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Volumn 4, Issue 9, 1997, Pages 653-657

Quantitative electrospray mass spectrometry for the rapid assay of enzyme inhibitors

Author keywords

Electrospray mass spectrometry; Galactosyltransferase; Quantitative enzyme assay

Indexed keywords


EID: 0031238811     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(97)90220-9     Document Type: Article
Times cited : (59)

References (43)
  • 1
    • 0028100318 scopus 로고
    • Peptidosteroidal receptors for opioid peptides - Sequence-selective binding using a synthetic receptor library
    • Boyce, R., Li, G., Nestler, H.P., Suenaga, T. & Still, W.C. (1994). Peptidosteroidal receptors for opioid peptides - sequence-selective binding using a synthetic receptor library. J. Am. Chem. Soc. 116, 7955-7956.
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 7955-7956
    • Boyce, R.1    Li, G.2    Nestler, H.P.3    Suenaga, T.4    Still, W.C.5
  • 2
    • 0028243847 scopus 로고
    • Application of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries
    • Gallop, M.A, Barrett, R.W., Dower, W.J., Fodor, S.P.A. & Gordon, E.M. (1994). Application of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries. J. Med. Chem. 37, 1233-1251.
    • (1994) J. Med. Chem. , vol.37 , pp. 1233-1251
    • Gallop, M.A.1    Barrett, R.W.2    Dower, W.J.3    Fodor, S.P.A.4    Gordon, E.M.5
  • 3
    • 0028151071 scopus 로고
    • Library-based lead compound discovery - Antioxidants by an analogous synthesis deconvolutive assay strategy
    • Kurth, MJ., et al., & Green, C. (1994). Library-based lead compound discovery - antioxidants by an analogous synthesis deconvolutive assay strategy. J. Org. Chem. 59, 5862-5864.
    • (1994) J. Org. Chem. , vol.59 , pp. 5862-5864
    • Kurth, M.J.1    Green, C.2
  • 4
    • 33751157590 scopus 로고
    • A general method for molecular tagging of encoded combinatorial chemistry libraries
    • Nestler, H.P., Bartett, P.A. & Still, W.C. (1994). A general method for molecular tagging of encoded combinatorial chemistry libraries. J. Org. Chem. 59, 4723-4724.
    • (1994) J. Org. Chem. , vol.59 , pp. 4723-4724
    • Nestler, H.P.1    Bartett, P.A.2    Still, W.C.3
  • 6
    • 10244273514 scopus 로고
    • A general solid-phase synthesis strategy for the preparation of 2-pyrrolidinemethanol ligands
    • Liu, G. & Ellman, J.A. (1995). A general solid-phase synthesis strategy for the preparation of 2-pyrrolidinemethanol ligands. J. Org. Chem. 60, 7712-7713.
    • (1995) J. Org. Chem. , vol.60 , pp. 7712-7713
    • Liu, G.1    Ellman, J.A.2
  • 7
    • 0028939901 scopus 로고
    • A review of the utility of soluble peptide combinatorial libraries
    • Pinilla, C., et al., & Houghten, R.A. (1995). A review of the utility of soluble peptide combinatorial libraries. Biopolymers 37, 221-240.
    • (1995) Biopolymers , vol.37 , pp. 221-240
    • Pinilla, C.1    Houghten, R.A.2
  • 8
    • 0029811207 scopus 로고    scopus 로고
    • Combinatorial approach to the discovery of novel coordination complexes
    • Francis, M.B., Finney, N.S. & Jacobsen, E.N. (1996). Combinatorial approach to the discovery of novel coordination complexes. J. Am. Chem. Soc. 118, 8983-8984.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 8983-8984
    • Francis, M.B.1    Finney, N.S.2    Jacobsen, E.N.3
  • 9
    • 0029818299 scopus 로고    scopus 로고
    • Non nucleic acid inhibitors of protein-DNA interactions identified through combinatorial chemistry
    • Stevens, S.Y., Bunin, B.A., Plunkett, M.J., Swanson, P.C., Ellman, J.A. & Glick, G.D. (1996). Non nucleic acid inhibitors of protein-DNA interactions identified through combinatorial chemistry. J. Am. Chem. Soc. 118, 10650-10651.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 10650-10651
    • Stevens, S.Y.1    Bunin, B.A.2    Plunkett, M.J.3    Swanson, P.C.4    Ellman, J.A.5    Glick, G.D.6
  • 10
    • 7044263277 scopus 로고    scopus 로고
    • Synthesis and applications of small molecule libraries
    • Thompson, L.A. & Ellman, J.A. (1996). Synthesis and applications of small molecule libraries. Chem. Rev. 96, 555-600.
