-
1
-
-
0025049031
-
Immunologic abnormalities in pathogen-free cats experimentally infected with feline immunodeficiency virus
-
Ackley, C. D., J. K. Yamamoto, N. Levy, N. C. Pedersen, and M. D. Cooper. 1990. Immunologic abnormalities in pathogen-free cats experimentally infected with feline immunodeficiency virus. J. Virol. 64:5652-5655.
-
(1990)
J. Virol.
, vol.64
, pp. 5652-5655
-
-
Ackley, C.D.1
Yamamoto, J.K.2
Levy, N.3
Pedersen, N.C.4
Cooper, M.D.5
-
2
-
-
0025084615
-
HIV-1 reverse transcriptase: Structural predictions for the polymerase domain
-
Barber, A. M., A. Hizi, J. V. Maizel, and S. H. Hughes. 1990. HIV-1 reverse transcriptase: structural predictions for the polymerase domain. AIDS Res. Hum. Retroviruses 6:1061-1072.
-
(1990)
AIDS Res. Hum. Retroviruses
, vol.6
, pp. 1061-1072
-
-
Barber, A.M.1
Hizi, A.2
Maizel, J.V.3
Hughes, S.H.4
-
3
-
-
0026029861
-
Acquired immune dysfunction in cats with experimentally induced feline immunodeficiency virus infection: Comparison of short-term and long-term infections
-
Barlough, J. E., C. D. Ackley, J. W. George, N. Levy, R. Acevedo, P. F. Moore, B. A. Rideout, M. D. Cooper, and N. C. Pedersen. 1991. Acquired immune dysfunction in cats with experimentally induced feline immunodeficiency virus infection: comparison of short-term and long-term infections. J. Acquired Immune Defic. Syndr. 4:219-227.
-
(1991)
J. Acquired Immune Defic. Syndr.
, vol.4
, pp. 219-227
-
-
Barlough, J.E.1
Ackley, C.D.2
George, J.W.3
Levy, N.4
Acevedo, R.5
Moore, P.F.6
Rideout, B.A.7
Cooper, M.D.8
Pedersen, N.C.9
-
4
-
-
0026534342
-
Synthesis of enantiomerically pure (2′R,5′S)-(-)-1-[2-(hydroxymethyl)-oxathiolan-5-yl] cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)
-
Beach, J. W., L. S. Jeong, A. J. Alves, D. Pohl, H. O. Kim, C.-N. Chang, S.-L. Doong, R. F. Schinazi, Y.-C. Cheng, and C. K. Chu. 1992. Synthesis of enantiomerically pure (2′R,5′S)-(-)-1-[2-(hydroxymethyl)-oxathiolan-5-yl] cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV). J. Org. Chem. 57:2217-2219.
-
(1992)
J. Org. Chem.
, vol.57
, pp. 2217-2219
-
-
Beach, J.W.1
Jeong, L.S.2
Alves, A.J.3
Pohl, D.4
Kim, H.O.5
Chang, C.-N.6
Doong, S.-L.7
Schinazi, R.F.8
Cheng, Y.-C.9
Chu, C.K.10
-
5
-
-
0027373308
-
High-level resistance to (-) enantiomeric 2′-deoxy-3′-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase
-
Boucher, C. A. B., N. Cammack, P. Schipper, R. Schuurman, P. Rouse, M. A. Wainberg, and J. M. Cameron. 1993. High-level resistance to (-) enantiomeric 2′-deoxy-3′-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase. Antimicrob. Agents Chemother. 37:2231-2234.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 2231-2234
-
-
Boucher, C.A.B.1
Cammack, N.2
Schipper, P.3
Schuurman, R.4
Rouse, P.5
Wainberg, M.A.6
Cameron, J.M.7
-
6
-
-
0026500566
-
Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1
-
Boyer, P. L., A. L. Ferris, and S. H. Hughes. 1992. Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1. J. Virol. 66:1745-1755.
-
(1992)
J. Virol.
, vol.66
, pp. 1745-1755
-
-
Boyer, P.L.1
Ferris, A.L.2
Hughes, S.H.3
-
7
-
-
12044254762
-
In situ complexation directs the stereochemistry of N-glycosylation in the synthesis of oxathiolanyl and dioxythiolanyl nucleoside analogs
-
Choi, C. K., J. W. Beach, L. J. Wilson, S. Yeola, D. C. Liotta, and R. F. Schinazi. 1991. In situ complexation directs the stereochemistry of N-glycosylation in the synthesis of oxathiolanyl and dioxythiolanyl nucleoside analogs. J. Am. Chem. Soc. 113:9377-9379.
