Potency of a complex mixture of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin in causing fish early life stage mortality

Fundamental and Applied Toxicology

Volumn 30, Issue 2, 1996, Pages 178-186

  Walker, Mary K ^a   Cook, Philip M ^b   Butterworth, Brian C ^b   Zabel, Erik W ^a   Peterson, Richard E ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; POLYCHLORINATED BIPHENYL; POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; EGG; FISH; LD 50; MORTALITY; NONHUMAN; RAINBOW TROUT; TOXICITY; TROUT;

EID: 26844508946     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1996.0054     Document Type: Article

References (37)

1. Abbott, W. S. (1925). A method of computing the effectiveness of an insecticide. J. Econ. Entomol. 18, 265-267.
2. Ballschmiter, K., and Zell, M. (1980). Analysis of polychlorinated biphenyls by capillary gas chromatography. Fresenius J. Anal. Chem. 302, 20-31.
3. Bartlett, G. R. (1959). Phosphorus assay in column chromatography. J. Biol. Chem. 234, 466-468.
4. Bellin, J. S., and Barnes, D. G. (1989). Interim Procedures for Estimating Risks Associated with Exposure to Mixtures of Chlorinated Dibenzo-p-dioxins and-Dibenzofurans (CDDs and CDFs), EPA/625/3-89/016. U.S. Environmental Protection Agency, Washington, DC.
5. Biegel, L., Harris, M., Davis, D., Rosengren, R., Safe, L., and Safe, S. (1989). 2,2′,4,4′,5,5′-Hexachlorobiphenyl as 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice. Toxicol Appl. Pharmacol 97, 561-571.
6. Bol, J., Van den Berg, M., and Seinen, W. (1989). Interactive effects of PCDD's, PCDF's, and PCB's as assessed by the E.L.S.-bioassay. Chemosphere 19, 899-906.
7. Brown, M. M., Schneider, U. A., Petrulis, J. R., and Bunce, N. J. (1994). Additive binding of polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to the murine hepatic Ah receptor. Toxicol. Appl. Pharmacol. 129, 243-251.
8. Cook, P. M., Walker, M. K., Kuehl, D. W., and Peterson, R. E. (1991). Bioaccumulation and toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds in aquatic ecosystems. In Biological Basis for Risk Assessment of Dioxins and Related Compounds (M. A. Gallo, R. J. Scheuplein, and C. A. vander Heijden, Eds.), Banbury Report, Vol. 35, pp. 143-167. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
9. Cook, P. M., Butterworth, B. C., Walker, M. K., Hornung, M. W., Zabel, E. W., and Peterson, R. E. (1994). Lake trout recruitment in the Great Lakes: relative risks for chemical-induced early life stage mortality. Soc. Environ. Toxicol. Chem. Abstracts 15: 58.
10. Eadon, G., Kaminsky, L., Silkworth, J., Aldous, K., Hilker, D., O'Keefe, P., Smith, R., Gierthy, J., Hawley, J., Kim, N., and DeCapno, A. (1986). Calculation of 2,3,7,8-TCDD equivalent concentrations of complex environmental contaminant mixtures. Environ. Health Perspect. 70, 221-227.
11. EPA (Environmental Protection Agency) (1991). Bioaccumulation of Selected Pollutants in Fish, EPA 506/6-90/001b. USEPA, Office of Water Regulations and Standards, Washington, DC.
12. EPA (Environmental Protection Agency) (1993). Interim Report on Data and Methods for Assessment of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Risks to Aquatic Life and Associated Wildlife, EPA/600/R-93/005.
13. Finney, D. J. (1971). Probit Analysis, 3rd ed. Cambridge Univ. Press, Cambridge.
14. Haake, J. M., Safe, S., Mayura, K., and Phillips, T. D. (1987). Aroclor 1254 as an antagonist of the teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Lett. 31, 151-158.
15. Janz, D. M., and Metcalfe, C. D. (1991). Nonadditive interactions of mixture of 2,3,7,8-TCDD and 3,3′,4,4′-tetrachlorobiphenyl on aryl hydrocarbon hydroxylase induction in rainbow trout (Oncorhynchus mykiss). Chemosphere 23, 467-472.
16. Kuehl, D. W., Butterworth, B. C., Libal, J. J., and Marquis, P. (1991). An isotope dilution high resolution gas chromatographic-high resolution mass spectrometric method for the determination of coplanar polychlorinated biphenyls: Application to fish and marine mammals. Chemosphere 22, 849-858.
17. Mac, M., Schwartz, T. R., Edsall, C. C., and Frank, A. M. (1993). Polychlorinated biphenyls in Great Lakes lake trout and their eggs: Relations to survival and congener composition. Int. J. Great Lakes Res. 19, 752-765.