    • (1996) Chem. Rev. , vol.96 , pp. 555-600
    • Thompson, L.A.1    Ellman, J.A.2
  • 11
    • 10544229790 scopus 로고    scopus 로고
    • Parallel synthesis and screening of a solid phase carbohydrate library
    • Liang, R., et al., & Kahne, D. (1996). Parallel synthesis and screening of a solid phase carbohydrate library. Science 274, 1520-1522.
    • (1996) Science , vol.274 , pp. 1520-1522
    • Liang, R.1    Kahne, D.2
  • 12
    • 0031012062 scopus 로고    scopus 로고
    • Display of heterologous proteins on the surface of microorganisms: From the screening of combinatorial libraries to live recombinant vaccines
    • Georgiou, G., Stathopoulos, C., Daugherty, P.S., Nayak, A.R., Iverson, B.L. & Curtiss III, R. (1997). Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines. Nature Biotechnol. 15, 29-34.
    • (1997) Nature Biotechnol. , vol.15 , pp. 29-34
    • Georgiou, G.1    Stathopoulos, C.2    Daugherty, P.S.3    Nayak, A.R.4    Iverson, B.L.5    Curtiss III, R.6
  • 14
    • 0029841811 scopus 로고    scopus 로고
    • Affinity capillary electrophoresis mass spectrometry for screening combinatorial libraries
    • Chu, Y.H., Dunayevskiy, Y.M., Kirby, D.P., Vouros, P. & Karger, B.L. (1996). Affinity capillary electrophoresis mass spectrometry for screening combinatorial libraries. J. Am. Chem. Soc. 118, 7827-7835.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 7827-7835
    • Chu, Y.H.1    Dunayevskiy, Y.M.2    Kirby, D.P.3    Vouros, P.4    Karger, B.L.5
  • 15
    • 0029347588 scopus 로고
    • Using electrospray ionization FTICR mass spectrometry to study competitive binding of inhibitors to carbonic anhydrase
    • Cheng, X., et al., & Smith, R.D. (1995). Using electrospray ionization FTICR mass spectrometry to study competitive binding of inhibitors to carbonic anhydrase. J. Am. Chem. Soc. 117, 8859-8860.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 8859-8860
    • Cheng, X.1    Smith, R.D.2
  • 16
    • 0029109073 scopus 로고
    • Generation and screening of combinatorial peptide libraries designed for rapid sequencing by mass spectrometry
    • Youngquist, R.S., Fuentes, G.R., Lacey, M.P. & Keough, T. (1995). Generation and screening of combinatorial peptide libraries designed for rapid sequencing by mass spectrometry. J. Am. Chem. Soc. 117, 3900-3906.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 3900-3906
    • Youngquist, R.S.1    Fuentes, G.R.2    Lacey, M.P.3    Keough, T.4
  • 17
    • 0030056289 scopus 로고    scopus 로고
    • Combinatorial peptide libraries: Robotic synthesis and analysis by NMR, mass spectrometry, tandem mass spectrometry and high-performance capillary electrophoresis techniques
    • Boutin, J.A., et al., & Fauchere, J.L (1996). Combinatorial peptide libraries: robotic synthesis and analysis by NMR, mass spectrometry, tandem mass spectrometry and high-performance capillary electrophoresis techniques. Anal. Biochem. 234, 126-141.
    • (1996) Anal. Biochem. , vol.234 , pp. 126-141
    • Boutin, J.A.1    Fauchere, J.L.2
  • 18
    • 15844410706 scopus 로고    scopus 로고
    • Screening derivatized peptide libraries for tight binding inhibitors to carbonic anhydrase II by electrospray ionization-mass spectrometry
    • Gao, J., et al., & Whitesides, G.M. (1996). Screening derivatized peptide libraries for tight binding inhibitors to carbonic anhydrase II by electrospray ionization-mass spectrometry. J Med Chem. 39, 1949-1955.