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 9377-9379
-
-
Choi, C.K.1
Beach, J.W.2
Wilson, L.J.3
Yeola, S.4
Liotta, D.C.5
Schinazi, R.F.6
-
8
-
-
0026507919
-
(-)-2′-Deoxy-3′-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro
-
Coates, J. A. V., N. Cammack, H. J. Jenkinson, A. J. Jowett, M. I. Jowett, B. A. Pearson, C. R. Penn, P. L. Rouse, K. C. Viner, and J. M. Cameron. 1992. (-)-2′-Deoxy-3′-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro. Antimicrob. Agents Chemother. 36:733-739.
-
(1992)
Antimicrob. Agents Chemother.
, vol.36
, pp. 733-739
-
-
Coates, J.A.V.1
Cammack, N.2
Jenkinson, H.J.3
Jowett, A.J.4
Jowett, M.I.5
Pearson, B.A.6
Penn, C.R.7
Rouse, P.L.8
Viner, K.C.9
Cameron, J.M.10
-
9
-
-
0028943992
-
In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
-
Condra, J. H., W. A. Schieif, O. M. Blahy, L. J. Gabryelski, D. J. Graham, J. C. Quintero, A. Rhodes, H. L. Robbins, E. Roth, M. Shivaprakash, D. Titus, T. Yang, H. Teppler, K. E. Squires, P. J. Deutsch, and E. A. Emini. 1995. In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Nature (London) 374:569-571.
-
(1995)
Nature (London)
, vol.374
, pp. 569-571
-
-
Condra, J.H.1
Schieif, W.A.2
Blahy, O.M.3
Gabryelski, L.J.4
Graham, D.J.5
Quintero, J.C.6
Rhodes, A.7
Robbins, H.L.8
Roth, E.9
Shivaprakash, M.10
Titus, D.11
Yang, T.12
Teppler, H.13
Squires, K.E.14
Deutsch, P.J.15
Emini, E.A.16
-
10
-
-
0026806042
-
Inhibition of reverse transcriptase from feline immunodeficiency virus by analogs of 2′-deoxyadenosine-5′-triphosphate
-
Cronn, R. C., K. M. Remington, B. D. Preston, and T. W. North. 1992. Inhibition of reverse transcriptase from feline immunodeficiency virus by analogs of 2′-deoxyadenosine-5′-triphosphate. Biochem. Pharmacol. 44:1375-1381.
-
(1992)
Biochem. Pharmacol.
, vol.44
, pp. 1375-1381
-
-
Cronn, R.C.1
Remington, K.M.2
Preston, B.D.3
North, T.W.4
-
11
-
-
0026523623
-
HIV inhibitors targeted at the reverse transcriptase
-
DeClercq, E. 1992. HIV inhibitors targeted at the reverse transcriptase. AIDS Res. Hum. Retroviruses 8:119-134.
-
(1992)
AIDS Res. Hum. Retroviruses
, vol.8
, pp. 119-134
-
-
DeClercq, E.1
-
12
-
-
0027964486
-
Development of clinical disease in cats experimentally infected with feline immunodeficiency virus
-
English, R. V., P. Nelson, C. M. Johnson, M. Nasisse, W. A. Tompkins, and M. B. Tompkins. 1994. Development of clinical disease in cats experimentally infected with feline immunodeficiency virus. J. Infect. Dis. 170:543-552.
-
(1994)
J. Infect. Dis.
, vol.170
, pp. 543-552
-
-
English, R.V.1
Nelson, P.2
Johnson, C.M.3
Nasisse, M.4
Tompkins, W.A.5
Tompkins, M.B.6
-
13
-
-
0028021844
-
Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5′-triphosphate β enantiomers of cytidine analogs
-
Faraj, A., L. A. Agrofoglio, J. K. Wakefield, S. McPherson, C. D. Morrow, G. Gosselin, C. Mathe, J.-L. Imbach, R. F. Schinazi, and J.-P. Sommadossi. 1994. Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5′-triphosphate β enantiomers of cytidine analogs. Antimicrob. Agents Chemother. 38:2300-2305.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 2300-2305
-
-
Faraj, A.1
Agrofoglio, L.A.2
Wakefield, J.K.3
McPherson, S.4
Morrow, C.D.5
Gosselin, G.6
Mathe, C.7
Imbach, J.-L.8
Schinazi, R.F.9
Sommadossi, J.-P.10
-
14
-
-
1842269090
-
Selective inhibition of viral DNA polymerases by the triphosphate of β-L-2′,3′-dideoxycytidine (β-L-DDC) and its 5-fluoro derivative (β-L- FDDC)
-
Faraj, A., G. Gosselin, J.-L. Imbach, R. F. Schinazi, and J.-P. Sommadossi. 1994. Selective inhibition of viral DNA polymerases by the triphosphate of β-L-2′,3′-dideoxycytidine (β-L-DDC) and its 5-fluoro derivative (β-L-FDDC). Antiviral Res. 23(Suppl. 1):53.
