Expression of vasoactive intestinal polypeptide receptor mRNA and secretory regulation by vasoactive intestinal polypeptide in rat submandibular and sublingual salivary glands

Archives of Oral Biology

Volumn 42, Issue 3, 1997, Pages 197-204

  Takai, N ^a   Yoshida, Y ^a   Shida, T ^a   Kondo, E ^a   Ueda, Y ^a   Kiyama, H ^b   Tohyama, M ^c  

^a OSAKA DENTAL UNIVERSITY   (Japan)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

in situ hybridization; neurotransmitter; parasympathetic nerve; salivary gland; salivary secretion; VIP

Indexed keywords

DRUG DERIVATIVE; HORMONE ANTAGONIST; MESSENGER RNA; SALIVA PROTEIN; SERMORELIN; SOMATOTROPIN RELEASING HORMONE (1-29)-AMIDE, N-AC-TYR(1)-PHE(2)-; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR;

ANIMAL; ANIMAL TISSUE; ARTICLE; CHORDA TYMPANI; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ELECTROSTIMULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; INNERVATION; MALE; METABOLISM; NERVE FIBER; NONHUMAN; PHYSIOLOGY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; RAT STRAIN; SALIVATION; SECRETION; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND;

ANIMALS; CHORDA TYMPANI NERVE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; GENE EXPRESSION REGULATION; HORMONE ANTAGONISTS; IN SITU HYBRIDIZATION; MALE; NERVE FIBERS; RATS; RATS, WISTAR; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE; RNA, MESSENGER; SALIVARY PROTEINS; SECRETORY RATE; SERMORELIN; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0031105677     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9969(97)00002-2     Document Type: Article

References (30)