    • (1996) J Med Chem. , vol.39 , pp. 1949-1955
    • Gao, J.1    Whitesides, G.M.2
  • 19
    • 0029074409 scopus 로고
    • Oxidative decarboxylation of peptides catalyzed by flavoprotein EpiD. Determination of substrate specificity using peptide libraries and neutral loss mass spectrometry
    • Kupke, T., Kempter, C., Jung, G. & Gostz, F. (1995). Oxidative decarboxylation of peptides catalyzed by flavoprotein EpiD. Determination of substrate specificity using peptide libraries and neutral loss mass spectrometry. J. Biol. Chem. 270, 11282-11289.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11282-11289
    • Kupke, T.1    Kempter, C.2    Jung, G.3    Gostz, F.4
  • 20
    • 0030988935 scopus 로고    scopus 로고
    • Spectrometrically monitored selection experiments: Quantitative laser desorption mass spectrometry of small chemical libraries
    • Berlin, K., Jain, R.K., Tetzlaff, C., Steinbeck, C. & Richert, C. (1997). Spectrometrically monitored selection experiments: quantitative laser desorption mass spectrometry of small chemical libraries. Chem. Biol. 4, 63-77.
    • (1997) Chem. Biol. , vol.4 , pp. 63-77
    • Berlin, K.1    Jain, R.K.2    Tetzlaff, C.3    Steinbeck, C.4    Richert, C.5
  • 21
    • 0030842654 scopus 로고    scopus 로고
    • An automated MALDI mass spectrometry approach for optimizing cyclosporin extraction and quantitation
    • in press
    • Wu, J., Chatman, K., Harris, K. & Siuzdak, G. (1997). An automated MALDI mass spectrometry approach for optimizing cyclosporin extraction and quantitation. Anal. Chem., in press.
    • (1997) Anal. Chem.
    • Wu, J.1    Chatman, K.2    Harris, K.3    Siuzdak, G.4
  • 22
    • 33845183392 scopus 로고
    • Real-time reaction monitoring by continuous-introduction ion-spray tandem mass spectrometry
    • Lee, E.D., Muck, W., Henion, J.D. & Covey, T.R. (1989). Real-time reaction monitoring by continuous-introduction ion-spray tandem mass spectrometry. J. Am. Chem. Soc. 111, 4600-4604.
    • (1989) J. Am. Chem. Soc. , vol.111 , pp. 4600-4604
    • Lee, E.D.1    Muck, W.2    Henion, J.D.3    Covey, T.R.4
  • 23
    • 0027994563 scopus 로고
    • Quantitative capillary electrophoresis ion spray mass spectrometry on a benchtop ion trap for the determination of isoquinoline alkaloids
    • Henion, J.D., Nlordehai, A.V. & Cai, J.Y. (1994). Quantitative capillary electrophoresis ion spray mass spectrometry on a benchtop ion trap for the determination of isoquinoline alkaloids. Anal. Chem. 66, 2103-2109.
    • (1994) Anal. Chem. , vol.66 , pp. 2103-2109
    • Henion, J.D.1    Nlordehai, A.V.2    Cai, J.Y.3
  • 24
    • 0030482416 scopus 로고    scopus 로고
    • High throughput electrospray mass spectrometry of combinatorial chemistry racks with automated contamination surveillance and results reporting
    • Hegy, G., Gorlach, E., Richmond, R. & Bitsch, F. (1996). High throughput electrospray mass spectrometry of combinatorial chemistry racks with automated contamination surveillance and results reporting. Rapid Commun. Mass Spectrom. 10, 1894-1900.
    • (1996) Rapid Commun. Mass Spectrom. , vol.10 , pp. 1894-1900
    • Hegy, G.1    Gorlach, E.2    Richmond, R.3    Bitsch, F.4
  • 26
    • 0027318961 scopus 로고
    • Biological roles of oligosaccharides - All theories are correct
    • Varki, A. (1993). Biological roles of oligosaccharides - all theories are correct. Glycobiology 3, 97-130.
    • (1993) Glycobiology , vol.3 , pp. 97-130
    • Varki, A.1
  • 27
    • 0023223825 scopus 로고
    • Synthesis of glycopyranosylphosphonate analogs of certain natural nucleoside diphosphate sugars as potential inhibitors of glycosyltransferases
    • Vaghefi, M.M., Bernacki, R.J., Dalley, K., Wilson, B.E. & Robins, R.K. (1987). Synthesis of glycopyranosylphosphonate analogs of certain natural nucleoside diphosphate sugars as potential inhibitors of glycosyltransferases. J. Med. Chem. 30, 1383-1391.
