Complex architecture of major histocompatibility complex class II promoters: Reiterated motifs and conserved protein-protein interactions

Molecular and Cellular Biology

Volumn 16, Issue 9, 1996, Pages 4683-4690

  Jabrane Ferrat, Nabila ^a   Fontes, Joseph D ^a   Boss, Jeremy M ^b   Peterlin, B Matija ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HYBRID PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; GENE EXPRESSION; LYMPHOMA CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION;

EID: 0029762163     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.9.4683     Document Type: Article

References (52)

1. Abdulkadir, S. A., and S. J. Ono. 1995. How are class II MHC genes turned on and off? FASEB J. 9:1429-1435.
2. Accolla, R. S., M. D. Scupoli, C. Cambiaggi, G. Tosi, and S. Sartoris. 1991. Cell lineage-specific and developmental stage-specific controls of MHC class-II-antigen expression. Int. J. Cancer 6(Suppl.):20-25.
3. Andersson, G., and B. M. Peterlin. 1990. NF-X2 that binds to the DRA X2-box is activator protein 1. Expression cloning of c-Jun. J. Immunol. 145: 3456-3462.
4. Benoist, C., and D. Mathis. 1990. Regulation of major histocompatibility complex class-II genes: X, Y, and other letters of the alphabet. Annu. Rev. Immunol. 8:681-715.
5. Chang, C. H., J. D. Fontes, B. M. Peterlin, and R. A. Flavell. 1994. Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. J. Exp. Med. 180:1367-1374.
6. Cogswell, J. P., J. Austin, and J. P. Ting. 1991. The W element is a positive regulator of HLA-DRA transcription in various DR+ cell types. J. Immunol. 146:1361-1367.
7. Cogswell, J. P., P. V. Basta, and J. P. Ting. 1990. X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements. Proc. Natl. Acad. Sci. USA 87:7703-7707.
8. Cogswell, J. P., N. Zeleznik-Le, and J. P. Ting. 1991. Transcriptional regulation of the HLA-DRA gene. Crit. Rev. Immunol. 11:87-112.
9. Cress, W. D., and S. J. Triezenberg. 1991. Critical structural elements of the VP16 transcriptional activation domain. Science 251:87-90.
10. Cresswell, P. 1994. Assembly, transport, and function of MHC class II molecules. Annu. Rev. Immunol. 12:259-293.
11. Durand, B., M. Kobr, W. Reith, and B. Mach. 1994. Functional complementation of major histocompatibility complex class II regulatory mutants by the purified X-box-binding protein RFX. Mol. Cell. Biol. 14:6839-6847.
12. Fontes, J. D., and B. M. Peterlin. Unpublished data.
13. Glimcher, L. H., and C. J. Kara. 1992. Sequences and factors: a guide to MHC class-II transcription. Annu. Rev. Immunol. 10:13-49.
14. Griffin, G. E., K. Leung, T. M. Folks, S. Kunkel, and G. J. Nabel. 1991. Induction of NF-κB during monocyte differentiation is associated with activation of HIV-gene expression. Res. Virol. 142:233-238.
15. Grosschedl, R. 1995. Higher-order nucleoprotein complexes in transcription: analogies with site-specific recombination. Curr. Opin. Cell Biol. 7:362-370.
16. Hasegawa, S. L., and J. M. Boss. 1991. Two B cell factors bind the HLA-DRA X box region and recognize different subsets of HLA class II promoters. Nucleic Acids Res. 19:6269-6276.
17. Hayes, S., and P. O'Hare. 1993. Mapping of a major surface-exposed site in herpes simplex virus protein Vmw65 to a region of direct interaction in a transcription complex assembly. J. Virol. 67:852-862.
18. Jabrane-Ferrat, N., and B. M. Peterlin. 1994. Ets-1 activates the DRA promoter in B cells. Mol. Cell. Biol. 14:7314-7321.
19. Kappes, D., and J. L. Strominger. 1988. Human class II major histocompatibility complex genes and proteins. Annu. Rev. Biochem. 57:991-1028.
20. Kara, C. J., and L. H. Glimcher. 1991. In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome. Science 252:709-712.
21. Liou, H. C., M. R. Boothby, P. W. Finn, R. Davidon, N. Nabavi, N. J. Zeleznik-Le, J. P. Ting, and L. H. Glimcher. 1990. A new member of the leucine zipper class of proteins that binds to the HLA DR a promoter. Science 247:1581-1584.
22. Mantovani, R., L. Tora, V. Moncollin, J. M. Egly, C. Benoist, and D. Mathis. 1993. The major histocompatibility complex (MHC) Eα promoter: sequences and factors at the initiation site. Nucleic Acids Res. 21:4873-4878.
23. Moreno, C. S., P. Emery, J. E. West, B. Durand, W. Reith, B. Mach, and J. M. Boss. 1995. Purified X2 binding protein (X2BP) cooperatively binds the class II MHC X box region in the presence of purified RFX, the X box factor deficient in the bare lymphocyte syndrome. J. Immunol. 155:4313-4321.
24. Peterlin, B. M., G. Andersson, E. Lotscher, and S. Tsang. 1990. Transcriptional regulation of HLA class-II genes. Immunol. Res. 9:164-177.
