Molecular properties of the proteasome activator PA28 family proteins and γ-interferon regulation

Genes to Cells

Volumn 2, Issue 3, 1997, Pages 195-211

  Tanahashi, Nobuyuki ^a,i   Yokota, Kin Ya ^a   Ahn, Joon Young ^b   Chung, Chin Ha ^b   Fujiwara, Tsutomu ^c   Takahashi, Ei Ichi ^c   DeMartino, George N ^d   Slaughter, Clive A ^e   Toyonaga, Tetsushi ^f   Yamamura, Ken Ichi ^f   Shimbara, Naoki ^g,i   Tanaka, Keiji ^h,i  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b Seoul National University   (South Korea)

^c Otsuka GEN Research Institute   (Japan)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f KUMAMOTO UNIVERSITY   (Japan)

^g SUMITOMO ELECTRIC INDUSTRIES LTD   (Japan)

^h TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

ⁱ JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; GAMMA INTERFERON; KI ANTIGEN; MESSENGER RNA; MUSCLE PROTEIN; NUCLEAR PROTEIN; PROTEASOME; PROTEIN; PSME1 PROTEIN, HUMAN; PSME1 PROTEIN, MOUSE; PSME2 PROTEIN, MOUSE; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHROMOSOME 17; CHROMOSOME MAP; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; MALE; MOLECULAR GENETICS; MOUSE; NON-PROGRAMMATIC; PHYSIOLOGY; SOUTHERN BLOTTING; TRANSGENIC MOUSE;

NON-PROGRAMMATIC;

AMINO ACID SEQUENCE; ANIMALS; AUTOANTIGENS; BLOTTING, SOUTHERN; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 17; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERFERON TYPE II; MALE; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; RECOMBINANT PROTEINS; RNA, MESSENGER;

EID: 0031085545     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1997.d01-308.x     Document Type: Article

References (49)

