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Volumn 9, Issue 3, 1997, Pages 373-380

Effect of different Ig transgenes on B cell differentiation in scid mice

Author keywords

DNA double strand breaks; L chain locus; V(D)J recombination

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; COMBINED IMMUNODEFICIENCY; DNA STRAND BREAKAGE; GENE REARRANGEMENT; IMMUNOGLOBULIN GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; TRANSGENIC MOUSE;

EID: 0031049661     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/9.3.373     Document Type: Article
Times cited : (6)

References (61)
  • 1
    • 0027769386 scopus 로고
    • Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated
    • Schlissel, M., Constantinescu, A., Morrow, T., Baxter M. and Peng, A. 1993. Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated. Genes Dev. 7:2520.
    • (1993) Genes Dev. , vol.7 , pp. 2520
    • Schlissel, M.1    Constantinescu, A.2    Morrow, T.3    Baxter, M.4    Peng, A.5
  • 2
    • 0026792892 scopus 로고
    • V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
    • Roth, D. B., Menetski, J. P., Nakajima, P. B., Bosma, M. J. and Gellert, M. 1992. V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes. Cell 70:983.
    • (1992) Cell , vol.70 , pp. 983
    • Roth, D.B.1    Menetski, J.P.2    Nakajima, P.B.3    Bosma, M.J.4    Gellert, M.5
  • 5
    • 0026018228 scopus 로고
    • T-lymphocyte development in scid mice is arrested shortly after the initiation of T-cell receptor δ gene recombination
    • Carroll, A. and Bosma, M. J. 1991. T-lymphocyte development in scid mice is arrested shortly after the initiation of T-cell receptor δ gene recombination. Genes Dev. 5:1357
    • (1991) Genes Dev. , vol.5 , pp. 1357
    • Carroll, A.1    Bosma, M.J.2
  • 6
    • 0027288495 scopus 로고
    • Biased T-cell receptor δ element recombination in scid thymocytes
    • Carroll, A. M., Slack, J. K. and Chang, W.-T. 1993. Biased T-cell receptor δ element recombination in scid thymocytes. Mol. Cell. Biol. 13:3632.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3632
    • Carroll, A.M.1    Slack, J.K.2    Chang, W.-T.3
  • 7
    • 0025811882 scopus 로고
    • The scid mouse mutant: Definition, characterization, and potential uses
    • Bosma, M. J. and Carroll, A.M. 1991. The scid mouse mutant: definition, characterization, and potential uses. Annu. Rev. Immunol. 9:323.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 323
    • Bosma, M.J.1    Carroll, A.M.2
  • 8
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
    • Hardy, R. R., Carmack, C. E., Shinton, S. A., Kemp, J. D. and Hayakawa, K. 1991. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173:1213.
    • (1991) J. Exp. Med. , vol.173 , pp. 1213
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Hayakawa, K.5
  • 9
    • 0027476466 scopus 로고
    • Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development
    • Ehlich, A., Schaal, S., Gu, H., Kitamura, D., Muller W. and Rajewsky, K. 1993. Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development. Cell 72:695.
    • (1993) Cell , vol.72 , pp. 695
    • Ehlich, A.1    Schaal, S.2    Gu, H.3    Kitamura, D.4    Muller, W.5    Rajewsky, K.6
  • 10
    • 0021714531 scopus 로고
    • Introduction of a μ immunoglobulin gene into the mouse germ line: Specific expression in lymphoid cells and synthesis of functional antibody
    • Grosschedl, R., Weaver, D., Baltimore, D. and Costantini, F. 1984. Introduction of a μ immunoglobulin gene into the mouse germ line: specific expression in lymphoid cells and synthesis of functional antibody. Cell 38:647
    • (1984) Cell , vol.38 , pp. 647
    • Grosschedl, R.1    Weaver, D.2    Baltimore, D.3    Costantini, F.4
  • 11
    • 0025980973 scopus 로고
    • Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice
    • Erikson, J., Radic, M. Z., Camper, S. A., Hardy, R. R., Carmack, C. and Weigert, M. 1991. Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature 349:331.
