Enhanced in vitro neurotoxicity of artemisinin derivatives in the presence of haemin

Biochemical Pharmacology

Volumn 53, Issue 1, 1997, Pages 5-10

  Smith, Sharon L ^a   Fishwick, Jeffrey ^a   McLean, W Graham ^a   Edwards, Geoffrey ^a,b   Ward, Stephen A ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

artemisinin; free radical; haem; iron; neuroblastoma; neurotoxicity

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ARTEETHER; ARTEMETHER; ARTEMISININ DERIVATIVE; BRAIN PROTEIN; CELL PROTEIN; DEOXYARTEETHER; DIHYDROARTEMISININ; FREE RADICAL; HEMIN; RADIOISOTOPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; BRAIN; CELL LINE; CELL METABOLISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; DRUG PROTEIN BINDING; MOUSE; NERVE FIBER GROWTH; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SPECTROPHOTOMETRY;

ANIMALS; ANTIMALARIALS; ARTEMISININS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; HEMIN; NEURITES; NEURONS; RATS; SESQUITERPENES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 0031060624     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00591-6     Document Type: Article

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