K-ras mutation in adenomas and carcinomas of the ampulla of Vater

Clinical Cancer Research

Volumn 3, Issue 1, 1997, Pages 129-133

  Howe, James R ^a   Klimstra, David S ^b   Cordon Cardo, Carlos ^b   Paty, Philip B ^b   Park, Patrick Y ^b   Brennan, Murray F ^b  

^a UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOMA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; META ANALYSIS; MUTATION; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR VOLUME; VATER PAPILLA CARCINOMA;

ADENOMA; AMPULLA OF VATER; CARCINOMA; COMMON BILE DUCT NEOPLASMS; GENES, RAS; HUMANS; MUTATION; TIME FACTORS;

EID: 0031049682     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Brennan, M. F. Surgical management of peripancreatic cancer. In: K. I. Bland, C. P. Karakousis, and E. M. Copeland (eds.), Atlas of Surgical Oncology, pp. 473-485. Philadelphia: W. B. Saunders Co., 1995.
2. Matory, Y. L., Gaynor, J., and Brennan, M. F. Carcinoma of the ampulla of Vater. Surg. Gynecol. Obstet., 177: 366-370, 1993.
3. Kozuka, S., Tsubone, M., Yamaguchi, A., and Hachisuka, K. Adenomatous residue in cancerous papilla of Vater. Gut, 22: 1031-1034, 1981.
4. Forrester, K., Almoguera, C., Han, K., Grizzle, W. E., and Perucho, M. Detection of high incidence of K-ras oncogenes during human colorectal tumorigenesis. Nature (Lond.), 327: 298-303, 1987.
5. Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Leppert, M., Nakamura, Y., White, R., Smits, A. M. M., and Bos, J. L. Genetic alterations during colorectal tumor development. N. Engl. J. Med., 319: 525-532, 1988.
6. Burmer, G. C, and Loeb, L. A. Mutations in the KRAS2 oncogene during the progressive stages of human colon carcinoma. Proc, Natl. Acad. Sci. USA, 86: 2403-2407, 1989.
7. Capella, G., Cronauer-Mitra, S., Peinado, M. A., and Perucho, M. Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors. Environ. Health Perspect., 93: 125-131, 1991.
8. Finklestein, S. D., Sayegh, R., Christensen, S., and Swalsky, P. A. Genotypic classification of colorectal adenocarcinoma. Cancer (Phila.), 77:3827-3838, 1993.
9. Breivik, J., Meling, G. I., Spurkland, A., Rognum, T, O., and Gaudernack, G. K-ras mutation in colorectal cancer: relations to patient age, sex, and tumour location. Br. J. Cancer, 69: 367-371, 1994.
10. Almoguera, C., Shibata, D., Forrester, K., Martin, J., Arnheim, N., and Perucho, M. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell, 53: 549-554, 1988.
11. Smit, V. T. H. B. M., Boot, A. J. M., Smits, A. M. M., Fleuren, G. J., Cornelisse, C. J., and Bos, J. L. KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas. Nucleic Acids Res., 16: 7773-7782, 1988.
12. Motojima, K., Urano, T., Nagata, Y., Shiku, H., Tsurifune, T., and Kanematsu, T. Detection of point mutations in the Kirsten-rar oncogene provides evidence for the multicentricity of pancreatic carcinoma. Ann. Surg., 277: 138-143, 1993.
13. Hruban, R. H., van Mansfield, A. D. M., Offerhaus, G. J. A., van Wearing, D. H. J., Allison, D. C., Goodman, S. N., Kensler, T. W., Bose, K. K., Cameron, J, L., and Bos, J. L. K-ras oncogene activation in adenocarcinoma of the human pancreas. Am. J. Pathol., 143: 545-554, 1993.
14. Yashiro, T., Fulton, N., Hara, H., Yasuda, K., Montag, A., Yashiro. N., Straus, F., Ito, K., Aiyoshi, Y., and Kaplan, E. L. Comparison of mutations of ras oncogene in human pancreatic exocrine and endocrine tumors. Surgery (St. Louis), 114: 758-764, 1993.
15. Pellegata, N. S., Sessa, F., Renault, B., Bonato, M., Leone. B. E., Solcia, E., and Ranzani, G. N. K-ras as and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions. Cancer Res., 54: 1556-1560, 1994.
16. Motojima, K., Urano, T., Nagata, Y., Shiku, H., Tsunoda, T., and Kanematsu, T. Mutations in the Kirsten-ras oncogene are common but lack correlation with prognosis and tumor stage in human pancreatic carcinoma. Am. J. Gastroenterol., 86: 1784-1788, 1991.
17. Finklestein, S. D., Przygodzki, R., Pricolo, V. E., Sayegh, R., Bakker, A., Swalsky, P. A., and Keller, G. K-ras-2 topographic genotyping of pancreatic adenocarcinoma. Arch. Surg., 129: 367-372, 1994.
18. Kern, S. E., Fearon, E. R., Tersmette, K. W. F., Enterline, J. P., Leppert, M., Nakamura, Y., White, R., Vogelstein, B., and Hamilton, S. R. Allelic loss in colorectal carcinoma. J. Am. Med. Assoc., 261: 3099-3103, 1989.
19. Laurent-Puig, P., Olschwang, S., Delattre, O., Remvikos, Y., Asselain, B., Melot, T., Validire, P., Muleris, M., Girodet, J., Salmon, R. J., and Thomas, G. Survival and acquired genetic alterations in colorectal cancer. Gastroenterology, 102: 1136-1141, 1992.