1. Ahn, J.Y., Tanahashi, N., Akiyama, K., et al. (1995) Primary structures of two homologous subunits of PA28, a γ-interferon-inducible protein activator of the 20S proteasome. FEBS Lett. 366, 37-42.
2. Ahn, K., Erlander, M., Leturcq, D., Peterson, P.A., Früh, K. & Yang, Y. (1996) In vivo characterization of the proteasome regulator PA28. J. Biol. Chem. 271, 18237-18242.
3. Aki, M., Shimbara, N., Takashina, M., et al. (1994) Interferon-γ induces different subunit organizations and functional diversity of proteasomes. J. Biochem. 115, 257-269.
4. Akiyama, K., Yokota, K., Kagawa, S., et al. (1994) cDNA cloning and interferon-γ down-regulation of proteasomal subunits X and Y. Science 265, 1231-1234.
5. Belich, M.P., Glynne, R.J., Senger, G., Sheer, D. & Trowsdale, J. (1994) Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins. Curr. Biol. 4, 769-776.
6. Billiau, A. (1996) Interferon-γ: Biology and role in pathogenesis. Adv. Immunol. 62, 61-130.
7. Boes, B., Hengel, H., Ruppert, T., Multhaup, G., Koszinowski, U.H. & Kloetzel, P.-M. (1994) Interferon-γ stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes. J. Exp. Med. 179, 901-909.
8. Ciechanover, A. (1994) The ubiquitin-proteasome proteolytic pathway. Cell 79, 13-21.
9. Coux, O., Tanaka, K. & Goldberg, A.L. (1996) Structure and functions of the 20S and 26S proteasomes. Annu. Rev. Biochem. 65, 801-847.
10. DeMartino, G.N. & Slaughter, C. (1993) Regulatory proteins of the proteasome. Enzyme Protein 47, 314-324.
11. Dick, T.P., Ruppert, T., Groettrup, M., et al. (1996) Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands. Cell 86, 253-262.
12. Driscoll, J., Brown, M.G., Finley D. & Monaco, J.J. (1993) MHC-linked LMP gene products specifically alter peptidase activities of the proteasome. Nature 365, 262-264.
13. Dubiel, W., Pratt, G., Ferrell, K. & Rechsteiner, M. (1992) Purification of an 11S regulator of the multicatalytic protease. J. Biol. Chem. 267, 22369-22377.
14. Früh, K., Gossen, M., Wang, K., Bujard, H., Peterson, P.A. & Yang, Y. (1994) Displacement of housekeeping proteasome subunits by MHC-encoded LMPS: a newly discovered mechanism for modulating the multicatalytic proteinase complex. EMBO J. 13, 3236-3244.
15. Gaczynska, M., Rock, K.L. & Goldberg, A.L. (1993) γ-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature 365, 264-267.
16. Gray C.W., Slaughter, C.A. & DeMartino, G.N. (1994) PA28 activator protein forms regulatory caps on proteasome stacked rings. J. Mol. Biol. 236, 7-15.
17. Groettrup, M., Ruppert, T., Kuehn, L., et al. (1995) There interferon-γ-inducible 11S regulator (PA28) and the LMP2/LMP7 subunits govern the peptide production by the 20S proteasome in vitro. J. Biol. Chem. 270, 23808-23815.
18. Groettrup, M., Soza, A., Eggers, M., et al. (1996) A role of the proteasome regulator PA28α in antigen presentation. Nature 381, 166-168.
19. Heemels, M.T. & Ploegh, H. (1995) Generation, translocation, and presentation of MHC class I-restricted peptides. Annu. Rev. Biochem. 64, 463-491.
20. Hershko, A. & Ciechanover, A. (1992) The ubiquitin system for protein degradation. Annu. Rev. Biochem. 61, 761-807.
21. Hilt, W. & Wolf D.H. (1995) Proteasomes: destruction as a programme. Trends Biochem. Sci. 21, 96-102.
22. Hisamatsu, H., Shimbara, N., Saito, Y., et al. (1996) Newly identified pair of proteasomal subunits regulated reciprocally by interferon-γ. J. Exp. Med. 183, 1807-1816.
23. Hochstrasser, M. (1997) Ubiquitin-dependent protein degradation. Annul. Rev. Genet. 30, 405-439.
24. Honoré, B., Leffers, H., Madsen, P. & Celis, J.E. (1993) Interferon-γ up-regulates a unique set of proteins in human keratinocytes: Molecular cloning and expression of the cDNA encoding the RGD-sequence-containing protein IGUP I-5111. Eur. J. Biochem. 218, 421-430.
25. Kanayama, H., Tamura, T., Ugai, S., et al. (1992) Demonstration that a human 26S proteolytic complex consists of a proteasome and multiple associated protein components and hydrolyzes ATP and ubiquitin-ligated proteins by a closely linked mechanism. Eur. J. Biochem. 206, 567-578.
26. Kasahara, M., Hayashi, M., Tanaka, K., et al. (1996) Chromosomal localization of the proteasome Z gene reveals an ancient chromosomal duplication involving the major histocompatibility complex. Proc. Natl. Acad. Sci. USA 93, 9096-9101.
