Novel Cell Imaging Techniques Show Induction of Apoptosis and Proliferation in Mesothelial Cells by Asbestos

American Journal of Respiratory Cell and Molecular Biology

Volumn 17, Issue 3, 1997, Pages 265-271

  Goldberg, Jonathan L ^a   Zanella, Christine L ^a   Janssen, Yvonne M W ^a   Timblin, Cynthia R ^a   Jimenez, Luis A ^a   Vacek, Pamela ^a   Taatjes, Douglas J ^a   Mossman, Brooke T ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1' ((4,4,7,7 TETRAMETHYL) 4,7 DIAZAUNDECAMETHYLENE)BIS 4 (3 METHYL 2,3 DIHYDRO(BENZO 1,3 OXAZOLE) 2 METHYLIDENE)QUINOLINIUM; 1,1'-((4,4,7,7-TETRAMETHYL)-4,7-DIAZAUNDECAMETHYLENE)BIS-4-(3-METHYL-2,3-DIHYDRO(BENZO-1,3-OXAZOLE)-2-METHYLIDENE)QUINOLINIUM; 4',6 DIAMIDINO 2 PHENYLINDOLE; BENZOXAZOLE DERIVATIVE; BIOTIN; BROXURIDINE; CARCINOGEN; CROCIDOLITE; DEOXYURIDINE PHOSPHATE; DNA FRAGMENT; EPIDERMAL GROWTH FACTOR; FLUORESCENT DYE; INDOLE DERIVATIVE; MITOGENIC AGENT; PHORBOL 13 ACETATE 12 MYRISTATE; QUINOLINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; APOPTOSIS; ARTICLE; CELL DIVISION; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; FISCHER 344 RAT; FLUORESCENCE MICROSCOPY; IMAGE CYTOMETRY; IMAGE PROCESSING; METHODOLOGY; PHYSIOLOGY; PLEURA; RAT; STAINING;

ANIMALS; APOPTOSIS; ASBESTOS, CROCIDOLITE; BENZOXAZOLES; BIOTIN; BROMODEOXYURIDINE; CARCINOGENS; CELL DIVISION; DEOXYURACIL NUCLEOTIDES; DNA FRAGMENTATION; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; FLUORESCENT DYES; IMAGE CYTOMETRY; IMAGE PROCESSING, COMPUTER-ASSISTED; INDOLES; MICROSCOPY, FLUORESCENCE; MITOGENS; PLEURA; QUINOLINIUM COMPOUNDS; RATS; RATS, INBRED F344; STAINING AND LABELING; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031226678     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.17.3.2991     Document Type: Article

References (25)

