Probing the structure of the HIV-1 Rev trans-activator protein by functional analysis

Protein Engineering

Volumn 10, Issue 2, 1997, Pages 103-107

  Thomas, Sarah L ^a   Hauber, Joachim ^a   Casari, Georg ^b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

HIV 1 Rev; Mutagenesis; Protein structure; Structure determination

Indexed keywords

REV PROTEIN; TRANSACTIVATOR PROTEIN; VIRUS PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0031047864     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/10.2.103     Document Type: Article

References (37)

1. Auer, M., Gremlich, H.-U., Seifer, J.-M., Daly, T.J., Parslow, J.G., Casari, G. and Gstach, H. (1994) Biochemistry, 33, 2988-2996.
2. Berger, J., Aepinus, C., Dobrovnik, M., Fleckenstein, B., Hauber, J. and Böhnlein, E. (1991) Virology, 183, 630-635.
3. Bevec, D. et al. (1996) Science, 271, 1858-1860.
4. Bogerd, H.P., Fridell, R.A., Madore, S. and Cullen, B.R. (1995) Cell, 82, 485-494.
5. Böhnlein, E., Berger, J. and Hauber, J. (1991) J. Virol., 65, 7051-7055.
6. Buckle, A.M., Henrick, K. and Fersht, A.R. (1993) J. Mol. Biol., 234, 847-860.
7. Cullen, B.R. (1986a) Cell, 46, 973-982.
8. Cullen, B.R.(1986b) Methods Enzymol., 152, 684-704.
9. Cullen, B.R. (1991) Annu. Rev. Microbiol., 45, 219-250.
10. Cullen, B.R. and Malim, M.H. (1991) Trends Biochem. Sci., 16, 346-350.
11. Eriksson, A.E., Baase, W.A., Zhang, X.J., Heinz, D.W., Blaber, M., Baldwin, E.P. and Matthews, B.W. (1992) Science, 255, 178-183.
12. Fiering, S.N., Roederer, M., Nolan, G.P., Micklem, D.R., Parks, D.R. and Herzenberg, L.A. (1991) Cytometry, 12, 291-301.
13. Fritz, C.C., Zapp, M.L. and Green, M.R. (1995) Nature, 376, 530-533.
14. Gerace, L. (1995) Cell, 82, 341-344.
15. Goebel, U., Sander, C., Schneider, R. and Valencia, A. (1994) Proteins: Struct. Funct. Genet., 18, 309-317.
16. Greene, W.C. (1991) N. Engl. J. Med., 324, 308-324.
17. Gregoret, L.M. and Sauer, R.T. (1993) Proc. Natl Acad. Sci. USA, 90, 4246-4250.
18. Hammerschmid, M., Palmeri, D., Ruhl, M., Jaksche, H., Weichselbraun, I., Böhnlein, E., Malim, M.H. and Hauber, J. (1994) J. Virol., 68, 7329-7335.
19. Hope, T.J., Huang, X., McDonald, D. and Parslow, T.G. (1990a) Proc. Natl Acad. Sci. USA, 87, 7787-7791.
20. Hope, T.J., McDonald, D., Huang, X., Low, J. and Parslow, J.G. (1990b) J. Virol., 64, 5360-5366.
21. Hope, T.J., Bond, B.L., McDonald, D., Klein, N.P. and Parslow, T.G. (1991) J. Virol., 65, 6001-6007.
22. Jackson, S.E., Moracci, M., elMasry, N., Johnson, C.M. and Fersht, A.R. (1993) Biochemistry, 32, 11259-11269.
23. Kjems, J., Calnan, B.J., Frankel, A.D. and Sharp, P.A. (1992) EMBO J., 11, 1119-1129.
24. Malim, M.H. and Cullen, B.R. (1991) Cell, 65, 241-248.
25. Malim, M.H., Hauber, J., Fenrick, R. and Cullen, B.R. (1988) Nature, 335, 181-183.
26. Malim, M.H., Böhnlein, S., Hauber, J. and Cullen, B.R. (1989) Cell, 58, 205-214.
27. Malim, M.H., McCarn, D.F., Tiley, L.S. and Cullen, B.R. (1991) J. Virol., 65, 4248-4254.
28. Mermer, B., Felber, B.K., Campbell, M. and Pavlakis, G.N. (1990) Nucleic Acids Res., 18, 2037-2044.
29. Neher, E. (1994) Proc. Natl Acad. Sci. USA, 91, 98-102.
30. Olsen, H.S., Cochrane, A.W., Dillon, P.J., Nalin, C.M. and Rosen, C.A. (1990) Genes Dev., 4, 1357-1364.
31. Pavlakis, G.N. and Felber, B.K. (1990) Nature New Biol., 2, 20-31.
32. Ruhl, M., et al. (1993) J. Cell Biol., 123, 1309-1320.
33. Venkatesh, L.K. and Chinnadurai, G. (1990) Virology, 178, 327-330.
34. Weichselbraun, I., Berger, J., Dobrovnik, M., Bogerd, H., Grassmann, R., Greene, W.C., Hauber, J. and Böhnlein, E. (1992a) J. Virol., 66, 4540-4545.
35. Weichselbraun, I., Farrington, G.K., Rusche, J.R., Böhnlein, E. and Hauber, J. (1992b) J. Virol., 66, 2583-2587.
36. Wells, J.A. (1990) Biochemistry, 29, 8509-8517.
37. Zapp, M.L., Hope, T.J., Parslow, J.G. and Green, M.R. (1991) Proc. Natl Acad. Sci. USA, 88, 7734-7738.