27. Lichter, P., Ledbetter, S.A., Ledbetter, D.H., & Ward, D.C. (1990) Fluorescence in situ hybridization with Alu and L1 polymerase chain reaction probes for rapid characterization of human chromosomes in hybrid cell lines. Proc. Natl. Acad. Sci. USA 87, 6634-6638.
28. Lupas, A., Koster, A.J. & Baumeister, W. (1993) Structural features of 26S and 20S proteasomes. Enzyme Protein 47, 252-273.
29. Ma, C.P., Slaughter, C.A. & DeMartino, G.N. (1992) Identification, purification, and characterization of a protein activator (PA28) of the 20S proteasome (macropain). J. Biol. Chem. 267, 10515-10523.
30. Monaco, J.J. & Nandi, D. (1995) The genetics of proteasomes and antigen processing. Annul Rev. Genet. 29, 729-754.
31. Mott, J.D., Pramanik, B.C., Moomaw, C.R., Afendis, S.J., DeMartino, G.N. & Slaughter, C.A. (1994) PA28, an activator of the 20S proteasome, is composed of two nonidentical but homologous subunits. J. Biol. Chem. 269, 31466-31471.
32. Nikaido, T., Shimada, K., Shibata, M., et al. (1990) Cloning and nucleotide sequence of cDNA for Ki antigen, a highly conserved nuclear protein detected with sera from patients with systemic lupus erythromatosus. Clin. Exp. Immunol. 79, 209-214.
33. Orino, E., Tanaka, K., Tamura, T., Sone, S., Ogura, T. & Ichihara, A. (1991) ATP-dependent reversible association of proteasomes with multiple protein components to form 26S complexes that degrade ubiquitinated proteins in human HL-60 cells. FEBS Lett. 284, 206-210.
34. Peters, J.M. (1994) Proteasomes: protein degradation machines of the cells. Trends Biochem. Sci. 19, 377-382.
35. Realini, C., Dubiel, W., Pratt, G., Ferrell, K. & Rechsteiner, M. (1994) Molecular cloning and expression of a γ-interferon-inducible activator of the multicatalytic protease. J. Biol. Chem. 269, 20727-20732.
36. Rechsteiner, M., Hoffman, L. & Dubiel, W. (1993) The multicatalytic and 26S proteases. J. Biol. Chem. 268, 6065-6068.
37. Rivett, A.J. (1993) Proteasomes: multicatalytic proteinase complexes. Biochem. J. 291, 1-10.
38. Song, X., Mott, J.D., von Kampen, J., et al. (1996) A model for the quaternary structure of the proteasome activator PA28. J. Biol. Chem. 271, 26410-26417.
39. Takahashi, E., Yamauchi, M., Tsuji, H., Hitomi, A., Meuth, M. & Hori, T. (1991) Chromosome mapping of the human cytidine-5′-triphosphate (CTPS) genes to band 1p34.1-p34.3 by fluorescence in situ hybridization. Hum. Genet. 88, 119-121.
40. Tamura, T., Nagy I., Lupas, A., et al. (1995) The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus sp. strain NI86/21. Curr. Biol. 5, 766-774.
41. Tanaka, K., Yoshimura, T., Kumatori, A., et al. (1988) Proteasomes (multi-protease complexes) as 20S ring-shaped particles in a variety of eukaryotic cells. J. Biol. Chem. 263, 16209-16217.
42. Tanaka, K., Yoshimura, T., Tamura, T., Fujiwara, T., Kumatori, A. & Ichihara, A. (1990) Possible mechanism of nuclear translocation of proteasomes. FEBS Lett. 271, 41-46.
43. Tanaka, K., Tanahashi, N., Tsurumi, C., Yokota, K. & Shimbara, N. (1997) Proteasomes and antigen processing. Adv. Immunol., in press.
44. Toyonaga, T., Hino, O., Sugai, S., et al. (1994) Chronic active hepatitis in transgenic mice expressing interferon-γ in the liver. Proc. Natl. Acad. Sci. USA 91, 614-618.
45. Tsurumi, C., DeMartino, G.N., Slaughter, C.A., Shimbara, N. & Tanaka, K. (1995) cDNA cloning of p40 a regulatory subunit of the human 26S proteasome, and a homolog of Mov-34 gene product. Biochem. Biophys. Res. Commun. 210, 600-608.
46. Tsurumi, C., Shimizu, Y., Saeki, M., et al. (1996) cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type 1 TNF receptor associated protein TRAP-2/55.11. Eur. J. Biochem. 239, 912-921.
47. Ustrell, V., Pratt, G. & Rechsteiner, M. (1995) Effects of interferon-γ and major histocompatibility complex-encoded subunits on peptidase activities of human multicatalytic proteases. Proc. Natl. Acad. Sci. USA 92, 584-588.
48. York, I.A. & Rock, K.L. (1996) Antigen processing and presentation by the class I major histocompatibility complex. Annu. Rev. Immunol. 14, 369-397.
49. Yoshimura, T., Kameyama, K., Takagi, T., et al. (1993) Molecular characterization of the '26S' proteasome complex from rat liver. J. Struct. Biol. 111, 200-211.