Active catabolism of glucocorticoids by 11β-hydroxysteroid dehydrogenase in vivo is a necessary requirement for natural resistance to infection with Listeria monocytogenes

International Immunology

Volumn 9, Issue 1, 1997, Pages 105-115

  Hennebold, Jon D ^a   Mu, Hong Hua ^a   Poynter, Matthew E ^a   Chen, Xiao Ping ^a   Daynes, Raymond A ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

11 hydroxysteroid dehydrogenase; Corticosterone; Cytokines; Glucocorticoids; Listeria monocytogenes

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CYTOKINE; DEXAMETHASONE; GLUCOCORTICOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; CATABOLISM; CONTROLLED STUDY; DEFENSE MECHANISM; ENZYME INHIBITION; FEMALE; HOST SUSCEPTIBILITY; INFECTION RESISTANCE; INFECTION SENSITIVITY; LISTERIA MONOCYTOGENES; LISTERIOSIS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; CYTOKINES; DISEASE SUSCEPTIBILITY; FEMALE; GLUCOCORTICOIDS; HYDROXYSTEROID DEHYDROGENASES; IMMUNITY, NATURAL; LISTERIA INFECTIONS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL;

EID: 0031051677     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/9.1.105     Document Type: Article

References (54)

1. Sher, A. and Coffman, R. L. 1992. Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu. Rev. Immunol. 10:385.
2. + T cells through IL-12 produced by Listeria-induced macrophages. Science 260:547.
3. Heinzel, F. P., Sadick, M. D., Holaday, B. J., Coffman, R. L. and Locksley, R. M. 1989 Reciprocal expression of interferon γ or interleukin 4 during the resolution or progression of murine Leishmaniasis. J. Exp. Med. 169:59.
4. Yoshida, A., Koide, Y, Uchijima, M. and Yoshida, T. O. 1995. Dissection of strain difference in acquired protective immunity against Mycobacterium bovis calmette-guérin bacillus (BCG). Macrophages regulate the susceptibility through cytokine network and the induction of nitric oxide synthase. J. Immunol. 155:2057.
5. Kaufman, S. H. 1993. Immunity to intracellular bacteria. Annu. Rev. Immunol. 11:129.
6. Bancroft, G. J., Schreiber, R. D. and Unanue, E. R. 1991. Natural immunity: a T cell-independent pathway of macrophage activation, defined in the scid mouse. Immunol. Rev. 124:5.
7. Liu, Z., Simpson, R. J. and Cheers, C 1992. Recombinant interleukin-6 protects mice against experimental bacterial infection. Infect. Immun. 60:4402.
8. Bancroft, G. J., Schreiber, R. D., Bosma, C. G., Bosma, M. J. and Unanue, E. R. 1987. A T cell-independent mechanism of macrophage activation by interferon-γ. J. Immunol 139:1104.
9. Tripp, C. S., Wolf, S. F. and Unanue, E. R. 1993. Interleukin 12 and tumor necrosis factor α are costimulators of interferon γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc. Natl Acad. Sci. USA 90:3725.
10. Beckerman, K. P., Rogers, H. W., Corbett, J. A., Schreiber, R. D., McDaniel, M. L. and Unanue, E. R. 1993. Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes. J. Immunol. 150:888.
11. Boockvar, K. S., Granger, D. L., Poston, R. M., Maybodi, M., Washington, M. K., Hibbs, J. B., Jr and Kurlander, R. L. 1994. Nitric oxide produced during murine Listeriosis is protective. Infect. Immun. 62:1089.
12. Tripp, C. S., Gately, M. K., Hakimi, J., Ling, P. and Unanue, E. R. 1994. Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-γ. J. Immunol. 152:1883.
13. Cupps, T. R. 1989. Effects of glucocorticoids on lymphocyte function. In Schleimer, R. P., Clamen, H. N. and Oronsky, A., eds, Anti-inflammatory Steroid Action. p. 132. Academic Press, San Diego.