    • (1991) Nature , vol.349 , pp. 331
    • Erikson, J.1    Radic, M.Z.2    Camper, S.A.3    Hardy, R.R.4    Carmack, C.5    Weigert, M.6
  • 12
    • 0022385230 scopus 로고
    • A transgenic immunoglobulin mu gene prevents rearrangement of endogenous genes
    • Weaver, D., Costantini, F., Imanishi-Kari, T. and Baltimore, D. 1985. A transgenic immunoglobulin mu gene prevents rearrangement of endogenous genes. Cell 42:117.
    • (1985) Cell , vol.42 , pp. 117
    • Weaver, D.1    Costantini, F.2    Imanishi-Kari, T.3    Baltimore, D.4
  • 13
    • 0025355883 scopus 로고
    • Development of B-lineage cells in the bone marrow of scid/ scid mice following the introduction of functionally rearranged transgenes
    • Reichman-Fried, M., Hardy, R. R. and Bosma, M. J. 1990. Development of B-lineage cells in the bone marrow of scid/ scid mice following the introduction of functionally rearranged transgenes. Proc. Natl Acad. Sci. USA 87:2730.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 2730
    • Reichman-Fried, M.1    Hardy, R.R.2    Bosma, M.J.3
  • 14
    • 0028979706 scopus 로고
    • Development of B cells in scid mice with immunoglobulin transgenes: Implications for the control of V(D)J recombination
    • Chang, Y., Bosma, G. C. and Bosma, M. J. 1995. Development of B cells in scid mice with immunoglobulin transgenes: implications for the control of V(D)J recombination. Immunity 2:607.
    • (1995) Immunity , vol.2 , pp. 607
    • Chang, Y.1    Bosma, G.C.2    Bosma, M.J.3
  • 15
    • 0026001262 scopus 로고
    • κ8 L chain transgene on endogenous rearrangements and the immune response to the HA(SB) determinant on influenza virus
    • κ8 L chain transgene on endogenous rearrangements and the immune response to the HA(SB) determinant on influenza virus. J. Immunol. 147:2024.
    • (1991) J. Immunol. , vol.147 , pp. 2024
    • Carmack, C.E.1    Camper, S.A.2    Mackle, J.J.3    Gerhard, W.U.4    Weigert, M.G.5
  • 16
    • 0024846088 scopus 로고
    • The V(D)J recombination activating gene, RAG-1
    • Schatz, D, G., Oettinger, M. A. and Baltimore, D. 1989. The V(D)J recombination activating gene, RAG-1. Cell 59:1035.
    • (1989) Cell , vol.59 , pp. 1035
    • Schatz, D.G.1    Oettinger, M.A.2    Baltimore, D.3
  • 17
    • 0025301095 scopus 로고
    • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
    • Oettinger, M. A., Schatz, D. G., Gorka, C. and Baltimore, D. 1990. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science 248:1517.
    • (1990) Science , vol.248 , pp. 1517
    • Oettinger, M.A.1    Schatz, D.G.2    Gorka, C.3    Baltimore, D.4
  • 18
    • 0025011134 scopus 로고
    • The scid mutation in mice causes a general defect in DNA repair
    • Fulop, G. M. and Phillips, R.A. 1990. The scid mutation in mice causes a general defect in DNA repair. Nature 347:479.
    • (1990) Nature , vol.347 , pp. 479
    • Fulop, G.M.1    Phillips, R.A.2
  • 20
    • 0026071588 scopus 로고
    • Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair
    • Biedermann, K. A., Sun, J., Giaccia, A. J., Tosto, L. M. and Brown, M. 1991. Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc. Natl Acad. Sci. USA 88:1394.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 1394
    • Biedermann, K.A.1    Sun, J.2    Giaccia, A.J.3    Tosto, L.M.4    Brown, M.5
  • 21
    • 0028801363 scopus 로고
    • Formation and resolution of double-strand break intermediates in V(D)J rearrangement
    • Ramsden, D. A. and Gellert, M. 1995. Formation and resolution of double-strand break intermediates in V(D)J rearrangement. Genes Dev. 9:2409.
