Molecular modeling of cerbb2 receptor dimerization: coiled-coil structure of wild and oncogenic transmembrane domainsstabilization by interhelical hydrogen bonds in the oncogenic form

Biopolymers - Nucleic Acid Sciences Section

Volumn 42, Issue 2, 1997, Pages 157-168

  Garnier, Norbert ^a   Genest, Daniel ^b   Duneau, Jean Pierre ^a   Genest, Monique ^a  

^a CNRS   (France)

^b UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

C erbb2 receptor; Coiled coil structure; Dimerization; Molecular modeling; Oncogenic transmembrane helices; Wild transmembrane helices

Indexed keywords

ASSOCIATION REACTIONS; COMPUTER SIMULATION; HYDROGEN BONDS; MECHANICS; MOLECULAR DYNAMICS; MOLECULAR ORIENTATION; MOLECULAR STRUCTURE;

COILED COIL STRUCTURE; DIMERIZATION; MOLECULAR MECHANICS; MOLECULAR MODELING; ONCOGENIC TRANSMEMBRANE HELICES; RECEPTOR; WILD TRANSMEMBRANE HELICES;

BIOLOGICAL MEMBRANES;

GROWTH FACTOR RECEPTOR;

ARTICLE; DIMERIZATION; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MODEL; PROTO ONCOGENE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; COMPUTER SIMULATION; DIMERIZATION; GLUTAMIC ACID; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, ERBB-2; RECOMBINANT PROTEINS;

EID: 0031214550     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0282(199708)42:2<157::aid-bip5>3.0.co;2-m     Document Type: Article

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