20. Motojima, K., Tsunoda, T., Kanematsu, T., Nagata, Y., Urano, T., and Shiku, H. Distinguishing pancreatic carcinoma from other periampullary carcinomas by analysis of mutations in the Kirsten-ras oncogene. Ann. Surg., 214: 657-662, 1991.
21. Stork, P., Loda, M., Bosari, S., Wiley, B., Poppenhusen, K., and Wolfe, H. Detection of K-ras mutations in pancreatic and hepatic neoplasms by non-isotopic mismatched polymerase chain reaction. Oncogene, 6: 857-862, 1991.
22. Scarpa, A., Capelli, P., Zamboni, G., Bonetti, F., Martignoni, G., Iacono, C., Serio, G., and Hirohashi, S. Neoplasia of the ampulla of Vater. Ki-ras and p53 mutations. Am. J. Pathol., 142: 1163-1172, 1993.
23. Scarpa, A., Zamboni, G., Achille, A., Capelli, P., Bogino, G., Iacono, C., Serio, G., and Accolla, R. S. ras-family gene mutations in neoplasia of the ampulla of Vater. Int. J. Cancer, 59: 39-42, 1994.
24. Verlaan-de Vries, M., Bogaard, M. E., van den Elst, H., van Boom, J. H., van der Eb, A. J., and Bos, J. L. A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides. Gene (Amst.), 50: 313-320, 1986.
25. Grunewald, K., Lyons, J., Frohlich, A., Feichtinger, H., Weger, R. A., Schwab, G., Janssen, J. W. G., and Bartram, C. R. High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas. Int. J. Cancer, 43: 1037-1041, 1989.
26. Tada, M., Yokosuka, O., Omata, M., Ohto, M., and Isono, K. Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing. Cancer (Phila.), 66: 930-935, 1990.
27. Nagata, Y., Abe, M., Motoshima, K., Nakayama, E., and Shiku, H. Frequent glycine to aspartic acid mutations at codon 12 of c-Ki-ras gene in human pancreatic cancer in Japanese. Jpn. J. Cancer Res., 81: 135-140, 1990.
28. Lemoine, N. R., Jain, S., Hughes, C. M., Staddon, S. L., Maillet, B., Hall, P. A., and Kloppel, G. Ki-ras oncogene activation in preinvasive pancreatic cancer. Gastroenterology, 102: 230-236, 1992.
29. Hoshi, T., Imai, M., and Ogawa, K. Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas. J. Surg. Oncol., 55: 84-91, 1994.
30. Scarpa, A., Capelli, P., Villaneuva, A., Zamboni, G., Accolla, R., Mariuzzi, G., and Capella, G. Pancreatic cancer in Europe; Ki-ras gene mutation pattern shows geographical differences. Int. J. Cancer, 57: 167-171, 1994.
31. Berrozpe, G., Schaeffer, J., Peinado, M. A., Real, F. X., and Perucho, M. Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer. Int. J. Cancer, 58: 185-191, 1994.
32. Howe, J. R., and Conlon, K. C. The molecular genetics of pancreatic cancer. Surg. Oncol., in press, 1997.
33. Baczako, K., Buchler, M., Beger, H-G., Kirkpatrick, C. J., and Haferkamp, O. Morphogenesis and possible precursor lesions of invasive carcinoma of the papilla of Vater: epithelial dysplasia and adenoma. Hum. Pathol., 16: 305-310, 1985.
34. Gallinger, S., Vivona, A. A., Odze, R. D., Mitri, A., O'Beirne, C. P., Berk, T. C., and Bapat, B. V. Somatic APC and K-w codon 12 mutations in periampullary adenomas and carcinomas from familial adenomatous polyposis patients. Oncogene, 10: 1875-1878, 1995.
35. Yanagisawa, A., Oh take, K., Ohashi, K., Hori, M., Kitagawa, T., Sugano, H., and Kato, Y. Frequent c-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation. Cancer Res., 53: 953-956, 1993.
36. Allema, J. H., Reinders, M. E., van Gulik, T. M., van Leeuwen, D. J., Verbeek, P. C. M., de Wit, L. T., and Gouma, D. J. Results of pancreaticoduodenectomy for ampullary carcinoma and analysis of prognostic factors for survival. Surgery (St. Louis), 117: 247-253, 1995.
37. Finklestein, S. D., Sayegh, R., Bakker, A., and Swalsky, P. Determination of tumor aggressiveness in colorectal cancer by K-ras-2 analysis. Arch. Surg., 128: 526-532, 1993.
38. Benhatter, J., Losi, L., Chaubert, P., Givel, J-C. and Costa, J. Prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology, 104: 1044-1048, 1993.
39. Delcore, R., Connor, C. S., Thomas, J. H., Friesen, S. R., and Hermreck, A. S. Significance of tumor spread in adenocarcinoma of the ampulla of Vater. Am. J. Surg., 158: 593-597, 1989.
40. Martin, M., Rossi, R. L., Dorucci, V., Silverman, M. L., and Braasch, J. W. Clinical and pathologic correlations in patients with periampullary tumors. Arch. Surg., 125; 723-726, 1990.
41. Roder, J. D., Schneider, P. M., Stein, H. J., and Siewert, J. R. Number of lymph node metastases is significantly correlated with survival in patients with radically resected carcinoma of the ampulla of Vater. Br. J. Surg., 82: 1693-1696, 1995.
42. Shibata, D., Almoguera, C., Forrester, K., Dunitz, J., Martin, S. E., Cosgrove, M. M., Perucho, M., and Amheim, N. Detection of c-K-ras mutations in fine needle aspirates from human pancreatic adenocarcinomas. Cancer Res., 50: 1279-1283, 1990.