메뉴 건너뛰기




Volumn 25, Issue 1, 1997, Pages 68-78

Estimating relative potency for receptor-mediated toxicity: Reevaluating the toxicity equivalence factor (TEF) model

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ENVIRONMENTAL CHEMICAL; POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN; RECEPTOR;

EID: 0031079625     PISSN: 02732300     EISSN: None     Source Type: Journal    
DOI: 10.1006/rtph.1996.1063     Document Type: Article
Times cited : (46)

References (45)
  • 4
    • 0029564557 scopus 로고
    • Mechanisms for species differences in receptor-mediated carcinogenesis
    • Barrett, J. C. (1995). Mechanisms for species differences in receptor-mediated carcinogenesis. Mutat. Res. 333, 189-202.
    • (1995) Mutat. Res. , vol.333 , pp. 189-202
    • Barrett, J.C.1
  • 5
    • 0029591584 scopus 로고
    • Use of toxic equivalency factors for risk assessment for dioxins and related compounds
    • Birnbaum, L. S., and DeVito, M. J. (1995). Use of toxic equivalency factors for risk assessment for dioxins and related compounds. Toxicology 105, 391-402.
    • (1995) Toxicology , vol.105 , pp. 391-402
    • Birnbaum, L.S.1    DeVito, M.J.2
  • 6
    • 0023635937 scopus 로고
    • Teratogenic effects of polychlorinated dibenzofurans in combination in C57BL/6N mice
    • Birnbaum, L. S., Harris, M. W., Crawford, D. D., and Morrissey, R. E. (1987). Teratogenic effects of polychlorinated dibenzofurans in combination in C57BL/6N mice. Toxicol. Appl. Pharmacol. 91, 246-255.
    • (1987) Toxicol. Appl. Pharmacol. , vol.91 , pp. 246-255
    • Birnbaum, L.S.1    Harris, M.W.2    Crawford, D.D.3    Morrissey, R.E.4
  • 7
    • 0024242449 scopus 로고
    • A competitive binding assay for 2,3,7,8-tetrachlorodibenzo-p-dioxin and related ligands of the ah receptor
    • Bradfield, C. A., and Poland, A. (1988). A competitive binding assay for 2,3,7,8-tetrachlorodibenzo-p-dioxin and related ligands of the Ah receptor. Mol. Pharmacol. 34, 682-688.
    • (1988) Mol. Pharmacol. , vol.34 , pp. 682-688
    • Bradfield, C.A.1    Poland, A.2
  • 8
    • 0011220526 scopus 로고
    • Risk assessment of mixtures: A model based on mechanisms of action and interaction
    • (C. Zervos, K. Knox, L. Abramson, and R. Coppock, Eds.), Plenum Press, NY
    • Clevenger, M. A., Putzrath, R. M., Ginevan, M. E., Brown, S. L., De-Rosa, C. M., and Muntaz, M. M. (1991). Risk assessment of mixtures: A model based on mechanisms of action and interaction. In Risk Analysis: Prospects and Opportunities (C. Zervos, K. Knox, L. Abramson, and R. Coppock, Eds.), pp. 293-303. Plenum Press, NY.
    • (1991) Risk Analysis: Prospects and Opportunities , pp. 293-303
    • Clevenger, M.A.1    Putzrath, R.M.2    Ginevan, M.E.3    Brown, S.L.4    De-Rosa, C.M.5    Muntaz, M.M.6
  • 9
    • 77957180789 scopus 로고
    • A new method for determining allowable daily intakes
    • Crump, K. S. (1984). A new method for determining allowable daily intakes. Fundam. Appl. Toxicol. 4, 854-871.
    • (1984) Fundam. Appl. Toxicol. , vol.4 , pp. 854-871
    • Crump, K.S.1
  • 10
    • 77957181770 scopus 로고
    • The importance of pharmacokinetics in determining the relative potency of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran
    • DeVito, M. J., and Birnbaum, L. S. (1995). The importance of pharmacokinetics in determining the relative potency of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran. Fundam. Appl. Toxicol. 24, 145-148.
