovine papillomavirus DNA by N-methyl-N′-nitro-N-nitrosoguanidine, ultraviolet irradiation, or infection with herpes simplex virus. Virology 172:73-81, 1989
13. 13. Horer M, Weger S, Butz K, Hoppe-Seyler F, Geisen C, Kleinschmidt JA: Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters. J Virol 69:5485-5496, 1995
14. 14. Katz E, Carter BJ: Effect of adeno-associated virus on transformation of NIH 3T3 cells by ras gene gene and on tumorigenicity of an NIH 3T3 transformed cell line. Cancer Res 46:3023-3026, 1986
15. 15. Hermonat PL: Inhibition of H-ras expression by the adeno-associated virus Rep78 transformation suppressor gene product. Cancer Res 51:3373-3377, 1991
16. 16. Hermonat PL, Santin AD, Batchu RB: The adeno-associated virus Rp78 major regulatory/transformation suppressor binds Sp1 in vitro and evidence of a biological effect. Cancer Res 56:5299-5304, 1996
17. 17. Rittner K, Heilbronn R, Kleinschmidt JA, Sczakiel G: Adeno-associated virus type 2-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) replication: Involvement of p78rep/p68rep and the HIV long terminal repeat. J Gen Virol 73:2977-2981, 1992
18. 18. Antoni BA, Rabson AB, Miller IL, Trempe JP, Chejanovsky N, Carter BJ: Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells. J Virol 64:396-404, 1991
19. 19. Batchu RB, Hermonat PL: The tras-regulatory Rep78 protein of adeno-associated virus binds to the TAR region DNA of the human immunodeficiency virus type 1 long terminal repeat. FEBS Lett 367:267-271, 1995
20. 20. Mendleson E, Trempe JP, Carter BJ: Identification of the trans-active rep proteins of adeno-associated virus by antibodies to a synthetic oligopeptide. J Virol 60:823-832, 1986
21. 21. Hermonat PL, Labow MA, Wright R, Berns KI, Muzyczka N: Genetics of adeno-associated virus: Isolation and preliminary characterization of adeno-associated virus type 2 mutants. J Virol 51:329-333, 1984
22. 22. Tratschin J-D, Miller IL, Carter BJ: Genetic analysis of adeno-associated virus: Properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function. J Virol 51:611-619, 1984
23. 23. Labow MA, Hermonat PL, Berns KI: Positive and negative autoregulation of the adeno-associated virus type 2 genome. J Virol 60:251-258, 1986
24. 24. Tratschin J-D, Tal J, Carter BJ: Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral Rep gene product. Mol Cell Biol 5:3251-3260, 1986
25. 25. Im DS, Muzyczka N: The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity. Cell 61:447-457, 1990
26. 26. Ni TH, Zhou X, McCarty DM, Zolotukhin I, Muzyczka N: In vitro replication of adeno-associated virus DNA. J Virol 68:1128-1138, 1994
27. 27. Hermonat PL, Muzyczka N: Use of adeno-associated virus as a mammalian DNA cloning vector: Transduction of neomycin resistance into mammalian tissue culture cells. Proc Natl Acad Sci USA 81:6466-6470, 1984
28. 28. Romanczuk H, Thierry, Francoise T, Howley PM: Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. J Virol 64:2849-2859, 1990
29. 29. Southern EM: Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 98:503-518, 1975
30. 30. Hermonat PL, Spalholz BA, Howley PM: The bovine papillomavirus P2243 promoter is E2 franz-responsive: Evidence for E2 autoregulation. EMBO J 7:2815-2822, 1988
31. 31. Phelps WC, Yee CL, Munger K, Howley PM: The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to adenovirus E1a. Cell 53:539-548, 1988
32. 32. Crook T, Storey A, Almond N, Osborn K, Crawford L: Human papillomavirus type 16 cooperates with activated ras and fos oncogenes in hormone-dependent transformation of primary mouse cells. Proc Natl Acad Sci USA 85:8820-8824, 1985
33. 33. Schlegel R, Phelps WC, Zhang Y-L, Barbosa M: Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma. EMBO J 7:3181-3187, 1988
34. 34. Munger K, Phelps WC, Bubb V, Howley PM, Schlegel R: The E6 and E7 genes of the human papillomavirus together are necessary and sufficient for transformation of primary human keratinocytes. J Virol 63:4417-4421, 1989
35. 35. Hermonat PL: Down regulation of the human c-fos and c-myc proto-oncogene promoters by adeno-associated virus Rep78. Cancer Lett 81:129-136, 1994
36. 36. Klein-Bauernschmitt P, zur Hausen H, Schlehofer JR: Induction of differentiation-associated changes in established human cells by infection with adeno-associated virus. J Virol 66:4191-4200, 1992
37. 37. Dupressor T, Vanacker JM, Cornells JJ, Duponchel N, Rommelaere J: Inhibition by parvovirus H-1 of the formation of tumors in nude mice and colonies in vitro by transformed mammary epithelial cells. Cancer Res 49:3203-3208, 1989
38. 38. Salome N, van Hille B, Duponchel N, Meneguzzi G, Cuzin F, Rommelaere J, Cornelis JJ: Sensitization of transformed cells to parvovirus MVMp is restricted to specific oncogenes. Oncogene 5:123-130, 1990
39. 39. Caillet-Fauquet P, Perros M, Brandenburger A, Spegelaere P, Rommelaere J: Programmed killing of human cells by means of an inducible clone of parvoviral genes encoding non-structural proteins. EMBO J 9:2989-2995, 1990
40. 40. Yang Q, Fang C, Trempe JP: Characterization of cell lines which inducibly express the adeno-associated virus rep proteins. J Virol 68:4847-4856, 1994
41. 41. Holscher CA, Horer M, Kleinschmidt JA, Zentgraf H, Burkle A, Heilbronn R: Cell lines inducibly expressing the adeno-associated virus (AAV) rep gene: Requirements for productive replication of rep negative AAV mutants. J Virol 68:7169-7177, 1994
42. 42. Blackwood EM, Eisenman RN: Max: A helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with myc. Science 251:1211-1217, 1991
43. 43. Halazonetis TD, Georgopoulos K, Greenberg ME, Leder P: c-Jun dimerizes with itself and with c-fos, forming complexes with different DNA affinities. Cell 55:917-924, 1988
44. 44. Li R, Knight JD, Jackson SP, Botchan MR: Direct interaction between Sp1 and BPV enhancer E2 protein mediates synergistic activation of transcription. Cell 65:493-505, 1991
45. 45. Shapiro HM: Practical Flow Cytometry, New York, NY, A. R. Liss, 1988, pp 115-198