Acetic acid-friend or foe in anaerobic batch conversion of glucose to ethanol by Saccharomyces cerevisiae?

Chemical Engineering Science

Volumn 52, Issue 15, 1997, Pages 2653-2659

  Taherzadeh, Mohammad J ^a   Niklasson, Claes ^a   Lidén, Gunnar ^a  

^a CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

Author keywords

Ethanol; Glycerol; Growth energetics; PH; Yeast

Indexed keywords

ACETIC ACID; BATCH CELL CULTURE; BIOCONVERSION; BIOMASS; COMPOSITION EFFECTS; ETHANOL; GLUCOSE; GLYCEROL; GROWTH KINETICS; PH EFFECTS;

GROWTH ENERGETICS; SACCHAROMYCES CEREVISIAE;

YEAST;

EID: 0031214487     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2509(97)00080-8     Document Type: Article

References (35)

1. Axe, D. D. and Bailey, J. E. (1995) Transport of lactate and acetate through the energized cytoplasmic membrane of Escherichia coli. Biotechnol. Bioengng 47, 8-19.
2. Benthin, S., Nielsen, J. and Villadsen, J. (1991) Characterization and application of precise and robust flow-injection analysers for on-line measurement during fermentations. Anal. Chim. Acta 247, 45-50.
3. Cassio, F., Leao, C. and van Uden, N. (1987) Transport of lactate and other short-chain monocarboxylates in the yeast Saccharomyces cerevisiae. Appl. Environ. Microbiol. 53, 509-513.
4. Christensen, L., Schulze, U., Nielsen, J. and Villadsen, J. (1995) Acoustic off-gas analyser for bioreactors: Precision, accuracy and dynamics of detection. Chem. Engng Sci. 50, 2601-2610.
5. Dombek, K. M. and Ingram, L. O. (1987) Ethanol production during batch fermentation with Saccharomyces cerevisiae: changes in glycolytic enzymes and internal pH. Appl. Environ. Microbiol. 53, 1286-1291.
6. Duro, A. F. and Serrano, R. (1981) Inhibition of succinate production during yeast fermentation by deenergization of the plasma membrane. Curr. Microbiol. 6, 111-113.
7. Eraso, P., Mazon, M. J. and Gancedo, J. M. (1987) Internal acidification and cAMP increase are not correlated in Saccharomyces cerevisiae. Eur. J. Biochem. 165, 671-674.
8. Gottschalk, G. (1987) Control of product formation in anaerobes. Dechema-Monographs 105, 43-53.
9. Gutierrez, L. E., Annicchino, A. V. K. O., Lucatti, L. and Stipp, M. S. (1991) Effects of acetic acid on alcoholic fermentation. Arq. Biol. Tecnol. 34, 235-242.
10. Haukali, A. D. and Lie, S. (1971) Molar growth yields of yeasts in anaerobic batch cultures. J. Gen. Microbiol. 69, 135-141.
11. Kotyk, A. and Georghiou, G. (1991) Protonmotive force in yeasts - pH, buffer and species dependence. Biochem. Int. 24, 641-648.
12. Maesen, J. M. and Lako, E. (1952) The influence of acetate on the fermentation of baker's yeast, Biochim. Biophys. Acta 9 106-107.
13. Maiorella, B., Blanch, H. W. and Wilke, C. R. (1983) By-product inhibition effects on ethanolic fermentation by Saccharomyces cerevisiae. Biotechnol. Bioengng 25, 103-121.
14. Nordström, K. (1966) Yeast growth and glycerol formation. Acta Chem. Scand. 20, 6-15.
15. Oura, E. (1977) Reaction products of yeast fermentations. Proc. Biochem. 12, 19-21, 35.
16. Pampulha, M. E. and Loureiro-Dias, M. C. (1989) Combined effect of acetic acid, pH and ethanol on intracellular pH of fermenting yeast. Appl. Microbiol. Biotechnol. 31, 547-550.
17. Postma, E., Scheffers, W. A. and van Dijken, J. P. (1989) Kinetics of growth and glucose transport in glucose-limited chemostat cultures of Saccharomyces cerevisiae CBS 8066; Yeast 5, 159-165.