-
(1994)
Antiviral Res.
, vol.23
, Issue.1 SUPPL.
, pp. 53
-
-
Faraj, A.1
Gosselin, G.2
Imbach, J.-L.3
Schinazi, R.F.4
Sommadossi, J.-P.5
-
15
-
-
0026529145
-
Human immunodeficiency virus type 1 pol gene mutations which cause decreased susceptibility to 2′,3′-dideoxycytidine
-
Fitzgibbon, J. E., R. M. Howell, C. A. Haberzettl, S. J. Sperber, D. J. Gocke, and D. T. Dubin. 1992. Human immunodeficiency virus type 1 pol gene mutations which cause decreased susceptibility to 2′,3′-dideoxycytidine. An timicrob. Agents Chemother. 36:153-157.
-
(1992)
An Timicrob. Agents Chemother.
, vol.36
, pp. 153-157
-
-
Fitzgibbon, J.E.1
Howell, R.M.2
Haberzettl, C.A.3
Sperber, S.J.4
Gocke, D.J.5
Dubin, D.T.6
-
16
-
-
0027506940
-
Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2′,3′-dideoxycytidine and 2′,3′- Dideoxy-3′-thiacytidine
-
Gao, Q., Z. Gu, J. Hiscott, G. Dionne, and M. A. Wainberg. 1993. Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2′,3′-dideoxycytidine and 2′,3′-dideoxy-3′-thiacytidine. Antimicrob. Agents Chemother. 37:130-133.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 130-133
-
-
Gao, Q.1
Gu, Z.2
Hiscott, J.3
Dionne, G.4
Wainberg, M.A.5
-
17
-
-
0027155374
-
The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2′,3′-dideoxyinosine and 2′,3′- Dideoxycytidine confers high-level resistance to the (-) enantiomer of 2′,3′- dideoxy-3′-thiacytidine
-
Gao, Q., Z. Gu, M. A. Parniak, J. Cameron, N. Cammack, C. Boucher, and M. A. Wainberg. 1993. The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2′,3′-dideoxyinosine and 2′,3′-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2′,3′-dideoxy-3′-thiacytidine. Antimicrob. Agents Chemother. 37:1390-1392.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 1390-1392
-
-
Gao, Q.1
Gu, Z.2
Parniak, M.A.3
Cameron, J.4
Cammack, N.5
Boucher, C.6
Wainberg, M.A.7
-
18
-
-
0026542755
-
In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine
-
Gao, Q., Z. Gu, M. A. Parniak, X. Li, and M. A. Wainberg. 1992. In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine. J. Virol. 66:12-19.
-
(1992)
J. Virol.
, vol.66
, pp. 12-19
-
-
Gao, Q.1
Gu, Z.2
Parniak, M.A.3
Li, X.4
Wainberg, M.A.5
-
19
-
-
0028209173
-
Multiple- Drug-resistant mutants of feline immunodeficiency virus selected with 2′,3′- dideoxyinosine alone and in combination with 3′-azido-3′-deoxythymidine
-
Gobert, J. M., K. M. Remington, Y.-Q. Zhu, and T. W. North. 1994. Multiple-drug-resistant mutants of feline immunodeficiency virus selected with 2′,3′-dideoxyinosine alone and in combination with 3′-azido-3′-deoxythymidine. Antimicrob. Agents Chemother. 38:861-864.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 861-864
-
-
Gobert, J.M.1
Remington, K.M.2
Zhu, Y.-Q.3
North, T.W.4
-
20
-
-
0028230923
-
Anti-human immunodeficiency virus activities of the β-L-enantiomer of 2′,3′-dideoxycytidine and its 5-fluoro derivative in vitro
-
Gosselin, G., R. F. Schinazi, J.-P. Sommadossi, C. Mathé, M.-C. Bergogne, A.-M. Aubertin, A. Kirn, and J.-L. Imbach. 1994. Anti-human immunodeficiency virus activities of the β-L-enantiomer of 2′,3′-dideoxycytidine and its 5-fluoro derivative in vitro. Antimicrob. Agents Chemother. 38:1292-1297.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 1292-1297
-
-
Gosselin, G.1
Schinazi, R.F.2
Sommadossi, J.-P.3
Mathé, C.4
Bergogne, M.-C.5
Aubertin, A.-M.6
Kirn, A.7
Imbach, J.-L.8
-
21
-
-
0028057581
-
Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficieney virus resistance to 2′,3′-dideoxycytidine and 2′,3′-dideoxy-3′- Thiacytidine
