Investigation of the feasibility of directly-coupled HPLC-NMR with 2H detection with application to the metabolism of N-dimethylformamide-d7

Journal of Pharmaceutical and Biomedical Analysis

Volumn 16, Issue 1, 1997, Pages 1-5

  Farrant, R Duncan ^a   Cupid, Belinda C ^b   Nicholson, Jeremy K ^b   Lindon, John C ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

2H NMR; DMF; HPLC NMR; Metabolism; Urine

Indexed keywords

DRUG METABOLITE; N,N DIMETHYLFORMAMIDE;

ANIMAL EXPERIMENT; ARTICLE; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT; URINE;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEUTERIUM; DIMETHYLFORMAMIDE; FEASIBILITY STUDIES; MAGNETIC RESONANCE SPECTROSCOPY; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; URINE;

EID: 0031239146     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(96)01958-9     Document Type: Article

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