25. Reith, W., E. Barras, S. Satola, M. Kobr, D. Reinhart, C. H. Sanchez, and B. Mach. 1989. Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation. Proc. Natl. Acad. Sci. USA 86:4200-4204.
26. Reith, W., C. Herrero-Sanchez, M. Kobr, P. Silacci, C. Berte, E. Barras, S. Fey, and B. Mach. 1990. MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain. Genes Dev. 4:1528-1540.
27. Reith, W., M. Kobr, P. Emery, B. Durand, C. A. Siegrist, and B. Mach. 1994. Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters. J. Biol. Chem. 269:20020-20025.
28. Reith, W., C. A. Siegrist, B. Durand, E. Barras, and B. Mach. 1994. Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y. Proc. Natl. Acad. Sci. USA 91: 554-558.
29. Reith, W., V. Steimle, and B. Mach. 1995. Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes. Immunol. Today 16:539-546.
30. Schwartz, R. H. 1985. T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex. Annu. Rev. Immunol. 3:237-261.
31. Schwartz, R. H. 1986. Immune response (Ir) genes of the murine major histocompatibility complex. Adv. Immunol. 38:31-201.
32. Servenius, B., L. Rask, and P. A. Peterson. 1987. Class II genes of the human major histocompatibility complex. The DOβ gene is a divergent member of the class II β gene family. J. Biol. Chem. 262:8759-8766.
33. Shapiro, D. J., P. A. Sharp, W. W. Wahli, and M. J. Keller. 1988. A high-efficiency HeLa cell nuclear transcription extract. DNA 7:47-55.
34. Sherman, P. A., P. V. Basta, A. Heguy, M. K. Wloch, R. G. Roeder, and J. P. Ting. 1989. The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DRα gene promoter. Proc. Natl. Acad. Sci. USA 86:6739-6743.
35. Siegrist, C. A., B. Durand, P. Emery, E. David, P. Hearing, B. Mach, and W. Reith. 1993. RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer. Mol. Cell. Biol. 13:6375-6384.
36. Steimle, V., B. Durand, E. Barras, M. Zufferey, M. R. Hadam, B. Mach, and W. Reith. 1995. A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome). Genes Dev. 9:1021-1032.
37. Steimle, V., L. A. Otten, M. Zufferey, and B. Mach. 1993. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell 75:135-146.
38. Steimle, V., C. A. Siegrist, A. Mottet, B. Lisowska-Grospierre, and B. Mach. 1994. Regulation of MHC class II expression by interferon-γ mediated by the transactivator gene CIITA. Science 265:106-109.
39. Stimac, E., S. Lyons, and D. Pious. 1988. Transcription of HLA class II genes in the absence of B cell-specific octamer-binding factor. Mol. Cell. Biol. 8:3734-3739.
40. Sucov, H. M., and R. M. Evans. 1995. Retinoic acid and retinoic acid receptors in development. Mol. Neurobiol. 10:169-184.
41. Thanos, D., and T. Maniatis. 1995. Virus induction of human IFN β gene expression requires the assembly of an enhanceosome. Cell 83:1091-1100.
42. Treisman, R. 1995. Journey to the surface of the cell: Fos regulation and the SRE. EMBO J. 14:4905-4913.
43. Tsang, S. Y., M. Nakanishi, and B. M. Peterlin. 1988. B cell-specific and interferon-γ-inducible regulation of the HLA-DRα gene. Proc. Natl. Acad. Sci. USA 85:8598-8602.
44. Tsang, S. Y., M. Nakanishi, and B. M. Peterlin. 1990. Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors. Mol. Cell. Biol. 10:711-719.
45. van Huijsduijnen, R. H., X. Y. Li, D. Black, H. Matthes, C. Benoist, and D. Mathis. 1990. Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits. EMBO J. 9:3119-3127.
46. Vilen, B. J., J. P. Cogswell, and J. P.-Y. Ting. 1991. Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function. Mol. Cell. Biol. 11:2406-2415.
47. Vilen, B. J., J. F. Penta, and J. P. Ting. 1992. Structural constraints within a trimeric transcriptional regulatory region. Constitutive and interferon-γ-inducible expression of the HLA-DRA gene. J. Biol. Chem. 267:23728-23734.
48. Viville, S., V. Jongeneel, W. Koch, R. Mantovani, C. Benoist, and D. Mathis. 1991. The E α promoter: a linker-scanning analysis. J. Immunol. 146:3211-3717.
49. Voliva, C. F., A. Aronheim, M. D. Walker, and B. M. Peterlin. 1992. B-cell factor 1 is required for optimal expression of the DRA promoter in B cells. Mol. Cell. Biol. 12:2383-2390.
50. Voliva, C. F., N. Jabrane-Ferrat, and B. M. Peterlin. 1996. The function of the octamer binding site in the DRA promoter. Immunogenetics 43:20-26.
51. Yu, V. C., A. M. Naar, and M. G. Rosenfeld. 1992. Transcriptional regulation by the nuclear receptor superfamily. Curr. Opin. Biotechnol. 3:597-602.
52. Zhang, X. Y., N. Jabrane-Ferrat, C. K. Asiedu, S. Samac, B. M. Peterlin, and M. Ehrlich. 1993. The major histocompatibility complex class II promoter-binding protein RFX (NF-X) is a methylated DNA-binding protein. Mol. Cell. Biol. 13:6810-6818.