His381 of the rat CCKB receptor is essential for CCKB versus CCKA receptor antagonist selectivity

European Journal of Pharmacology

Volumn 296, Issue 1, 1996, Pages 97-106

  Jagerschmidt, Alexandre ^a   Guillaume Rousselet, Nathalie ^a   Vikland, Marie Louise ^a   Goudreau, Nathalie ^a   Maigret, Bernard ^b   Roques, Bernard Pierre ^a  

^a Laboratoire de Pharmacochimie   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

Author keywords

CCK receptor; Histidine; Mutation

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; 4 [[2 [2 [[(2 ADAMANTYLOXY)CARBONYL]AMINO] 3 (1H INDOL 3 YL) 2 METHYLPROPIONAMIDO] 1 PHENYLETHYL]AMINO] 4 OXOBUTYRIC ACID MEGLUMINE; ARGININE; BENZODIAZEPINE DERIVATIVE; CARBANILAMIDE DERIVATIVE; CHOLECYSTOKININ; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ OCTAPEPTIDE; CHOLECYSTOKININ RECEPTOR; DEVAZEPIDE; DRUG DERIVATIVE; HISTIDINE; INDOLE DERIVATIVE; MEGLUMINE; TETRAGASTRIN; CHOLECYSTOKININ A RECEPTOR ANTAGONIST; CHOLECYSTOKININ B RECEPTOR ANTAGONIST; CHOLECYSTOKININ RECEPTOR STIMULATING AGENT; LEUCINE; LINTITRIPT; N TERT BUTYLOXYCARBONYLTRYPTOPHYL[NEPSILON (2 METHYLPHENYLAMINOCARBONYL)LYSYL]ASPARTYL N METHYLPHENYLALANINAMIDE; PBC 264; PHENYLALANINE; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RAT; AMINO ACID SUBSTITUTION; ANIMAL CELL; BINDING COMPETITION; CELL CULTURE; COMPUTER MODEL; CONTROLLED STUDY; DRUG SELECTIVITY; GENETIC TRANSFECTION; LIGAND BINDING; MOLECULAR MODEL; MUTATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS;

ANIMALS; ARGININE; BASE SEQUENCE; BENZODIAZEPINONES; CHOLECYSTOKININ; DEVAZEPIDE; HISTIDINE; INDOLES; MEGLUMINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHENYLUREA COMPOUNDS; RATS; RECEPTOR, CHOLECYSTOKININ A; RECEPTOR, CHOLECYSTOKININ B; RECEPTORS, CHOLECYSTOKININ; SINCALIDE; TETRAGASTRIN;

EID: 0029671292     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00676-1     Document Type: Article

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