메뉴 건너뛰기




Volumn 10, Issue 1, 1997, Pages 87-97

Treatment with a chimeric CD4 monoclonal antibody is associated with a relative loss of CD4+/CD45RA+ cells in patients with rheumatoid arthritis

Author keywords

CD4 monoclonal antibodies; human anti monoclonal antibodies; lymphokine production; rheumatoid arthritis; T cells

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; CHIMERIC ANTIBODY; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 4; MONOCLONAL ANTIBODY;

EID: 0031081473     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1996.0113     Document Type: Article
Times cited : (19)

References (40)
  • 1
    • 0026752620 scopus 로고
    • The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis (editorial)
    • Panayi G.S., Lanchbury J.S., Kingsley G.H. The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis (editorial). Arthritis Rheum. 35:1992;729-735.
    • (1992) Arthritis Rheum. , vol.35 , pp. 729-735
    • Panayi, G.S.1    Lanchbury, J.S.2    Kingsley, G.H.3
  • 2
    • 0023272173 scopus 로고
    • The role of the murine L3T4 molecule in T cell activation: Differential effects of anti-L3T4 on activation by monoclonal anti-receptor antibodies
    • Janeway C.A., Haque S., Smith L.A., Saizawa K. The role of the murine L3T4 molecule in T cell activation: differential effects of anti-L3T4 on activation by monoclonal anti-receptor antibodies. J. Mol. Cell. Immunol. 3:1987;121-131.
    • (1987) J. Mol. Cell. Immunol. , vol.3 , pp. 121-131
    • Janeway, C.A.1    Haque, S.2    Smith, L.A.3    Saizawa, K.4
  • 5
    • 0026613778 scopus 로고
    • Reprogramming the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies
    • Cobbold S.P., Qin S., Leong L.Y.W., Martin G., Waldmann H. Reprogramming the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies. Immunol. Rev. 129:1992;165-201.
    • (1992) Immunol. Rev. , vol.129 , pp. 165-201
    • Cobbold, S.P.1    Qin, S.2    Leong, L.Y.W.3    Martin, G.4    Waldmann, H.5
  • 6
    • 0022361703 scopus 로고
    • Prevention of Type II collagen-induced arthritis by in vivo treatment with anti-L3T4
    • Ranges G.E., Sriram S., Cooper S.M. Prevention of Type II collagen-induced arthritis by in vivo treatment with anti-L3T4. J. Exp. Med. 162:1985;1105-1110.
    • (1985) J. Exp. Med. , vol.162 , pp. 1105-1110
    • Ranges, G.E.1    Sriram, S.2    Cooper, S.M.3
  • 10
    • 0025980476 scopus 로고
    • Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody
    • Horneff G., Burmester G.R., Emmrich F., Kalden J.R. Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody. Arthritis Rheum. 34:1991;129-140.
    • (1991) Arthritis Rheum. , vol.34 , pp. 129-140
    • Horneff, G.1    Burmester, G.R.2    Emmrich, F.3    Kalden, J.R.4
  • 14
    • 0029115051 scopus 로고
    • A randomized, double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis
    • Van der Lubbe P.A., Dijkmans B.A.C., Markusse H.M., Nässander U., Breedveld F.C. A randomized, double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis. Arthritis Rheum. 38:1995;1097-1106.
    • (1995) Arthritis Rheum. , vol.38 , pp. 1097-1106
    • Van Der Lubbe, P.A.1    Dijkmans, B.A.C.2    Markusse, H.M.3    Nässander, U.4    Breedveld, F.C.5
  • 15
    • 1842290017 scopus 로고
    • Minimal efficacy of a depleting chimeric anti-CD4 (cM-T412) in treatment of patients with refractory rheumatoid arthritis receiving concomitant methotrexate (abstract)