    • (1995) Genes Dev. , vol.9 , pp. 2409
    • Ramsden, D.A.1    Gellert, M.2
  • 22
    • 0021993025 scopus 로고
    • Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line
    • Rusconi, S. and Kohler, G. 1985. Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line. Nature 314:330.
    • (1985) Nature , vol.314 , pp. 330
    • Rusconi, S.1    Kohler, G.2
  • 24
    • 0024384379 scopus 로고
    • Alteration of the B cell surface phenotype, immune response to phosphocholin and the B cell repertoire in M167 μ plus κ transgenic mice
    • Kenny, J. J., Finkelman, F., Macchiarini, F., Kopp, W C., Storb, U. and Longo, D. 1989. Alteration of the B cell surface phenotype, immune response to phosphocholin and the B cell repertoire in M167 μ plus κ transgenic mice. J. Immunol. 142:4466.
    • (1989) J. Immunol. , vol.142 , pp. 4466
    • Kenny, J.J.1    Finkelman, F.2    Macchiarini, F.3    Kopp, W.C.4    Storb, U.5    Longo, D.6
  • 26
    • 0028980776 scopus 로고
    • Stimulation by T cell independent antigens can relieve the arrest of differentiation of immature auto-reactive B cells in the bone marrow
    • Andersson, J., Melchers, F. and Rolink, A. 1995. Stimulation by T cell independent antigens can relieve the arrest of differentiation of immature auto-reactive B cells in the bone marrow. Scand. J. Immunol. 42:21.
    • (1995) Scand. J. Immunol. , vol.42 , pp. 21
    • Andersson, J.1    Melchers, F.2    Rolink, A.3
  • 27
    • 0025877711 scopus 로고
    • Receptor-mediated elimination of phosphocholine-specific B cells in X-linked immunedeficient mice
    • Kenny, J. J., Stall, A. M., Sieckmann, D. G., Lamers, M. C., Finkelman, F. D., Finch, L. and Longo, D. 1991. Receptor-mediated elimination of phosphocholine-specific B cells in X-linked immunedeficient mice. J. Immunol. 146:2568.
    • (1991) J. Immunol. , vol.146 , pp. 2568
    • Kenny, J.J.1    Stall, A.M.2    Sieckmann, D.G.3    Lamers, M.C.4    Finkelman, F.D.5    Finch, L.6    Longo, D.7
  • 28
    • 0026099269 scopus 로고
    • Evidence for regulation of naturally activated autoreactive B cells
    • Zoller, M. and Achtnich, M. 1991. Evidence for regulation of naturally activated autoreactive B cells. Eur. J. Immunol. 21:305.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 305
    • Zoller, M.1    Achtnich, M.2
  • 29
    • 0009927162 scopus 로고
    • Clonal deletion of autoreative B lymphocytes in bone marrow chimeras
    • Nemazee, D. A. and Burki, K. 1989. Clonal deletion of autoreative B lymphocytes in bone marrow chimeras. Proc. Natl Acad. Sci. USA 86:8039.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 8039
    • Nemazee, D.A.1    Burki, K.2
  • 30
    • 0024529870 scopus 로고
    • Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
    • Nemazee, D. A. and Burki, K. 1989. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature 337:562.
    • (1989) Nature , vol.337 , pp. 562
    • Nemazee, D.A.1    Burki, K.2
  • 31
    • 0025948793 scopus 로고
    • Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
    • Hartley, S. B., Crosbie, J., Brink, R., Kantor, A. B., Basten, A. and Goodnow, C. C. 1991. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature 353:765.