    • (1995) Fundam. Appl. Toxicol. , vol.24 , pp. 145-148
    • DeVito, M.J.1    Birnbaum, L.S.2
  • 11
    • 0028213828 scopus 로고
    • Dose-response relationships in mice following subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: CYP1A1, CYP1A2, estrogen receptor, and protein tyrosine phosphorylation
    • DeVito, M. J., Ma, X., Babish, J. G., Menache, M., and Birnbaum, L. S. (1994). Dose-response relationships in mice following subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: CYP1A1, CYP1A2, estrogen receptor, and protein tyrosine phosphorylation. Toxicol. Appl. Pharmacol. 124, 82-90.
    • (1994) Toxicol. Appl. Pharmacol. , vol.124 , pp. 82-90
    • DeVito, M.J.1    Ma, X.2    Babish, J.G.3    Menache, M.4    Birnbaum, L.S.5
  • 13
    • 0000060569 scopus 로고    scopus 로고
    • Proposed guidelines for carcinogen risk assessment
    • Environmental Protection Agency (EPA) (1996b). Proposed guidelines for carcinogen risk assessment. Fed. Reg. 61, 17960-18011.
    • (1996) Fed. Reg. , vol.61 , pp. 17960-18011
  • 14
    • 0000591956 scopus 로고
    • Proposed guidelines for neurotoxicity risk assessment
    • Notice
    • Environmental Protection Agency (EPA) (1995). Proposed guidelines for neurotoxicity risk assessment; Notice. Fed. Reg. 60, 52032-52056.
    • (1995) Fed. Reg. , vol.60 , pp. 52032-52056
  • 16
    • 0001162208 scopus 로고
    • Final guidelines for developmental toxicity risk assessment
    • Environmental Protection Agency (EPA) (1991). Final guidelines for developmental toxicity risk assessment. Fed. Reg. 56, 63798-63826.
    • (1991) Fed. Reg. , vol.56 , pp. 63798-63826
  • 18
    • 85030281708 scopus 로고
    • Final Draft. Environmental Criteria and Assessment Office. ECAO-CIN-439. May
    • Environmental Protection Agency (EPA) (1985). Health Risk Assessment Approach for 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Final Draft. Environmental Criteria and Assessment Office. ECAO-CIN-439. May.
    • (1985) Health Risk Assessment Approach for 2,3,7,8-tetrachlorodibenzo-p-dioxin
  • 19
    • 0029036955 scopus 로고
    • The search for synergy: A critical review from a response surface perspective
    • Greco, W. R., Bravo, G., and Parsons, J. C. (1995). The search for synergy: A critical review from a response surface perspective. Pharmacol. Rev. 47, 331-385.
    • (1995) Pharmacol. Rev. , vol.47 , pp. 331-385
    • Greco, W.R.1    Bravo, G.2    Parsons, J.C.3
  • 20
    • 0027983088 scopus 로고
    • New quantitative approach for analysis of binary toxic mixtures
    • Haas, C. N., and Stirling, B. A. (1994). New quantitative approach for analysis of binary toxic mixtures. Environ. Toxicol. Chem. 13, 149-156.
    • (1994) Environ. Toxicol. Chem. , vol.13 , pp. 149-156
    • Haas, C.N.1    Stirling, B.A.2
  • 21
    • 0025187956 scopus 로고
    • Structure-dependent induction of aryl hydrocarbon hydroxylase activity in C57Bl/6 mice by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related congeners: Mechanistic studies
    • Harris, M., Zacharewski, T., Piskorska-Pliszczynska, J., Rosengren, R., and Safe, S. (1990). Structure-dependent induction of aryl hydrocarbon hydroxylase activity in C57BL/6 mice by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related congeners: Mechanistic studies. Toxicol. Appl. Pharmacol. 105, 243-253.
