The genetic analysis of prostate carcinoma

Seminars in Cancer Biology

Volumn 8, Issue 1, 1997, Pages 37-44

  Roylance, Rebecca ^b   Spurr, Nigel ^a   Sheer, Denise ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Comparative genomic hybridization; Cytogenetics; Fluorescence in situ hybridization; Loss of heterozygosity; Prostate cancer

Indexed keywords

ANDROGEN RECEPTOR;

CANCER GENETICS; CANCER HORMONE THERAPY; CANCER RESISTANCE; CARCINOGENESIS; CHROMOSOME 10; CHROMOSOME 13Q; CHROMOSOME 16Q; CHROMOSOME 17P; CHROMOSOME 17Q; CHROMOSOME 5Q; CHROMOSOME 7; CHROMOSOME 8P; CHROMOSOME 8Q; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME LOSS; CHROMOSOME NUMBER; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENETIC DISORDER; GENOME; HETEROZYGOSITY LOSS; HUMAN; MALE; METASTASIS; MOLECULAR GENETICS; PROSTATE CANCER; REVIEW; TRISOMY 8; Y CHROMOSOME;

EID: 0031079377     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1006/scbi.1997.0051     Document Type: Article

References (65)

1. 1. Fearon ER, Vogelstein B (1990) A genetic model for colorectal tumorigenesis. Cell 61:759-767
2. 2. Smith JR, Freije D, Carpten JD, Gronberg H, Xu J, Isaacs SD, Brownstein MJ, Bova GS, Guo H, Bujnovszky P, Nusskern DR, Damber JE, Bergh A, Emanuelsson M, Kallioniemi OP, Walker-Daniels J, Bailey-Wilson JE, Beaty TH, Meyers DA, Walsh PC, Collins FS, Trent JM, Isaacs WB (1996) Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome wide search. Science 274:1371-1374
3. 3. Gittes RF (1991) Carcinoma of the prostate. N Engl J Med 324:236-245
4. 4. Arps S, Rodewald A, Schmalenberger B, Carl P, Bressel M, Kastendieck H (1993) Cytogenetic survey of 32 cancers of the prostate. Cancer Genet Cytogenet 66:93-99
5. 5. Atkin NB, Baker MC (1985) Chromosome study of five cancers of the prostate. Hum Genet 70:359-364
6. 6. Brothman AR, Peehl DM, Patel AM, MacDonald GR, McNeal JE, Ladaga LE, Schellhammer PF (1991) Cytogenetic evaluation of 20 cultured primary prostatic tumours. Cancer Genet Cytogenet 55:79-84
7. 7. Lundgren R, Mandahl N, Heim S, Limon J, Henrikson H, Mitelman F (1992) Cytogenetic analysis of 57 primary prostatic adenocarcinomas. Genes Chromosomes Cancer 4:16-24
8. 8. Micale MA, Sanford JS, Powell IJ, Sakr WA, Wolman SR (1993) Defining the extent and nature of Cytogenetic events in prostatic adenocarcinoma: paraffin FISH vs. metaphase analysis. Cancer Genet Cytogenet 69:7-12
9. 9. Milasin J, Micic S (1994) Double minute chromosomes in an invasive adenocarcinoma of the prostate. Cancer Genet Cytogenet 72:157-159
10. 10. Qi H, Dal-Cin P, Van de Voorde W, Elgamal AA, Van Poppel H, Baert L, Van den Berghe H (1996) del(1)(q12) in adenocarcinomas of the prostate. Cancer Genet Cytogenet 87:79-81
11. 11. Webb HD, Hawkins AL, Griffin CA (1996) Cytogenetic abnormalities are frequent in uncultured prostate cancer cells. Cancer Genet Cytogenet 88:126-132
12. 12. Zitzelsberger H, Szucs S, Robens E, Weier HU, Hofler H, Bauchinger M (1996) Combined Cytogenetic and molecular genetic analyses of fifty-nine untreated human prostate carcinomas. Cancer Genet Cytogenet 90:37-44
13. 13. Ware JL (1994) Prostate cancer progression. Implications of histopathology. Am J Pathol 145:983-993
14. 14. Pandis N, Bardi G, Heim S (1994) Interrelationship between methodological choices and conceptual models in solid tumor cytogenetics. Cancer Genet Cytogenet 76:77-84