    • (1987) J. Med. Chem. , vol.30 , pp. 1383-1391
    • Vaghefi, M.M.1    Bernacki, R.J.2    Dalley, K.3    Wilson, B.E.4    Robins, R.K.5
  • 28
    • 0023223408 scopus 로고
    • Synthesis of certain nucleoside methylenediphosphonate sugars as potential inhibitors of glycosyltransferases
    • Vaghefi, M.M., Bernacki, R.J., Hennen, W.J. & Robins, R.K. (1987). Synthesis of certain nucleoside methylenediphosphonate sugars as potential inhibitors of glycosyltransferases. J. Med. Chem. 30, 1391-1399.
    • (1987) J. Med. Chem. , vol.30 , pp. 1391-1399
    • Vaghefi, M.M.1    Bernacki, R.J.2    Hennen, W.J.3    Robins, R.K.4
  • 29
    • 0024325251 scopus 로고
    • A bisubstrate analog inhibitor for α-(1,2)-fucosyltransferase
    • Palcic, M.M., Heerze, L.D., Srivastava, O.P. & Hindsgaul, O. (1989). A bisubstrate analog inhibitor for α-(1,2)-fucosyltransferase. J. Biol. Chem. 264, 17174-17181.
    • (1989) J. Biol. Chem. , vol.264 , pp. 17174-17181
    • Palcic, M.M.1    Heerze, L.D.2    Srivastava, O.P.3    Hindsgaul, O.4
  • 30
    • 0025991462 scopus 로고
    • Evaluation of deoxygenated oligosaccharide acceptor analogs as specific inhibitors of glycosyltransferases
    • Hindsgaul, O., et al., & Palcic, M.M. (1991). Evaluation of deoxygenated oligosaccharide acceptor analogs as specific inhibitors of glycosyltransferases. J. Biol. Chem. 266, 17858-17862.
    • (1991) J. Biol. Chem. , vol.266 , pp. 17858-17862
    • Hindsgaul, O.1    Palcic, M.M.2
  • 31
    • 0028762232 scopus 로고
    • Recognition of synthetic O-methyl, epimeric, and amino analogues of the acceptor alpha-L-FUCP-(1,2)-beta-D-GALP-OR by the blood-group A and B gene-specified glycosyltransferases
    • Lowary, T.L. & Hindsgaul, O. (1994). Recognition of synthetic O-methyl, epimeric, and amino analogues of the acceptor alpha-L-FUCP-(1,2)-beta-D-GALP-OR by the blood-group A and B gene-specified glycosyltransferases. Carbohydr. Res. 251, 33-67.
    • (1994) Carbohydr. Res. , vol.251 , pp. 33-67
    • Lowary, T.L.1    Hindsgaul, O.2
  • 32
    • 0030293156 scopus 로고    scopus 로고
    • Novel aspects of interactions between UDP-Gal and GlcNAc β-1,4galactosyltransferase: Transferability and remarkable inhibitory activity of UDP-(mono-O-methylated gal), UDP-fuc and UDP-man
    • Endo, T., Kajihara, Y., Kodama, H. & Hashimoto, H. (1996). Novel aspects of interactions between UDP-Gal and GlcNAc β-1,4galactosyltransferase: transferability and remarkable inhibitory activity of UDP-(mono-O-methylated gal), UDP-fuc and UDP-man. Bioorg. Med. Chem. 4, 1939-1948.
    • (1996) Bioorg. Med. Chem. , vol.4 , pp. 1939-1948
    • Endo, T.1    Kajihara, Y.2    Kodama, H.3    Hashimoto, H.4
  • 34
    • 0031105795 scopus 로고    scopus 로고
    • A chemo-enzymatic synthesis of UDP-(2-deoxy-2-fluoro)-galactose and evaluation of its interaction with galactosyltransferase
    • Hayashi, T., Murray, B.W., Wang, R. & Wong, C.-H. (1997). A chemo-enzymatic synthesis of UDP-(2-deoxy-2-fluoro)-galactose and evaluation of its interaction with galactosyltransferase. Bioorg. Med. Chem. 5, 497-500.