    • (1990) Toxicol. Appl. Pharmacol. , vol.105 , pp. 243-253
    • Harris, M.1    Zacharewski, T.2    Piskorska-Pliszczynska, J.3    Rosengren, R.4    Safe, S.5
  • 23
    • 85030290484 scopus 로고
    • Toxicological interactions between 2,3,7,8-TCDD, 1,2,3,7,8-PeCDD and 2,3,4,7,8-PeCDF in rat
    • (L. Birnbaum, R. Clement, M. Fingerhut, F. Matsumura, S. Ramamoorthy, L. Robertson, and S. Safe, Eds.), DIOXIN '95 Secretariat, P.O. Box 46060, Edmonton, Canada
    • Johansson, N., Waern, F., Trossvik, C., Manzoor, E., Ahlborg, U. G., and Håkasson, H. (1995). Toxicological interactions between 2,3,7,8-TCDD, 1,2,3,7,8-PeCDD and 2,3,4,7,8-PeCDF in rat. In Organohalogen Compounds (L. Birnbaum, R. Clement, M. Fingerhut, F. Matsumura, S. Ramamoorthy, L. Robertson, and S. Safe, Eds.), Vol. 25, pp. 7-14. DIOXIN '95 Secretariat, P.O. Box 46060, Edmonton, Canada.
    • (1995) Organohalogen Compounds , vol.25 , pp. 7-14
    • Johansson, N.1    Waern, F.2    Trossvik, C.3    Manzoor, E.4    Ahlborg, U.G.5    Håkasson, H.6
  • 24
    • 0027495175 scopus 로고
    • Effects of the mechanism of receptor-mediated gene expression on the shape of the dose-response curve
    • Kohn, M. C., and Portier, C. (1993). Effects of the mechanism of receptor-mediated gene expression on the shape of the dose-response curve. Risk Anal. 13, 565-572.
    • (1993) Risk Anal. , vol.13 , pp. 565-572
    • Kohn, M.C.1    Portier, C.2
  • 25
    • 0029025454 scopus 로고
    • Extended concentration-response curves used to reflect full agonist efficacies and receptor occupancy-response coupling ranges
    • Lew, M. J. (1995). Extended concentration-response curves used to reflect full agonist efficacies and receptor occupancy-response coupling ranges. Br. J. Pharmacol. 115, 745-752.
    • (1995) Br. J. Pharmacol. , vol.115 , pp. 745-752
    • Lew, M.J.1
  • 26
    • 0027744290 scopus 로고
    • Dose response for TCDD promotion of hepatocarcinogenesis in rats initiated with DEN: Histologic, biochemical, and cell proliferation endpoints
    • Maronpot, R. R., Foley, J. F., Takahashi, K., Goldsworthy, T., Clark, G., Tritscher, A., Portier, C., and Lucier, G. (1993). Dose response for TCDD promotion of hepatocarcinogenesis in rats initiated with DEN: Histologic, biochemical, and cell proliferation endpoints. Environ. Health Perspect. 101, 634-642.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 634-642
    • Maronpot, R.R.1    Foley, J.F.2    Takahashi, K.3    Goldsworthy, T.4    Clark, G.5    Tritscher, A.6    Portier, C.7    Lucier, G.8
  • 27
    • 0029070412 scopus 로고
    • Alternative models for low dose-response analysis of biochemical and immunological endpoints for tetrachlorodibenzo-p-dioxin
    • McGrath, L. F., Cooper, K. R., Georgopoulos, P., and Gallo, M. (1995). Alternative models for low dose-response analysis of biochemical and immunological endpoints for tetrachlorodibenzo-p-dioxin. Reg. Toxicol. Pharmacol. 21, 382-396.
    • (1995) Reg. Toxicol. Pharmacol. , vol.21 , pp. 382-396
    • McGrath, L.F.1    Cooper, K.R.2    Georgopoulos, P.3    Gallo, M.4
  • 28
    • 0028061161 scopus 로고
    • Toxic responses to defined chemical mixtures: Mathematical models and experimental designs
    • Michaud, J. P., Gandolfi, A. J., and Brendel, K. (1994). Toxic responses to defined chemical mixtures: Mathematical models and experimental designs. Life Sci. 55, 635-651.