15. 15. Ketter R, Zwergel T, Romanakis K, Unteregger G, Ziegler M, Zang KD, Wullich B (1996) Selection toward diploid cells in prostatic carcinoma derived cell cultures. Prostate 28:364-371
16. 16. Konig JJ, Teubel W, van Dongen JW, Hagemeijer A, Romijn JC, Schroder FH (1993) Tissue culture loss of aneuploid cells from carcinomas of the prostate. Genes Chromosome Cancer 8:22-27
17. 17. Qian J, Bostwick DG, Takahashi S, Borell TJ, Brown JA, Lieber MM, Jenkins RB (1996) Comparison of fluorescence in situ hybridization analysis of isolated nuclei and routine histological sections from paraffin-embedded prostatic adenocarcinoma specimens. Am J Pathol 149:1193-1199
18. 18. Kallioniemi A, Kallioniemi O-P, Sudar D, Rutovitz D, Gray JW, Waldman F, Pinkel D (1992) Comparative genomic hybridization for molecular cytogenetic analysis of solid tumours. Science 258:818-821
19. 19. Kallioniemi O-P, Kallioniemi A, Piper J, Isola J, Waldman FM, Gray JW, Pinkel D (1994) Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors. Genes Chromosomes Cancer 10:231-243
20. 20. Cher ML, MacGrogan D, Bookstein R, Brown JA, Jenkins RB, Jensen RH (1994) Comparative genomic hybridization, allelic imbalance, and fluorescence in situ hybridization on chromosome 8 in prostate cancer. Genes Chromosomes Cancer 11:153-162
21. 21. Cher ML, Bova GS, Moore DH, Small EJ, Carroll PR, Pin SS, Epstein JI, Isaacs WB, Jensen RH (1996) Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping. Cancer Res 56:3091-3102
22. 22. Joos S, Bergerheim USR, Pan Y, Matsuyama H, Bentz M, du Manoir S, Lichter P (1995) Mapping of chromosomal gains and losses in prostate cancer by comparative genomic hybridization. Genes Chromosomes Cancer 14:267-276
23. 23. Visakorpi T, Kallioniemi A, Syvanen A-C, Hyytinen ER, Karhu R, Tammela T, Isola JJ, Kallioniemi O-P (1995) Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization. Cancer Res 55:342-347
24. 24. Visakorpi T, Hyytinen E, Koivisto P, Tanner M, Keinanen R, Palmberg C, Palotie A, Tammela T, Isola J, Kallioniemi O-P (1995) In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat Genet 9:401-406
25. 25. Mitelman F (ed.) (1994) Catalog of chromosome aberrations in cancer, vol 1. Wiley-Liss Inc, New York
26. 26. Inazawa J, Sasaki H, Nagura K, Kakazu N, Abe T, Sasaki T (1996) Precise localization of the human gene encoding cell adhesion kinase β (CAKβ/ PYK2) to chromosome 8 at p21.1 by fluorescence in situ hybridization. Hum Genet 98:508-510
27. 27. Huang SF, Xiao S, Renshaw AA, Loughlin KR, Hudson TJ, Fletcher JA (1996) Fluorescence in situ hybridization evaluation of chromosome deletion patterns in prostate cancer. Am J Pathol 149:1565-1573
28. 28. Macoska JA, Micale MA, Sakr WA, Benson PD, Wolman SR (1993) Extensive genetic alterations in prostate cancer revealed by dual PCR and FISH analysis. Genes Chromosomes Cancer 8:88-97
29. 29. Macoska JA, Trybus TM, Sakr WA, Wolf MC, Benson PD, Powell IJ, Pontes JE (1994) Fluorescence in situ hybridization analysis of 8p allelic loss and chromosome 8 instability in human prostate cancer. Cancer Res 54:3824-3830
30. 30. Matsuyama H, Pan Y, Skoog L, Tribukait B, Naito K, Ekman P, Lichter P, Bergerheim USR (1994) Deletion mapping of chromosome 8p in prostate cancer by fluorescence in situ hybridization. Oncogene 9:3071-3076
31. 31. MacGrogan D, Levy A, Bostwick D, Wagner M, Wells D, Bookstein R (1994) Loss of chromosome arm 8p loci in prostate cancer: mapping by quantitative allelic imbalance. Genes Chromosomes Cancer 10:151-159