-
Gu, Z., Q. Gao, H. Fang, H. Salomon, M. A. Parniak, E. Goldberg, J. Cameron, and M. A. Wainberg. 1994. Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficieney virus resistance to 2′,3′-dideoxycytidine and 2′,3′-dideoxy-3′-thiacytidine. Antimicrob. Agents Chemother. 38:275-281.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 275-281
-
-
Gu, Z.1
Gao, Q.2
Fang, H.3
Salomon, H.4
Parniak, M.A.5
Goldberg, E.6
Cameron, J.7
Wainberg, M.A.8
-
22
-
-
0026483089
-
Enzyme-mediated enantioselective preparation of pure enantiomers of the antiviral agent 2′,3′-dideoxy-5-fluoro-3′-thiacytidine [(-)-FTC] and related compounds
-
Hoong, L. K., L. E. Strange, D. C. Liotta, G. W. Koszalka, C. L. Burns, and R. F. Schinazi. 1992. Enzyme-mediated enantioselective preparation of pure enantiomers of the antiviral agent 2′,3′-dideoxy-5-fluoro-3′-thiacytidine [(-)-FTC] and related compounds. J. Org. Chem. 57:5563-5585.
-
(1992)
J. Org. Chem.
, vol.57
, pp. 5563-5585
-
-
Hoong, L.K.1
Strange, L.E.2
Liotta, D.C.3
Koszalka, G.W.4
Burns, C.L.5
Schinazi, R.F.6
-
23
-
-
0028843163
-
Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959
-
Jacobsen, H., K. Yasargil, D. L. Winslow, J. C. Craig, A. Krohn, I. B. Duncan, and J. Mous. 1995. Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959. Virology 206:527-534.
-
(1995)
Virology
, vol.206
, pp. 527-534
-
-
Jacobsen, H.1
Yasargil, K.2
Winslow, D.L.3
Craig, J.C.4
Krohn, A.5
Duncan, I.B.6
Mous, J.7
-
24
-
-
0028286025
-
Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease
-
Kaplan, A. H., S. F. Michael, R. S. Wehbie, M. F. Knigge, D. A. Paul, L. Event, D. J. Kempf, D. W. Norbeck, J. W. Erickson, and R. Swanstrom. 1994. Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease. Proc. Natl. Acad. Sci. USA 91:5597-5601.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5597-5601
-
-
Kaplan, A.H.1
Michael, S.F.2
Wehbie, R.S.3
Knigge, M.F.4
Paul, D.A.5
Event, L.6
Kempf, D.J.7
Norbeck, D.W.8
Erickson, J.W.9
Swanstrom, R.10
-
25
-
-
1842318148
-
Initial appearance of 184Ile variant in 3TC-treated patients can be explained by the mutation bias of the HIV-1 RT enzyme
-
in press
-
Keulen, W., A. van Wijk, C. Boucher, and B. Berkhout. Initial appearance of 184Ile variant in 3TC-treated patients can be explained by the mutation bias of the HIV-1 RT enzyme. Antiviral Ther., in press.
-
Antiviral Ther.
-
-
Keulen, W.1
Van Wijk, A.2
Boucher, C.3
Berkhout, B.4
-
27
-
-
0026042638
-
Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture
-
Larder, B. A., K. E. Coates, and S. D. Kemp. 1991. Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture. J. Virol. 65:5232-5236.
-
(1991)
J. Virol.
, vol.65
, pp. 5232-5236
-
-
Larder, B.A.1
Coates, K.E.2
Kemp, S.D.3
-
28
-
-
0024508058
-
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy
-
Larder, B. A., G. Darby, and D. D. Richman. 1989. HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. Science 243:173-1-1734.
-
(1989)
Science
, vol.243
, pp. 1731-1734
-
-
Larder, B.A.1
Darby, G.2
Richman, D.D.3
-
29
-
-
0024310253
-
Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
-
Larder, B. A., and S. D: Kemp. 1989. Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science 246: 1155-1158.
-
(1989)
Science
, vol.246
, pp. 1155-1158
-
-
Larder, B.A.1
Kemp, S.D.2
-
30
-
-
0029028067
-
Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy
-
Larder, B. A., S. D. Kemp, and P. R. Harington. 1995. Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy. Science 269:696-699.