    • (1994) Life Sci. , vol.55 , pp. 635-651
    • Michaud, J.P.1    Gandolfi, A.J.2    Brendel, K.3
  • 30
    • 0029002098 scopus 로고
    • Relative potency of polychlorinated dibenzo-p-dioxins and dibenzofurans for inducing mixed-function oxygenases activity in rainbow trout
    • Parrott, J. L., Hodson, P. V., and Servos, M. R. (1995). Relative potency of polychlorinated dibenzo-p-dioxins and dibenzofurans for inducing mixed-function oxygenases activity in rainbow trout. Environ. Toxicol. Chem. 14, 1041-1050.
    • (1995) Environ. Toxicol. Chem. , vol.14 , pp. 1041-1050
    • Parrott, J.L.1    Hodson, P.V.2    Servos, M.R.3
  • 31
    • 0011160739 scopus 로고
    • Improving toxic equivalence factors (TEFs) for PCBs
    • Hazardous Materials Control Resources Institute, Rockville, MD
    • Putzrath, R. M., and Ginevan, M. E. (1994). Improving toxic equivalence factors (TEFs) for PCBs. In Superfund XV Conference Proceedings, Vol. 2, pp. 1457-1463. Hazardous Materials Control Resources Institute, Rockville, MD.
    • (1994) Superfund XV Conference Proceedings , vol.2 , pp. 1457-1463
    • Putzrath, R.M.1    Ginevan, M.E.2
  • 32
    • 0028962708 scopus 로고
    • A novel application of a competitive binding model in dioxin risk assessment
    • Rao, V. R., and Unger, A. (1995). A novel application of a competitive binding model in dioxin risk assessment. Reg. Toxicol. Pharmacol. 21, 108-116.
    • (1995) Reg. Toxicol. Pharmacol. , vol.21 , pp. 108-116
    • Rao, V.R.1    Unger, A.2
  • 33
    • 0026674145 scopus 로고
    • Kinetics of the association of several tritiated polychlorinated dibenzo-p-dioxin and dibenzofuran congeners with hepatic cytosolic Ah receptor from the Wistar rat
    • Rosengren, R., Safe, S., and Bunce, N. J. (1992). Kinetics of the association of several tritiated polychlorinated dibenzo-p-dioxin and dibenzofuran congeners with hepatic cytosolic Ah receptor from the Wistar rat. Chem. Res. Toxicol. 5, 376-382.
    • (1992) Chem. Res. Toxicol. , vol.5 , pp. 376-382
    • Rosengren, R.1    Safe, S.2    Bunce, N.J.3
  • 34
    • 0024997614 scopus 로고
    • Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs)
    • Safe, S. (1990). Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). CRC Crit. Rev. Toxicol 21, 51-88.
    • (1990) CRC Crit. Rev. Toxicol , vol.21 , pp. 51-88
    • Safe, S.1
  • 35
    • 21844489673 scopus 로고
    • Threshold models for combination data from reproductive and developmental experiments
    • Schwartz, P. F., Gennings, C., and Chinchilli, V. M. (1995). Threshold models for combination data from reproductive and developmental experiments. J. Am. Stat. Assoc. 90, 862-870.
    • (1995) J. Am. Stat. Assoc. , vol.90 , pp. 862-870
    • Schwartz, P.F.1    Gennings, C.2    Chinchilli, V.M.3
  • 36
    • 77957179884 scopus 로고
    • Evaluation of the interaction of three genotoxic agents in eliciting sister-chromatid exchanges using response surface methodology
    • Solana, R. P., Chinchilli, V. M., Wilson, J. D., Carter, W. H., Jr., and Carchman, R. A. (1987). Evaluation of the interaction of three genotoxic agents in eliciting sister-chromatid exchanges using response surface methodology. Fundam. Appl. Toxicol. 9, 541-549.
    • (1987) Fundam. Appl. Toxicol. , vol.9 , pp. 541-549
    • Solana, R.P.1    Chinchilli, V.M.2    Wilson, J.D.3    Carter W.H., Jr.4    Carchman, R.A.5
  • 37
    • 0010673662 scopus 로고
    • A modification of receptor theory
    • Stephenson, R. P. (1956). A modification of receptor theory. Br. J. Pharmacol. 11, 379-393.