    • Moreland L., Pratt P., Mayes M., Postlethwaite A., Weisman M., Schnitzer T., Lightfoot R., Calabrese L., Koopman W. Minimal efficacy of a depleting chimeric anti-CD4 (cM-T412) in treatment of patients with refractory rheumatoid arthritis receiving concomitant methotrexate (abstract). Arthritis Rheum. 36 (suppl 9):1993.
    • (1993) Arthritis Rheum. , vol.369
    • Moreland, L.1    Pratt, P.2    Mayes, M.3    Postlethwaite, A.4    Weisman, M.5    Schnitzer, T.6    Lightfoot, R.7    Calabrese, L.8    Koopman, W.9
  • 16
    • 0026656620 scopus 로고
    • Treatment of rheumatoid arthritis with single dose or weekly pulses of chimaeric anti-CD4 monoclonal antibody
    • Choy E.H.S., Chikanza I.C., Kingsley G.H., Corrigall V., Panayi G.S. Treatment of rheumatoid arthritis with single dose or weekly pulses of chimaeric anti-CD4 monoclonal antibody. Scand. J. Immunol. 36:1992;291-298.
    • (1992) Scand. J. Immunol. , vol.36 , pp. 291-298
    • Choy, E.H.S.1    Chikanza, I.C.2    Kingsley, G.H.3    Corrigall, V.4    Panayi, G.S.5
  • 17
    • 0027093377 scopus 로고
    • Treatment of rheumatoid arthritis with anti-CD4 monoclonal antibody: Open study of 25 patients with the B-F5 clone
    • Wendling D., Racadot E., Morel-Fourrier B., Wijdenes J. Treatment of rheumatoid arthritis with anti-CD4 monoclonal antibody: open study of 25 patients with the B-F5 clone. Clin. Rheumatol. 11:1992;542-547.
    • (1992) Clin. Rheumatol. , vol.11 , pp. 542-547
    • Wendling, D.1    Racadot, E.2    Morel-Fourrier, B.3    Wijdenes, J.4
  • 19
    • 84945008882 scopus 로고
    • Immunosuppression by anti-CD4 treatment in vivo. Cellular and humoral responses to alloantigens
    • Weyand C.M., Goronzy J., Swartztrauber K., Fathman C.G. Immunosuppression by anti-CD4 treatment in vivo. Cellular and humoral responses to alloantigens. Transplantation. 47:1989;1039-1042.
    • (1989) Transplantation , vol.47 , pp. 1039-1042
    • Weyand, C.M.1    Goronzy, J.2    Swartztrauber, K.3    Fathman, C.G.4
  • 20
    • 0023244764 scopus 로고
    • In vivo immunomodulation by monoclonal anti-L3T4. 1. Effects on humoral and cell-mediated immune response
    • Ranges G.E., Cooper S.M., Sriram S. In vivo immunomodulation by monoclonal anti-L3T4. 1. Effects on humoral and cell-mediated immune response. Cell. Immunol. 106:1987;163-173.
    • (1987) Cell. Immunol. , vol.106 , pp. 163-173
    • Ranges, G.E.1    Cooper, S.M.2    Sriram, S.3
  • 21
    • 0022642908 scopus 로고
    • Induction of tolerance by monoclonal antibody therapy
    • Benjamin R.J., Waldman H. Induction of tolerance by monoclonal antibody therapy. Nature. 320:1986;449-451.
    • (1986) Nature , vol.320 , pp. 449-451
    • Benjamin, R.J.1    Waldman, H.2
  • 22
    • 0022496831 scopus 로고
    • Induction of tolerance by administration of monoclonal antibody to L3T4
    • Gutstein N.L., Seaman W.E., Scott J.H., Wofsy D. Induction of tolerance by administration of monoclonal antibody to L3T4. J. Immunol. 137:1986;1127-1133.
    • (1986) J. Immunol. , vol.137 , pp. 1127-1133
    • Gutstein, N.L.1    Seaman, W.E.2    Scott, J.H.3    Wofsy, D.4
  • 23
    • 0026509448 scopus 로고
    • Kinetics of anti-CD4-induced T helper cell depletion and inhibition of function: Activation by the CD3 pathway inhibits anti-CD4-mediated T cell elimination and down-regulation of cell surface CD4
