Adoptive transfer of murine cytomegalovirus-immune lymph node cells prevents retinitis in T-cell-depleted mice

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 2, 1997, Pages 301-310

  Lu, Yun ^a   Bigger, John E ^b   Thomas, Charles A ^b   Atherton, Sally S ^a,b  

^a Department of Cellular Biology ^*  (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

adoptive immunotherapy; BALB c mouse; immunosuppression; murine cytomegalovirus; retinitis

Indexed keywords

IMMUNOGLOBULIN G;

ADOPTIVE IMMUNOTHERAPY; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; IMMUNE DEFICIENCY; IMMUNOCOMPETENT CELL; IMMUNOGLOBULIN BLOOD LEVEL; LYMPH NODE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETINITIS; T LYMPHOCYTE; THYMECTOMY;

ANIMALS; ANTIBODIES, MONOCLONAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EYE INFECTIONS, VIRAL; FEMALE; FLOW CYTOMETRY; HERPESVIRIDAE INFECTIONS; IMMUNE TOLERANCE; IMMUNOTHERAPY, ADOPTIVE; LYMPH NODES; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED BALB C; MUROMEGALOVIRUS; OVALBUMIN; RETINITIS; T-LYMPHOCYTES; TIME FACTORS;

EID: 0031058352     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Riddell SR, Greenberg PD. Therapeutic reconstitution of human viral immunity by adoptive transfer of cytotoxic T lymphocyte clones. Curr Top Microbiol Immunol. 1994;189:9-34.
2. Rubin RH. Infection in the renal and liver transplant patient. In: Rubin RH, Young LS, eds. Clinical Approach to Infection in the Compromised Host. New York: Plenum Medical Book Co.; 1988:557-582.
3. Bloom JN, Palestine AG. The diagnosis of cytomegalovirus retinitis. Ann Intern Med. 1988;15:963-969.
4. Fay MT, Freeman WR, Wiley CA, Hardy D, Bozzette S. Atypical retinitis in patients with the acquired immunodeficiency syndrome. Am J Ophthalmol. 1988;105:483-490.
5. Jabs DA, Enger C, Bartlett JG. Cytomegalovirus retinitis and acquired immunodeficiency syndrome. Arch Ophthalmol. 1989;107:75-80.
6. Kuppermann BD, Petty JG, Richman DD, et al. Correlation between CD4 + counts and prevalence of cytomegalovirus retinitis and human immunodeficiency virus-related noninfectious retinal vasculopathy in patients with acquired immunodeficiency syndrome. Am J Ophthalmol. 1993;115:575-582.
7. Ho M, ed. Cytomegalovirus, Biology and Infection. New York: Plenum Publishing; 1982:105-129.
8. Greenberg PD, Reusser P, Goodrich JM, Riddell SR. Development of a treatment regimen for human cytomegalovirus (CMV) infection in bone marrow transplantation recipients by adoptive transfer of donor-derived CMV-specific T cell clones expanded in vitro. Ann N Y Acad Sci. 1991;636:184-195.
9. Wentworth BB, Alexander ER. Seroepidemiology of infections due to members of the herpes virus group. Am J Epidemiol. 1971;94:496-507.
10. Jacobson MA, Mills J. Serious cytomegalovirus disease in the acquired immunodeficiency syndrome (AIDS). Ann Intern Med. 1988;108:585-594.
11. Meyers JD, Flournoy N, Thomas ED. Nonbacterial pneumonia after allogeneic marrow transplantation. A review of ten years' experience. Rev Infect Dis. 1982;4:1119-1132.
12. Meyers JD, Flournoy N, Thomas ED. Risk factors for cytomegalovirus infection after human marrow transplantation. J Infect Dis. 1986;153:478-488.
13. Peterson PK, Balfour HH, Jr, Marker SC, Fryd DS, Howard RJ, Simmons RL. Cytomegalovirus disease in renal allograft recipients: A prospective study of clini cal features, risk factors and impact on renal transplantation. Medicine (Baltimore). 1980;59:283-300.
14. Heise MT, Virgin HW IV. The T-cell-independent role of gamma interferon and tumor necrosis factor alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infections. J Virol. 1995;69:904-909.
15. Ho M. Role of specific cytotoxic lymphocytes in cellular immunity against murine cytomegalovirus. Infect Immun. 1980;27:767-776.
16. Inoue Y, Minasi P, Oh JO. The role of natural killer cells in murine cytomegalovirus eye infection. Invest Ophthalmol Vis Sci. 1993;34:1954-1962.
17. Venema H, van den Berg AP, van Zanten C, van Son WJ, van der Giessen M, The TH. Natural killer cell responses in renal transplant patients with cytomegalovirus infection. J Med Virol. 1994;42:188-192.
18. Koszinowski UH, Del Val M, Reddehase MJ. Cellular and molecular basis of the protective immune response to cytomegalovirus infection. Curr Top Microbiol Immunol. 1990;154:190-220.
19. Greenberg P, Goodrich J, Riddell S. Adoptive immunotherapy of human cytomegalovirus infection: Potential role in protection from disease progression. Transplant Proc. 1991;23(Suppl):97-101.
20. Riddell SR, Reusser P, Greenberg PD. Cytotoxic T cells specific for cytomegalovirus: A potential therapy for immunocompromised patients. Rev Inject Dis. 1991;13(Suppl):S966-S973.
21. Riddell SR, Watanabe KS, Goodrich JM, Li CR, Agha ME, Greenberg PD. Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T-cell clones. Science. 1992;257:238-241.
