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Volumn 49, Issue 2, 1997, Pages 169-177

Pharmacodynamic and pharmacokinetic studies in rats of S-8-(2-furyl)- and R-8-phenyl-2-(di-n-propylamino)tetralin, two novel 5-HT(1A) receptor agonists in-vitro with different properties in-vivo

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN; SEROTONIN 1A RECEPTOR; TETRALIN DERIVATIVE;

EID: 0031051918     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1997.tb06774.x     Document Type: Article
Times cited : (4)

References (31)
  • 2
    • 0028883970 scopus 로고
    • 5-Hydroxytryptamine and antidepressant augmentation
    • Artigas, F. (1995) 5-Hydroxytryptamine and antidepressant augmentation. Arch. Gen. Psychiatry 52: 969-971
    • (1995) Arch. Gen. Psychiatry , vol.52 , pp. 969-971
    • Artigas, F.1
  • 4
    • 0028287265 scopus 로고
    • Current advances and trends in the treatment of depression
    • Blier, P., De Montigny, C. (1994) Current advances and trends in the treatment of depression. Trends Pharmacol. Sci. 15: 220-226
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 220-226
    • Blier, P.1    De Montigny, C.2
  • 6
    • 0028245619 scopus 로고
    • Molecular biology of 5-HT receptors
    • Boess, F. G., Martin, I. L. (1994) Molecular biology of 5-HT receptors. Neuropharmacology 33: 275-317
    • (1994) Neuropharmacology , vol.33 , pp. 275-317
    • Boess, F.G.1    Martin, I.L.2
  • 7
    • 0015440803 scopus 로고
    • Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase
    • Carlsson, A., Davis, J. N., Kehr, W., Lindqvist, M., Atack, C. V. (1972) Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase. Naunyn Schmiedebergs Arch. Pharmacol. 275: 153-168
    • (1972) Naunyn Schmiedebergs Arch. Pharmacol. , vol.275 , pp. 153-168
    • Carlsson, A.1    Davis, J.N.2    Kehr, W.3    Lindqvist, M.4    Atack, C.V.5
  • 9
    • 0022555590 scopus 로고
    • 1A receptor-mediated inhibition of forskolin-stimulated adenylyl cyclase activity in guinea-pig and rat hippocampal membranes
    • 1A receptor-mediated inhibition of forskolin-stimulated adenylyl cyclase activity in guinea-pig and rat hippocampal membranes. J. Pharmacol. Exp. Ther. 238: 248-253
    • (1986) J. Pharmacol. Exp. Ther. , vol.238 , pp. 248-253
    • De Vivo, M.1    Maayani, S.2
  • 10
    • 0028990742 scopus 로고
    • 1A receptor agonists: Recent developments and controversial issues
    • 1A receptor agonists: recent developments and controversial issues. Psychopharmacology 121: 1-26
    • (1995) Psychopharmacology , vol.121 , pp. 1-26
    • De Vry, J.1
  • 16
    • 0024203466 scopus 로고
    • 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in-vivo
    • 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in-vivo. Naunyn Schmiedebergs Arch Pharmacol. 338: 463-471
    • (1988) Naunyn Schmiedebergs Arch Pharmacol. , vol.338 , pp. 463-471
    • Hjorth, S.1    Magnusson, T.2
  • 17
    • 14444271267 scopus 로고
    • 8-Hydroxy-2-di-n-propylaminotetralin, 8-OH-DPAT, a potent and selective simple ergot congener with 5-HT-receptor stimulating activity
    • Hjorth, S., Carlsson, A., Lindberg, P., Sanchez, D., Wikström, H., Arvidsson, L. E., Hacksell, U., Nilsson, J. L. G. (1982) 8-Hydroxy-2-di-n-propylaminotetralin, 8-OH-DPAT, a potent and selective simple ergot congener with 5-HT-receptor stimulating activity. J. Neural Transm. 55: 1690-1188
    • (1982) J. Neural Transm. , vol.55 , pp. 1690-11188
    • Hjorth, S.1    Carlsson, A.2    Lindberg, P.3    Sanchez, D.4    Wikström, H.5    Arvidsson, L.E.6    Hacksell, U.7    Nilsson, J.L.G.8
  • 18
    • 0024396619 scopus 로고