32. 32. Vocke CD, Pozzatti RO, Bostwick DG, Florence CD, Jennings SB, Strup SE, Duray PH, Liotta LA, Emmert-Buck MR, Linehan WM (1996) Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21. Cancer Res 56:2411-2416
33. 33. Emmert-Buck M, Vocke C, Pozzatti R, Duray P, Jennings S, Florence C, Zhuang Z, Bostwick D, Liotta L, Linehan W (1995) Allelic loss on chromosome 8p12-21 in microdissected prostatic intraepithelial neoplasia. Cancer Res 55:2959-2962
34. 34. Mertens F, Johansson B, Mitelman F (1994) Isochromosomes in neoplasia. Genes Chromosomes Cancer 10:221-230
35. 35. Van den Berg C, Guan X-Y, Von Hoff D, Jenkins R, Bittner M, Griffin C, Kallioniemi O, Visakorpi T, McGill J, Herath J, Epstein J, Sarosdy M, Meltzer P, Trent J (1995) DNA sequence amplification in human prostate cancer identified by chromosome microdissection: Potential prognostic implications. Clin Cancer Res 1:11-18
36. 36. Jenkins RB, Qian JQ, Lieber MM, Bostwick DG (1997) Detection of c-myc oncogene amplification and chromosomal-anomalies in metastatic prostatic-carcinoma by fluorescence in-situ hybridization. Cancer Res 57:524-531
37. 37. Micale MA, Mohamed A, Sakr W, Powell IJ, Wolman SR (1992) Cytogenetics of primary prostatic adenocarcinoma. Clonality and chromosome instability. Cancer Genet Cytogenet 61:165-173
38. 38. Konig JJ, Teubel W, Romijn JC, Schroder FH, Hagemeijer A (1996) Gain and loss of chromosome 1, chromosome 7, chromosome 8, chromosome 10, chromosome 18, and chromosome Y in 46 prostate cancers. Hum Pathol 27:720-727
39. 39. Visakorpi T, Hyytinen E, Kallioniemi A, Isola J, Kallioniemi O-P (1994) Sensitive detection of chromosome copy number aberrations in prostate cancer by fluorescence in situ hybridization. Am J Pathol 145:624-630
40. 40. Qian J, Bostwick DG, Takahashi S, Borell TJ, Herath JF, Lieber MM, Jenkins RB (1995) Chromosomal anomalies in prostatic intraepithelial neoplasia and carcinoma detected by fluorescence in situ hybridization. Cancer Res 55:5408-5414
41. 41. Takahashi S, Qian J, Brown JA, Alcaraz A, Bostwick DG, Lieber MM, Jenkins RB (1994) Potential markers of prostate cancer aggressiveness detected by fluorescence in situ hybridization in needle biopsies. Cancer Res 54:3574-3579
42. 42. Matsuura H, Shiraishi T, Yatani R, Kawamura J (1996) Interphase cytogenetics of prostate cancer: fluorescence in situ hybridization (FISH) analysis of Japanese cases. Br J Cancer 74:1699-1704
43. 43. Takahashi S, Alcaraz A, Brown JA, Borell TJ, Herath JF, Bergstralh EJ, Lieber MM, Jenkins RB (1996) Aneusomies of chromosomes 8 and Y detected by fluorescence in situ hybridization are prognostic markers for pathological stage C (pT3N0M0) prostate carcinoma. Clin Cancer Res 2:137-145
44. 44. Alcaraz A, Takahashi S, Brown JA, Herath JF, Bergstralh EJ, Larson-Keller JJ, Lieber MM, Jenkins RB (1994) Aneuploidy and aneusomy of chromosome 7 detected by fluorescence in situ hybridization are markers of poor prognosis in prostate cancer. Cancer Res 54:3998-4002
45. 45. Bandyk MG, Zhao L, Troncoso P, Pisters LL, Palmer JL, von Eschenbach AC, Chung LWK, Liang JC (1994) Trisomy 7: A potential cytogenetic marker of human prostate cancer progression. Genes, Chromosomes & Cancer 9:19-27
46. 46. Jones E, Zhu XL, Rohr R, Stephenson RA, Brothman AR (1994) Aneusomy of chromosomes 7 and 17 detected by FISH in prostate cancer and the effects of selection in vitro. Genes, Chromosomes Cancer 11:163-170
