Synthesis of [11C]RPR-72840A and its evaluation as a radioligand for the serotonin reuptake site in positron emission tomography

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 2, 1997, Pages 397-403

  Roeda, Dirk ^a   Tavitian, Bertrand ^a   Coulon, Christine ^a   David, Frédérique ^a   Dollé, Frédéric ^a   Fuseau, Chantal ^a   Jobert, Antoinette ^a   Crouzel, Christian ^b  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

^b NONE

Author keywords

11C RPR 72840A; PET; Serotonin reuptake

Indexed keywords

CARBON 11; CITALOPRAM; RPR 72840A; SEROTONIN UPTAKE INHIBITOR; TRACER; UNCLASSIFIED DRUG; CARBON; DIAGNOSTIC AGENT; QUINAZOLINE DERIVATIVE; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BABOON; BRAIN REGION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG TISSUE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POSITRON EMISSION TOMOGRAPHY; RAT; REACTION ANALYSIS; THIN LAYER CHROMATOGRAPHY; ANIMAL; BRAIN; COMPUTER ASSISTED EMISSION TOMOGRAPHY; EVALUATION; METABOLISM; PAPIO; SCINTISCANNING; SPRAGUE DAWLEY RAT; SYNTHESIS; TISSUE DISTRIBUTION;

ANIMALS; BRAIN; CARBON RADIOISOTOPES; EVALUATION STUDIES; MALE; PAPIO; QUINAZOLINES; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SEROTONIN UPTAKE INHIBITORS; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0031066267     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(96)00256-8     Document Type: Article

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