    • (1991) Nature , vol.353 , pp. 765
    • Hartley, S.B.1    Crosbie, J.2    Brink, R.3    Kantor, A.B.4    Basten, A.5    Goodnow, C.C.6
  • 32
    • 0027447188 scopus 로고
    • Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
    • Hartley, S. B., Cooke, M. P., Fulcher, D. A., Harris, A. W., Cory, S., Basten, A. and Goodnow, C. 1993. Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death. Cell 72:325.
    • (1993) Cell , vol.72 , pp. 325
    • Hartley, S.B.1    Cooke, M.P.2    Fulcher, D.A.3    Harris, A.W.4    Cory, S.5    Basten, A.6    Goodnow, C.7
  • 33
    • 0025887497 scopus 로고
    • B cell tolerance in mice transgenic for anti-CD8 immunoglobulin mu chain
    • Brombacher, F., Kohler, G. and Eibel, H. 1991. B cell tolerance in mice transgenic for anti-CD8 immunoglobulin mu chain. J. Exp. Med. 174:1335.
    • (1991) J. Exp. Med. , vol.174 , pp. 1335
    • Brombacher, F.1    Kohler, G.2    Eibel, H.3
  • 37
    • 0027538326 scopus 로고
    • B-lineage cells in μ-transgenic scid mice proliferate in response to IL-7 but fail to show evidence of immunoglobulin light chain gene rearrangement
    • Reichman-Fried, M., Bosma, M. J. and Hardy, R. R. 1993. B-lineage cells in μ-transgenic scid mice proliferate in response to IL-7 but fail to show evidence of immunoglobulin light chain gene rearrangement. Int. Immunol. 5:303.
    • (1993) Int. Immunol. , vol.5 , pp. 303
    • Reichman-Fried, M.1    Bosma, M.J.2    Hardy, R.R.3
  • 39
    • 0024431684 scopus 로고
    • In vivo footprinting of a muscle specific enhancer by ligation mediated PCR
    • Mueller, P. R. and Wold, B. 1989. In vivo footprinting of a muscle specific enhancer by ligation mediated PCR. Science 246:780.
    • (1989) Science , vol.246 , pp. 780
    • Mueller, P.R.1    Wold, B.2
  • 40
    • 0027491330 scopus 로고
    • Characterization of broken DNA molecules associated with V(D)J recombination
    • Roth, D. B., Zhu, C. and Gellert, M. 1993. Characterization of broken DNA molecules associated with V(D)J recombination. Proc. Natl Acad. Sci. USA 90:10788
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 10788
    • Roth, D.B.1    Zhu, C.2    Gellert, M.3
  • 41
    • 0024435908 scopus 로고
    • Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription
    • Schlissel, M. S. and Baltimore, D. 1989. Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription. Cell 58:1001.
    • (1989) Cell , vol.58 , pp. 1001
    • Schlissel, M.S.1    Baltimore, D.2
  • 42
    • 0019494043 scopus 로고
    • Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression
    • Coleclough, C., Perry, R. P., Karjalainen, K. and Weigert, M. 1981. Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression. Nature 290:372.
    • (1981) Nature , vol.290 , pp. 372
    • Coleclough, C.1    Perry, R.P.2    Karjalainen, K.3    Weigert, M.4
  • 43
    • 0019211069 scopus 로고
    • 5′ flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains
    • Marcu, K. B., Banerji, J., Penncavage, N. A., Lang, R. and Arnheim, N. 1980. 5′ flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains. Cell 22:187.
    • (1980) Cell , vol.22 , pp. 187
    • Marcu, K.B.1    Banerji, J.2    Penncavage, N.A.3    Lang, R.4    Arnheim, N.5
  • 45
    • 0027478391 scopus 로고
    • Receptor editing in self-reactive bone marrow B cells
    • Tiegs, S. L., Russell, D. M. and Nemazee, D. 1993. Receptor editing in self-reactive bone marrow B cells. J. Exp. Med. 177:1009.