47. 47. Wang RY, Troncoso P, Palmer JL, El-Naggar AK, Liang JC (1996) Trisomy 7 by dual color fluorescence in situ hybridization: a potential biological marker for prostate cancer progression. Clin Cancer Res 2:1553-1558
48. 48. Johansson B, Heim S, Mandahl N, Mertens F, Mitelman F (1993) Trisomy 7 in nonneoplastic cells. Genes Chromosomes Cancer 6:199-205
49. 49. Latil A, Cussenot O, Fournier G, Baron JC, Lidereau R (1995) Loss of heterozygosity at 7q31 is a frequent and early event in prostate cancer. Clin Cancer Res 1:1385-1389
50. 50. Cooney KA, Wetzel JC, Merajver SD, Macoska JA, Singleton TP, Wojno KJ (1996) Distinct regions of allelic loss on 13q in prostate cancer. Cancer Res 56:1142-1145
51. 51. Cher ML, Ito T, Weidner N, Carroll PR, Jensen RH (1995) Mapping of regions of physical deletion on chromosome 16q in prostate cancer cells by fluorescence in situ hybridization (FISH). J Urol 153:249-254
52. 52. Suzuki H, Komiya A, Emi M, Kuramochi H, Shiraishi T, Yatani R, Shimazaki J (1996) Three distinct commonly deleted regions of chromosome arm 16q in human primary and metastatic prostate cancers. Genes Chromosome Cancer 17:225-233
53. 53. Umbas R, Isaacs WB, Bringuier PP, Schaafsma HE, Karthaus HFM, Oosterhof GON, Debruyne FMJ, Schalken JA (1994) Decreased E-cadherin expression is associated with poor prognosis in patients with prostate cancer. Cancer Res 54:3929-3933
54. 54. Isaacs WB, Bova GS, Morton RA, Bussemakers MJG, Brooks JD, Ewing CM (1995) Molecular biology of prostate cancer progression. Cancer Surv 23:19-32
55. 55. Williams BJ, Jones E, Zhu XL, Steele MR, Stephenson RA, Rohr LR, Brothman AR (1996) Evidence for a tumor suppressor gene distal to BRCA1 in prostate cancer. J Urol 155:720-725
56. 56. Ford D, Easton DF, Bishop DT, Narod SA, Goldgar DE (1994) Risks of cancer in BRCA1 mutation carriers. Breast Cancer Linkage Consortium. Lancet 343:692-695
57. 57. Brewster SF, Browne S, Brown KW (1994) Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma. J Urol 151:1073-1077
58. 58. Trybus T, Burgess AC, Wojno KJ, Glover T, Macoska J (1996) Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer. Cancer Res 56:2263-2267
59. 59. Ittmann M (1996) Allelic loss on chromosome 10 in prostate adenocarcinoma. Cancer Res 56:2143-2147
60. 60. Gray IC, Phillips SMA, Lee SJ, Neoptolemos JP, Weissenbach J, Spurr NK (1995) Loss of the chromosomal region 10q23-25 in prostate cancer. Cancer Res 55:4800-4803
61. 61. Eagle L, Yin X, Brothman A, Williams B, Atkin N, Prochownik E (1995) Mutation of the MXI1 gene in prostate cancer. Nat Genet 9:249-255
62. 62. Jing L, Yen C, Liaw D, Podsypanina K, Bose S, Wang S, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner S, Giovanella B, Ittmann M, Tycko B, Hibshoosh H, Wigler M, Parsons R (1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275:1943-1947
63. 63. Powell I, Tyrkus M, Kleer E (1990) Apparent correlation of sex chromosome loss and disease course in urothelial cancer. Cancer Genet Cytogenet 50:97-101
64. 64. Pierre RV, Hoagland HC (1972) Age-associated aneuploidy: loss of Y chromosome from human bone marrow cells with aging. Cancer 30:889-894
65. 65. Koivisto P, Kononen J, Palmberg C, Tammela T, Hyytinen E, Isola J, Trapman J, Cleutjens K, Noordzij A, Visakorpi T, Kallioniemi O-P (1997) Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer. Cancer Res 57:314-319