    • 1A agonist properties of the novel stereoselective 8-OH-DPAT analogue (+)cis-8-hydroxy-1-methyl-2-(di-n-propylamino) tetralin, (+)ALK-3
    • 1A agonist properties of the novel stereoselective 8-OH-DPAT analogue (+)cis-8-hydroxy-1-methyl-2-(di-n-propylamino) tetralin, (+)ALK-3. Eur. J. Pharmacol. 170: 269-274
    • (1989) Eur. J. Pharmacol. , vol.170 , pp. 269-274
    • Hjorth, S.1    Sharp, T.2    Hacksell, U.3
  • 22
    • 0023872441 scopus 로고
    • Distribution coefficient, a convenient term for the relation of predictable physicochemical properties to metabolic processes
    • Manners, C. N., Payling, D. W., Smith, D. A. (1988) Distribution coefficient, a convenient term for the relation of predictable physicochemical properties to metabolic processes. Xenobiotica 18: 331-350
    • (1988) Xenobiotica , vol.18 , pp. 331-350
    • Manners, C.N.1    Payling, D.W.2    Smith, D.A.3
  • 25
    • 0017600519 scopus 로고
    • Transport of metabolic substrates through the blood-brain barrier
    • Pardridge, W. M., Oldendorf, W. H. (1977) Transport of metabolic substrates through the blood-brain barrier. J. Neurochem. 28: 5-12
    • (1977) J. Neurochem. , vol.28 , pp. 5-12
    • Pardridge, W.M.1    Oldendorf, W.H.2
  • 26
    • 14444275486 scopus 로고
    • Molecular biology of serotonin (5-HT) receptors
    • Peroutka, S. J. (1994) Molecular biology of serotonin (5-HT) receptors. Synapse 210: 88-90
    • (1994) Synapse , vol.210 , pp. 88-90
    • Peroutka, S.J.1
  • 27
    • 0028301989 scopus 로고
    • A mechanism for P-glycoprotein action in multidrug resistance: Are we there yet?
    • Ruetz, S., Gros, P. (1994) A mechanism for P-glycoprotein action in multidrug resistance: are we there yet? Trends Pharmacol. Sci. 15: 260
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 260
    • Ruetz, S.1    Gros, P.2
  • 28
    • 0024427774 scopus 로고
    • Pharmacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis
    • Sharp, T., Bramwell, S. R., Hjorth, S., Grahame-Smith, D. G. (1989) Pharmacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis. Br. J. Pharmacol. 98: 989-997
    • (1989) Br. J. Pharmacol. , vol.98 , pp. 989-997
    • Sharp, T.1    Bramwell, S.R.2    Hjorth, S.3    Grahame-Smith, D.G.4
  • 29
    • 0028789369 scopus 로고
    • Antidepressants: Clinical and neuropharmacologic considerations relevant to future drug discovery and development
    • Temple, D. L. (1995) Antidepressants: clinical and neuropharmacologic considerations relevant to future drug discovery and development. Exp. Opin. Invest. Drugs 4: 909-914
    • (1995) Exp. Opin. Invest. Drugs , vol.4 , pp. 909-914
    • Temple, D.L.1
  • 30
    • 0027290876 scopus 로고
    • Restricted transport of cyclosporin A across the blood-brain-barrier by a multidrug transporter, P-glycoprotein
    • Tsuji, A., Tamai, I., Sakata, A., Tenda, Y., Terasaki, T. (1993) Restricted transport of cyclosporin A across the blood-brain-barrier by a multidrug transporter, P-glycoprotein. Biochem. Pharmacol. 46: 1096-1099
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 1096-1099
    • Tsuji, A.1    Tamai, I.2    Sakata, A.3    Tenda, Y.4    Terasaki, T.5
  • 31
    • 0030975832 scopus 로고    scopus 로고
    • Pharmacodynamic and pharmacokinetic studies of R-8-hydroxy-2-(di-n-propylamino)tetralin in the rat
    • In press
    • Yu, H., Lewander, T. (1997) Pharmacodynamic and pharmacokinetic studies of R-8-hydroxy-2-(di-n-propylamino)tetralin in the rat. Eur Neuropsychopharmacol. In press
    • (1997) Eur Neuropsychopharmacol.
    • Yu, H.1    Lewander, T.2


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