-
(1995)
Science
, vol.269
, pp. 696-699
-
-
Larder, B.A.1
Kemp, S.D.2
Harington, P.R.3
-
31
-
-
0029865203
-
Selection and characterization of a mutant of feline immunodeficiency virus resistant to 2′,3′-dideoxycytidine
-
Medlin, H. K., Y.-Q. Zhu, K. M. Remington, T. R. Phillips, and T. W. North. 1996. Selection and characterization of a mutant of feline immunodeficiency virus resistant to 2′,3′-dideoxycytidine. Antimicrob. Agents Chemother. 40: 953-957.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 953-957
-
-
Medlin, H.K.1
Zhu, Y.-Q.2
Remington, K.M.3
Phillips, T.R.4
North, T.W.5
-
32
-
-
0028855166
-
Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance
-
Mellors, J. W., B. A. Larder, and R. F. Schinazi. 1995. Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance. Int. Antivir. News 3:8-13.
-
(1995)
Int. Antivir. News
, vol.3
, pp. 8-13
-
-
Mellors, J.W.1
Larder, B.A.2
Schinazi, R.F.3
-
33
-
-
0024998733
-
Direct comparisons of inhibitor sensitivities of reverse transcriptases from feline and human immunodeficiency viruses
-
North, T. W., R. C. Cronn, K. M. Remington, and R. T. Tandberg. 1990. Direct comparisons of inhibitor sensitivities of reverse transcriptases from feline and human immunodeficiency viruses. Antimicrob. Agents Chemother. 34:1505-1507.
-
(1990)
Antimicrob. Agents Chemother.
, vol.34
, pp. 1505-1507
-
-
North, T.W.1
Cronn, R.C.2
Remington, K.M.3
Tandberg, R.T.4
-
34
-
-
0025248568
-
Characterization of reverse transcriptase from feline immunodeficiency virus
-
North, T. W., R. C. Cronn, K. M. Remington, R. T. Tandberg, and R. C. Judd. 1990. Characterization of reverse transcriptase from feline immunodeficiency virus. J. Biol. Chem. 265:5121-5128.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 5121-5128
-
-
North, T.W.1
Cronn, R.C.2
Remington, K.M.3
Tandberg, R.T.4
Judd, R.C.5
-
35
-
-
0028123637
-
Expression of reverse transcriptase from feline immunodeficiency virus in Escherichia coli
-
North, T. W., G. L. Hansen, Y.-Q. Zhu, J. A. Griffin, and C.-K. Shih. 1994. Expression of reverse transcriptase from feline immunodeficiency virus in Escherichia coli. Antimicrob. Agents Chemother. 38:388-391.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 388-391
-
-
North, T.W.1
Hansen, G.L.2
Zhu, Y.-Q.3
Griffin, J.A.4
Shih, C.-K.5
-
36
-
-
0029045521
-
Testing HIV-1 drugs in the FIV model
-
North, T. W., and R. A. LaCasse. 1995. Testing HIV-1 drugs in the FIV model. Nat. Med. 1:410-411.
-
(1995)
Nat. Med.
, vol.1
, pp. 410-411
-
-
North, T.W.1
LaCasse, R.A.2
-
37
-
-
0024332802
-
Feline immunodeficiency virus: A model for reverse transcriptase-targeted chemotherapy for acquired immune deficiency syndrome
-
North, T. W., G. L. T. North, and N. C. Pedersen. 1989. Feline immunodeficiency virus: a model for reverse transcriptase-targeted chemotherapy for acquired immune deficiency syndrome. Antimicrob. Agents Chemother. 33: 915-919.
-
(1989)
Antimicrob. Agents Chemother.
, vol.33
, pp. 915-919
-
-
North, T.W.1
North, G.L.T.2
Pedersen, N.C.3
-
38
-
-
0024366204
-
Nucleotide sequence analysis of feline immunodeficiency virus: Genome organization and relationship to other lentiviruses
-
Olmsted, R. A., V. M. Hirsch, R. H. Purcell, and P. R. Johnson. 1989. Nucleotide sequence analysis of feline immunodeficiency virus: genome organization and relationship to other lentiviruses. Proc. Natl. Acad. Sci. USA 86:8088-8092.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 8088-8092
-
-
Olmsted, R.A.1
Hirsch, V.M.2
Purcell, R.H.3
Johnson, P.R.4
-
39
-
-
0027219220
-
In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease
-
Otto, M. J., S. Garber, D. L. Winslow, C. D. Reid, P. Aldrich, P. K. Jadhav, C. E. Pattersen, C. N. Hodge, and Y.-S. E. Cheng. 1993. In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease. Proc. Natl. Acad. Sci. USA 90:7543-7547.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7543-7547
-
-
Otto, M.J.1
Garber, S.2
Winslow, D.L.3
Reid, C.D.4
Aldrich, P.5
Jadhav, P.K.6
Pattersen, C.E.7
Hodge, C.N.8
Cheng, Y.-S.E.9
-
40
-
-
0000539970
-
The feline immunodeficiency virus
-
J. A. Levy (ed.) Plenum Press, New York, N.Y
-
Pedersen, N. C. 1993. The feline immunodeficiency virus, p. 181-219. In J. A. Levy (ed.), The Retroviridae, vol. 2. Plenum Press, New York, N.Y.