14. Schaffner, A., Douglas, H. and Davis, C. E. 1983. Models of T cell deficiency in listeriosis: the effects of cortisone and cyclosporin A on normal and nude BALB/c mice. J. Immunol. 131:450.
15. Beutler, B., Krochin, N., Milsark, I. W., Luedke, C. and Cerami, A. 1986. Control of cachectin (tumor necrosis factor) synthesis: mechanism of endotoxin resistance. Science 232:977.
16. Ray, A., LaForge K. S. and Sehgal, P. B. 1990. On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: enhancer, TATA box, and RNA start site (Inr motif) occlusion. Mol. Cell. Biol. 10:5736.
17. Snyder, D. S. and Unanue, E. R. 1982. Corticosteroids inhibit murine macrophage la expression and interleukin 1 production. J. Immunol. 129:1803.
18. Arya, S. K., Wong-Staal, F. and Gallo, R. C. 1984. Dexamethasone-mediated inhibition of human T cell growth factor and gamma-interferon messenger RNA. J. Immunol. 133:273.
19. Rosa, M. D., Radomski, M., Carnuccio, R. and Moncada, S. 1990. Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages. Biochem. Biophys. Res. Comm. 172:1246.
20. Oursler, M. J., Riggs, B. L. and Spelslaerg, T. C. 1993. Glucocorticoid-induced activation of latent transforming growth factor-β by normal human osteoblast-like cells. Endocrinology 133:2187.
21. Errasfa, M. and Russo-Marie, F 1989. A purified lipocortin shares the anti-inflammatory effect of glucocorticosteroids in vivo in mice. Br. J. Pharmacol. 97:1051.
22. Daynes, R. A. and Araneo, B. A. 1989. Contrasting effects of glucocorticoids on the capacity of T cells to produce interleukin 2 and interleukin 4. Eur. J. Immunol. 19:2319
23. Hennebold, J. D., Ryu, S.-Y., Mu, H.-H., Galbraith, A. and Daynes, R. A. 1996. 11β-Hydroxysteroid dehydrogenase modulation of glucocorticoid activities in lymphoid organs. Am. J. Physiol. 270:R1296.
24. + T cells in vitro. J. Immunol. 156:2406.
25. Kelly, J. P. and Bancroft, G. J. 1996. Administration of interleukin-10 abolishes innate resistance to Listeria monocytogenes. Eur. J. Immunol. 26:356.
26. Reichlin, S. 1993. Neuroendocrine-immune interactions. New Engl. J. Med. 329:1246.
27. Monder, C. and White, P. C. 1993. 11β-Hydroxysteroid dehydrogenase. Vitam. Horm. 47:187.
28. Murphy, B. E. P. 1981. Ontogeny of cortisol-cortisone interconversion in human tissues: a role for cortisone in human fetal development. J. Steroid Biochem. 14:811.
29. Rajan, V., Chapman, K. E., Lyons, V., Jamieson, P., Mullins, J. J., Edwards, C. R. W. and Seckl, J. R. 1995. Cloning, sequencing and tissue-distribution of mouse 11β-hydroxysteroid dehydrogenase-1 cDNA. J. Steroid Biochem. Mol. Biol. 52:141.
30. Cole, T. J. 1995. Cloning of the mouse 11β-hydroxysteroid dehydrogenase type 2 gene: tissue-specific expression and localization in distal convoluted tubules and collecting ducts of the kidney. Endocrinology 136:4693.
31. Gomez-Sanchez, E. P., Cox, D., Foecking, M., Ganjam, V. and Gomez-Sanchez, C. E. 1996. 11β-hydroxysteroid dehydrogenase of the choriocarcinoma cell line JEG-3 and their inhibition by glycyrrhetinic acid and other natural substances. Steroids 61:110.
32. Liu, Z. and Cheers, C. 1993. The cellular source of interleukin-6 during Listeria infection. Infect. Immun. 61:2626.
33. Schumacher, J. H., O'Garra, A., Shrader, B., van Kimmenade, A., Bond, M. W., Mosmann, T. R. and Coffman, R. L. 1988. The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J. Immunol. 141:1576.
34. Daynes, R. A., Dowell, T. and Araneo, B. A. 1991. Platelet-derived growth factor is a potent biologic response modifier of T cells. J. Exp. Med. 174:1323.