22. Atherton SS, Newell CK, Kanter MY, Cousins SW. T cell depletion increases susceptibility to murine cytomegalovirus retinitis. Invest Ophthalmol Vis Sci. 1992;33:3353-3360.
23. Craighead JE, Martin WB, Huber SA. Role of CD4+ (helper) T cells in the pathogenesis of murine cytomegalovirus myocarditis. Lab Invest. 1992;66:755-761.
24. + lymphocyte depletion on acute murine cytomegalovirus infection. J Gen Virol. 1989;70:1765-1771.
25. Kadima-Nzuji M, Craighead JE. T-lymphocytes effect on murine cytomegalovirus pulmonary infection. Am J Pathol. 1990;137:907-912.
26. Lučin P, Pavić I, Polić B, Jonjić S, Koszinowski UH. Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands. J Virol. 1992;66:1977-1984.
27. Reddehase MJ, Mutter W, Munch K, Bühring H-J, Koszinowski UH. CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity. J Virol. 1987;61:3102-3108.
28. Shanley JD. Murine models of cytomegalovirus-associated pneumonias. Transplant Proc. 1991;23(Suppl 3):12-16.
29. Shanley JD, Pesanti EL. The relationship of viral replication to interstitial pneumonitis in murine cytomegalovirus lung infection. J Infect Dis. 1985;151:454-458.
30. Reddehase MJ, Weiland F, Münch K, Jonjić S, Lüske A, Koszinowski UH. Interstitial murine cytomegalovirus pneumonia after irradiation: Characterization of cells that limit viral replication during established infection of the lungs. J Virol. 1985;55:264-273.
31. Reddehase MJ, Jonjic S, Weiland F, Mutter W, Koszinowski UH. Adoptive immunotherapy of murine cytomegalovirus adrenalitis in the immunocompromised host: CD4-helper-independent antiviral-independent antiviral function of CD8-positive memory T lymphocytes derived from latently infected donors. J Virol. 1988;62:1061-1065.
32. Shanley JD. Modification of acute murine cytomegalovirus adrenal gland infection by adoptive spleen cell transfer. J Virol. 1987;61:23-28.
33. Duan Y, Ji Z, Atherton SS. Dissemination and replication of MCMV after supraciliary inoculation in immunosuppressed mice. Invest Ophthalmol Vis Sci. 1994;35:1124-1131.
34. Lu Y, Atherton SS. Immunization or adoptive transfer of immune cells protects against retinitis following supraciliary inoculation of murine cytomegalovirus (MCMV). In: Nussenblatt RB, Whitcup SM, Caspi RR, Gery I, eds. Advances in Ocular Immunology. Amsterdam: Elsevier B.V.; 1994:277-280.
35. Atherton SS, Newell CK, Kanter M, Cousins SW. Retinitis in euthymic mice following inoculation of murine cytomegalovirus (MCMV) via the supraciliary route. Curr Eye Res. 1991;10:667-677.
36. Igietseme JU, Calzada PJ, Gonzalez AR, Streilein JW, Atherton SS. Protection of mice from herpes simplex virus-induced retinitis by in vitro-activated immune cells. J Virol. 1989;63:4808-4813.
37. Kruisbeek AM. Isolation and fractionation of mononuclear cell populations. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, eds. Current Protocols in Immunology. New York: John Wiley and Sons; 1994:3.1.1-3.1.5.
38. Santamaria P, Lewis C, Barbosa JJ. Differences in the requirement of antigen-presenting cells for long-term growth among cytomegalovirus-specific Th clonotypes. Eur J Immunol. 1993;23:2972-2979.
39. Ksander BR, Miki S, Streilein JW, Podack E. Immune privilege and induction of tumor-specific effector T cells using IL-2 or IL-4 cDNA transfected tumor cells. In: Nussenblatt RB, Whitcup SM, Caspi RR, Gery I, eds. Advances in Ocular Immunology. Amsterdam: Elsevier B.V.; 1994:187-190.
40. Slezak SE, Horan PK. Fluorescent in vivo tracking of hematopoietic cells. Part 1. Technical considerations. Blood. 1989;74:2172-2177.
41. Teare GF, Horan PK, Slezak SE, Smith C, Hay JB. Long-term tracking of lymphocytes in vivo: The migration of PKH-labeled lymphocytes. Cell Immunol. 1991;134:157-170.
42. Samlowski WE, Robertson BA, Draper BK, Prystas E, McGregor JR. Effects of supravital fluorochromes used to analyze the in vivo homing of murine lymphocytes on cellular function. J Immunol Methods 1991;144:101-115.
43. Chin LT. Adult thymectomy. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, eds. Current Protocols in Immunology. New York: John Wiley and Sons; 1994:1.10.5-1.10.9.
44. + T lymphocytes. Invest Ophthalmol Vis Sci. 1994;35:54-63.
45. Hornbeck P. Assays for antibody production. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, eds. Current Protocols in Immunology. New York: John Wiley and Sons; 1994:2.1.1-2.1.22.
46. Loh L, Hudson JB. Interaction of murine cytomegalovirus with separated populations of spleen cells. Infect Immun. 1979;26:853-860.
47. Duan Y, Hernandez R, Pang L, Atherton SS. Disruption of the blood-retinal barrier increases spread of MCMV to the eye following intraperitoneal inoculation. Invest Ophthalmol Vis Sci. 1996;37:935-940.
48. + immune T cells. Immunol Lett. 1994;39:23-31.