1. Manning, F. C. R., and S. R. Patierno. 1996. Apoptosis: inhibitor or instigator of carcinogenesis? Cancer Invest. 14:455-465.
2. Bardales, R. H., S.-S. Xie, R. F. Schaefer, and S.-M. Hsu. 1996. Apoptosis is a major pathway responsible for the resolution of type II pneumocytes in acute lung injury. Am. J. Pathol. 149:845-852.
3. Hagimoto, N., K. Kuwano, Y. Nomoto, R. Kunitake, and N. Hara. 1997. Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice. Am. J. Respir. Cell Mol. Biol. 16:91-101.
4. Majno, G., and I. Joris. 1995. Apoptosis, oncosis, and necrosis an overview of cell death. Am. J. Pathol. 146:3-15.
5. Gardner, A. M., F.-H. Xu, C. Fady, F. J. Jacoby, D. C. Duffey, Y. Tu, and A. Lichtenstein. 1997. Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide. Free Radic. Biol. Med. 22:73-83.
6. Kazzaz, J., J. Xu, T. A. Palaia, L. Mantell, A. M. Fein, and S. Horowitz. 1996. Cellular oxygen toxicity: oxidant injury without apoptosis. J. Biol. Chem. 271:15182-15186.
7. BéruBé, K. A., T. R. Quinlan, G. Moulton, D. Hemenway, P. O'Shaughnessy, P. Vacek, and B. T. Mossman. 1996. Comparative proliferative and histopathologic changes in rat lungs after inhalation of chrysotile or crocidolite asbestos. Toxicol. Appl. Pharmacol. 137:67-74.
8. Brody, A. R., and L. H. Overby. 1989. Incorporation of tritrated thymidine by epithelial and interstitial cells in bronchiolar-alveolar regions of asbestos-exposed rats. Am. J. Pathol. 134:133-140.
9. BéruBé, K. A., T. R. Quinlan, H. Fung, J. Magae, P. Vacek, D. J. Taatjes, and B. T. Mossman. 1996. Apoptosis is observed in mesothelial cells after exposure to crocidolite asbestos. Am. J. Respir. Cell Mol. Biol. 15:141-147.
10. 2 is directly related to increased proliferation and transformation of tracheal epithelial cells. Cancer Res. 55:2723-2726.
11. Iyer, R., R. F. Hamilton, L. Li, and A. Holian. 1996. Silica-induced apoptosis mediated via scavenger receptor in human alveolar macrophages. Toxicol. Appl. Pharmacol. 141:84-92.
12. Broaddus, V. C., L. Yang, L. M. Scavo, J. D. Ernst, and A. M. Boylan. 1996. Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen species. J. Clin. Invest. 98:2050-2059.
13. 3H]thymidine administered by injection or osmotic pump. Carcinogenesis 11:2245-2251.
14. Marsh, J. P., and B. T. Mossman. 1988. Mechanisms of induction of ornithine decarboxylase activity in tracheal epithelial cells by asbestiform minerals. Cancer Res. 48:709-714.
15. Zanella, C. L., J. Posada, T. R. Tritton, and B. T. Mossman. 1996. Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor. Cancer Res. 56:5334-5338.
16. Victor, I., P. Schwenger, W. Li, J. Schlessinger, and J. Vilcek. 1993. Tumor necrosis factor-induced activation and increased tyrosine phosphorylation of mitogen-activated protein (MAP) kinase in human fibroblasts. J. Biochem. 268:18994-18999.
17. Wendt, C. H., V. A. Polunovsky, M. S. Peterson, P. B. Bitterman, and D. H. Ingbar. 1994. Alveolar epithelial cells regulate the induction of endothelial cell apoptosis. Am. J. Physiol. 267:C893-C900.
18. Campbell, W. J., C. W. Huggins, and A. G. Wylie. 1980. Chemical and physical characterization of amosite, chrysolite, crocidolite, and nonfibrous tremolite for oral ingestion studies by the National Institute of Environmental Health Sciences. U.S. Bureau of Mines Report of Investigations, No. 8452, United States Government Printing Office, Washington, DC.
19. Tornusciolo, D. R. Z., R. E. Schmidt, and K. A. Roth. 1995. Simultaneous detection of TDT-mediated dUTP-biotin nick end-labeling (TUNEL)-positive cells and multiple immunohistochemical markers in single tissue sections. Biotechniques 19:800-805.
20. Sarih, M., V. Souvannavong, S. C. Brown, and A. Adam. 1993. Silica induces apoptosis in macrophages and the release of interleukin-1α and interleukin-1β. J. Leukocyte Biol. 54:407-413.
21. Hotz, M. A., J. Gong, F. Traganos, and Z. Darzynkiewicz. 1994. Flow cytometric detection of apoptosis: comparison of the assays of in situ DNA degradation and chromatin changes. Cytometry 15:237-244.
22. Ada, L., M. Crepin, C. Savin, and L. Israel. 1995. Sodium phenylacetate induces growth inhibition and Bcl-2 down-regulation and apoptosis in MCF7 ras cells in vitro and in nude mice. Cancer Res. 55:5156-5160.
23. Han, D. K. M., C. C. Haudenschild, M. K. Hong, B. T. Tinkle, M. B. Leon, and G. Liau. 1995. Evidence for apoptosis in human atherogenesis and in rat vascular injury model. Am. J. Pathol. 147:267-277.
24. Uhal, B. D., I. Joshi, A. L. True, S. Mundle, A. Raza, A. Pardo, and M. Selman. 1995. Fibroblasts isolated after fibrotic lung injury induce apoptosis of alveolar epithelial cells in vitro. Am. J. Physiol. 269:L819-L828.
25. Woodworth, C. D., B. T. Mossman, and J. E. Craighead. 1983. Induction of squamous metaplasia in organ cultures of hamster trachea by naturally occurring and synthetic fibers. Cancer Res. 43:4906-4912.