35. Chomczynski, P. and Sacchi, N. 1987. Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156.
36. Spencer, N. F. L., Norton, S. D., Harrison, L. L., Li, G.-L. and Daynes, R. A. 1995. Dysregulation of IL-10 production with aging: possible linkage to the age-associated decline in DHEA and its sulfated derivative. Exp. Gerontol. 31:393.
37. Marandici, A. and Monder, C. 1993. Inhibition by glycyrrhetinic acid of rat tissue 11β-hydroxysteroid dehydrogenase in vivo. Steroids 58:153.
38. Cheers, C., McKenzie, I. F. C., Pavlov, H., Waid, C. and York, J. 1978. Resistance and susceptibility of mice to bacterial infection: course of listeriosis in resistant or susceptible mice. Infect. Immun. 19:763.
39. Monder, C., Stewart, P. M., Lakshmi, V., Valentino, R., Burt, D. and Edwards, C. R. W. 1989. Licorice inhibits corticosteroid 11β-dehydrogenase of rat kidney and liver: in vivo and in vitro studies. Endocrinology 125:1046.
40. Mainwaring, W. I. P. 1977. The model for the mechanism of action of androgens. In Gross, F., Grumbach, M. M., Labhart, A., Lipsett, M. B. and Mann, T., eds, Mechanism of Action of Androgen, p. 23. Springer, New York.
41. Labrie, F., Sugimaoto, Y., Luu-The, V., Simard, J., Lachance, Y., Bacharov, D., Leblanc, G., Durocher, F. and Paquet, N. 1992. Structure of human type II 5α-reductase gene. Endocrinology 131:1571.
42. 3 production. J. Steroid Biochem. Mol. Biol. 41:401.
43. Leid, M., Kastner, P. and Chambon, P. 1992. Multiplicity generates diversity in the retinoic acid signaling pathways, Trends Biochem. Sci. 17:427.
44. Hennebold, J. D. and Daynes, R. D. 1994. Regulation of macrophage dehydroepiandrosterone sulfate metabolism by inflammatory cytokines. Endocrinology 135:67.
45. Gillis, S., Crabtree, G. R. and Smith, K. A. 1979. Glucocorticoid-induced inhibition of T cell growth factor production I. The effect on mitogen-stimulated lymphocyte proliferation. J. Immunol. 123:1624.
46. Tripp, C. S., Kanagawa, O. and Unanue, E. R. 1995. Secondary response to Listeria infection requires IFN-γ but is partially independent of IL-12. J. Immunol. 155:3427.
47. Mercer, W. R. and Krozowski, Z. S. 1992. Localization of an 11β-hydroxysteroid dehydrogenase activity in the distal nephron. Evidence for the existence of two species of dehydrogenase in the rat kidney. Endocrinology 130:540.
48. Moisan, M.-P., Seckl, J. R. and Edwards, C. R. W. 1990. 11β-hydroxysteroid dehydrogenase bioactivity and messenger RNA expression in rat forebrain: localization in hypothalamus, hippocampus, and cortex. Endocrinology 127:1450.
49. Cher, D. J. and Mosmann, T. R. 1987. Two types of murine helper T cell clone. II. Delayed type hypersensitivity is mediated by Th1 clones. J. Immunol. 138:3688.
50. Thoman, M. L. and Weigle, W. O. 1989. The cellular and subcellular basis of immunosenescence. Adv. Immunol. 46:221.
51. Daynes, R. A., Araneo, B. A., Hennebold, J., Enioutina, E. and Mu, H. H. 1995. Steroids as regulators of the mammalian immune response. J. Invest. Dermatol. 105:14S.
52. Boom, W. H., Liebster, L., Abbas, A. K. and Titus, R. G. 1990. Patterns of cytokine secretion in murine leishmaniasis: correlation with disease progression or resolution. Infect. Immun. 58:3863.
53. MacPhee, I. A. M., Antoni, F. A. and Mason, D. W. 1989. Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids. J. Exp. Med. 169:431.
54. Mason, D., MacPhee, I. and Antoni, F. 1990. The role of the neuroendocrine system in determining genetic susceptibility to experimental allergic encephalomyelitis in the rat. Immunology 70:1.