    • (1956) Br. J. Pharmacol. , vol.11 , pp. 379-393
    • Stephenson, R.P.1
  • 38
    • 0001132203 scopus 로고
    • Statistical methods for the toxicological evaluation of the additivity assumption as used in the Environmental Protection Agency Chemical Mixture Risk Assessment Guidelines
    • (R. S. H. Yang, Ed.), Academic Press, New York
    • Svendsgaard, D. J., and Hertzberg, R. C. (1995). Statistical methods for the toxicological evaluation of the additivity assumption as used in the Environmental Protection Agency Chemical Mixture Risk Assessment Guidelines. In Toxicology of Chemical Mixtures (R. S. H. Yang, Ed.), pp. 599-642. Academic Press, New York.
    • (1995) Toxicology of Chemical Mixtures , pp. 599-642
    • Svendsgaard, D.J.1    Hertzberg, R.C.2
  • 39
    • 0029160204 scopus 로고
    • Receptor discrimination and control of agonist-antagonist binding
    • Tallarida, R. J. (1995). Receptor discrimination and control of agonist-antagonist binding. Am. J. Physiol. 269, E379-E391.
    • (1995) Am. J. Physiol. , vol.269
    • Tallarida, R.J.1
  • 41
    • 0002163185 scopus 로고
    • Molecular basis of pharmacologic selectivity
    • (W. B. Pratt and P. Taylor, Eds.), 3rd ed. Churchill Livingstone, NY
    • Taylor, P., and Insel, P. A. (1990). Molecular basis of pharmacologic selectivity. In Principles of Drug Action (W. B. Pratt and P. Taylor, Eds.), 3rd ed. Churchill Livingstone, NY.
    • (1990) Principles of Drug Action
    • Taylor, P.1    Insel, P.A.2
  • 42
    • 26844508946 scopus 로고    scopus 로고
    • Potency of a complex mixture of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin in causing fish early life stage mortality
    • Walker, M. K., Cook, P. M., Butterworth, B. C., Zabel, E. W., and Peterson, R. E. (1996). Potency of a complex mixture of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin in causing fish early life stage mortality. Fundam. Appl. Toxicol. 30, 178-186.
    • (1996) Fundam. Appl. Toxicol. , vol.30 , pp. 178-186
    • Walker, M.K.1    Cook, P.M.2    Butterworth, B.C.3    Zabel, E.W.4    Peterson, R.E.5
  • 43
    • 0011160740 scopus 로고
    • Drug-receptor interactions
    • (Z. M. Bacq, R. Čapek, R. Paoletti, and J. Renson, Eds.), Pergamon Press, New York
    • Wenke, M. (1971). Drug-receptor interactions. In Fundamentals of Biochemical Pharmacology (Z. M. Bacq, R. Čapek, R. Paoletti, and J. Renson, Eds.), pp. 367-410. Pergamon Press, New York.
    • (1971) Fundamentals of Biochemical Pharmacology , pp. 367-410
    • Wenke, M.1
  • 44
    • 0028871605 scopus 로고
    • Interactions of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners for producing rainbow trout early life stage mortality
    • Zabel, E. W., Walker, M. K., Hornung, M. W., Clayton, M. K., and Peterson, R. E. (1995). Interactions of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners for producing rainbow trout early life stage mortality. Toxicol. Appl. Pharmacol. 134, 204-213.
    • (1995) Toxicol. Appl. Pharmacol. , vol.134 , pp. 204-213
    • Zabel, E.W.1    Walker, M.K.2    Hornung, M.W.3    Clayton, M.K.4    Peterson, R.E.5
  • 45
    • 0024346536 scopus 로고
    • Induction of cytochrome P450-dependent monoxygenase activities in rat hepatoma H-4-IIE cells in culture by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds: Mechanistic studies using radiolabeled congeners
    • Zacharewski, T., Harris, M., and Safe, S. (1989). Induction of cytochrome P450-dependent monoxygenase activities in rat hepatoma H-4-IIE cells in culture by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds: Mechanistic studies using radiolabeled congeners. Arch. Biochem. Biophys. 272, 344-355.
    • (1989) Arch. Biochem. Biophys. , vol.272 , pp. 344-355
    • Zacharewski, T.1    Harris, M.2    Safe, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.