Mapping genes controlling hematocrit in the spontaneously hypertensive rat

Mammalian Genome

Volumn 8, Issue 6, 1997, Pages 387-389

  Pravenec, M ^a,b   Zidek, V ^a   Zdobinska, M ^a   Kren, V ^a,b   Krenova, D ^b   Bottger, A ^c   Van Zutphen, L F M ^c   Wang, J M ^d   St Lezin, E ^d  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN;

ANIMAL; ARTICLE; BLOOD PRESSURE; CHROMOSOME; CHROMOSOME MAP; GENETIC LINKAGE; GENETIC MARKER; GENETIC RECOMBINATION; GENETICS; HEMATOCRIT; HUMAN; METHODOLOGY; MOUSE; PHYSIOLOGY; RAT; RAT STRAIN; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; BLOOD PRESSURE; CHROMOSOME MAPPING; CHROMOSOMES; ERYTHROPOIETIN; GENETIC MARKERS; HEMATOCRIT; HUMANS; LINKAGE (GENETICS); MICE; RATS; RATS, INBRED SHR; RATS, INBRED STRAINS; RECOMBINATION, GENETIC;

ANIMALIA; RODENTIA;

EID: 0031153946     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900452     Document Type: Article

References (23)

1. Belknap JK, Mitchell SR, O'Toole LA, Helms ML, Crabbe JC (1996) Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombinant inbred mouse strains. Behav Genet 26, 149-160
2. Bottger A, van Lith HA, Kren V, Krenová D, Bílá V, Vorlícek J. Zídek V, Musilová A, Zdobinská M, Wang J-M, van Zutphen LFM, Kurtz TW, Pravenec M (1996) Quantitative trait loci influencing cholesterol and phospholipid phenotypes map to chromosomes that contain genes regulating blood pressure in the spontaneously hypertensitve rat. J Clin Invest 98, 856-862
3. Brushi G, Minari M, Bruschi ME, Tacinelli L, Milani B, Cavatorta A, Borghetti A (1986) Similarities of essential and spontaneous hypertension: volume and number of red blood cells. Hypertension 8, 983-989
4. Cirillo M, Lauranzi M, Trevisan M (1992) Hematocrit, blood pressure, and hypertension. The Gubbio population study. Hypertension 20, 319-326
5. Huang C, Davis G, Johns EJ (1993). Role of haematocrit in mediating the actions of chronic erythropoietin treatment on blood pressure and renal haemodynamics in the rat. Clin Sci 85, 717-724
6. Klingmuller U, Lorenz U, Cantley LC, Neel BG, Lodish HF (1995) Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 80, 729-738
7. Kozak CA, Bucan M, Goffinet A, Stephenson DA (1996) Mouse chromosome 5. Mamm Genome 6(Suppl), S97-S112
8. Letcher G, Bergentz SE, Bjure J, Wilhelmsen L (1966) Hematocrit, plasma protein, and viscosity in early hypertensive disease. Am Heart J 72, 165-176
9. Letcher RL, Chien S, Pickering TG, Laragh JH (1983) Elevated blood viscosity in patients with borderline essential hypertension. Hypertension 5, 757-762
10. Levan G, Szpirer J, Szpirer C, Klinga K, Hanson C, Islam Q (1991) The gene map of the Norway rat (Rattus norvegicus) and comparative mapping with mouse and man. Genomics 10, 699-718
11. Maes M, Scharpe S, Cooreman W, Wauters A, Neels H, Verkerk R, De Meyer F, D'Hondt P, Peeters D, Cosyns P (1995) Components of biological, including seasonal, variation in hematological measurements and plasma fibrinogen concentrations in normal humans. Experientia 51, 141-149
12. McDonough JR, James CG, Garrison GE, Stubb SC, Lichtman M, Hefelfinger DC (1965) The relationship of hematocrit to cardiovascular states of health in the Negro and white population of Evans County. Georgia. J Chronic Dis 18, 243-257
13. Moore KJ, Elliot RW (1996) Mouse chromosome 6. Mamm Genome 6(Suppl), S113-S134
14. Nagao M, Suga H, Okano M, Masuda S, Narita H, Ikura K, Sasaki R (1992) Nucleotide sequence of rat erythropoietin. Biochim Biophys Acta 1171, 99-102
15. Neumann PE (1990) Two-locus linkage analysis using recombinant inbred strains and Bayes' theorem. Genetics 126, 277-284
16. Plomin R, McClearn, GE (1993) Quantitative trait loci (QTL) analyses and alcohol-related behaviors. Behav Genet 23, 197-211
17. Pravenec M, Klír P, Kren V, Zicha J, Kuneš J (1989) An analysis of spontaneous hypertension in spontaneously hypertensive rats by means of new recombinant inbred strains. J Hypertens 7, 217-222
18. Pravenec M, Gauguier D, Schott J-J, Buard J, Kren V, Bílá V, Szpirer C, Szpirer J, Wang JM, Huang H, St. Lezin E, Spence MA, Flodman A, Printz M, Lathrop GM, Vergnaud G, Kurtz TW (1996) A genetic linkage map of the rat derived from recombinant inbred strains. Mamm Genome 7, 117-127
19. Sen S, Hoffman GC, Stowe NT, Smeby RR, Bumpus FM (1972) Erythrocytosis in spontaneously hypertensive rats. J Clin Invest 51, 710-714
20. Shoemaker CB, Mitsock LD (1986) Murine erythropoietin gene: cloning, expression, and human gene homology. Mol Cell Biol 6, 849-858
21. Smith S, Julius S, Jamerson K, Amerena J, Schork N (1994) Hematocrit levels and physiologic factors in relationship to cardiovascular risk in Tacumseh, Michigan. J Hypertens 12, 455-462
22. Wannamethee G, Shaper AG (1994) Haematocrit: relationship with blood lipids. blood pressure and other cardiovascular risk factors. Thromb Haemostasis 72, 58-64
23. Whitfield JB, Martin NG (1985) Genetic and environmental influences on the size and number of cells in the blood. Genet Epidemiol 2, 133-144