-
(1993)
The Retroviridae
, vol.2
, pp. 181-219
-
-
Pedersen, N.C.1
-
41
-
-
0023137671
-
Isolation of a T-lymphotrophic virus from domestic cats with an immunodeficiency- Like syndrome
-
Pedersen, N. C., E. W. Ho, M. L. Brown, and J. K. Yamamoto. 1987. Isolation of a T-lymphotrophic virus from domestic cats with an immunodeficiency-like syndrome. Science 235:790-793.
-
(1987)
Science
, vol.235
, pp. 790-793
-
-
Pedersen, N.C.1
Ho, E.W.2
Brown, M.L.3
Yamamoto, J.K.4
-
42
-
-
0028344145
-
Neurological abnormalities associated with feline immunodeficiency virus infection
-
Phillips, T. R., O. Prospero-Garcia, D. L. Puaoi, D. L. Lerner, H. S. Fox, R. A. Olmsted, F. E. Bloom, S. J. Henriksen, and J. H. Elder. 1994. Neurological abnormalities associated with feline immunodeficiency virus infection. J. Gen. Virol. 75:979-987.
-
(1994)
J. Gen. Virol.
, vol.75
, pp. 979-987
-
-
Phillips, T.R.1
Prospero-Garcia, O.2
Puaoi, D.L.3
Lerner, D.L.4
Fox, H.S.5
Olmsted, R.A.6
Bloom, F.E.7
Henriksen, S.J.8
Elder, J.H.9
-
43
-
-
0028997078
-
A phase I/II study of 2′-deoxy-3′-thiacytidine (lamivudine) in patients with advanced human immunodeficiency virus infection
-
Pluda, J. M., T. P. Cooley, J. S. G. Montaner, L. E. Shay, N. E. Reinhalter, S. N. Warthan, J. Ruedy, H. M. Hirst, C. A. Vicary, J. B. Quinn, G. J. Yuen, W. A. Wainberg, M. Rubin, and R. Yarchoan. 1995. A phase I/II study of 2′-deoxy-3′-thiacytidine (lamivudine) in patients with advanced human immunodeficiency virus infection. J. Infect. Dis. 171:1438-1447.
-
(1995)
J. Infect. Dis.
, vol.171
, pp. 1438-1447
-
-
Pluda, J.M.1
Cooley, T.P.2
Montaner, J.S.G.3
Shay, L.E.4
Reinhalter, N.E.5
Warthan, S.N.6
Ruedy, J.7
Hirst, H.M.8
Vicary, C.A.9
Quinn, J.B.10
Yuen, G.J.11
Wainberg, W.A.12
Rubin, M.13
Yarchoan, R.14
-
44
-
-
0027210361
-
AIDS-associated encephalopathy with experimental feline immunodeficiency virus infection
-
Podel, M. N., M. Oglesbee, L. Mathes, S. Krakowka, R. Olmstead, and L. Lafredo. 1993. AIDS-associated encephalopathy with experimental feline immunodeficiency virus infection. J. Acquired Immune Defic. Syndr. 6:758-771.
-
(1993)
J. Acquired Immune Defic. Syndr.
, vol.6
, pp. 758-771
-
-
Podel, M.N.1
Oglesbee, M.2
Mathes, L.3
Krakowka, S.4
Olmstead, R.5
Lafredo, L.6
-
45
-
-
0026051129
-
Mutants of feline immunodeficiency virus resistant to 3′-azido-3′- Deoxythymidine
-
Remington, K. M., B. Chesebro, K. Wehrly, N. C. Pedersen, and T. W. North. 1991. Mutants of feline immunodeficiency virus resistant to 3′-azido-3′-deoxythymidine. J. Virol. 65:308-312.
-
(1991)
J. Virol.
, vol.65
, pp. 308-312
-
-
Remington, K.M.1
Chesebro, B.2
Wehrly, K.3
Pedersen, N.C.4
North, T.W.5
-
46
-
-
0028012038
-
Rapid phenotypic reversion of zidovudine-resistant feline immunodeficiency virus without loss of drug-resistant reverse transcriptase
-
Remington, K. M., Y.-Q. Zhu, T. R. Phillips, and T. W. North. 1994. Rapid phenotypic reversion of zidovudine-resistant feline immunodeficiency virus without loss of drug-resistant reverse transcriptase. J. Virol. 68:632-637.
