Signal transduction: Splicing together the unfolded-protein response

Current Biology

Volumn 7, Issue 2, 1997, Pages

  Shamu, Caroline E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SACCHAROMYCES CEREVISIAE;

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; FUNGAL PROTEIN; HAC1 PROTEIN, S CEREVISIAE; LEUCINE ZIPPER PROTEIN; MESSENGER RNA; REPRESSOR PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSCRIPTION FACTOR;

BIOLOGICAL MODEL; BIOSYNTHESIS; CELL NUCLEUS; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; PHYSIOLOGY; PROTEIN FOLDING; REVIEW; RNA SPLICING; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL NUCLEUS; ENDOPLASMIC RETICULUM; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; LEUCINE ZIPPERS; MODELS, BIOLOGICAL; PROTEIN FOLDING; REPRESSOR PROTEINS; RNA SPLICING; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 0031068345     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(06)00038-8     Document Type: Article

References (15)

1. Shamu CE, Cox JS, Walter P: The unfolded protein response pathway in yeast. Trends Cell Biol 1994, 4:56-60.
2. Mori K, Sant A, Kohno K, Normington K, Gething MJ, Sambrook JF: A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. EMBO J 1992, 11:2583-2593.
3. Kohno K, Normington K, Sambrook J, Gething MJ, Mori K: The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum. Mol Cell Biol 1993, 13:877-890.
4. Cox JS, Shamu CE, Walter P: Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 1993, 73:1197-1206.
5. Mori K, MaW, Gething MJ, Sambrook JF: A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 1993, 74:743-756.
6. Shamu CE, Walter P: Oligomerization and phosphorylation of the Ire1 p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus. EMBO J 1996, 15:3028-3039.
7. Cox JS, Walter P: A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell 1996, 87:391-404.
8. Nojima H, Leem SH, Araki H, Sakai A, Nakashima N, Kanaoka Y, Ono Y: Hac1: A novel yeast bZIP protein binding to the CRE motif is a multicopy suppressor for cdc10 mutant of Schizosaccharomyces pombe. Nucleic Acids Res 1994, 22:5279-5288.
9. Salama SR, Hendricks KB, Thorner J: G1 cyclin degradation: the PEST motif of yeast Cln2 is necessary, but not sufficient, for rapid protein turnover. Mol Cell Biol 1994, 14:7953-7966.
10. Sidrauski C, Cox JS, Walter P: tRNA ligase is required for regulated mRNA splicing in the unfolded protein response. Cell 1996, 87:405-413.
11. Phizicky EM, Greer CL: Pre-tRNA splicing: variation on a theme or exception to the rule? Trends Biochem Sci 1993, 18:31-34.
12. Bork P, Sander C: A hybrid protein kinase-RNase in an interferon-induced pathway? FEBS Lett 1993, 334:149-152.
13. Dong B, Silverman RH: 2-5A-dependent RNase molecules dimerize during activation by 2-5A*. J Biol Chem 1995, 270:4133-4137.
14. Clark MW, Abelson J: The sub-nuclear localization of tRNA ligase in yeast. J Cell Biol 1987, 105:1515-1526.
15. Simos G, Tekotte H, Grosjean H, Segref A, Sharma K, Tollervey D, Hurt EC: Nuclear pore proteins are involved in the biogenesis of functional tRNA. EMBO J 1996, 15:2270-2284.