    • Jamali I., Field E.H., Fleming A., Cowdery J.S. Kinetics of anti-CD4-induced T helper cell depletion and inhibition of function: activation by the CD3 pathway inhibits anti-CD4-mediated T cell elimination and down-regulation of cell surface CD4. J. Immunol. 148:1992;1613-1619.
    • (1992) J. Immunol. , vol.148 , pp. 1613-1619
    • Jamali, I.1    Field, E.H.2    Fleming, A.3    Cowdery, J.S.4
  • 24
    • 0028212484 scopus 로고
    • Effect of anti-CD4 on CD4 subsets. I. Anti-CD4 preferentially deletes resting naive CD4 cells and spares activated CD4 cells
    • Chase J.H., Cowdery J.S., Field E.H. Effect of anti-CD4 on CD4 subsets. I. Anti-CD4 preferentially deletes resting naive CD4 cells and spares activated CD4 cells. J. Immunol. 152:1994;405-412.
    • (1994) J. Immunol. , vol.152 , pp. 405-412
    • Chase, J.H.1    Cowdery, J.S.2    Field, E.H.3
  • 25
    • 0026663510 scopus 로고
    • Altered IFN-γ and IL-4 pattern lymphokine secretion in mice partially depleted of CD4 T cells by anti-CD4 monoclonal antibody
    • Field E.H., Rouse T.M., Fleming A.L., Jamali I., Cowdery J. Altered IFN-γ and IL-4 pattern lymphokine secretion in mice partially depleted of CD4 T cells by anti-CD4 monoclonal antibody. J. Immunol. 149:1992;1131-1137.
    • (1992) J. Immunol. , vol.149 , pp. 1131-1137
    • Field, E.H.1    Rouse, T.M.2    Fleming, A.L.3    Jamali, I.4    Cowdery, J.5
  • 26
    • 0021848452 scopus 로고
    • Monoclonal antibodies to human immune interferon and their use in a sensitive solid-phase ELISA
    • Van der Meide P.H., Dubbeld M., Schellekens H. Monoclonal antibodies to human immune interferon and their use in a sensitive solid-phase ELISA. J. Imm. Methods. 79:1985;293-305.
    • (1985) J. Imm. Methods , vol.79 , pp. 293-305
    • Van Der Meide, P.H.1    Dubbeld, M.2    Schellekens, H.3
  • 28
    • 0009732874 scopus 로고
    • The importance of dose and dosing regimen of anti-CD4 monoclonal antibody in the treatment of rheumatoid arthritis (abstract)
    • Choy E.H.S., Pitzalis C., Bijl J.A., Kingsley G.H., Panayi G.S. The importance of dose and dosing regimen of anti-CD4 monoclonal antibody in the treatment of rheumatoid arthritis (abstract). Arthritis Rheum. 36 (suppl 9):1993.
    • (1993) Arthritis Rheum. , vol.369
    • Choy, E.H.S.1    Pitzalis, C.2    Bijl, J.A.3    Kingsley, G.H.4    Panayi, G.S.5
  • 29
    • 0023932748 scopus 로고
    • The progression of inflammation in established collagen-induced arthritis can be altered by treatments with immunological or pharmacological agents which inhibit T cell activities
    • Hom J.T., Butler L.D., Riedl P.E., Bendele A.M. The progression of inflammation in established collagen-induced arthritis can be altered by treatments with immunological or pharmacological agents which inhibit T cell activities. Eur. J. Immunol. 18:1988;881-888.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 881-888
    • Hom, J.T.1    Butler, L.D.2    Riedl, P.E.3    Bendele, A.M.4
  • 31
    • 0025275127 scopus 로고
    • Monoclonal antibodies and arthritis. Agents and Actions
    • Billingham M.E.J., Hicks C., Carney S. Monoclonal antibodies and arthritis. Agents and Actions. Eur. J. Immunol. 29:1990;77-87.
    • (1990) Eur. J. Immunol. , vol.29 , pp. 77-87
    • Billingham, M.E.J.1    Hicks, C.2    Carney, S.3
  • 32
    • 0028226982 scopus 로고
    • Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis
    • Williams R.O., Mason L.J., Feldmann M., Maini R.N. Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis. Proc. Natl. Acad. Sci. USA. 91:1994;2762-2766.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2762-2766
    • Williams, R.O.1    Mason, L.J.2    Feldmann, M.3    Maini, R.N.4
  • 34
    • 0022400673 scopus 로고
    • Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice
    • Titus R.G., Ceredig R., Cerottini J.C., Louis J.A. Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice. J. Immunol. 135:1985.
    • (1985) J. Immunol. , vol.135
    • Titus, R.G.1    Ceredig, R.2    Cerottini, J.C.3    Louis, J.A.4
  • 35
    • 0025085508 scopus 로고
    • Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen
    • Newell M.K., Haughn L.J., Maroun C.R., Julius M.H. Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen. Nature. 347:1990;286-289.
    • (1990) Nature , vol.347 , pp. 286-289
    • Newell, M.K.1    Haughn, L.J.2    Maroun, C.R.3    Julius, M.H.4
  • 36
    • 0026757808 scopus 로고
    • In vivo and in vitro death of mature T cells induced by separate signals to CD4 and alpha beta TCR
    • Facchinetti A., Panozzo M., Pertile P., Tessarollo L., Biasi G. In vivo and in vitro death of mature T cells induced by separate signals to CD4 and alpha beta TCR. Immunobiology. 185:1992;380-389.
    • (1992) Immunobiology , vol.185 , pp. 380-389
    • Facchinetti, A.1    Panozzo, M.2    Pertile, P.3    Tessarollo, L.4    Biasi, G.5
  • 37
    • 0026561078 scopus 로고
    • Activated type II collagen reactive T cells are not eliminated by in vivo anti-CD4 treatment: Implications for therapeutic approaches on autoimmune arthritis
    • Goldschmidt T.J., Andersson M., Malmstrom V., Holmdahl R. Activated type II collagen reactive T cells are not eliminated by in vivo anti-CD4 treatment: implications for therapeutic approaches on autoimmune arthritis. Immunobiology. 184:1992;359-371.
    • (1992) Immunobiology , vol.184 , pp. 359-371
    • Goldschmidt, T.J.1    Andersson, M.2    Malmstrom, V.3    Holmdahl, R.4
  • 38
    • 0027281563 scopus 로고
    • The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory
    • Akbar A.N., Borthwick N., Salmon M., Gombert W., Bofill M., Shamsadeen N., Pilling D., Pett S., Grundy J.E., Janossy G. The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory. J. Exp. Med. 178:1993;427-438.
    • (1993) J. Exp. Med. , vol.178 , pp. 427-438
    • Akbar, A.N.1    Borthwick, N.2    Salmon, M.3    Gombert, W.4    Bofill, M.5    Shamsadeen, N.6    Pilling, D.7    Pett, S.8    Grundy, J.E.9    Janossy, G.10
  • 39
    • 0025516520 scopus 로고
    • The antiglobulin response to therapeutic antibodies
    • Isaacs J.D. The antiglobulin response to therapeutic antibodies. Sem. Immunol. 2:1990;449-456.
    • (1990) Sem. Immunol. , vol.2 , pp. 449-456
    • Isaacs, J.D.1
  • 40
    • 0030058669 scopus 로고    scopus 로고
    • CD4-imitating human antibodies in HIV infection and anti-idiotypic vaccination
    • Deckert P.M., Ballmaier M., Lang S., Deicher H., Schedel I. CD4-imitating human antibodies in HIV infection and anti-idiotypic vaccination. J. Immunol. 156:1996;826-833.
    • (1996) J. Immunol. , vol.156 , pp. 826-833
    • Deckert, P.M.1    Ballmaier, M.2    Lang, S.3    Deicher, H.4    Schedel, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.