-
(1994)
J. Virol.
, vol.68
, pp. 632-637
-
-
Remington, K.M.1
Zhu, Y.-Q.2
Phillips, T.R.3
North, T.W.4
-
47
-
-
0027278781
-
Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents
-
Richman, D. D. 1993. Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents. Antimicrob. Agents Chemother. 37: 1207-1213.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 1207-1213
-
-
Richman, D.D.1
-
48
-
-
0027957791
-
Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy
-
Richman, D. D., D. Havlir, J. Corbeil, D. Looney, C. Ignacio, S. A. Spector, J. Sullivan, S. Cheeseman, K. Barringer, D. Pauletti, C. K. Shih, M. Myers, and J. Griffin. 1994. Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy. J. Virol. 68:1660-1666.
-
(1994)
J. Virol.
, vol.68
, pp. 1660-1666
-
-
Richman, D.D.1
Havlir, D.2
Corbeil, J.3
Looney, D.4
Ignacio, C.5
Spector, S.A.6
Sullivan, J.7
Cheeseman, S.8
Barringer, K.9
Pauletti, D.10
Shih, C.K.11
Myers, M.12
Griffin, J.13
-
49
-
-
0027409698
-
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides
-
Schinazi, R. F., R. M. Lloyd, Jr., M.-H. Nguyen, D. L. Cannon, A. McMillan, N. Ilksoy, C. K. Chu, D. C. Liotta, H. Z. Bazmi, and J. W. Mellors. 1993. Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides. Antimicrob. Agents Chemother. 37:875-881.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 875-881
-
-
Schinazi, R.F.1
Lloyd Jr., R.M.2
Nguyen, M.-H.3
Cannon, D.L.4
McMillan, A.5
Ilksoy, N.6
Chu, C.K.7
Liotta, D.C.8
Bazmi, H.Z.9
Mellors, J.W.10
-
50
-
-
0026480950
-
Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(Hydroxymethyl)- 1,3-oxathiolan-5-yl]cytosine
-
Schinazi, R. F., A. McMillan, D. Cannon, R. Mathis, R. M. Lloyd, A. Peck, J.-P. Sommadossi, M. St. Clair, J. Wilson, P. Furman, G. Painter, W.-B. Choi, and D. Liotta. 1992. Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine. Antimicrob. Agents Chemother. 36:2423-2431.
-
(1992)
Antimicrob. Agents Chemother.
, vol.36
, pp. 2423-2431
-
-
Schinazi, R.F.1
McMillan, A.2
Cannon, D.3
Mathis, R.4
Lloyd, R.M.5
Peck, A.6
Sommadossi, J.-P.7
St. Clair, M.8
Wilson, J.9
Furman, P.10
Painter, G.11
Choi, W.-B.12
Liotta, D.13
-
51
-
-
0029024089
-
Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant populations in persons treated with lamivudine (3TC)
-
Schuurman, R., M. Nijhuis, R. van Leeuen, P. Schipper, D. de Jong, P. Collis, S. Danner, J. Mulder, C. Loveday, C. Christopherson, S. Kwok, J. Sninsky, and C. A. B. Boucher. 1995. Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant populations in persons treated with lamivudine (3TC). J: Infect. Dis. 171:1411-1419.
-
(1995)
J: Infect. Dis.
, vol.171
, pp. 1411-1419
-
-
Schuurman, R.1
Nijhuis, M.2
Van Leeuen, R.3
Schipper, P.4
De Jong, D.5
Collis, P.6
Danner, S.7
Mulder, J.8
Loveday, C.9
Christopherson, C.10
Kwok, S.11
Sninsky, J.12
Boucher, C.A.B.13
-
52
-
-
0028273314
-
Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations
-
Shafer, R. W., M. J. Kozal, M. A. Winters, A. K. N. Iversen, D. A. Katzenstein, M. V. Ragni, W. A. Meyer, P. Gupta, S. Rasheed, R. Coombs, M. Katzman, S. Ficus, and T. C. Merigan. 1994. Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations. J. Infect. Dis. 169:722-729.