1. Asztèly A., Ekman R., Tobin G. and Ekström J. (1996) Depletion of vasoactive intestinal peptide and substance P in parotid glands of atropinized rats during reflex secretion. Exp. Physiol. 81, 297-303.
2. Bloom S. R. and Edwards A. V. (1980) Vasoactive intestinal polypeptide in relation to atropine-resistant vasodilation in the submaxillary gland of the cat. J. Physiol (Lond). 300, 41-53.
3. Bobyock E. and Chernick W. S. (1989) Vasoactive intestinal peptide interacts with alpha-adrenergic cholinergic-, and substance P-mediated responses in rat parotid and submandibular glands. J. dent. Res. 68, 1489-1494.
4. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
5. Duner-Engström M. D., Larsson O., Fredholm B. B., Lundblad L., Fahrenkrug J. M. and Lundberg J. M. (1992) Effects of acute and long-term atropine treatment on levels, release and response to VIP and PHI in the submandibular gland of cat and rat. Acta Physiol. Scand. 146, 357-367.
6. Ekström J., Brodin E., Ekman R., Håkanson R., Månsson B. and Tobin G. (1985) Depletion of neuropeptides in rat parotid glands and declining atropine-resistant salivary secretion upon continuous parasympathetic nerve stimulation. Regul. Pept. 11, 353-359.
7. Ekström J., Ekman R., Luts A., Sundler F. and Tobin G. (1996) Neuropeptide Y in salivary glands of the rat: origin, release and secretory effects. Regul. Pept. 61, 125-134.
8. Ekström J., Månsson B., Orgart L. and Tobin G. (1988) Non-adrenergic, non-cholinergic salivary secretion in the ferret. Q. J. exp. Physiol. 73, 163-173.
9. Ekström J., Månsson B. and Tobin G. (1983) Vasoactive intestinal peptide evoked secretion of fluid and protein from rat salivary glands and the development of supersensitivity. Acta Physiol. Scand. 119, 169-175.
10. Ekström J., Månsson B. and Tobin G. (1987) Non-adrenergic, non-cholinergic parasympathetic secretion in the rat submaxillary and sublingual glands. Pharmacol. Toxicol. 60, 284-287.
11. Ekström J., Nilsson B-O, and Rosengren E. (1989) Substance P and vasoactive intestinal peptide influence polyamine metabolism in salivary glands of the rat. Acta Physiol. Scand. 136, 427-433.
12. Iwabuchi Y. and Masuhara T. (1994) Effects on vasoactive intestinal peptide and its homologues on the acetyl-choline-mediated secretion of fluid and protein from the rat submandibular gland. Gen. Pharmac. 26, 961-970.
13. Johansson O. and Lundberg J. M. (1981) Ultrastructural localization of VIP-like immunoreactivity in large densecore vesicles on 'cholinergic-type' nerve terminals in cat exocrine glands. Neuroscience. 5, 847-862.
14. Lundberg J. M., Änggard A. and Fahrenkrug J. (1982) Complementary role of vasoactive intestinal peptide (VIP) and acetylcholine for cat submandibular gland blood flow and secretion. Acta. Physiol. Scand. 114, 329-337.
15. Reid A. M. and Titchen D. A. (1988) Atropine-resistant secretory responses of the ovine parotid gland to reflex and direct parasympathetic stimulation. Q. J. Exp Physiol. 73, 413-424.
16. Reid A. M. and Heywood L. H. (1988) A comparison of the effects of vasoactive intestinal polypeptide on secretion from the submaxillary gland of the sheep and pig. Regul Pept. 20, 211-221.
17. Rostrad O. P., Wanke I., Coy D. H., Fornier A. and Huang M. (1990) Selectivity for binding of peptide analogs to vascular receptors for vasoactive intestinal peptide. Molec. Pharmacol. 37, 971-977.
18. Shimizu T. and Taira N. (1979) Assessment of the effect of vasoactive intestinal peptide (VIP) on blood flow-through and salivation of the dog salivary gland in comparison with those of secretin, glucagon and acetylcholine. Br. J. Pharmacol. 65, 683-687.
19. Sundler F., Ekblad E., Grunditz T., Håkanson R. and Uddman R. (1988) Vasoactive intestinal peptide in the peripheral nervous system. Ann. N. Y. Acad Sci. 527, 143-167.
20. Takai N., Yoshida Y. and Kakudo Y. (1982) Technique for collection of saliva from the three major salivary glands of individual rats. J. Osaka dent. Univ. 16, 17-23.
21. Takai N., Yoshida Y. and Kakudo Y. (1983) Secretion and re-absorption of glucose in rat submandibular and sublingual saliva. J. dent. Res. 62, 1022-1025.
22. Tichen D. A. and Reid A. M. (1990) Non-adrenergic, non-cholinergic control of salivary gland function In Epithelial Secretion of Water and Electrolytes (Eds. Young J. A. and Wong P. Y.), pp. 219-228. Springer-Verlag, Berlin.
23. Tobin G., Ekström J., Bloom S. R. and Edward A. V. (1991) Atropine-resistant submandibular responses to stimulation of the parasympathetic innervation in the anaesthetized ferret. J. Physiol (Lond). 437, 327-339.
24. Tobin G., Luts A., Sundler F. and Ekström J. (1990a) VIP-containing nerve fibres in the submandibular gland of dog and protein secretion in vitro in response to VIP. Regul. Pept. 29, 173-177.
25. Tobin G., Luts A., Sundler F. and Ekström J. (1990b) Peptidergic innervation of the major salivary glands of the ferret. Peptides. 11, 863-867.
26. Turner J. T. and Bylund D. B. (1987) Characterization of the vasoactive intestinal peptide receptor in rat submandibular gland: radioligand binding assay in membrane preparations. J. Pharmacol. exp. Ther. 242, 873-881.
27. Turner J. T., Bollinger D. W. and Toews M. L. (1988) Vasoactive intestinal peptide receptor/adenylate cyclase system. Differences between agonist- and protein kinase C-mediated desensitization and further evidence for receptor internalization. J. Pharmacol. exp. Ther. 247, 417-423.
28. Turner J. T. and Camden J. M. (1992) Regulation of secretion by vasoactive intestinal peptide in isolated perfused rat submandibular glands. Archs oral Biol. 37, 281-287.
29. Uddman R., Fahrenkrug J., Malm L., Alumets J., Håkanson R. and Sundler F. (1980) Neuronal VIP in salivary glands: Distribution and release. Acta Physiol. Scand. 110, 31-38.
30. 2 as a VIP antagonist. Endocrinology. 116, 2643-2649.