18. Ramos, J., Haro, R. and Rodriguez-Navarro, A. (1990) Regulation of potassium fluxes in Saccharomyces cerevisiae. Biochim. Biophys. Acta 1029, 211-217.
19. Ramos, S., Balbin, M., Raposo, M., Valle, E. and Pardo, L. A. (1989) The mechanism of intracellular acidification induced by glucose in Saccharomyces cerevisiae. J. Gen. Microbiol. 135, 2413-2422
20. van der Rest, M. E., Kamminga, A. H., Nakano, A., Anraku, Y., Poolman, B. and Konings, W. N. (1995) The plasma membrane of Saccharomyces cerevisiae structure, function, and biogenesis. Microbiol. Rev. 59, 304-322.
21. Samson, F. E., Katz, A. M. and Harris, D. L. (1955) Effects of acetate and other short-chain fatty acids on yeast metabolism. Archiv. Biochem. Biophys. 54, 406-423.
22. Schulze, U. (1995) Anaerobic physiology of Saccharomyces cerevisiae. Ph.D. thesis, Department of Biotechnology, The Technical University of Denmark.
23. Schulze, U., Lidén, G., Nielsen, J. and Villadsen, J. (1996) Physiological effects of nitrogen starvation in an anaerobic batch culture of Saccharomyces cerevisiae. Microbiol. 142, 2299-2310.
24. Seto-Young, D. and Perlin, D. S. (1991) Effect of membrane voltage on the plasma membrane hydrogen ion-ATPase of Saccharomyces cerevisiae. J. Biol. Chem. 266, 1383-1389.
25. Slavík, J. and Kotyk, A. (1984) Intracellular pH distribution and transmembrane pH profile of the yeast cell. Biochim. Biophys. Acta. 766, 679-684.
26. Stouthamer, A. H. and Bettenhaussen, C. (1973) Utilization of energy for growth and maintenance in continuous and batch cultures of microorganisms. Biochim. Biophys. Acta 301, 53-70.
27. Taherzadeh, M. J., Lidén, G., Gustafsson, L. and Niklasson, C. (1996) The effects of pantothenate deficiency and acetate addition on anaerobic batch fermentation of glucose by Saccharomyces cerevisiae, Appl. Microbiol. Biotechnol. 46, 176-182.
28. Taipa, M. A., Cabral, J. M. S. and Santos, H. (1993) Comparison of glucose fermentation by suspended and gel-entrapped yeast cells: an in vivo nuclear magnetic resonance study. Biotechnol. Bioengng 41, 647-653.
29. Valle, E., Bergillos, L., Gascon, S., Parra, F. and Ramos, S. (1986) Trehalase activation in yeasts is mediated by an internal acidification. Eur. J. Biochem. 154, 247-251.
30. Verduyn, C., Postma, E., Scheffers, W. A. and van-Dijken, J. P. (1990a) Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. J. Gen. Microbiol. 136, 305-319.
31. Verduyn, C., Postma, E., Scheffers, W. A. and van-Dijken, J. P. (1990b) Energetics of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. J. Gen. Microbiol. 136, 405-412.
32. Verduyn, C., Postma, E., Scheffers, W. A. and van Dijken, J. P. (1992) Effect of benzoic acid on metabolic fluxes in yeasts: a continuous-culture study on the regulation of respiration and alcoholic fermentation. Yeast 8, 501-507.
33. Viegas, C. E. and Sá-Correia (1995) Toxicity of octanoic acid in Saccharomyces cerevisiae at temperatures between 8.5 and 30°C. Enzyme Microbiol. Technol. 17, 826-831.
34. Warth, A. D. (1988) Effect of benzoic acid on growth yield of yeasts differing in their resistance to preservatives. Appl. Environ. Microbiol. 54, 2091-2095.
35. Watson, G. (1970) Effects of sodium chloride on steady-state growth and metabolism of Saccharomyces cerevisiae. J. Gen. Microbiol. 64, 91-99.