-
(1994)
J. Infect. Dis.
, vol.169
, pp. 722-729
-
-
Shafer, R.W.1
Kozal, M.J.2
Winters, M.A.3
Iversen, A.K.N.4
Katzenstein, D.A.5
Ragni, M.V.6
Meyer, W.A.7
Gupta, P.8
Rasheed, S.9
Coombs, R.10
Katzman, M.11
Ficus, S.12
Merigan, T.C.13
-
53
-
-
0025950055
-
Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase
-
St. Clair, M. H., J. L. Martin, G. Tudor-Williams, M. C. Bach, C. L. Vavro, D. M. King, P. Kellam, S. D. Kemp, and B. A. Larder. 1991. Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase. Science 253:1557-1559.
-
(1991)
Science
, vol.253
, pp. 1557-1559
-
-
St. Clair, M.H.1
Martin, J.L.2
Tudor-Williams, G.3
Bach, M.C.4
Vavro, C.L.5
King, D.M.6
Kellam, P.7
Kemp, S.D.8
Larder, B.A.9
-
54
-
-
0000523078
-
Nucleotide sequence and genomic organization of feline immunodeficiency virus
-
Talbott, R. L., E. E. Sparger, K. M. Lovelace, W. M. Fitch, N. C. Pedersen, P. A. Luciw, and J. H. Elder. 1989. Nucleotide sequence and genomic organization of feline immunodeficiency virus. Proc. Natl. Acad. Sci. USA 86:5743-5747.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5743-5747
-
-
Talbott, R.L.1
Sparger, E.E.2
Lovelace, K.M.3
Fitch, W.M.4
Pedersen, N.C.5
Luciw, P.A.6
Elder, J.H.7
-
55
-
-
0027285372
-
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
-
Tisdale, M., S. D. Kemp, N. M. Parry, and B. A. Larder. 1993. Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proc. Natl. Acad. Sci. USA 90:5653-5656.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5653-5656
-
-
Tisdale, M.1
Kemp, S.D.2
Parry, N.M.3
Larder, B.A.4
-
56
-
-
13344294407
-
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase
-
Wainberg, M. A., W. C. Drosopoulos, H. Salomon, M. Hsu, G. Borkow, M. A. Parniak, Z. Gu, Q. Song, J. Manne, S. Islam, G. Castriota, and V. R. Prasad. 1996. Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase. Science 271:1282-1285.
-
(1996)
Science
, vol.271
, pp. 1282-1285
-
-
Wainberg, M.A.1
Drosopoulos, W.C.2
Salomon, H.3
Hsu, M.4
Borkow, G.5
Parniak, M.A.6
Gu, Z.7
Song, Q.8
Manne, J.9
Islam, S.10
Castriota, G.11
Prasad, V.R.12
-
57
-
-
0027415886
-
Clinical correlates and molecular basis of HIV drug resistance
-
Wainberg, M. A., Z. Gu, Q. Gao, E. Arts, R. Geleziunas, S. Bour, R. Beaulieu, C. Tsoukas, J. Singer, and J. Montaner. 1993. Clinical correlates and molecular basis of HIV drug resistance. J. Acquired Immune Defic. Syndr. 6(Suppl. 1):S36-S46.
-
(1993)
J. Acquired Immune Defic. Syndr.
, vol.6
, Issue.1 SUPPL.
-
-
Wainberg, M.A.1
Gu, Z.2
Gao, Q.3
Arts, E.4
Geleziunas, R.5
Bour, S.6
Beaulieu, R.7
Tsoukas, C.8
Singer, J.9
Montaner, J.10
-
58
-
-
0024058465
-
Pathogenesis of experimentally induced feline immunodeficiency virus infection in cats
-
Yamamoto, J. K., E. Sparger, E. W. Ho, P. R. Andersen, T. P. O'Connor, C. P. Mandell, L. Lowenstine, R. Munn, and N. C. Pedersen. 1988. Pathogenesis of experimentally induced feline immunodeficiency virus infection in cats. Am. J. Vet. Res. 49:1246-1258.
-
(1988)
Am. J. Vet. Res.
, vol.49
, pp. 1246-1258
-
-
Yamamoto, J.K.1
Sparger, E.2
Ho, E.W.3
Andersen, P.R.4
O'Connor, T.P.5
Mandell, C.P.6
Lowenstine, L.7
Munn, R.8
Pedersen, N.C.9
-
59
-
-
9544227480
-
Mutants of feline immunodeficiency virus resistant to 2′,3′-dideoxy-2′,3′-didehydrothymidine
-
Zhu, Y.-Q., K. M. Remington, and T. W. North. 1996. Mutants of feline immunodeficiency virus resistant to 2′,3′-dideoxy-2′,3′-didehydrothymidine. Antimicrob. Agents Chemother. 40:1983-1987.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 1983-1987
-
-
Zhu, Y.-Q.1
Remington, K.M.2
North, T.W.3
|