    • (1997) Bioorg. Med. Chem. , vol.5 , pp. 497-500
    • Hayashi, T.1    Murray, B.W.2    Wang, R.3    Wong, C.-H.4
  • 35
    • 0031039932 scopus 로고    scopus 로고
    • Mechanism of human alpha-1,3-fucosyltransferase V: Glycosidic cleavage occurs prior to nucleophilic attack
    • Murray, B.W., Wittmann, V., Burkart, M.D., Hung, S.-C. & Wong, C.-H. (1997). Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack. Biochemistry 36, 823-831.
    • (1997) Biochemistry , vol.36 , pp. 823-831
    • Murray, B.W.1    Wittmann, V.2    Burkart, M.D.3    Hung, S.-C.4    Wong, C.-H.5
  • 36
    • 0030915738 scopus 로고    scopus 로고
    • A search for pyrophosphate mimics for the development of substrates and inhibitors of glycosyltransferases
    • Wang, R., Steensma, D.H., Takaoka, Y., Yun, J.W., Kajimoto, T. & Wong, C.-H. (1997). A search for pyrophosphate mimics for the development of substrates and inhibitors of glycosyltransferases. Bioorg. Med. Chem. 5, 661-672.
    • (1997) Bioorg. Med. Chem. , vol.5 , pp. 661-672
    • Wang, R.1    Steensma, D.H.2    Takaoka, Y.3    Yun, J.W.4    Kajimoto, T.5    Wong, C.-H.6
  • 37
    • 0000097517 scopus 로고
    • Chemical-enzymatic synthesis and conformational analysis of sialyl lewis X and derivatives
    • Ichikawa, Y., et al., & Wong, C.-H. (1992). Chemical-enzymatic synthesis and conformational analysis of sialyl lewis X and derivatives. J. Am. Chem. Soc. 114, 9283-9298.
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 9283-9298
    • Ichikawa, Y.1    Wong, C.-H.2
  • 38
    • 0024355330 scopus 로고
    • Glycoproteins: What are the sugar chains for?
    • Paulson, J.C. (1983). Glycoproteins: what are the sugar chains for? Trends Biochem. Sci. 14, 272-276.
    • (1983) Trends Biochem. Sci. , vol.14 , pp. 272-276
    • Paulson, J.C.1
  • 39
    • 0025964452 scopus 로고
    • Carbohydrate differentiation antigens: Probable ligands for cell adhesion molecules
    • Feizi, T. (1991). Carbohydrate differentiation antigens: probable ligands for cell adhesion molecules. Trends Biochem. Sci. 16, 84-86.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 84-86
    • Feizi, T.1
  • 41
    • 0030822159 scopus 로고    scopus 로고
    • Chemoenzymatic preparation of novel cyclic imine sugars and rapid biological activity evaluation using electrospray mass spectrometry and kinetic analysis
    • in press
    • Takayama, S., et al., & Wong, C.-H. (1997). Chemoenzymatic preparation of novel cyclic imine sugars and rapid biological activity evaluation using electrospray mass spectrometry and kinetic analysis. J. Am. Chem. Soc., in press.
    • (1997) J. Am. Chem. Soc.
    • Takayama, S.1    Wong, C.-H.2
  • 42
    • 0029736391 scopus 로고    scopus 로고
    • Mechanism and specificity of human α-1,3-fucosyltransferase V
    • Murray, B.W., Takayama, S., Schultz, J. & Wong, C.-H. (1996). Mechanism and specificity of human α-1,3-fucosyltransferase V. Biochemistry 35, 11183-11195.
    • (1996) Biochemistry , vol.35 , pp. 11183-11195
    • Murray, B.W.1    Takayama, S.2    Schultz, J.3    Wong, C.-H.4
  • 43
    • 0029903008 scopus 로고    scopus 로고
    • Synthesis of lactosamine derivatives using β-D-galactosidase from bacillus circulans
    • Takayama, S., Shimazaki, M., Qiao, L. & Wong, C.-H. (1996). Synthesis of lactosamine derivatives using β-D-galactosidase from bacillus circulans. Bioorg. Med. Chem. Lett. 6, 1123-1126.
    • (1996) Bioorg. Med. Chem. Lett. , vol.6 , pp. 1123-1126
    • Takayama, S.1    Shimazaki, M.2    Qiao, L.3    Wong, C.-H.4


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