18. Miller, M. A. (1993). Maternal transfer of lipophilic contaminants in Salmonines to their eggs. Can. J. Fish. Aquat. Sci. 49, 1405-1413.
19. Olson, J. R. (1986). Metabolism and disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin in guinea pigs. Toxicol. Appl. Pharmacol. 85, 263-273.
20. Poland, A., and Knutson, J. C. (1982). 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22, 517-524.
21. Poland, A., Glover, E., and Kende, A. S. (1976). Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. J. Biol Chem. 251, 4936-4946.
22. Safe, S. (1990). Polychlonnated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit. Rev. Toxicol. 21, 51-88.
23. Safe, S. (1994). Polychlorinated biphenyls (PCBs): Environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit. Rev. Toxicol. 24, 87-149.
24. R Technical Report P-179, Additional SAS/ STAT™ Procedures, Release 6.03, Cary, NC.
25. Shain, W., Bush, B., and Seegal, R. F. (1991). Neurotoxicity of polychlorinated biphenyls: Structure-activity relationships of individual congeners. Toxicol. Appl. Pharmacol. 111, 33-42.
26. Smith, L. M., Schwartz, T. R., Feltz, K., and Kubiak, T. J. (1990). Determination and occurrence of AHH-active polychlorinated biphenyls, 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran in Lake Michigan sediment and biota. The question of their relative toxicological significance. Chemosphere 21, 1063-1085.
27. Spitsbergen, J. M., Walker, M. K., Olson, J. R., and Peterson, R. E. (1991). Pathologic alterations in early life stages of lake trout, Salvelinus namaycush, exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin as fertilized eggs. Aquat. Toxicol. 19, 41-72.
28. Walker, M. K., and Peterson, R. E. (1991). Potencies of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners, relative to 2,3,7,8-tetrachlorodibenzo-p-dioxin, for producing early life stage mortality in rainbow trout. Aquat. Toxicol. 21, 219-238.
29. Walker, M. K., and Peterson, R. E. (1994). Aquatic toxicity of dioxins and related chemicals. In Dioxins and Health (A. Schecter, Ed.), pp. 347-387. Plenum, New York.
30. Walker, M. K., Spitsbergen, J. M., Olson, J. R., and Peterson, R. E. (1991). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) toxicity during early life stage development of lake trout (Salvelinus namaycush). Can. J. Fish. Aquat. Sci. 48, 875-883.
31. Walker, M. K., Hufnagle, Jr., L. C., Clayton, M. K., and Peterson, R. E. (1992). An egg injection method for assessing early life stage mortality of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 22, 15-38.
32. Walker, M. K., Cook, P. M., Batterman, A., Butterworth, B., Bernini, C., Libal, J. J., Hufnagle, Jr., L. C., and Peterson, R. E. (1994). Translocation of 2,3,7,8-tetrachlorodibenzo-p-dioxin from adult female lake trout (Salvelinus namaycush) to oocytes: Effects on early life stage development and sac fry survival. Can. J. Fish. Aquat. Sci. 51, 1410-1419.
33. Walker, M. K., Zabel, E. W., Åkerman, G., Balk, L., Wilson, P., and Tillitt, D. E. (1996). Fish egg injection as an exposure route for early life stage toxicity studies. In Techniques in Aquatic Toxicology (G. Ostrander, Ed.), in press. Lewis Publishers/CRC Press, Boca Raton, FL.
34. Wisk, J. D., and Cooper, K. R. (1990). Comparison of the toxicity of several polychlorinated dibenzo-p-dioxins and 2,3,7,8-tetrachlorodibenzofuran in embryos of the Japanese medaka (Oryzias latipes). Chemosphere 20, 361-377 (1990).
35. Wonnacott, R. J., and Wonnacott, T. H. (1985). Introductory Statistics, 4th ed. Wiley, New York.
36. Zabel, E. W., Cook, P. M., and Peterson, R. E. (1995a). Toxic equivalency factors of polychlorinated dibenzo-p-dioxin, dibenzofuran and biphenyl congeners based on early life stage mortality in rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 31, 315-328.
37. Zabel, E. W., Walker, M. K., Hornung, M. W., Clayton, M. K., and Peterson, R. E. (1995b). Interactions of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners for producing rainbow trout early life stage mortality. Toxicol. Appl. Pharmacol. 134, 204-213.