    • (1993) J. Exp. Med. , vol.177 , pp. 1009
    • Tiegs, S.L.1    Russell, D.M.2    Nemazee, D.3
  • 46
    • 0027499537 scopus 로고
    • Receptor editing: An approach by autoreactive B cells to escape tolerance
    • Gay, D., Saunders, T., Camper, S. and Weigert, M. 1993. Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177:999.
    • (1993) J. Exp. Med. , vol.177 , pp. 999
    • Gay, D.1    Saunders, T.2    Camper, S.3    Weigert, M.4
  • 47
    • 0027532192 scopus 로고
    • B lymphocytes may escape tolerance by revising their receptors
    • Radic, M. Z., Erickson, J., Litwin, S. and Weigert, M. 1993. B lymphocytes may escape tolerance by revising their receptors. J. Exp. Med. 177:1165.
    • (1993) J. Exp. Med. , vol.177 , pp. 1165
    • Radic, M.Z.1    Erickson, J.2    Litwin, S.3    Weigert, M.4
  • 49
    • 0025173794 scopus 로고
    • Corrective recombination of mouse immunoglobulin kappa alleles in Abelson murine leukemia virus-transformed pre-B cells
    • Fedderson, R. M. and Van Ness, B. G. 1990. Corrective recombination of mouse immunoglobulin kappa alleles in Abelson murine leukemia virus-transformed pre-B cells. Mol. Cell. Biol. 10:569.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 569
    • Fedderson, R.M.1    Van Ness, B.G.2
  • 50
    • 0026016422 scopus 로고
    • κ gene rearrangement by productively rearranged alleles
    • κ gene rearrangement by productively rearranged alleles. J. Exp. Med. 173:409.
    • (1991) J. Exp. Med. , vol.173 , pp. 409
    • Harada, K.1    Yamagishi, H.2
  • 51
    • 0022773519 scopus 로고
    • H replacement during pre-B differentiation: Non-random usage of gene segments
    • H replacement during pre-B differentiation: non-random usage of gene segments. EMBO J. 5:2131.
    • (1986) EMBO J. , vol.5 , pp. 2131
    • Reth, M.G.1    Jackson, S.2    Alt, F.W.3
  • 54
    • 0029557123 scopus 로고
    • Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin κ locus
    • George, J. B. and Garrard, W. T. 1995. Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin κ locus. Proc. Natl Acad. Sci. USA 92:12421.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 12421
    • George, J.B.1    Garrard, W.T.2
  • 55
    • 0020041687 scopus 로고
    • Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments
    • Kurosawa, Y. and Tonegawa, S. 1982. Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments. J. Exp. Med. 155:201.
    • (1982) J. Exp. Med. , vol.155 , pp. 201
    • Kurosawa, Y.1    Tonegawa, S.2
  • 58
    • 0022565521 scopus 로고
    • Regulation of the assembly and expression of variable-region genes
    • Yancopoulos, D. and Alt, F. 1986. Regulation of the assembly and expression of variable-region genes. Annu. Rev. Immunol. 4:339.
    • (1986) Annu. Rev. Immunol. , vol.4 , pp. 339
    • Yancopoulos, D.1    Alt, F.2
  • 59
    • 0023068159 scopus 로고
    • Transgenic mice with immunoglobulin genes
    • Storb, U. 1987. Transgenic mice with immunoglobulin genes. Ann. Rev. Immunol. 5:151.
    • (1987) Ann. Rev. Immunol. , vol.5 , pp. 151
    • Storb, U.1
  • 61
    • 0029776886 scopus 로고    scopus 로고
    • Early expression of Ig μ chain from a transgene significantly reduces the duration of the pro-B stage but does not affect the small pre-B stage
    • Arakawa, H. and Takeda, S. 1996. Early expression of Ig μ chain from a transgene significantly reduces the duration of the pro-B stage but does not affect the small pre-B stage. Int. Immunol. 8:1319.
    • (1996) Int. Immunol. , vol.8 , pp. 1319
    • Arakawa, H.1    Takeda, S.2


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